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ONTOLOGY REPORT - ANNOTATIONS


Term:sodium ion homeostasis
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Accession:GO:0055078 term browser browse the term
Definition:Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.



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sodium ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:45,141,870...45,159,255
Ensembl chr18:45,142,586...45,159,255
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:53,828,482...53,847,043
Ensembl chr17:53,813,976...53,847,167
JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in ISO (PMID:9838244) BHF-UCL PMID:9838244 NCBI chr13:36,866,476...36,880,625 JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,823,472...45,878,527
Ensembl chr15:45,823,560...45,876,463
JBrowse link
G EDNRB endothelin receptor type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:31,415,324...31,438,772
Ensembl chr22:31,417,308...31,437,587
JBrowse link
G EXT1 exostosin glycosyltransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6343289|PMID:31365577) MGI
Ensembl
PMID:31365577 GO_REF:0000107 MGI:6343289 NCBI chr13:17,172,497...17,457,084
Ensembl chr13:17,172,705...17,456,469
JBrowse link
G EXT2 exostosin glycosyltransferase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6343289|PMID:31365577) MGI
Ensembl
PMID:31365577 GO_REF:0000107 MGI:6343289 NCBI chr18:44,987,310...45,122,339
Ensembl chr18:44,987,748...45,129,974
JBrowse link
G MC3R melanocortin 3 receptor ISO RGD PMID:19570553 RGD:6484660 NCBI chr24:41,492,371...41,494,033
Ensembl chr24:41,492,371...41,494,033
JBrowse link
G SCN7A sodium voltage-gated channel alpha subunit 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3616303|PMID:16223844) MGI
Ensembl
PMID:16223844 GO_REF:0000107 MGI:3616303 NCBI chr36:11,482,840...11,590,394
Ensembl chr36:11,482,899...11,561,845
JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,612,206...38,638,212
Ensembl chr27:38,612,194...38,638,980
JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta acts_upstream_of_or_within
involved_in
ISO
ISS
IEA
(MGI:6478095|PMID:28567665) MGI
UniProt
Ensembl
PMID:28567665 GO_REF:0000024 GO_REF:0000107 MGI:6478095 NCBI chr 6:22,439,643...22,481,349
Ensembl chr 6:22,439,643...22,481,349
JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:22,566,568...22,593,479
Ensembl chr 6:22,567,711...22,593,503
JBrowse link
G SLC12A1 solute carrier family 12 member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:14,458,373...14,548,870
Ensembl chr30:14,459,606...14,547,694
JBrowse link
G SLC12A2 solute carrier family 12 member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:17,143,943...17,256,248
Ensembl chr11:17,143,943...17,253,695
JBrowse link
G SLC12A3 solute carrier family 12 member 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:59,413,737...59,449,129
Ensembl chr 2:59,413,828...59,449,081
JBrowse link
G SLC12A8 solute carrier family 12 member 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr33:28,085,345...28,200,779
Ensembl chr33:28,085,350...28,214,022
JBrowse link
G SLC9B2 solute carrier family 9 member B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:24,354,741...24,419,198
Ensembl chr32:24,360,050...24,417,372
JBrowse link
G UMOD uromodulin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6367886|PMID:29357410), (MGI:6406787|PMID:30007527) MGI
Ensembl
PMID:29357410 PMID:30007527 GO_REF:0000107 MGI:6367886 MGI:6406787 NCBI chr 6:24,991,459...25,006,735
Ensembl chr 6:24,991,459...25,006,735
JBrowse link
G UPK3A uroplakin 3A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3687098|PMID:12388410) MGI
Ensembl
PMID:12388410 GO_REF:0000107 MGI:3687098 NCBI chr10:20,747,139...20,755,131
Ensembl chr10:20,747,140...20,755,162
JBrowse link
intracellular sodium ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16380540 RGD:1582118 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:16380540 RGD:1582118 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853
JBrowse link
G ATP12A ATPase H+/K+ transporting non-gastric alpha2 subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:18,753,192...18,779,781
Ensembl chr25:18,753,872...18,779,831
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in IEA
IBA
Ensembl
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:53,828,482...53,847,043
Ensembl chr17:53,813,976...53,847,167
JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 1:112,325,988...112,346,056
Ensembl chr 1:112,325,289...112,346,916
JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr38:22,023,176...22,080,656
Ensembl chr38:22,023,221...22,080,604
JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 involved_in IEA TreeGrafter GO_REF:0000118
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 involved_in IEA
IBA
Ensembl
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:29,464,132...29,487,124
Ensembl chr 7:29,464,132...29,487,947
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 5:32,548,591...32,553,911
Ensembl chr 5:32,549,167...32,553,504
JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:37,684,507...37,727,535
Ensembl chr23:37,684,506...37,726,746
JBrowse link
G ATP4A ATPase H+/K+ transporting subunit alpha involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 1:117,103,937...117,116,779
Ensembl chr 1:117,103,620...117,116,778
JBrowse link
G ATP4B ATPase H+/K+ transporting subunit beta involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr22:60,898,801...60,904,223
Ensembl chr22:60,898,833...60,904,223
JBrowse link
G C7 complement C7 ISO RGD PMID:10792960 RGD:1599525 NCBI chr 4:68,450,660...68,502,753
Ensembl chr 4:68,451,578...68,513,386
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 involved_in ISO (PMID:19542013) ComplexPortal PMID:19542013 NCBI chr 5:15,812,335...15,824,552
Ensembl chr 5:15,815,969...15,823,057
JBrowse link
G IL1A interleukin 1 alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4414613|PMID:19766171) MGI
Ensembl
PMID:19766171 GO_REF:0000107 MGI:4414613 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 acts_upstream_of_or_within ISO (MGI:2181312|PMID:9689096) MGI PMID:9689096 MGI:2181312 NCBI chr15:46,390,030...46,718,000
Ensembl chr15:46,390,023...46,710,131
JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,612,206...38,638,212
Ensembl chr27:38,612,194...38,638,980
JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:22,439,643...22,481,349
Ensembl chr 6:22,439,643...22,481,349
JBrowse link
G SCNN1D sodium channel epithelial 1 subunit delta involved_in ISO (PMID:16423824) ComplexPortal PMID:16423824 NCBI chr 5:56,455,677...56,466,035
Ensembl chr 5:56,461,939...56,465,595
JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:22,566,568...22,593,479
Ensembl chr 6:22,567,711...22,593,503
JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO RGD PMID:11250940 RGD:628514 NCBI chr 1:27,086,431...27,196,601
Ensembl chr 1:27,087,361...27,196,521
JBrowse link
G SLC12A2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO (MGI:6392919|PMID:11940530) ARUK-UCL PMID:11940530 MGI:6392919 NCBI chr11:17,143,943...17,256,248
Ensembl chr11:17,143,943...17,253,695
JBrowse link
G SLC1A3 solute carrier family 1 member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4414613|PMID:19766171) MGI
Ensembl
PMID:19766171 GO_REF:0000107 MGI:4414613 NCBI chr 4:71,936,128...72,014,119
Ensembl chr 4:71,936,126...72,014,173
JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,004,207...32,381,399
Ensembl chr17:32,005,245...32,307,700
JBrowse link
G SLC9A1 solute carrier family 9 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:73,054,742...73,103,364
Ensembl chr 2:73,054,742...73,103,364
JBrowse link
G SPP1 secreted phosphoprotein 1 acts_upstream_of_or_within ISO (MGI:3763852|PMID:17898038) MGI PMID:17898038 MGI:3763852 NCBI chr32:11,354,070...11,362,325
Ensembl chr32:11,353,953...11,362,069
JBrowse link
G TMPRSS3 transmembrane serine protease 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:12393794) MGI
Ensembl
PMID:12393794 GO_REF:0000107 NCBI chr31:36,706,229...36,730,444
Ensembl chr31:36,707,723...36,730,520
JBrowse link
G UMOD uromodulin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3763852|PMID:17898038) MGI
Ensembl
PMID:17898038 GO_REF:0000107 MGI:3763852 NCBI chr 6:24,991,459...25,006,735
Ensembl chr 6:24,991,459...25,006,735
JBrowse link
negative regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPX spexin hormone involved_in ISO PMID:22038051 UniProt PMID:22038051 RGD:8693358 NCBI chr27:25,561,636...25,572,310
Ensembl chr27:25,563,606...25,571,093
JBrowse link
positive regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3608592|PMID:11566895) Ensembl
MGI
PMID:11566895 GO_REF:0000107 MGI:3608592 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G EDN1 endothelin 1 acts_upstream_of_or_within ISO (MGI:3051206|PMID:15314687) MGI PMID:15314687 MGI:3051206 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383
JBrowse link
regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORIN corin, serine peptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:43,501,287...43,737,522
Ensembl chr13:43,502,665...43,737,813
JBrowse link
renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6V1B1 ATPase H+ transporting V1 subunit B1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5529401|PMID:24051376) Ensembl
MGI
PMID:24051376 GO_REF:0000107 MGI:5529401 NCBI chr10:69,261,311...69,287,540
Ensembl chr10:69,252,926...69,287,542
JBrowse link
G COMT catechol-O-methyltransferase acts_upstream_of_or_within ISO (MGI:3838290|PMID:12188925), (MGI:6377798|PMID:19770404) MGI PMID:12188925 PMID:19770404 MGI:3838290 MGI:6377798 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008
JBrowse link
G EDNRB endothelin receptor type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:31,415,324...31,438,772
Ensembl chr22:31,417,308...31,437,587
JBrowse link
G MLLT6 MLLT6, PHD finger containing involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5644399|PMID:21546577) Ensembl
MGI
PMID:21546577 GO_REF:0000107 MGI:5644399 NCBI chr 9:23,504,750...23,526,747
Ensembl chr 9:23,506,959...23,526,690
JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 acts_upstream_of_or_within ISO (MGI:2181312|PMID:9689096) MGI PMID:9689096 MGI:2181312 NCBI chr15:46,390,030...46,718,000
Ensembl chr15:46,390,023...46,710,131
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17897
    homeostatic process 1925
      chemical homeostasis 1181
        inorganic ion homeostasis 579
          sodium ion homeostasis 48
            intracellular sodium ion homeostasis + 28
            renal sodium excretion + 9
Path 2
Term Annotations click to browse term
  biological_process 17897
    homeostatic process 1925
      chemical homeostasis 1181
        monoatomic ion homeostasis 660
          monoatomic cation homeostasis 647
            sodium ion homeostasis 48
              intracellular sodium ion homeostasis + 28
              renal sodium excretion + 9
paths to the root