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ONTOLOGY REPORT - ANNOTATIONS


Term:imidazole-containing compound metabolic process
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Accession:GO:0052803 term browser browse the term
Definition:The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.
Synonyms:exact_synonym: imidazole metabolism


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histamine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(PMID:22767596)
GO_REF:0000107
MGI:MGI:2182618 (MGI:MGI:2138019|PMID:11478947)
UniProt
RGD
Ensembl
PMID:11478947, PMID:22767596, PMID:21873635 GO_REF:0000041, GO_REF:0000107, MGI:MGI:2138019, RGD:13792537 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 ISO (PMID:10318872) RGD PMID:10318872 NCBI chr 3:72,395,194...72,401,254
Ensembl chr 3:72,395,218...72,401,318
JBrowse link
histamine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase ISO
ISS
(PMID:26206890)
GO_REF:0000024
RGD
UniProt
PMID:26206890 GO_REF:0000024 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
histamine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase IDA RGD PMID:4449071, PMID:9525922, PMID:7075603, PMID:5898 RGD:2303726, RGD:2303735, RGD:2303728, RGD:2303727 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hnmt histamine N-methyltransferase ISO (PMID:23505051) RGD PMID:23505051 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Trh thyrotropin releasing hormone IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:17760865, PMID:21873635 RGD:7241067, RGD:13792537 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
histidine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
JBrowse link
histidine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:34,362,635...34,406,282
Ensembl chr 7:34,361,633...34,406,318
JBrowse link
G Hal histidine ammonia lyase ISO
IBA
(MGI:MGI:52899|PMID:8486363)
PMID:21873635
RGD PMID:8486363, PMID:21873635 MGI:MGI:52899, RGD:13792537 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hdc histidine decarboxylase ISO
IBA
IEA
(MGI:MGI:2138019|PMID:11478947)
PMID:21873635
(PMID:22767596)
GO_REF:0000107
RGD
Ensembl
PMID:11478947, PMID:22767596, PMID:21873635 GO_REF:0000107, MGI:MGI:2138019, RGD:13792537 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Uroc1 urocanate hydratase 1 ISO
IBA
(PMID:19304569)
PMID:21873635
RGD PMID:19304569, PMID:21873635 RGD:13792537 NCBI chr 4:122,244,744...122,276,357
Ensembl chr 4:122,244,711...122,276,361
JBrowse link
histidine catabolic process to glutamate and formamide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:34,362,635...34,406,282
Ensembl chr 7:34,361,633...34,406,318
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,806,957...12,820,466
Ensembl chr20:12,806,957...12,820,466
JBrowse link
G Hal histidine ammonia lyase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Uroc1 urocanate hydratase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:122,244,744...122,276,357
Ensembl chr 4:122,244,711...122,276,361
JBrowse link
histidine catabolic process to glutamate and formate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:34,362,635...34,406,282
Ensembl chr 7:34,361,633...34,406,318
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,806,957...12,820,466
Ensembl chr20:12,806,957...12,820,466
JBrowse link
G Hal histidine ammonia lyase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Uroc1 urocanate hydratase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:122,244,744...122,276,357
Ensembl chr 4:122,244,711...122,276,361
JBrowse link
histidine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hal histidine ammonia lyase TAS RGD PMID:12376330 RGD:628345 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hdc histidine decarboxylase IDA RGD PMID:4449071, PMID:9525922, PMID:12204113, PMID:14622303, PMID:7075603, PMID:5898 RGD:2303726, RGD:2303735, RGD:2303734, RGD:2303733, RGD:2303728, RGD:2303727 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        cellular aromatic compound metabolic process 5708
          imidazole-containing compound metabolic process 10
            histamine metabolic process + 4
            histidine metabolic process + 7
            imidazole-containing compound catabolic process + 6
            iprodione metabolic process 0
            nitroimidazole metabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.