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ONTOLOGY REPORT - ANNOTATIONS

Term:xenobiotic glucuronidation
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Accession:GO:0052697 term browser browse the term
Definition:The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion.
Synonyms:narrow_synonym: phase II metabolism


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xenobiotic glucuronidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 involved_in ISO
IDA
IEA		 (PMID:15472229), (PMID:18719240), (PMID:19830808), (PMID:20056724) RGD
UniProt
Ensembl		 PMID:8806713 PMID:15472229 PMID:18719240 PMID:19830808 PMID:20056724 GO_REF:0000107 RGD:10769352 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 involved_in IDA (PMID:20056724) BHF-UCL PMID:20056724 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300 		JBrowse link
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 involved_in IDA (PMID:20056724) BHF-UCL PMID:20056724 NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300 		JBrowse link
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 involved_in IDA (PMID:20056724) BHF-UCL PMID:20056724 NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 involved_in IDA (PMID:20056724) BHF-UCL PMID:20056724 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
G UGT2B11 UDP glucuronosyltransferase family 2 member B11 involved_in IDA (PMID:8333863) UniProt PMID:8333863 NCBI chr 4:69,199,951...69,224,984
Ensembl chr 4:69,199,951...69,214,748 		JBrowse link
G UGT2B28 UDP glucuronosyltransferase family 2 member B28 involved_in IDA (PMID:11300766) UniProt PMID:11300766 NCBI chr 4:69,280,475...69,295,050
Ensembl chr 4:69,280,475...69,295,050 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    cellular process 18460
      cellular metabolic process 11168
        xenobiotic metabolic process 143
          xenobiotic glucuronidation 7
Path 2
Term Annotations click to browse term
  biological_process 19770
    metabolic process 12509
      cellular metabolic process 11168
        organic acid metabolic process 1059
          oxoacid metabolic process 1049
            carboxylic acid metabolic process 1022
              monocarboxylic acid metabolic process 720
                uronic acid metabolic process 26
                  glucuronate metabolic process 26
                    cellular glucuronidation 21
                      xenobiotic glucuronidation 7
paths to the root