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ONTOLOGY REPORT - ANNOTATIONS

Term:sodium ion homeostasis
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Accession:GO:0055078 term browser browse the term
Definition:Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.


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sodium ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 involved_in ISO (PMID:9838244) RGD PMID:9838244 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:102720 (MGI:3846009|PMID:18784261) RGD PMID:18784261 MGI:3846009 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO MGI:105923 (MGI:3846009|PMID:18784261) RGD PMID:18784261 MGI:3846009 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO MGI:108050 (MGI:6343289|PMID:31365577) RGD PMID:31365577 MGI:6343289 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Ext2 exostosin glycosyltransferase 2 acts_upstream_of_or_within ISO MGI:894663 (MGI:6343289|PMID:31365577) RGD PMID:31365577 MGI:6343289 NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059 		JBrowse link
G Mc3r melanocortin 3 receptor IEP RGD PMID:19570553 RGD:6484660 NCBI chr 3:161,016,347...161,017,444
Ensembl chr 3:161,016,347...161,017,444 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 acts_upstream_of_or_within ISO (MGI:3616303|PMID:16223844) RGD PMID:16223844 MGI:3616303 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha involved_in ISO
IEA
ISS		 (PMID:24124190)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24124190 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:24124190)
GO_REF:0000107
(MGI:6478095|PMID:28567665)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24124190 PMID:28567665 GO_REF:0000024 GO_REF:0000107 MGI:6478095 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma involved_in ISO
IEA
ISS		 (PMID:24124190)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24124190 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc12a3 solute carrier family 12 member 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:10,630,649...10,679,250
Ensembl chr19:10,631,393...10,669,091 		JBrowse link
G Tfap2b transcription factor AP-2 beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:2656435|PMID:12695560)		 UniProt
RGD		 PMID:12695560 GO_REF:0000024 MGI:2656435 NCBI chr 9:21,786,250...21,815,785
Ensembl chr 9:21,786,258...21,814,520 		JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (MGI:6367886|PMID:29357410), (MGI:6406787|PMID:30007527) RGD PMID:29357410 PMID:30007527 MGI:6367886 MGI:6406787 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
G Upk3a uroplakin 3A acts_upstream_of_or_within ISO MGI:2183244 (MGI:3687098|PMID:12388410) RGD PMID:12388410 MGI:3687098 NCBI chr 7:116,128,981...116,139,950
Ensembl chr 7:116,134,874...116,139,948 		JBrowse link
cellular sodium ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IMP RGD PMID:16380540 RGD:1582118 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:16380540 RGD:1582118 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Atp12a ATPase H+/K+ transporting non-gastric alpha2 subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:30,443,571...30,468,229
Ensembl chr15:30,443,571...30,468,229 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 involved_in ISO
IBA		 (PMID:10636900), (PMID:19542013)
PMID:21873635
(PMID:19542013)		 RGD PMID:10636900 PMID:19542013 PMID:21873635 RGD:13792537 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 involved_in ISO
IBA		 (PMID:10636900)
PMID:21873635		 RGD PMID:10636900 PMID:21873635 RGD:13792537 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 involved_in ISO
IBA		 (PMID:10636900)
(MGI:4352602|PMID:19376779)
PMID:21873635		 RGD PMID:10636900 PMID:19376779 PMID:21873635 MGI:4352602, RGD:13792537 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:84,683,766...84,719,790
Ensembl chr13:84,683,768...84,719,687 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 involved_in IBA
ISO		 PMID:21873635
(PMID:19542013)
(PMID:10636900), (PMID:19542013)		 RGD PMID:10636900 PMID:19542013 PMID:21873635 RGD:13792537 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:10636900), (PMID:19542013)		 Ensembl
RGD		 PMID:10636900 PMID:19542013 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 involved_in ISO
IBA		 (PMID:10636900), (PMID:19542013)
PMID:21873635		 RGD PMID:10636900 PMID:19542013 PMID:21873635 RGD:13792537 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598 		JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:85,961,607...85,974,972
Ensembl chr 1:85,961,708...85,974,844 		JBrowse link
G Atp4b ATPase H+/K+ transporting subunit beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:76,144,150...76,153,063
Ensembl chr16:76,144,150...76,153,063 		JBrowse link
G C7 complement C7 IMP RGD PMID:10792960 RGD:1599525 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535 		JBrowse link
G Chp2 calcineurin-like EF hand protein 2 TAS RGD PMID:12576672 RGD:1299552 NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139 		JBrowse link
G Il1a interleukin 1 alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4414613|PMID:19766171)		 Ensembl
RGD		 PMID:19766171 GO_REF:0000107 MGI:4414613 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 acts_upstream_of_or_within ISO MGI:2441654 (MGI:2181312|PMID:9689096) RGD PMID:9689096 MGI:2181312 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IDA RGD PMID:11250940 RGD:628514 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO (MGI:6392919|PMID:11940530) RGD PMID:11940530 MGI:6392919 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1931872 (MGI:4414613|PMID:19766171)		 Ensembl
RGD		 PMID:19766171 GO_REF:0000107 MGI:4414613 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO (PMID:1374913) RGD PMID:1374913 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISO (PMID:24840010) RGD PMID:24840010 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Spp1 secreted phosphoprotein 1 acts_upstream_of_or_within ISO (MGI:3763852|PMID:17898038) RGD PMID:17898038 MGI:3763852 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tmprss3 transmembrane serine protease 3 acts_upstream_of_or_within ISO (PMID:12393794) RGD PMID:12393794 NCBI chr20:9,254,102...9,273,808
Ensembl chr20:9,254,109...9,274,363 		JBrowse link
G Umod uromodulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3763852|PMID:17898038)		 Ensembl
RGD		 PMID:17898038 GO_REF:0000107 MGI:3763852 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
negative regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IMP RGD PMID:2966592 RGD:12880016 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:14993484 RGD:1625254 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Anpep alanyl aminopeptidase, membrane IMP RGD PMID:19996063 RGD:5131447 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 IMP RGD PMID:18596120 RGD:2301931 NCBI chr  X:151,633,501...151,636,000
Ensembl chr  X:151,633,522...151,635,989 		JBrowse link
G Comt catechol-O-methyltransferase IMP RGD PMID:10450019 RGD:8662342 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Gnas GNAS complex locus IMP RGD PMID:21895632 RGD:5509797 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Spx spexin hormone involved_in IDA PMID:22038051 UniProt PMID:22038051 RGD:8693358 NCBI chr 4:175,356,044...175,362,082
Ensembl chr 4:175,356,247...175,362,082 		JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:16531985 RGD:2306837 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237 		JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:16531985 RGD:2306837 NCBI chr10:106,438,092...106,439,252
Ensembl chr10:106,438,092...106,439,252 		JBrowse link
positive regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IMP
IDA		 in renal medulla RGD PMID:10070140 PMID:10070140 RGD:628573, RGD:628573 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Agt angiotensinogen IMP
IDA		 RGD PMID:16380540 PMID:22689743 RGD:1582118, RGD:8549474 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:16380540 RGD:1582118 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:18596120 RGD:2301931 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:1857875 (MGI:3608592|PMID:11566895) RGD PMID:11566895 MGI:3608592 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 IDA RGD PMID:14621190 RGD:1581467 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within ISO MGI:3044563|MGI:3054057 (MGI:3051206|PMID:15314687) RGD PMID:15314687 MGI:3051206 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:18305094 RGD:4892582 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:22459149 RGD:13507313 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Nppb natriuretic peptide B IDA RGD PMID:8289999 RGD:7247315 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:17559853 RGD:2304131 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:18287210 RGD:10003052 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Snx5 sorting nexin 5 IMP RGD PMID:23195037 RGD:13508622 NCBI chr 3:131,621,709...131,641,205
Ensembl chr 3:131,621,880...131,641,192 		JBrowse link
G Tac1 tachykinin, precursor 1 IDA RGD PMID:18364471 RGD:2304318 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:18364471 RGD:2304318 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:11390024 RGD:1582107 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Avp arginine vasopressin IMP RGD PMID:18596120 RGD:2301931 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Corin corin, serine peptidase involved_in IMP
ISO
IEA		 PMID:20613715
(MGI:5427566|PMID:22418978)
GO_REF:0000107		 RGD
Ensembl		 PMID:22418978 PMID:20613715 GO_REF:0000107 MGI:5427566, RGD:8553515 NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503 		JBrowse link
renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 acts_upstream_of_or_within ISO MGI:2673510 (MGI:5529401|PMID:24051376) RGD PMID:24051376 MGI:5529401 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO MGI:3693642 (MGI:3692691|PMID:16868309) RGD PMID:16868309 MGI:3692691 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Mllt6 MLLT6, PHD finger containing acts_upstream_of_or_within ISO MGI:3856248 (MGI:5644399|PMID:21546577) RGD PMID:21546577 MGI:5644399 NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    biological regulation 13476
      regulation of biological quality 4152
        homeostatic process 1993
          chemical homeostasis 1358
            ion homeostasis 870
              cation homeostasis 811
                metal ion homeostasis 739
                  sodium ion homeostasis 63
                    cellular sodium ion homeostasis + 24
                    renal sodium excretion + 28
paths to the root