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ONTOLOGY REPORT - ANNOTATIONS

Term:sodium ion homeostasis
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Accession:GO:0055078 term browser browse the term
Definition:Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.


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sodium ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 involved_in ISO (PMID:17408578) RGD PMID:17408578 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 involved_in ISO (PMID:9838244) RGD PMID:9838244 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO		 GO_REF:0000107
MGI:102720 (PMID:18784261)		 Ensembl
RGD		 PMID:18784261 GO_REF:0000107 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO MGI:105923 (PMID:18784261) RGD PMID:18784261 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO MGI:108050 (PMID:31365577) RGD PMID:31365577 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Ext2 exostosin glycosyltransferase 2 acts_upstream_of_or_within ISO MGI:894663 (PMID:31365577) RGD PMID:31365577 NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059 		JBrowse link
G Mc3r melanocortin 3 receptor IEP RGD PMID:19570553 RGD:6484660 NCBI chr 3:161,016,347...161,017,444
Ensembl chr 3:161,016,347...161,017,444 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA		 PMID:21084682
(PMID:26537257)
(PMID:16223844)
(PMID:17408578)
GO_REF:0000033		 RGD
GO_Central		 PMID:16223844 PMID:17408578 PMID:26537257 PMID:21084682 GO_REF:0000033, RGD:401966867 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha involved_in ISO
ISS		 (PMID:24124190)
GO_REF:0000024		 RGD
UniProt		 PMID:24124190 GO_REF:0000024 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:24124190)
GO_REF:0000024
(PMID:28567665)		 RGD
UniProt		 PMID:24124190 PMID:28567665 GO_REF:0000024 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma involved_in ISO
ISS		 (PMID:24124190)
GO_REF:0000024		 RGD
UniProt		 PMID:24124190 GO_REF:0000024 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc12a3 solute carrier family 12 member 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,630,651...10,679,250
Ensembl chr19:10,631,393...10,669,091 		JBrowse link
G Slc9b2 solute carrier family 9 member B2 involved_in ISO (PMID:27909897) RGD PMID:27909897 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225 		JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:29357410), (PMID:30007527) RGD PMID:29357410 PMID:30007527 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
G Upk3a uroplakin 3A acts_upstream_of_or_within ISO MGI:2183244 (PMID:12388410) RGD PMID:12388410 NCBI chr 7:116,128,981...116,139,950
Ensembl chr 7:116,134,874...116,139,948 		JBrowse link
intracellular sodium ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IMP RGD PMID:16380540 RGD:1582118 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:16380540 RGD:1582118 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Atp12a ATPase H+/K+ transporting non-gastric alpha2 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:30,443,571...30,468,229
Ensembl chr15:30,443,571...30,468,229 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 involved_in ISO
IBA
IEA		 (PMID:10636900), (PMID:19542013)
GO_REF:0000033
(PMID:19542013)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:10636900 PMID:19542013 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 involved_in ISO
IBA		 (PMID:10636900)
GO_REF:0000033		 RGD
GO_Central		 PMID:10636900 GO_REF:0000033 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 involved_in ISO
IBA
IEA		 (PMID:10636900)
GO_REF:0000033
(PMID:19376779)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:10636900 PMID:19376779 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:84,683,766...84,719,790
Ensembl chr13:84,683,768...84,719,687 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 involved_in ISO
IBA
IEA		 (PMID:10636900), (PMID:19542013)
GO_REF:0000033
GO_REF:0000107
(PMID:19542013)		 RGD
GO_Central
Ensembl		 PMID:10636900 PMID:19542013 GO_REF:0000033 GO_REF:0000107 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:10636900), (PMID:19542013)		 Ensembl
GO_Central
RGD		 PMID:10636900 PMID:19542013 GO_REF:0000033 GO_REF:0000107 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 involved_in ISO
IBA		 (PMID:10636900), (PMID:19542013)
GO_REF:0000033		 RGD
GO_Central		 PMID:10636900 PMID:19542013 GO_REF:0000033 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
Ensembl chr 8:96,910,309...96,941,598 		JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:85,961,607...85,974,972
Ensembl chr 1:85,961,708...85,974,844 		JBrowse link
G Atp4b ATPase H+/K+ transporting subunit beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:76,144,150...76,153,063
Ensembl chr16:76,144,150...76,153,063 		JBrowse link
G C7 complement C7 IMP RGD PMID:10792960 RGD:1599525 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535 		JBrowse link
G Chp2 calcineurin-like EF hand protein 2 TAS RGD PMID:12576672 RGD:1299552 NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139 		JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 involved_in ISO (PMID:19542013) RGD PMID:19542013 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203 		JBrowse link
G Il1a interleukin 1 alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19766171)		 Ensembl
RGD		 PMID:19766171 GO_REF:0000107 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 acts_upstream_of_or_within ISO MGI:2441654 (PMID:9689096) RGD PMID:9689096 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha involved_in ISO
IEA
IDA		 (PMID:16423824)
(PMID:15096495)
GO_REF:0000107
PMID:17562820		 RGD
Ensembl		 PMID:15096495 PMID:16423824 PMID:17562820 GO_REF:0000107, RGD:150521638 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in ISO
IDA
IEA		 (PMID:16423824)
(PMID:15096495)
PMID:17562820
GO_REF:0000107		 RGD
Ensembl		 PMID:15096495 PMID:16423824 PMID:17562820 GO_REF:0000107, RGD:150521638 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma involved_in ISO
IEA
IDA		 (PMID:16423824)
(PMID:15096495)
GO_REF:0000107
PMID:17562820		 RGD
Ensembl		 PMID:15096495 PMID:16423824 PMID:17562820 GO_REF:0000107, RGD:150521638 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IDA RGD PMID:11250940 RGD:628514 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO (PMID:11940530) RGD PMID:11940530 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1931872 (PMID:19766171)		 Ensembl
RGD		 PMID:19766171 GO_REF:0000107 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO
IEA		 (PMID:1374913)
GO_REF:0000107		 RGD
Ensembl		 PMID:1374913 GO_REF:0000107 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISO (PMID:24840010) RGD PMID:24840010 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Spp1 secreted phosphoprotein 1 acts_upstream_of_or_within ISO (PMID:17898038) RGD PMID:17898038 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tmprss3 transmembrane serine protease 3 acts_upstream_of_or_within ISO (PMID:12393794) RGD PMID:12393794 NCBI chr20:9,254,102...9,273,808
Ensembl chr20:9,254,109...9,274,363 		JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:17898038) RGD PMID:17898038 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
negative regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spx spexin hormone involved_in IDA PMID:22038051 UniProt PMID:22038051 RGD:8693358 NCBI chr 4:175,356,044...175,362,082
Ensembl chr 4:175,356,247...175,362,082 		JBrowse link
positive regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:1857875 (PMID:11566895) RGD PMID:11566895 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within ISO MGI:3044563|MGI:3054057 (PMID:15314687) RGD PMID:15314687 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Corin corin, serine peptidase involved_in IMP
ISO
IEA		 PMID:20613715
(PMID:22418978)
GO_REF:0000107		 RGD
Ensembl		 PMID:22418978 PMID:20613715 GO_REF:0000107, RGD:8553515 NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503 		JBrowse link
renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 acts_upstream_of_or_within ISO MGI:2673510 (PMID:24051376) RGD PMID:24051376 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO MGI:2178542 (PMID:12188925), (PMID:19770404) RGD PMID:12188925 PMID:19770404 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO MGI:3693642 (PMID:16868309) RGD PMID:16868309 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Mllt6 MLLT6, PHD finger containing acts_upstream_of_or_within ISO MGI:3856248 (PMID:21546577) RGD PMID:21546577 NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 acts_upstream_of_or_within ISO MGI:2441654 (PMID:9689096) RGD PMID:9689096 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    homeostatic process 2014
      chemical homeostasis 1225
        inorganic ion homeostasis 598
          sodium ion homeostasis 46
            intracellular sodium ion homeostasis + 28
            renal sodium excretion + 9
Path 2
Term Annotations click to browse term
  biological_process 20537
    homeostatic process 2014
      chemical homeostasis 1225
        monoatomic ion homeostasis 680
          monoatomic cation homeostasis 666
            sodium ion homeostasis 46
              intracellular sodium ion homeostasis + 28
              renal sodium excretion + 9
paths to the root