The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).
Synonyms:
exact_synonym:
hercynine biosynthesis from histidine; histidine betaine biosynthesis from histidine; histidine catabolic process to hercynine; histidine catabolism to N-alpha,N-alpha,N-alpha-trimethyl-L-histidine; histidine catabolism to hercynine