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ONTOLOGY REPORT - ANNOTATIONS


Term:ventricular cardiac muscle cell differentiation
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Accession:GO:0055012 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
Synonyms:exact_synonym: ventricular cardiomyocyte differentiation;   ventricular heart muscle cell differentiation



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ventricular cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(MGI:3830899|PMID:16680724)
UniProt
RGD
PMID:16680724 GO_REF:0000024 MGI:3830899 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Myocd myocardin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3052940 (PMID:21357509)
Ensembl
RGD
PMID:21357509 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within ISO MGI:1857622 (PMID:9428411) RGD PMID:9428411 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO MGI:1857851 (PMID:9428411) RGD PMID:9428411 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rxra retinoid X receptor alpha acts_upstream_of_or_within ISO MGI:2136274|MGI:98215 (PMID:9428411) RGD PMID:9428411 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta acts_upstream_of_or_within ISO MGI:1857822|MGI:98214 (PMID:9428411) RGD PMID:9428411 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
ventricular cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3050453|MGI:3663625 (PMID:17450150)
Ensembl
RGD
PMID:17450150 GO_REF:0000107 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO
GO_REF:0000107
(MGI:3695247|PMID:16798733)
Ensembl
RGD
PMID:16798733 GO_REF:0000107 MGI:3695247 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627
JBrowse link
G Ccnb1 cyclin B1 IEP RGD PMID:15253691 RGD:2301353 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdk1 cyclin-dependent kinase 1 IEP RGD PMID:15253691 RGD:2301353 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Fhl2 four and a half LIM domains 2 involved_in ISO
IEA
(MGI:3511603|PMID:15509787)
GO_REF:0000107
RGD
Ensembl
PMID:15509787 GO_REF:0000107 MGI:3511603 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:3784153|PMID:17332425) RGD PMID:17332425 MGI:3784153 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2177930 (PMID:14755333)
Ensembl
RGD
PMID:14755333 GO_REF:0000107 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Myh10 myosin heavy chain 10 acts_upstream_of_or_within ISO MGI:2386445|MGI:3052104 (PMID:12893741) RGD PMID:12893741 NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165
JBrowse link
G Nkx2-6 NK2 homeobox 6 involved_in ISO (MGI:1267297|PMID:9621431) RGD PMID:9621431 MGI:1267297 NCBI chr15:44,443,151...44,447,248
Ensembl chr15:44,443,101...44,447,247
JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857844|MGI:2386742 (PMID:18292603) RGD PMID:18292603 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293
JBrowse link
ventricular cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a involved_in IEA
ISO
GO_REF:0000107
(MGI:2429350|PMID:12379849)
Ensembl
RGD
PMID:12379849 GO_REF:0000107 MGI:2429350 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (PMID:19546853)
Ensembl
RGD
PMID:19546853 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:3830437 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular developmental process 4768
        cell differentiation 4767
          cardiocyte differentiation 207
            cardiac muscle cell differentiation 167
              ventricular cardiac muscle cell differentiation 20
                ventricular cardiac muscle cell development + 13
                ventricular cardiac muscle cell fate commitment 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            circulatory system development 1378
              heart development 747
                cardiac muscle tissue development 294
                  cardiac muscle cell differentiation 167
                    ventricular cardiac muscle cell differentiation 20
                      ventricular cardiac muscle cell development + 13
                      ventricular cardiac muscle cell fate commitment 0
paths to the root