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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac muscle cell differentiation
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Accession:GO:0055007 term browser browse the term
Definition:The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
Synonyms:exact_synonym: cardiomyocyte differentiation
 related_synonym: heart muscle cell differentiation


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cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-Coenzyme A dehydrogenase, medium chain acts_upstream_of_or_within IMP (MGI:3692159|PMID:16121256) MGI PMID:16121256 MGI:3692159 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269 		JBrowse link
G Akap13 A kinase (PRKA) anchor protein 13 involved_in IMP (MGI:5308772|PMID:20139090) UniProt PMID:20139090 MGI:5308772 NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357 		JBrowse link
G Alpk3 alpha-kinase 3 involved_in IMP (MGI:2150538|PMID:11418590) BHF-UCL PMID:11418590 MGI:2150538 NCBI chr 7:80,707,321...80,755,360
Ensembl chr 7:80,707,348...80,755,360 		JBrowse link
G Arid1a AT rich interactive domain 1A (SWI-like) acts_upstream_of_or_within IMP (MGI:5578697|PMID:24335282) MGI PMID:24335282 MGI:5578697 NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080 		JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:103,287,401...103,322,260
Ensembl chr12:103,287,401...103,322,260 		JBrowse link
G AW551984 expressed sequence AW551984 acts_upstream_of_or_within IMP (MGI:5295932|PMID:21554246) MGI PMID:21554246 MGI:5295932 NCBI chr 9:39,498,692...39,516,070
Ensembl chr 9:39,498,692...39,515,699 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IGI		 (MGI:4939577|PMID:21145505) MGI
BHF-UCL		 PMID:21145505 GO_REF:0000096 MGI:4834177 MGI:4939577 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in NAS
IGI		 (MGI:5142394|PMID:9857019)
(MGI:4939577|PMID:21145505)		 UniProt
BHF-UCL		 PMID:9857019 PMID:21145505 MGI:4939577 MGI:5142394 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bvht braveheart long non-coding RNA acts_upstream_of_or_within_positive_effect IMP (MGI:5559147|PMID:23352431) MGI PMID:23352431 MGI:5559147 NCBI chr18:61,772,724...61,780,556
Ensembl chr18:61,772,613...61,780,543 		JBrowse link
G Cacybp calcyclin binding protein involved_in ISO mRNA:increased expression:heart RGD
MGI		 PMID:16440310 GO_REF:0000096 MGI:4417868 RGD:2326117 NCBI chr 1:160,029,937...160,040,462
Ensembl chr 1:160,029,937...160,040,445 		JBrowse link
G Calr calreticulin ISO RGD PMID:9011638 RGD:2326218 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Cby1 chibby family member 1, beta catenin antagonist involved_in IMP (MGI:3768203|PMID:17261658) UniProt PMID:17261658 MGI:3768203 NCBI chr15:79,543,357...79,551,863
Ensembl chr15:79,543,400...79,551,861 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within IMP (MGI:3056209|PMID:15342473)
(MGI:4829405|PMID:20713518)		 MGI PMID:15342473 PMID:20713518 MGI:3056209 MGI:4829405 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within
involved_in		 IGI
ISO
NAS
IEP
IMP		 (MGI:4881377|PMID:20691899)
(MGI:5013486|PMID:21556048)
(PMID:16137232)
(MGI:3790568|PMID:18400219)		 MGI
RGD
UniProt
BHF-UCL		 PMID:16137232 PMID:18400219 PMID:20486789 PMID:20691899 PMID:21556048 MGI:3790568 MGI:4881377 MGI:5013486 RGD:5131636 NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141 		JBrowse link
G Gata6 GATA binding protein 6 acts_upstream_of_or_within IGI
IEP
IMP		 (MGI:3790568|PMID:18400219)
(PMID:16137232)		 MGI
BHF-UCL		 PMID:16137232 PMID:18400219 MGI:3790568 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IDA (MGI:5315691|PMID:18545679) BHF-UCL PMID:18545679 MGI:5315691 NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in TAS (MGI:5901795|PMID:27783597) MGI PMID:27783597 MGI:5901795 NCBI chr 8:57,774,018...57,777,552
Ensembl chr 8:57,774,018...57,777,668 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 ISO RGD PMID:22021094 RGD:7495752 NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683 		JBrowse link
G Ift20 intraflagellar transport 20 acts_upstream_of_or_within IMP (MGI:4361064|PMID:19654211) MGI PMID:19654211 MGI:4361064 NCBI chr11:78,427,187...78,432,558
Ensembl chr11:78,427,187...78,432,563 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within IMP (MGI:4361064|PMID:19654211) MGI PMID:19654211 MGI:4361064 NCBI chr14:57,661,519...57,755,393
Ensembl chr14:57,661,519...57,755,393 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) acts_upstream_of_or_within IMP (MGI:84974|PMID:9004034) MGI PMID:9004034 MGI:84974 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681 		JBrowse link
G Kdm6b KDM1 lysine (K)-specific demethylase 6B involved_in IMP (MGI:5574281|PMID:23856522) BHF-UCL PMID:23856522 MGI:5574281 NCBI chr11:69,289,334...69,311,188
Ensembl chr11:69,289,334...69,304,501 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in
acts_upstream_of_or_within		 NAS
IGI		 (MGI:5013486|PMID:21556048)
(MGI:4881377|PMID:20691899)
(MGI:3820390|PMID:19035347)		 UniProt
MGI		 PMID:19035347 PMID:20691899 PMID:21556048 MGI:3820390 MGI:4881377 MGI:5013486 NCBI chr13:83,652,136...83,815,198
Ensembl chr13:83,652,153...83,815,199 		JBrowse link
G Mesp1 mesoderm posterior 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:79,441,989...79,443,338
Ensembl chr 7:79,441,989...79,443,536 		JBrowse link
G Mylk2 myosin, light polypeptide kinase 2, skeletal muscle involved_in NAS (MGI:5013486|PMID:21556048) UniProt PMID:21556048 MGI:5013486 NCBI chr 2:152,753,265...152,764,985
Ensembl chr 2:152,753,272...152,764,988 		JBrowse link
G Myocd myocardin involved_in
acts_upstream_of_or_within		 IMP
IBA		 (MGI:2136697|PMID:11439182)
(MGI:2682181|PMID:14645532)
(MGI:6201960|PMID:21873635)		 BHF-UCL
MGI
GO_Central		 PMID:11439182 PMID:14645532 PMID:21873635 MGI:2136697 MGI:2682181 MGI:6201960 NCBI chr11:65,064,434...65,160,815
Ensembl chr11:65,067,387...65,160,815 		JBrowse link
G Myod1 myogenic differentiation 1 involved_in NAS (MGI:5013486|PMID:21556048) UniProt PMID:21556048 MGI:5013486 NCBI chr 7:46,025,898...46,028,516
Ensembl chr 7:46,025,898...46,028,523 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 TAS
ISO
IGI
IDA
IMP		 (MGI:3828404|PMID:16137232)
(MGI:3820390|PMID:19035347)
(MGI:5142394|PMID:9857019)
(MGI:3783941|PMID:17234970)
(MGI:1329801|PMID:10021345)		 BHF-UCL
RGD
MGI
UniProt		 PMID:9857019 PMID:10021345 PMID:16137232 PMID:17234970 PMID:19035347 More... MGI:1329801 MGI:3783941 MGI:3820390 MGI:3828404 MGI:5142394 RGD:5131636 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Nox4 NADPH oxidase 4 acts_upstream_of_or_within IMP (MGI:3689176|PMID:16775014) MGI PMID:16775014 MGI:3689176 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918 		JBrowse link
G Nrg1 neuregulin 1 involved_in IMP (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Pax3 paired box 3 involved_in NAS (MGI:5013486|PMID:21556048) UniProt PMID:21556048 MGI:5013486 NCBI chr 1:78,077,904...78,173,773
Ensembl chr 1:78,077,904...78,173,771 		JBrowse link
G Pitx2 paired-like homeodomain transcription factor 2 acts_upstream_of_or_within IMP (MGI:3783941|PMID:17234970)
(MGI:2389284|PMID:12397115)		 MGI PMID:12397115 PMID:17234970 MGI:2389284 MGI:3783941 NCBI chr 3:128,993,527...129,013,243
Ensembl chr 3:128,993,527...129,013,240 		JBrowse link
G Rxra retinoid X receptor alpha involved_in TAS (MGI:4943617|PMID:20299672) DFLAT PMID:20299672 MGI:4943617 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Sik1 salt inducible kinase 1 involved_in IMP (MGI:4437512|PMID:20140255) UniProt PMID:20140255 MGI:4437512 NCBI chr17:32,063,222...32,074,808
Ensembl chr17:32,063,224...32,074,778 		JBrowse link
G Sirt6 sirtuin 6 involved_in IMP (MGI:6284084|PMID:29555651) UniProt PMID:29555651 MGI:6284084 NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631 		JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 acts_upstream_of_or_within IMP (MGI:3837281|PMID:19011045) MGI PMID:19011045 MGI:3837281 NCBI chr 4:133,097,022...133,151,013
Ensembl chr 4:133,097,017...133,151,013 		JBrowse link
G Sox6 SRY (sex determining region Y)-box 6 acts_upstream_of_or_within IDA (MGI:2678961|PMID:14530442) MGI PMID:14530442 MGI:2678961 NCBI chr 7:115,070,107...115,639,186
Ensembl chr 7:115,070,107...115,638,031 		JBrowse link
G Syne1 spectrin repeat containing, nuclear envelope 1 ISO RGD PMID:25339194 RGD:13209018 NCBI chr10:4,970,192...5,501,013
Ensembl chr10:4,970,917...5,501,482 		JBrowse link
G T brachyury, T-box transcription factor T involved_in NAS (MGI:5142394|PMID:9857019) UniProt PMID:9857019 MGI:5142394 NCBI chr17:8,653,255...8,661,328
Ensembl chr17:8,653,255...8,661,328 		JBrowse link
G Tbx3 T-box 3 acts_upstream_of_or_within IMP (MGI:3783941|PMID:17234970) MGI PMID:17234970 MGI:3783941 NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789 		JBrowse link
G Tbx5 T-box 5 involved_in
acts_upstream_of_or_within		 IMP
IGI		 (MGI:3833825|PMID:11431700)
(MGI:4881377|PMID:20691899)		 BHF-UCL
MGI		 PMID:11431700 PMID:20691899 MGI:3833825 MGI:4881377 NCBI chr 5:119,934,581...120,023,285
Ensembl chr 5:119,970,733...120,023,284 		JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 acts_upstream_of_or_within IMP (MGI:1321047|PMID:9876177) MGI PMID:9876177 MGI:1321047 NCBI chr 9:110,768,676...110,775,226
Ensembl chr 9:110,768,671...110,775,226 		JBrowse link
G Timm44 translocase of inner mitochondrial membrane 44 ISO RGD PMID:12388124 RGD:13463596 NCBI chr 8:4,309,731...4,325,905
Ensembl chr 8:4,309,731...4,325,913 		JBrowse link
G Tsc1 TSC complex subunit 1 acts_upstream_of_or_within IMP (MGI:2137425|PMID:11438694) MGI PMID:11438694 MGI:2137425 NCBI chr 2:28,531,005...28,581,184
Ensembl chr 2:28,531,240...28,581,179 		JBrowse link
atrial cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fhl2 four and a half LIM domains 2 acts_upstream_of_or_within IEP (PMID:15509787) BHF-UCL PMID:15509787 NCBI chr 1:43,162,231...43,237,503
Ensembl chr 1:43,162,234...43,236,144 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in TAS (MGI:1267297|PMID:9621431) BHF-UCL PMID:9621431 MGI:1267297 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Nkx2-6 NK2 homeobox 6 acts_upstream_of_or_within IEP (PMID:9621431) BHF-UCL PMID:9621431 NCBI chr14:69,409,251...69,412,989
Ensembl chr14:69,409,251...69,412,967 		JBrowse link
atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 Iroquois related homeobox 3 involved_in IMP (MGI:6101691|PMID:26786475) BHF-UCL PMID:26786475 MGI:6101691 NCBI chr 8:92,525,139...92,528,282
Ensembl chr 8:92,525,153...92,528,695 		JBrowse link
G Tbx3 T-box 3 acts_upstream_of_or_within IMP (MGI:3847383|PMID:18467625) MGI PMID:18467625 MGI:3847383 NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789 		JBrowse link
G Tbx5 T-box 5 involved_in IMP (MGI:3051695|PMID:15289437) BHF-UCL PMID:15289437 MGI:3051695 NCBI chr 5:119,934,581...120,023,285
Ensembl chr 5:119,970,733...120,023,284 		JBrowse link
atrioventricular node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor, type 1A involved_in IMP (MGI:3822612|PMID:17998461) BHF-UCL PMID:17998461 MGI:3822612 NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298 		JBrowse link
G Maml1 mastermind like transcriptional coactivator 1 involved_in IMP (MGI:5000164|PMID:21266778) BHF-UCL PMID:21266778 MGI:5000164 NCBI chr11:50,146,458...50,183,955
Ensembl chr11:50,146,461...50,183,138 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within IMP (MGI:4355491|PMID:19546853) MGI PMID:19546853 MGI:4355491 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Tbx5 T-box 5 involved_in IMP (MGI:3051695|PMID:15289437) BHF-UCL PMID:15289437 MGI:3051695 NCBI chr 5:119,934,581...120,023,285
Ensembl chr 5:119,970,733...120,023,284 		JBrowse link
atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within IMP (MGI:3040116|PMID:15109497) MGI PMID:15109497 MGI:3040116 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Tbx5 T-box 5 involved_in IMP (MGI:3051695|PMID:15289437) BHF-UCL PMID:15289437 MGI:3051695 NCBI chr 5:119,934,581...120,023,285
Ensembl chr 5:119,970,733...120,023,284 		JBrowse link
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a wingless-type MMTV integration site family, member 3A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:59,138,862...59,181,577
Ensembl chr11:59,138,859...59,181,578 		JBrowse link
G Wnt8a wingless-type MMTV integration site family, member 8A involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr18:34,675,380...34,681,114
Ensembl chr18:34,675,366...34,681,326 		JBrowse link
cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in IMP (MGI:4366185|PMID:19815520) UniProt PMID:19815520 MGI:4366185 NCBI chr13:12,284,312...12,355,613
Ensembl chr13:12,284,312...12,355,641 		JBrowse link
G Alpk2 alpha-kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:65,398,600...65,526,959
Ensembl chr18:65,398,600...65,527,137 		JBrowse link
G Alpk3 alpha-kinase 3 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (MGI:6201960|PMID:21873635)
(MGI:5644402|PMID:21441111)		 GO_Central
MGI		 PMID:21441111 PMID:21873635 MGI:5644402 MGI:6201960 NCBI chr 7:80,707,321...80,755,360
Ensembl chr 7:80,707,348...80,755,360 		JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 involved_in IMP (MGI:6718235|PMID:29374072) UniProt PMID:29374072 MGI:6718235 NCBI chr12:103,287,401...103,322,260
Ensembl chr12:103,287,401...103,322,260 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within IMP (MGI:3711608|PMID:17450150) MGI PMID:17450150 MGI:3711608 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within IMP (MGI:3849772|PMID:19535499) MGI PMID:19535499 MGI:3849772 NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833 		JBrowse link
G Cxadr coxsackie virus and adenovirus receptor acts_upstream_of_or_within IMP (MGI:3587448|PMID:16079292) MGI PMID:16079292 MGI:3587448 NCBI chr16:78,098,114...78,156,673
Ensembl chr16:78,098,377...78,156,662 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III acts_upstream_of_or_within IMP (MGI:3774881|PMID:18256189) MGI PMID:18256189 MGI:3774881 NCBI chr12:104,653,999...104,718,227
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within IMP (MGI:3711360|PMID:17322895) MGI PMID:17322895 MGI:3711360 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U acts_upstream_of_or_within IMP (MGI:5648096|PMID:26039991) MGI PMID:26039991 MGI:5648096 NCBI chr 1:178,148,673...178,170,063
Ensembl chr 1:178,148,673...178,165,362 		JBrowse link
G Lrrc10 leucine rich repeat containing 10 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (MGI:6201960|PMID:21873635)
(MGI:5484795|PMID:23236519)		 GO_Central
MGI		 PMID:21873635 PMID:23236519 MGI:5484795 MGI:6201960 NCBI chr10:116,881,246...116,882,673
Ensembl chr10:116,881,246...116,882,673 		JBrowse link
G Met met proto-oncogene acts_upstream_of_or_within IMP (MGI:5529574|PMID:23994610) MGI PMID:23994610 MGI:5529574 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979 		JBrowse link
G Mir208a microRNA 208a acts_upstream_of_or_within IMP (MGI:3708230|PMID:17379774) MGI PMID:17379774 MGI:3708230 NCBI chr14:55,186,517...55,186,599
Ensembl chr14:55,186,517...55,186,599 		JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within IMP (MGI:5632243|PMID:25139234) MGI PMID:25139234 MGI:5632243 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Myh11 myosin, heavy polypeptide 11, smooth muscle involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:14,012,391...14,110,052
Ensembl chr16:14,012,399...14,109,236 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha acts_upstream_of_or_within IMP (MGI:83539|PMID:8878443)
(MGI:3526615|PMID:15001446)
(MGI:1327483|PMID:9884344), (MGI:1333559|PMID:10066683)		 MGI PMID:8878443 PMID:9884344 PMID:10066683 PMID:15001446 MGI:1327483 MGI:1333559 MGI:3526615 MGI:83539 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384 		JBrowse link
G Myo18b myosin XVIIIb acts_upstream_of_or_within IMP (MGI:3821523|PMID:18761673) MGI PMID:18761673 MGI:3821523 NCBI chr 5:112,836,742...113,044,311
Ensembl chr 5:112,836,742...113,044,228 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IMP (MGI:3836832|PMID:19166829), (MGI:5285465|PMID:21640717) BHF-UCL PMID:19166829 PMID:21640717 MGI:3836832 MGI:5285465 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Plec plectin involved_in IMP (MGI:1350765|PMID:9389647) MGI PMID:9389647 MGI:1350765 NCBI chr15:76,055,174...76,115,578
Ensembl chr15:76,055,174...76,116,774 		JBrowse link
G Sgcb sarcoglycan, beta (dystrophin-associated glycoprotein) acts_upstream_of_or_within IMP (MGI:1352919|PMID:10678176) MGI PMID:10678176 MGI:1352919 NCBI chr 5:73,790,092...73,805,080
Ensembl chr 5:73,790,092...73,805,133 		JBrowse link
G Sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) acts_upstream_of_or_within IMP (MGI:5790783|PMID:23695275) MGI PMID:23695275 MGI:5790783 NCBI chr11:46,861,904...47,880,309
Ensembl chr11:46,787,080...47,879,796 		JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 involved_in
acts_upstream_of_or_within		 IMP (MGI:1927695|PMID:10967099)
(MGI:4867054|PMID:21302256)		 BHF-UCL
MGI		 PMID:10967099 PMID:21302256 MGI:1927695 MGI:4867054 NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806 		JBrowse link
G Speg SPEG complex locus acts_upstream_of_or_within IMP (MGI:4830240|PMID:19118250) MGI PMID:19118250 MGI:4830240 NCBI chr 1:75,351,941...75,408,964
Ensembl chr 1:75,351,941...75,408,964 		JBrowse link
G Tcap titin-cap involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:98,274,637...98,275,779
Ensembl chr11:98,274,637...98,275,779 		JBrowse link
G Ttn titin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:76,534,324...76,812,901
Ensembl chr 2:76,534,324...76,812,891 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within IMP (MGI:1339868|PMID:10229225) MGI PMID:10229225 MGI:1339868 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Xirp1 xin actin-binding repeat containing 1 acts_upstream_of_or_within IMP (MGI:3775114|PMID:17766470) MGI PMID:17766470 MGI:3775114 NCBI chr 9:119,842,821...119,852,664
Ensembl chr 9:119,842,821...119,852,664 		JBrowse link
G Zmpste24 zinc metallopeptidase, STE24 acts_upstream_of_or_within IMP (MGI:2178865|PMID:11923874) MGI PMID:11923874 MGI:2178865 NCBI chr 4:120,916,434...120,955,452
Ensembl chr 4:120,916,434...120,955,438 		JBrowse link
cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor, type 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169 		JBrowse link
G AW551984 expressed sequence AW551984 acts_upstream_of_or_within IGI (MGI:5295932|PMID:21554246) MGI PMID:21554246 MGI:5295932 NCBI chr 9:39,498,692...39,516,070
Ensembl chr 9:39,498,692...39,515,699 		JBrowse link
G Tbx3 T-box 3 acts_upstream_of_or_within IMP (MGI:3847383|PMID:18467625) MGI PMID:18467625 MGI:3847383 NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789 		JBrowse link
G Wnt3a wingless-type MMTV integration site family, member 3A acts_upstream_of_or_within IGI (MGI:5295932|PMID:21554246) MGI PMID:21554246 MGI:5295932 NCBI chr11:59,138,862...59,181,577
Ensembl chr11:59,138,859...59,181,578 		JBrowse link
G Wt1 WT1 transcription factor involved_in IMP (MGI:5285454|PMID:21654746) BHF-UCL PMID:21654746 MGI:5285454 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961 		JBrowse link
cardiac muscle thin filament assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neb nebulin involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:52,026,652...52,228,810
Ensembl chr 2:52,026,659...52,268,486 		JBrowse link
G Nebl nebulette involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 2:17,347,484...17,740,634
Ensembl chr 2:17,348,720...17,736,275 		JBrowse link
G Nrap nebulin-related anchoring protein involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr19:56,308,469...56,378,540
Ensembl chr19:56,308,467...56,378,469 		JBrowse link
cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin, alpha, cardiac muscle 1 acts_upstream_of_or_within IMP (MGI:87509|PMID:9114002) MGI PMID:9114002 MGI:87509 NCBI chr 2:113,877,763...113,883,356
Ensembl chr 2:113,877,763...113,884,029 		JBrowse link
G Cavin4 caveolae associated 4 acts_upstream_of_or_within ISO (MGI:3794929|PMID:18332105) MGI PMID:18332105 MGI:3794929 NCBI chr 4:48,663,514...48,673,492
Ensembl chr 4:48,663,514...48,673,502 		JBrowse link
G Csrp3 cysteine and glycine-rich protein 3 involved_in IMP (MGI:2447926|PMID:12507422) BHF-UCL PMID:12507422 MGI:2447926 NCBI chr 7:48,480,146...48,497,799
Ensembl chr 7:48,480,146...48,497,781 		JBrowse link
G Fhod3 formin homology 2 domain containing 3 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (MGI:6201960|PMID:21873635)
(MGI:5436289|PMID:23213483)		 GO_Central
MGI		 PMID:21873635 PMID:23213483 MGI:5436289 MGI:6201960 NCBI chr18:24,841,445...25,266,564
Ensembl chr18:24,841,680...25,266,558 		JBrowse link
G Myh10 myosin, heavy polypeptide 10, non-muscle acts_upstream_of_or_within IMP (MGI:1099556|PMID:9356462) MGI PMID:9356462 MGI:1099556 NCBI chr11:68,581,228...68,707,451
Ensembl chr11:68,582,385...68,707,458 		JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow acts_upstream_of_or_within IMP (MGI:1194431|PMID:9422794) MGI PMID:9422794 MGI:1194431 NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI		 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 NCBI chr 8:86,050,933...86,112,969
Ensembl chr 8:86,050,932...86,112,974 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide involved_in IGI (MGI:1931346|PMID:11239463) UniProt PMID:11239463 MGI:1931346 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide involved_in IGI (MGI:1931346|PMID:11239463) UniProt PMID:11239463 MGI:1931346 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within IMP (MGI:3513738|PMID:15569937) MGI PMID:15569937 MGI:3513738 NCBI chr17:46,857,764...46,869,194
Ensembl chr17:46,859,255...46,867,101 		JBrowse link
G Tcap titin-cap involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:98,274,637...98,275,779
Ensembl chr11:98,274,637...98,275,779 		JBrowse link
G Ttn titin involved_in
acts_upstream_of_or_within		 ISO
IMP		 (MGI:3653555|PMID:16702235) MGI PMID:16702235 GO_REF:0000096 MGI:3653555 MGI:4834177 NCBI chr 2:76,534,324...76,812,901
Ensembl chr 2:76,534,324...76,812,891 		JBrowse link
cardiac pacemaker cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shox2 short stature homeobox 2 involved_in IMP (MGI:3836832|PMID:19166829) BHF-UCL PMID:19166829 MGI:3836832 NCBI chr 3:66,879,056...66,889,104
Ensembl chr 3:66,879,060...66,889,104 		JBrowse link
cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenergic receptor, alpha 1a acts_upstream_of_or_within IGI (MGI:2664013|PMID:12782680) MGI PMID:12782680 MGI:2664013 NCBI chr14:66,872,700...67,008,689
Ensembl chr14:66,872,700...67,008,617 		JBrowse link
G Adra1b adrenergic receptor, alpha 1b acts_upstream_of_or_within IGI (MGI:2664013|PMID:12782680) MGI PMID:12782680 MGI:2664013 NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037 		JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) involved_in ISO RGD
MGI		 PMID:21376054 GO_REF:0000096 MGI:4417868 RGD:5129173 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO RGD
MGI		 PMID:21173078 GO_REF:0000096 MGI:4417868 RGD:6903878 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Akap13 A kinase (PRKA) anchor protein 13 involved_in ISO RGD
MGI		 PMID:18951085 GO_REF:0000096 MGI:4417868 RGD:2312638 NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357 		JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 acts_upstream_of_or_within IDA (MGI:5920524|PMID:29065170) MGI PMID:29065170 MGI:5920524 NCBI chr14:51,432,943...51,433,380
Ensembl chr14:51,432,781...51,436,605 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II, delta involved_in ISO RGD
MGI		 PMID:21554860 GO_REF:0000096 MGI:4417868 RGD:6907064 NCBI chr 3:126,389,136...126,639,975
Ensembl chr 3:126,389,951...126,639,975 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO RGD
MGI		 PMID:20971938 GO_REF:0000096 MGI:4417868 RGD:5131529 NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO RGD
MGI		 PMID:27854077 GO_REF:0000096 MGI:4417868 RGD:13792737 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 involved_in ISO RGD
MGI		 PMID:9769323 GO_REF:0000096 MGI:4417868 RGD:7495831 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123 		JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow ISO RGD PMID:7657802 RGD:1580138 NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535 		JBrowse link
G Myocd myocardin involved_in ISO RGD
MGI		 PMID:18772130 GO_REF:0000096 MGI:4417868 RGD:5132877 NCBI chr11:65,064,434...65,160,815
Ensembl chr11:65,067,387...65,160,815 		JBrowse link
G Nppa natriuretic peptide type A ISO RGD PMID:7657802 RGD:1580138 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nppb natriuretic peptide type B ISO RGD PMID:7657802 RGD:1580138 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 3:141,945,346...142,101,480
Ensembl chr 3:141,945,351...142,101,457 		JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I ISO RGD PMID:19542178 RGD:7775063 NCBI chr19:30,541,887...31,742,667
Ensembl chr19:30,541,889...31,742,433 		JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 8:45,960,470...46,280,943
Ensembl chr 8:45,960,825...46,280,943 		JBrowse link
His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 Iroquois related homeobox 3 involved_in IMP (MGI:6101691|PMID:26786475) BHF-UCL PMID:26786475 MGI:6101691 NCBI chr 8:92,525,139...92,528,282
Ensembl chr 8:92,525,153...92,528,695 		JBrowse link
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065 		JBrowse link
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Ccnd2 cyclin D2 involved_in ISO RGD
MGI		 PMID:27302109 GO_REF:0000096 MGI:4417868 RGD:151660350 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IMP (MGI:5902683|PMID:18371447) BHF-UCL PMID:18371447 MGI:5902683 NCBI chr17:15,587,616...15,597,275
Ensembl chr17:15,587,616...15,597,134 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:116,905,330...116,984,442
Ensembl chr10:116,905,332...116,984,439 		JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:59,521,306...59,526,114
Ensembl chr 1:59,521,583...59,526,114 		JBrowse link
G Hdac3 histone deacetylase 3 acts_upstream_of_or_within IMP (MGI:5571645|PMID:24565863) MGI PMID:24565863 MGI:5571645 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069 		JBrowse link
G Sox6 SRY (sex determining region Y)-box 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:115,070,107...115,639,186
Ensembl chr 7:115,070,107...115,638,031 		JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IMP (MGI:3689643|PMID:16151019) BHF-UCL PMID:16151019 MGI:3689643 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO RGD
MGI		 PMID:21170593 GO_REF:0000096 MGI:4417868 RGD:6784534 NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833 		JBrowse link
G Ctdp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 involved_in ISO RGD
MGI		 PMID:22569295 GO_REF:0000096 MGI:4417868 RGD:9686371 NCBI chr18:80,451,174...80,522,959
Ensembl chr18:80,451,174...80,512,910 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO RGD
MGI		 PMID:26333362 GO_REF:0000096 MGI:4417868 RGD:11561912 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682 		JBrowse link
G G6pd2 glucose-6-phosphate dehydrogenase 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 5:61,966,186...61,967,820
Ensembl chr 5:61,966,159...61,968,506 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked involved_in ISO RGD
MGI		 PMID:24190878 GO_REF:0000096 MGI:4417868 RGD:10449133 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IMP (MGI:4829580|PMID:20516643) BHF-UCL PMID:20516643 MGI:4829580 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276 		JBrowse link
G Mir451a microRNA 451a ISO RGD PMID:25209900 RGD:11558015 NCBI chr11:77,963,996...77,964,067
Ensembl chr11:77,963,996...77,964,067 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in ISO RGD
MGI		 PMID:22082674 GO_REF:0000096 MGI:4417868 RGD:11533929 NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588 		JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within ISO
IDA		 (MGI:3810223|PMID:17909105) MGI PMID:17909105 MGI:3810223 NCBI chr17:29,537,770...29,547,876
Ensembl chr17:29,536,654...29,549,567 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO RGD
MGI		 PMID:22198280 GO_REF:0000096 MGI:4417868 RGD:5687133 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Rbm10 RNA binding motif protein 10 ISO RGD PMID:30257214 RGD:151667449 NCBI chr  X:20,483,596...20,517,128
Ensembl chr  X:20,483,742...20,517,140 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO RGD
MGI		 PMID:16380388 GO_REF:0000096 MGI:4417868 RGD:13524577 NCBI chr 1:143,875,076...143,879,887
Ensembl chr 1:143,875,076...143,879,899 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 involved_in ISO RGD
MGI		 PMID:9918533 GO_REF:0000096 MGI:4417868 RGD:7207376 NCBI chr 1:169,569,046...169,575,211
Ensembl chr 1:169,569,046...169,575,211 		JBrowse link
G Tomm70a translocase of outer mitochondrial membrane 70A involved_in ISO RGD
MGI		 PMID:25022898 GO_REF:0000096 MGI:4417868 RGD:13464131 NCBI chr16:56,942,077...56,974,893
Ensembl chr16:56,942,066...56,977,068 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO RGD
MGI		 PMID:18632988 GO_REF:0000096 MGI:4417868 RGD:9588273 NCBI chr12:108,758,841...108,786,074
Ensembl chr12:108,758,899...108,786,074 		JBrowse link
G Zfp418 zinc finger protein 418 acts_upstream_of_or_within IDA
IMP		 (MGI:5920524|PMID:29065170) MGI PMID:29065170 MGI:5920524 NCBI chr 7:7,174,352...7,186,559
Ensembl chr 7:7,174,329...7,186,561 		JBrowse link
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within IMP (MGI:5432296|PMID:22711842) MGI PMID:22711842 MGI:5432296 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
positive regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in IDA (MGI:5784966|PMID:24974728) BHF-UCL PMID:24974728 MGI:5784966 NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654 		JBrowse link
G Efnb2 ephrin B2 involved_in IMP (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IMP (MGI:5784966|PMID:24974728) BHF-UCL PMID:24974728 MGI:5784966 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Kat2a K(lysine) acetyltransferase 2A involved_in ISO RGD
MGI		 PMID:20835911 GO_REF:0000096 MGI:4417868 RGD:8693751 NCBI chr11:100,595,572...100,604,427
Ensembl chr11:100,595,572...100,603,291 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO
IMP		 (MGI:3830899|PMID:16680724) MGI
UniProt		 PMID:16680724 GO_REF:0000096 MGI:3830899 MGI:4834177 NCBI chr13:83,652,136...83,815,198
Ensembl chr13:83,652,153...83,815,199 		JBrowse link
G Mir1a-1 microRNA 1a-1 involved_in ISO (PMID:20081117), (PMID:23939491) BHF-UCL PMID:20081117 PMID:23939491 NCBI chr 2:180,030,841...180,030,917
Ensembl chr 2:180,030,841...180,030,917 		JBrowse link
G Mir1a-2 microRNA 1a-2 involved_in ISO (PMID:20081117), (PMID:23939491) BHF-UCL PMID:20081117 PMID:23939491 NCBI chr18:10,785,481...10,785,552
Ensembl chr18:10,785,481...10,785,552 		JBrowse link
G Mir204 microRNA 204 involved_in ISO (PMID:22982025) BHF-UCL PMID:22982025 NCBI chr19:22,727,969...22,728,036
Ensembl chr19:22,727,969...22,728,036 		JBrowse link
G Mir499 microRNA 499 involved_in ISO (PMID:20081117) BHF-UCL PMID:20081117 NCBI chr 2:155,464,800...155,464,878
Ensembl chr 2:155,464,800...155,464,878 		JBrowse link
G Myocd myocardin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:65,064,434...65,160,815
Ensembl chr11:65,067,387...65,160,815 		JBrowse link
G Nrg1 neuregulin 1 involved_in IMP (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Wnt3a wingless-type MMTV integration site family, member 3A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:59,138,862...59,181,577
Ensembl chr11:59,138,859...59,181,578 		JBrowse link
positive regulation of cardiac muscle fiber development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenergic receptor, beta 1 involved_in ISO RGD
MGI		 PMID:18194989 GO_REF:0000096 MGI:4417868 RGD:5129139 NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545 		JBrowse link
G Akap6 A kinase (PRKA) anchor protein 6 involved_in ISO RGD
MGI		 PMID:16306226 PMID:21550986 GO_REF:0000096 MGI:4417868 RGD:2312613 RGD:6902940 NCBI chr12:52,745,371...53,202,351
Ensembl chr12:52,746,166...53,202,382 		JBrowse link
G Ccn4 cellular communication network factor 4 involved_in ISO RGD
MGI		 PMID:21376054 GO_REF:0000096 MGI:4417868 RGD:5129173 NCBI chr15:66,763,218...66,795,054
Ensembl chr15:66,763,169...66,795,050 		JBrowse link
G Ddx39b DEAD box helicase 39b involved_in ISO RGD
MGI		 PMID:20116367 GO_REF:0000096 MGI:4417868 RGD:10401141 NCBI chr17:35,460,722...35,472,683
Ensembl chr17:35,460,722...35,472,683 		JBrowse link
G Edn1 endothelin 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:12724418 RGD:2312280 NCBI chr15:81,470,329...81,536,278
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Fdps farnesyl diphosphate synthetase involved_in ISO RGD
MGI		 PMID:19716825 GO_REF:0000096 MGI:4417868 RGD:2316294 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO RGD
MGI		 PMID:24424338 GO_REF:0000096 MGI:4417868 RGD:11041632 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457 		JBrowse link
G Hamp2 hepcidin antimicrobial peptide 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 7:30,621,797...30,623,606
Ensembl chr 7:30,621,797...30,624,106 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Mir19a microRNA 19a involved_in ISO (PMID:24117217) BHF-UCL PMID:24117217 NCBI chr14:115,281,432...115,281,513
Ensembl chr14:115,281,432...115,281,513 		JBrowse link
G Mir19b-1 microRNA 19b-1 involved_in ISO (PMID:24117217) BHF-UCL PMID:24117217 NCBI chr14:115,281,737...115,281,823
Ensembl chr14:115,281,737...115,281,823 		JBrowse link
G Mir19b-2 microRNA 19b-2 involved_in ISO (PMID:24117217) BHF-UCL PMID:24117217 NCBI chr  X:51,830,860...51,830,943
Ensembl chr  X:51,830,860...51,830,943 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO RGD
MGI		 PMID:21318349 PMID:21933187 GO_REF:0000096 MGI:4417868 RGD:10040977 RGD:10040978 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in ISO RGD
MGI		 PMID:22989630 GO_REF:0000096 MGI:4417868 RGD:7174736 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase family, member 2 involved_in ISO RGD
MGI		 PMID:23261455 GO_REF:0000096 MGI:4417868 RGD:13514044 NCBI chr14:51,045,347...51,058,758
Ensembl chr14:51,045,298...51,058,758 		JBrowse link
G Pin1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO RGD
MGI		 PMID:23487407 GO_REF:0000096 MGI:4417868 RGD:8693424 NCBI chr 9:20,563,335...20,575,008
Ensembl chr 9:20,563,391...20,577,880 		JBrowse link
G Pin1rt1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1, retrogene 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:104,544,232...104,546,707
Ensembl chr 2:104,544,271...104,546,724 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO RGD
MGI		 PMID:25281201 GO_REF:0000096 MGI:4417868 RGD:13514043 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 involved_in ISO RGD
MGI		 PMID:21325829 GO_REF:0000096 MGI:4417868 RGD:9681466 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 involved_in ISO RGD
MGI		 PMID:23915320 GO_REF:0000096 MGI:4417868 RGD:11535145 NCBI chr17:57,540,227...57,570,697
Ensembl chr17:57,556,455...57,570,665 		JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within IMP (MGI:3785685|PMID:17250822) MGI PMID:17250822 MGI:3785685 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col14a1 collagen, type XIV, alpha 1 acts_upstream_of_or_within IMP (MGI:5444801|PMID:22906538) MGI PMID:22906538 MGI:5444801 NCBI chr15:55,171,040...55,384,199
Ensembl chr15:55,171,146...55,384,199 		JBrowse link
sinoatrial node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bves blood vessel epicardial substance acts_upstream_of_or_within IMP (MGI:5424322|PMID:22354168) MGI PMID:22354168 MGI:5424322 NCBI chr10:45,211,783...45,248,580
Ensembl chr10:45,211,868...45,248,575 		JBrowse link
G Isl1 ISL1 transcription factor, LIM/homeodomain involved_in IMP (MGI:5688210|PMID:26193633) BHF-UCL PMID:26193633 MGI:5688210 NCBI chr13:116,434,806...116,446,224
Ensembl chr13:116,434,817...116,446,225 		JBrowse link
G Popdc2 popeye domain containing 2 acts_upstream_of_or_within IMP (MGI:5424322|PMID:22354168) MGI PMID:22354168 MGI:5424322 NCBI chr16:38,182,523...38,198,578
Ensembl chr16:38,182,571...38,198,578 		JBrowse link
G Shox2 short stature homeobox 2 involved_in IMP (MGI:5285465|PMID:21640717) BHF-UCL PMID:21640717 MGI:5285465 NCBI chr 3:66,879,056...66,889,104
Ensembl chr 3:66,879,060...66,889,104 		JBrowse link
G Tbx18 T-box18 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:87,584,853...87,613,313
Ensembl chr 9:87,584,853...87,613,313 		JBrowse link
G Tbx3 T-box 3 acts_upstream_of_or_within
involved_in		 IMP
ISO		 (MGI:4366226|PMID:19096026) MGI PMID:19096026 GO_REF:0000096 MGI:4366226 MGI:4834177 NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789 		JBrowse link
sinoatrial node cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:79,441,989...79,443,338
Ensembl chr 7:79,441,989...79,443,536 		JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box18 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:87,584,853...87,613,313
Ensembl chr 9:87,584,853...87,613,313 		JBrowse link
ventricular cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 acts_upstream_of_or_within IMP (MGI:3711608|PMID:17450150) MGI PMID:17450150 MGI:3711608 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IDA (MGI:3695247|PMID:16798733) BHF-UCL PMID:16798733 MGI:3695247 NCBI chr 6:87,405,976...87,411,494
Ensembl chr 6:87,405,976...87,414,659 		JBrowse link
G Ccnb1 cyclin B1 ISO RGD PMID:15253691 RGD:2301353 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 ISO RGD PMID:15253691 RGD:2301353 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768 		JBrowse link
G Fhl2 four and a half LIM domains 2 acts_upstream_of_or_within IEP (PMID:15509787) BHF-UCL PMID:15509787 NCBI chr 1:43,162,231...43,237,503
Ensembl chr 1:43,162,234...43,236,144 		JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 involved_in IMP (MGI:3784153|PMID:17332425) BHF-UCL PMID:17332425 MGI:3784153 NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797 		JBrowse link
G Lmna lamin A acts_upstream_of_or_within IMP (MGI:3027329|PMID:14755333) MGI PMID:14755333 MGI:3027329 NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263 		JBrowse link
G Myh10 myosin, heavy polypeptide 10, non-muscle acts_upstream_of_or_within IMP (MGI:3052228|PMID:12893741) MGI PMID:12893741 MGI:3052228 NCBI chr11:68,581,228...68,707,451
Ensembl chr11:68,582,385...68,707,458 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in TAS (MGI:1267297|PMID:9621431) BHF-UCL PMID:9621431 MGI:1267297 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Nkx2-6 NK2 homeobox 6 acts_upstream_of_or_within IEP (PMID:9621431) BHF-UCL PMID:9621431 NCBI chr14:69,409,251...69,412,989
Ensembl chr14:69,409,251...69,412,967 		JBrowse link
G Pitx2 paired-like homeodomain transcription factor 2 acts_upstream_of_or_within IMP (MGI:3841866|PMID:18292603) MGI PMID:18292603 MGI:3841866 NCBI chr 3:128,993,527...129,013,243
Ensembl chr 3:128,993,527...129,013,240 		JBrowse link
ventricular cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C involved_in IMP (MGI:3830899|PMID:16680724) UniProt PMID:16680724 MGI:3830899 NCBI chr13:83,652,136...83,815,198
Ensembl chr13:83,652,153...83,815,199 		JBrowse link
G Myocd myocardin acts_upstream_of_or_within IMP (MGI:4941650|PMID:21357509) MGI PMID:21357509 MGI:4941650 NCBI chr11:65,064,434...65,160,815
Ensembl chr11:65,067,387...65,160,815 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within IMP (MGI:1101382|PMID:9428411) MGI PMID:9428411 MGI:1101382 NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within IMP (MGI:1101382|PMID:9428411) MGI PMID:9428411 MGI:1101382 NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924 		JBrowse link
G Rxra retinoid X receptor alpha acts_upstream_of_or_within IGI
IMP		 (MGI:1101382|PMID:9428411) MGI PMID:9428411 MGI:1101382 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Rxrb retinoid X receptor beta acts_upstream_of_or_within IMP
IGI		 (MGI:1101382|PMID:9428411) MGI PMID:9428411 MGI:1101382 NCBI chr17:34,250,786...34,257,377
Ensembl chr17:34,250,786...34,257,373 		JBrowse link
ventricular cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2A involved_in IMP (MGI:2429350|PMID:12379849) UniProt PMID:12379849 MGI:2429350 NCBI chr 7:66,880,911...67,026,435
Ensembl chr 7:66,880,911...67,022,606 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within IMP (MGI:4355491|PMID:19546853) MGI PMID:19546853 MGI:4355491 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Prox1 prospero homeobox 1 involved_in IMP (MGI:3830437|PMID:19091769) BHF-UCL PMID:19091769 MGI:3830437 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28749
    cellular process 17698
      cellular developmental process 4867
        cell differentiation 4843
          cardiocyte differentiation 217
            cardiac muscle cell differentiation 171
              His-Purkinje system cell differentiation + 4
              atrial cardiac muscle cell differentiation + 3
              cardiac muscle cell development + 115
              cardiac muscle cell fate commitment + 11
              cardiac pacemaker cell differentiation + 11
              negative regulation of cardiac muscle cell differentiation + 9
              positive regulation of cardiac muscle cell differentiation + 14
              regulation of cardiac muscle cell differentiation + 23
              ventricular cardiac muscle cell differentiation + 20
Path 2
Term Annotations click to browse term
  biological_process 28749
    developmental process 7255
      anatomical structure development 6681
        multicellular organism development 5634
          system development 5123
            circulatory system development 1387
              heart development 732
                cardiac muscle tissue development 298
                  cardiac muscle cell differentiation 171
                    His-Purkinje system cell differentiation + 4
                    atrial cardiac muscle cell differentiation + 3
                    cardiac muscle cell development + 115
                    cardiac muscle cell fate commitment + 11
                    cardiac pacemaker cell differentiation + 11
                    negative regulation of cardiac muscle cell differentiation + 9
                    positive regulation of cardiac muscle cell differentiation + 14
                    regulation of cardiac muscle cell differentiation + 23
                    ventricular cardiac muscle cell differentiation + 20
paths to the root