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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac myofibril assembly
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Accession:GO:0055003 term browser browse the term
Definition:The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
Synonyms:exact_synonym: cardiac myofibril development;   cardiac myofibril morphogenesis
 related_synonym: heart myofibril assembly


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cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin, alpha, cardiac muscle 1 acts_upstream_of_or_within ISO MGI:2180072 (MGI:87509|PMID:9114002) RGD PMID:9114002 MGI:87509 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:2447926|PMID:12507422)
Ensembl
RGD
PMID:12507422 GO_REF:0000107 MGI:2447926 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Fhod3 formin homology 2 domain containing 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5440613 (MGI:5436289|PMID:23213483)
RGD PMID:23213483, PMID:21873635 MGI:5436289, RGD:13792537 NCBI chr18:16,650,786...17,332,209
Ensembl chr18:16,650,806...17,332,210
JBrowse link
G Myh10 myosin heavy chain 10 acts_upstream_of_or_within ISO MGI:2386445 (MGI:1099556|PMID:9356462) RGD PMID:9356462 MGI:1099556 NCBI chr10:55,274,910...55,406,738
Ensembl chr10:55,275,411...55,406,732
JBrowse link
G Myl2 myosin light chain 2 acts_upstream_of_or_within ISO MGI:2385922 (MGI:1194431|PMID:9422794) RGD PMID:9422794 MGI:1194431 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IMP
IBA
PMID:17885681
PMID:21873635
BHF-UCL
GO_Central
PMID:17885681, PMID:21873635 RGD:8554371, RGD:13792537 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in IEA
ISO
ISS
GO_REF:0000107
UniProtKB:P05622 (MGI:1931346|PMID:11239463)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11239463 GO_REF:0000024 GO_REF:0000107 MGI:1931346 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO
GO_REF:0000024
UniProtKB:P26618 (MGI:1931346|PMID:11239463)
UniProt
RGD
PMID:11239463 GO_REF:0000024 MGI:1931346 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:3522206|MGI:3522214 (MGI:3513738|PMID:15569937) RGD PMID:15569937 MGI:3513738 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Tcap titin-cap involved_in ISO
IBA
(PMID:9817758)
PMID:21873635
RGD PMID:9817758, PMID:21873635 RGD:13792537 NCBI chr10:86,337,705...86,338,414
Ensembl chr10:86,337,728...86,338,411
JBrowse link
G Ttn titin involved_in
acts_upstream_of_or_within
ISO (PMID:11846417), (PMID:9817758)
MGI:3654306 (MGI:3653555|PMID:16702235)
RGD PMID:9817758 PMID:11846417 PMID:16702235 MGI:3653555 NCBI chr 3:63,565,160...63,837,815 JBrowse link
cardiac muscle thin filament assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neb nebulin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:37,658,081...37,855,843
Ensembl chr 3:37,658,563...37,854,561
JBrowse link
G Nebl nebulette involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:11822876), (PMID:18823973)
UniProt
RGD
PMID:11822876 PMID:18823973, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601
JBrowse link
G Nrap nebulin-related anchoring protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:277,104,519...277,181,397
Ensembl chr 1:277,104,514...277,181,414
JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3689643|PMID:16151019)
Ensembl
RGD
PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
ventricular cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a involved_in IEA
ISO
GO_REF:0000107
(MGI:2429350|PMID:12379849)
Ensembl
RGD
PMID:12379849 GO_REF:0000107 MGI:2429350 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (MGI:4355491|PMID:19546853)
Ensembl
RGD
PMID:19546853 GO_REF:0000107 MGI:4355491 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:3830437 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    developmental process 6765
      anatomical structure formation involved in morphogenesis 1223
        cellular component assembly involved in morphogenesis 122
          myofibril assembly 70
            cardiac myofibril assembly 18
              atrial cardiac myofibril assembly 0
              cardiac muscle myosin thick filament assembly 0
              cardiac muscle thin filament assembly 3
              negative regulation of cardiac myofibril assembly 1
              positive regulation of cardiac myofibril assembly 0
              regulation of cardiac myofibril assembly + 1
              ventricular cardiac myofibril assembly 3
Path 2
Term Annotations click to browse term
  biological_process 19491
    developmental process 6765
      anatomical structure development 6191
        multicellular organism development 5628
          system development 5300
            animal organ development 4060
              heart development 695
                cardiac muscle tissue development 260
                  cardiac muscle cell differentiation 150
                    cardiac muscle cell development 107
                      cardiac myofibril assembly 18
                        atrial cardiac myofibril assembly 0
                        cardiac muscle myosin thick filament assembly 0
                        cardiac muscle thin filament assembly 3
                        negative regulation of cardiac myofibril assembly 1
                        positive regulation of cardiac myofibril assembly 0
                        regulation of cardiac myofibril assembly + 1
                        ventricular cardiac myofibril assembly 3
paths to the root