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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac muscle cell differentiation
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Accession:GO:0055007 term browser browse the term
Definition:The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
Synonyms:exact_synonym: cardiomyocyte differentiation
 related_synonym: heart muscle cell differentiation


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cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain acts_upstream_of_or_within ISO (MGI:3692159|PMID:16121256) MGI PMID:16121256 MGI:3692159 NCBI chrNW_004936571:2,761,254...2,797,045 JBrowse link
G Akap13 A-kinase anchoring protein 13 involved_in ISO (MGI:5308772|PMID:20139090) UniProt PMID:20139090 MGI:5308772 NCBI chrNW_004936483:11,661,862...11,977,292 JBrowse link
G Alpk3 alpha kinase 3 involved_in ISO (MGI:2150538|PMID:11418590) BHF-UCL PMID:11418590 MGI:2150538 NCBI chrNW_004936483:16,862,194...16,913,791 JBrowse link
G Arid1a AT-rich interaction domain 1A acts_upstream_of_or_within ISO (MGI:5578697|PMID:24335282) MGI PMID:24335282 MGI:5578697 NCBI chrNW_004936474:11,148,857...11,197,312 JBrowse link
G Asb2 ankyrin repeat and SOCS box containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:1,813,569...1,849,805 JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link
G Calr calreticulin ISO RGD PMID:9011638 RGD:2326218 NCBI chrNW_004936659:1,994,695...1,999,070 JBrowse link
G Cby1 chibby family member 1, beta catenin antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:2,677,502...2,681,845 JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (MGI:4829405|PMID:20713518)
(MGI:3056209|PMID:15342473)
MGI PMID:15342473 PMID:20713518 MGI:3056209 MGI:4829405 NCBI chrNW_004936603:2,631,781...3,146,104 JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO (MGI:3790568|PMID:18400219)
(MGI:4881377|PMID:20691899)
(PMID:16137232)
RGD
MGI
BHF-UCL
PMID:16137232 PMID:18400219 PMID:20486789 PMID:20691899 MGI:3790568 MGI:4881377 RGD:5131636 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Gata6 GATA binding protein 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16137232)
(MGI:3790568|PMID:18400219)
BHF-UCL
Ensembl
MGI
PMID:16137232 PMID:18400219 GO_REF:0000107 MGI:3790568 NCBI chrNW_004936550:1,814,336...1,844,399 JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936673:1,394,743...1,399,726 JBrowse link
G Ift20 intraflagellar transport 20 acts_upstream_of_or_within ISO (MGI:4361064|PMID:19654211) MGI PMID:19654211 MGI:4361064 NCBI chrNW_004936538:4,484,484...4,491,688 JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO (MGI:4361064|PMID:19654211) MGI PMID:19654211 MGI:4361064 NCBI chrNW_004936720:1,041,216...1,168,725 JBrowse link
G Itgb1 integrin subunit beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:84974|PMID:9004034) MGI
Ensembl
PMID:9004034 GO_REF:0000107 MGI:84974 NCBI chrNW_004936574:1,465,981...1,495,717 JBrowse link
G Kdm6b lysine demethylase 6B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:1,077,318...1,099,082 JBrowse link
G LOC101959877 calcyclin binding protein ISO mRNA:increased expression:heart RGD PMID:16440310 RGD:2326117 NCBI chrNW_004936481:13,198,744...13,203,518 JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO (MGI:3820390|PMID:19035347)
(MGI:4881377|PMID:20691899)
MGI PMID:19035347 PMID:20691899 MGI:3820390 MGI:4881377 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:15,533,264...15,534,576 JBrowse link
G Myocd myocardin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2682181|PMID:14645532) Ensembl
MGI
PMID:14645532 GO_REF:0000107 MGI:2682181 NCBI chrNW_004936595:5,256,615...5,356,563 JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:3820390|PMID:19035347)
(MGI:1329801|PMID:10021345)
(MGI:3783941|PMID:17234970)
RGD
Ensembl
MGI
PMID:10021345 PMID:17234970 PMID:19035347 PMID:20486789 GO_REF:0000107 MGI:1329801 MGI:3783941 MGI:3820390 RGD:5131636 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
G Nox4 NADPH oxidase 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3689176|PMID:16775014) MGI
Ensembl
PMID:16775014 GO_REF:0000107 MGI:3689176 NCBI chrNW_004936736:230,465...394,859 JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Pitx2 paired like homeodomain 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3783941|PMID:17234970)
(MGI:2389284|PMID:12397115)
MGI
Ensembl
PMID:12397115 PMID:17234970 GO_REF:0000107 MGI:2389284 MGI:3783941 NCBI chrNW_004936563:1,713,294...1,732,431 JBrowse link
G Sik1 salt inducible kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:774,749...784,326 JBrowse link
G Sirt6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:2,387,162...2,394,066 JBrowse link
G Slc9a1 solute carrier family 9 member A1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3837281|PMID:19011045) MGI
Ensembl
PMID:19011045 GO_REF:0000107 MGI:3837281 NCBI chrNW_004936474:11,460,266...11,517,420 JBrowse link
G Sox6 SRY-box transcription factor 6 acts_upstream_of_or_within ISO (MGI:2678961|PMID:14530442) MGI PMID:14530442 MGI:2678961 NCBI chrNW_004936528:2,331,706...2,912,423 JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 ISO RGD PMID:25339194 RGD:13209018 NCBI chrNW_004936489:4,903,176...5,177,987 JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3783941|PMID:17234970) MGI
Ensembl
PMID:17234970 GO_REF:0000107 MGI:3783941 NCBI chrNW_004936558:7,230,361...7,243,651 JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4881377|PMID:20691899) Ensembl
MGI
PMID:20691899 GO_REF:0000107 MGI:4881377 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 acts_upstream_of_or_within ISO (MGI:1321047|PMID:9876177) MGI PMID:9876177 MGI:1321047 NCBI chrNW_004936596:451,483...453,892 JBrowse link
G Timm44 translocase of inner mitochondrial membrane 44 ISO RGD PMID:12388124 RGD:13463596 NCBI chrNW_004936588:4,902,462...4,917,081 JBrowse link
G Tsc1 TSC complex subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2137425|PMID:11438694) MGI
Ensembl
PMID:11438694 GO_REF:0000107 MGI:2137425 NCBI chrNW_004936487:19,331,183...19,386,841 JBrowse link
atrial cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fhl2 four and a half LIM domains 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15509787) BHF-UCL
Ensembl
PMID:15509787 GO_REF:0000107 NCBI chrNW_004936764:613,863...656,220 JBrowse link
G Nkx2-6 NK2 homeobox 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9621431) BHF-UCL
Ensembl
PMID:9621431 GO_REF:0000107 NCBI chrNW_004936555:7,111,678...7,114,944 JBrowse link
atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:6,810,678...6,813,186 JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3847383|PMID:18467625) MGI
Ensembl
PMID:18467625 GO_REF:0000107 MGI:3847383 NCBI chrNW_004936558:7,230,361...7,243,651 JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
atrioventricular node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936804:52,435...115,289 JBrowse link
G Maml1 mastermind like transcriptional coactivator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936739:1,006,273...1,051,338 JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4355491|PMID:19546853) MGI
Ensembl
PMID:19546853 GO_REF:0000107 MGI:4355491 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3040116|PMID:15109497) MGI
Ensembl
PMID:15109497 GO_REF:0000107 MGI:3040116 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936864:150,742...179,205 JBrowse link
G Wnt8a Wnt family member 8A involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chrNW_004936531:7,273,681...7,279,394 JBrowse link
cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:16,186,844...16,248,394 JBrowse link
G Alpk2 alpha kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:5,934,857...6,049,090 JBrowse link
G Alpk3 alpha kinase 3 acts_upstream_of_or_within ISO (MGI:5644402|PMID:21441111) MGI PMID:21441111 MGI:5644402 NCBI chrNW_004936483:16,862,194...16,913,791 JBrowse link
G Asb2 ankyrin repeat and SOCS box containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:1,813,569...1,849,805 JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO (MGI:3711608|PMID:17450150) MGI PMID:17450150 MGI:3711608 NCBI chrNW_004936602:1,938,720...2,179,239 JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3849772|PMID:19535499) MGI
Ensembl
PMID:19535499 GO_REF:0000107 MGI:3849772 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
G Cxadr CXADR Ig-like cell adhesion molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3587448|PMID:16079292) MGI
Ensembl
PMID:16079292 GO_REF:0000107 MGI:3587448 NCBI chrNW_004936505:9,971,393...10,032,238 JBrowse link
G Dicer1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (MGI:3774881|PMID:18256189) MGI PMID:18256189 MGI:3774881 NCBI chrNW_004936846:528,768...584,599 JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO (MGI:3711360|PMID:17322895) MGI PMID:17322895 MGI:3711360 NCBI chrNW_004936679:2,448,676...2,474,641 JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5648096|PMID:26039991) Ensembl
MGI
PMID:26039991 GO_REF:0000107 MGI:5648096 NCBI chrNW_004936526:6,014,745...6,022,213 JBrowse link
G LOC101957084 plectin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:8,194,124...8,252,139 JBrowse link
G LOC101966001 titin-cap involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:14,856,433...14,857,692 JBrowse link
G Lrrc10 leucine rich repeat containing 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5484795|PMID:23236519) MGI
Ensembl
PMID:23236519 GO_REF:0000107 MGI:5484795 NCBI chrNW_004936545:7,437,375...7,441,351 JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:5529574|PMID:23994610) MGI PMID:23994610 MGI:5529574 NCBI chrNW_004936589:2,280,803...2,390,179 JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5632243|PMID:25139234) MGI
Ensembl
PMID:25139234 GO_REF:0000107 MGI:5632243 NCBI chrNW_004936474:158,376...282,310 JBrowse link
G Myh11 myosin heavy chain 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:3,223,057...3,313,487 JBrowse link
G Myo18b myosin XVIIIB acts_upstream_of_or_within ISO (MGI:3821523|PMID:18761673) MGI PMID:18761673 MGI:3821523 NCBI chrNW_004936657:551,535...764,247 JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
G Sgcb sarcoglycan beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1352919|PMID:10678176) MGI
Ensembl
PMID:10678176 GO_REF:0000107 MGI:1352919 NCBI chrNW_004936482:15,150,805...15,163,340 JBrowse link
G Sgcd sarcoglycan delta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5790783|PMID:23695275) MGI
Ensembl
PMID:23695275 GO_REF:0000107 MGI:5790783 NCBI chrNW_004936515:6,278,631...6,908,193 JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in
acts_upstream_of_or_within
ISO (MGI:1927695|PMID:10967099)
(MGI:4867054|PMID:21302256)
BHF-UCL
MGI
PMID:10967099 PMID:21302256 MGI:1927695 MGI:4867054 NCBI chrNW_004936508:10,894,918...11,256,084 JBrowse link
G Speg striated muscle enriched protein kinase acts_upstream_of_or_within ISO (MGI:4830240|PMID:19118250) MGI PMID:19118250 MGI:4830240 NCBI chrNW_004936569:1,821,125...1,877,006 JBrowse link
G Ttn titin involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004936509:7,733,426...7,999,503 JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within ISO (MGI:1339868|PMID:10229225) MGI PMID:10229225 MGI:1339868 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Xirp1 xin actin binding repeat containing 1 acts_upstream_of_or_within ISO (MGI:3775114|PMID:17766470) MGI PMID:17766470 MGI:3775114 NCBI chrNW_004936473:28,434,910...28,444,146 JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2178865|PMID:11923874) MGI
Ensembl
PMID:11923874 GO_REF:0000107 MGI:2178865 NCBI chrNW_004936474:22,035,059...22,077,846 JBrowse link
cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:20,743,195...20,811,567 JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3847383|PMID:18467625) MGI
Ensembl
PMID:18467625 GO_REF:0000107 MGI:3847383 NCBI chrNW_004936558:7,230,361...7,243,651 JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5295932|PMID:21554246) MGI
Ensembl
PMID:21554246 GO_REF:0000107 MGI:5295932 NCBI chrNW_004936864:150,742...179,205 JBrowse link
G Wt1 WT1 transcription factor involved_in ISO (MGI:5285454|PMID:21654746) BHF-UCL PMID:21654746 MGI:5285454 NCBI chrNW_004936533:5,411,949...5,459,693 JBrowse link
cardiac muscle thin filament assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nebl nebulette involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936520:6,658,555...6,992,643 JBrowse link
cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin alpha cardiac muscle 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:87509|PMID:9114002) MGI
Ensembl
PMID:9114002 GO_REF:0000107 MGI:87509 NCBI chrNW_004936673:1,092,700...1,098,256 JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936654:271,067...313,251 JBrowse link
G Fhod3 formin homology 2 domain containing 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5436289|PMID:23213483) MGI
Ensembl
PMID:23213483 GO_REF:0000107 MGI:5436289 NCBI chrNW_004936517:8,614,384...9,044,894 JBrowse link
G LOC101966001 titin-cap involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:14,856,433...14,857,692 JBrowse link
G Myh10 myosin heavy chain 10 acts_upstream_of_or_within ISO (MGI:1099556|PMID:9356462) MGI PMID:9356462 MGI:1099556 NCBI chrNW_004936595:1,697,283...1,832,571 JBrowse link
G Myl2 myosin light chain 2 acts_upstream_of_or_within ISO (MGI:1194431|PMID:9422794) MGI PMID:9422794 MGI:1194431 NCBI chrNW_004936558:3,746,227...3,753,576 JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in ISO PMID:17885681 BHF-UCL PMID:17885681 RGD:8554371 NCBI chrNW_004936475:89,717...137,866 JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:16,804,129...16,853,539 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO (MGI:1931346|PMID:11239463) UniProt PMID:11239463 MGI:1931346 NCBI chrNW_004936504:4,762,251...4,799,789 JBrowse link
G Srf serum response factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3513738|PMID:15569937) MGI
Ensembl
PMID:15569937 GO_REF:0000107 MGI:3513738 NCBI chrNW_004936476:16,779,941...16,789,499 JBrowse link
G Ttn titin involved_in
acts_upstream_of_or_within
ISO (PMID:11846417), (PMID:9817758)
(MGI:3653555|PMID:16702235)
BHF-UCL
MGI
PMID:9817758 PMID:11846417 PMID:16702235 MGI:3653555 NCBI chrNW_004936509:7,733,426...7,999,503 JBrowse link
cardiac pacemaker cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shox2 short stature homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936519:4,810,777...4,818,733 JBrowse link
cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2664013|PMID:12782680) MGI
Ensembl
PMID:12782680 GO_REF:0000107 MGI:2664013 NCBI chrNW_004936757:149,366...237,710 JBrowse link
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO (MGI:2664013|PMID:12782680) MGI PMID:12782680 MGI:2664013 NCBI chrNW_004936515:3,523,799...3,572,467 JBrowse link
G Agt angiotensinogen ISO RGD PMID:21376054 RGD:5129173 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:21173078 RGD:6903878 NCBI chrNW_004936479:13,252,678...13,255,570 JBrowse link
G Akap13 A-kinase anchoring protein 13 ISO RGD PMID:18951085 RGD:2312638 NCBI chrNW_004936483:11,661,862...11,977,292 JBrowse link
G Camk2d calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:21554860 RGD:6907064 NCBI chrNW_004936563:4,226,412...4,526,139 JBrowse link
G Gata4 GATA binding protein 4 ISO RGD PMID:20971938 RGD:5131529 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO RGD PMID:27854077 RGD:13792737 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 ISO RGD PMID:9769323 RGD:7495831 NCBI chrNW_004936595:4,762,327...4,828,433 JBrowse link
G Myl2 myosin light chain 2 ISO RGD PMID:7657802 RGD:1580138 NCBI chrNW_004936558:3,746,227...3,753,576 JBrowse link
G Myocd myocardin ISO RGD PMID:18772130 RGD:5132877 NCBI chrNW_004936595:5,256,615...5,356,563 JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:7657802 RGD:1580138 NCBI chrNW_004936474:671,362...673,610 JBrowse link
G Nppb natriuretic peptide B ISO RGD PMID:7657802 RGD:1580138 NCBI chrNW_004936474:683,325...684,662 JBrowse link
G Pdlim5 PDZ and LIM domain 5 involved_in ISO PMID:24743145 BHF-UCL PMID:24743145 RGD:10054083 NCBI chrNW_004936687:1,944,095...2,152,501 JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 ISO RGD PMID:19542178 RGD:7775063 NCBI chrNW_004936787:330,390...1,491,994 JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 involved_in ISO PMID:24743145 BHF-UCL PMID:24743145 RGD:10054083 NCBI chrNW_004936554:3,593,607...3,797,324 JBrowse link
His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:6,810,678...6,813,186 JBrowse link
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936787:307,290...309,963 JBrowse link
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Ccnd2 cyclin D2 ISO RGD PMID:27302109 RGD:151660350 NCBI chrNW_004936606:4,474,801...4,496,158 JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936787:307,290...309,963 JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004937098:212,704...220,589 JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936545:7,286,018...7,407,623 JBrowse link
G Fzd7 frizzled class receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936726:1,256,684...1,275,324 JBrowse link
G Hdac3 histone deacetylase 3 acts_upstream_of_or_within ISO (MGI:5571645|PMID:24565863) MGI PMID:24565863 MGI:5571645 NCBI chrNW_004936504:12,530,546...12,546,556 JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:2,331,706...2,912,423 JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 ISO RGD PMID:21170593 RGD:6784534 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
G Ctdp1 CTD phosphatase subunit 1 ISO RGD PMID:22569295 RGD:9686371 NCBI chrNW_004936616:369,306...407,083 JBrowse link
G Foxp1 forkhead box P1 ISO RGD PMID:26333362 RGD:11561912 NCBI chrNW_004936603:2,631,781...3,146,104 JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO RGD PMID:24190878 RGD:10449133 NCBI chrNW_004936809:1,269,900...1,285,853 JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:266,462...277,256 JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 ISO RGD PMID:22082674 RGD:11533929 NCBI chrNW_004936498:6,001,126...6,135,663 JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3810223|PMID:17909105) MGI
Ensembl
PMID:17909105 GO_REF:0000107 MGI:3810223 NCBI chrNW_004936476:22,472,505...22,485,593 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO RGD PMID:22198280 RGD:5687133 NCBI chrNW_004936629:3,672,445...3,725,645 JBrowse link
G Rbm10 RNA binding motif protein 10 ISO RGD PMID:30257214 RGD:151667449 NCBI chrNW_004936502:12,923,890...12,952,179 JBrowse link
G Rgs2 regulator of G protein signaling 2 ISO RGD PMID:16380388 RGD:13524577 NCBI chrNW_004936638:1,065,866...1,068,649 JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:9918533 RGD:7207376 NCBI chrNW_004937238:101,948...109,513 JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 ISO RGD PMID:25022898 RGD:13464131 NCBI chrNW_004936630:2,906,573...2,938,837 JBrowse link
G Yy1 YY1 transcription factor ISO RGD PMID:18632988 RGD:9588273 NCBI chrNW_004936604:3,911,407...3,945,405 JBrowse link
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5432296|PMID:22711842) MGI
Ensembl
PMID:22711842 GO_REF:0000107 MGI:5432296 NCBI chrNW_004936477:3,354,336...3,445,248 JBrowse link
positive regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Efnb2 ephrin B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:5,138,751...5,181,630 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (MGI:5784966|PMID:24974728) BHF-UCL PMID:24974728 MGI:5784966 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Kat2a lysine acetyltransferase 2A ISO RGD PMID:20835911 RGD:8693751 NCBI chrNW_004936490:16,952,698...16,960,424 JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Myocd myocardin involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936595:5,256,615...5,356,563 JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (PMID:25163461) BHF-UCL PMID:25163461 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Wnt3a Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936864:150,742...179,205 JBrowse link
positive regulation of cardiac muscle fiber development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:18194989 RGD:5129139 NCBI chrNW_004936486:4,400,467...4,401,588 JBrowse link
G Akap6 A-kinase anchoring protein 6 ISO RGD PMID:16306226 PMID:21550986 RGD:2312613 RGD:6902940 NCBI chrNW_004936494:6,744,923...7,228,670 JBrowse link
G Ccn4 cellular communication network factor 4 ISO RGD PMID:21376054 RGD:5129173 NCBI chrNW_004936470:16,110,492...16,134,065 JBrowse link
G Ddx39b DExD-box helicase 39B ISO RGD PMID:20116367 RGD:10401141 NCBI chrNW_004936727:1,968,032...1,980,789 JBrowse link
G Edn1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:885,489...892,292 JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:12724418 RGD:2312280 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Fdps farnesyl diphosphate synthase ISO RGD PMID:19716825 RGD:2316294 NCBI chrNW_004936580:4,799,354...4,808,406 JBrowse link
G Igf1 insulin like growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G LOC101972117 hepcidin antimicrobial peptide ISO RGD PMID:24424338 RGD:11041632 NCBI chrNW_004936570:1,009,344...1,010,654 JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:21318349 PMID:21933187 RGD:10040977 RGD:10040978 NCBI chrNW_004936474:158,376...282,310 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:22989630 RGD:7174736 NCBI chrNW_004936504:10,960,069...11,056,834 JBrowse link
G Parp2 poly(ADP-ribose) polymerase 2 ISO RGD PMID:23261455 RGD:13514044 NCBI chrNW_004936877:554,969...564,905 JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:23487407 RGD:8693424 NCBI chrNW_004936659:309,530...321,294 JBrowse link
G Sirt1 sirtuin 1 ISO RGD PMID:25281201 RGD:13514043 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Slc25a4 solute carrier family 25 member 4 ISO RGD PMID:21325829 RGD:9681466 NCBI chrNW_004936554:4,130,461...4,135,046 JBrowse link
G Trip10 thyroid hormone receptor interactor 10 ISO RGD PMID:23915320 RGD:11535145 NCBI chrNW_004936588:4,035,370...4,044,751 JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3785685|PMID:17250822) MGI
Ensembl
PMID:17250822 GO_REF:0000107 MGI:3785685 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col14a1 collagen type XIV alpha 1 chain acts_upstream_of_or_within ISO (MGI:5444801|PMID:22906538) MGI PMID:22906538 MGI:5444801 NCBI chrNW_004936470:26,440,606...26,643,015 JBrowse link
sinoatrial node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bves blood vessel epicardial substance acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5424322|PMID:22354168) MGI
Ensembl
PMID:22354168 GO_REF:0000107 MGI:5424322 NCBI chrNW_004936564:1,791,733...1,823,421 JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936480:15,805,259...15,817,854 JBrowse link
G Popdc2 popeye domain containing 2 acts_upstream_of_or_within ISO (MGI:5424322|PMID:22354168) MGI PMID:22354168 MGI:5424322 NCBI chrNW_004936536:6,562,583...6,582,407 JBrowse link
G Shox2 short stature homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936519:4,810,777...4,818,733 JBrowse link
G Tbx18 T-box transcription factor 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936510:6,366,450...6,396,056 JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4366226|PMID:19096026) MGI
Ensembl
PMID:19096026 GO_REF:0000107 MGI:4366226 NCBI chrNW_004936558:7,230,361...7,243,651 JBrowse link
sinoatrial node cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:15,533,264...15,534,576 JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box transcription factor 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936510:6,366,450...6,396,056 JBrowse link
ventricular cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3711608|PMID:17450150) Ensembl
MGI
PMID:17450150 GO_REF:0000107 MGI:3711608 NCBI chrNW_004936564:2,759,085...2,885,394 JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936491:13,180,086...13,186,004 JBrowse link
G Ccnb1 cyclin B1 ISO RGD PMID:15253691 RGD:2301353 NCBI chrNW_004936480:400,287...407,677 JBrowse link
G Cdk1 cyclin dependent kinase 1 ISO RGD PMID:15253691 RGD:2301353 NCBI chrNW_004936614:2,300,682...2,313,611 JBrowse link
G Fhl2 four and a half LIM domains 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15509787) BHF-UCL
Ensembl
PMID:15509787 GO_REF:0000107 NCBI chrNW_004936764:613,863...656,220 JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936639:3,705,225...3,714,696 JBrowse link
G Lmna lamin A/C acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3027329|PMID:14755333) MGI
Ensembl
PMID:14755333 GO_REF:0000107 MGI:3027329 NCBI chrNW_004936580:5,374,208...5,395,442 JBrowse link
G Myh10 myosin heavy chain 10 acts_upstream_of_or_within ISO (MGI:3052228|PMID:12893741) MGI PMID:12893741 MGI:3052228 NCBI chrNW_004936595:1,697,283...1,832,571 JBrowse link
G Nkx2-6 NK2 homeobox 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9621431) BHF-UCL
Ensembl
PMID:9621431 GO_REF:0000107 NCBI chrNW_004936555:7,111,678...7,114,944 JBrowse link
G Pitx2 paired like homeodomain 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3841866|PMID:18292603) MGI
Ensembl
PMID:18292603 GO_REF:0000107 MGI:3841866 NCBI chrNW_004936563:1,713,294...1,732,431 JBrowse link
ventricular cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:3830899|PMID:16680724) UniProt PMID:16680724 MGI:3830899 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Myocd myocardin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4941650|PMID:21357509) MGI
Ensembl
PMID:21357509 GO_REF:0000107 MGI:4941650 NCBI chrNW_004936595:5,256,615...5,356,563 JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) BHF-UCL PMID:9553078 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Rara retinoic acid receptor alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1101382|PMID:9428411) MGI
Ensembl
PMID:9428411 GO_REF:0000107 MGI:1101382 NCBI chrNW_004936490:15,376,217...15,420,638 JBrowse link
G Rarb retinoic acid receptor beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1101382|PMID:9428411) MGI
Ensembl
PMID:9428411 GO_REF:0000107 MGI:1101382 NCBI chrNW_004936473:16,983,829...17,146,517 JBrowse link
G Rxra retinoid X receptor alpha acts_upstream_of_or_within ISO (MGI:1101382|PMID:9428411) MGI PMID:9428411 MGI:1101382 NCBI chrNW_004936669:2,735,111...2,763,060 JBrowse link
G Rxrb retinoid X receptor beta acts_upstream_of_or_within ISO (MGI:1101382|PMID:9428411) MGI PMID:9428411 MGI:1101382 NCBI chrNW_004936476:25,655,164...25,662,369 JBrowse link
ventricular cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:3,837,891...3,982,334 JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4355491|PMID:19546853) MGI
Ensembl
PMID:19546853 GO_REF:0000107 MGI:4355491 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
G Prox1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936628:4,185,712...4,240,680 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14975
    cellular process 13962
      cellular developmental process 3885
        cell differentiation 3862
          cardiocyte differentiation 181
            cardiac muscle cell differentiation 145
              His-Purkinje system cell differentiation + 4
              atrial cardiac muscle cell differentiation + 2
              cardiac muscle cell development + 101
              cardiac muscle cell fate commitment + 10
              cardiac pacemaker cell differentiation + 11
              negative regulation of cardiac muscle cell differentiation + 9
              positive regulation of cardiac muscle cell differentiation + 10
              regulation of cardiac muscle cell differentiation + 19
              ventricular cardiac muscle cell differentiation + 20
Path 2
Term Annotations click to browse term
  biological_process 14975
    developmental process 5970
      anatomical structure development 5593
        multicellular organism development 4821
          system development 4404
            circulatory system development 1153
              heart development 655
                cardiac muscle tissue development 253
                  cardiac muscle cell differentiation 145
                    His-Purkinje system cell differentiation + 4
                    atrial cardiac muscle cell differentiation + 2
                    cardiac muscle cell development + 101
                    cardiac muscle cell fate commitment + 10
                    cardiac pacemaker cell differentiation + 11
                    negative regulation of cardiac muscle cell differentiation + 9
                    positive regulation of cardiac muscle cell differentiation + 10
                    regulation of cardiac muscle cell differentiation + 19
                    ventricular cardiac muscle cell differentiation + 20
paths to the root