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ONTOLOGY REPORT - ANNOTATIONS


Term:gap junction hemi-channel activity
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Accession:GO:0055077 term browser browse the term
Definition:A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction.
Synonyms:exact_synonym: connexon channel activity


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gap junction hemi-channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA1 gap junction protein alpha 1 IMP (PMID:29366904) UniProt PMID:29366904 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJA3 gap junction protein alpha 3 IDA (PMID:30044662) UniProt PMID:30044662 NCBI chr13:20,138,252...20,161,327
Ensembl chr13:20,138,255...20,161,052
JBrowse link
G GJA5 gap junction protein alpha 5 IDA (PMID:23348765) BHF-UCL PMID:23348765 NCBI chr 1:147,756,199...147,781,127
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G PANX1 pannexin 1 NOT ISS UniProt GO_REF:0000024 NCBI chr11:94,128,841...94,185,596
Ensembl chr11:94,128,841...94,181,968
JBrowse link
G PANX2 pannexin 2 NOT ISS UniProt GO_REF:0000024 NCBI chr22:50,170,731...50,180,295
Ensembl chr22:50,170,731...50,180,295
JBrowse link
G PANX3 pannexin 3 NOT ISS UniProt GO_REF:0000024 NCBI chr11:124,611,428...124,620,356
Ensembl chr11:124,611,428...124,620,356
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18786
    transporter activity 1249
      transmembrane transporter activity 1104
        passive transmembrane transporter activity 502
          channel activity 501
            wide pore channel activity 30
              gap junction hemi-channel activity 6
Path 2
Term Annotations click to browse term
  molecular_function 18786
    transporter activity 1249
      transmembrane transporter activity 1104
        passive transmembrane transporter activity 502
          channel activity 501
            wide pore channel activity 30
              gap junction channel activity 24
                gap junction hemi-channel activity 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.