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ONTOLOGY REPORT - ANNOTATIONS

Term:cyclic purine nucleotide metabolic process
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Accession:GO:0052652 term browser browse the term
Definition:The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine.
Synonyms:exact_synonym: cyclic purine nucleotide metabolism


show annotations for term's descendants           Sort by:
cyclic purine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd2 adenosine monophosphate deaminase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23911318)		 UniProt
RGD		 PMID:23911318 GO_REF:0000024 NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271 		JBrowse link
cAMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:14985420 GO_REF:0000033, RGD:2312640 NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969 		JBrowse link
G Adcy10 adenylate cyclase 10 involved_in IDA
ISO
IMP		 (PMID:12609998), (PMID:15659711) RGD PMID:12609998 PMID:15659711 PMID:9874775 PMID:7225326 PMID:16627466 More... RGD:1299450, RGD:2313177, RGD:2313173, RGD:2313171 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Adcy2 adenylate cyclase 2 involved_in IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000117
PMID:18164588
PMID:10427002		 GO_Central
UniProt
RGD		 PMID:11738086 PMID:18164588 PMID:10427002 PMID:12711600 GO_REF:0000033 GO_REF:0000117, RGD:2312641, RGD:8553431, RGD:10400857, RGD:2312674 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236 		JBrowse link
G Adcy3 adenylate cyclase 3 involved_in IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000117
(MGI:1889935|PMID:11055432)
PMID:24363043		 GO_Central
UniProt
RGD		 PMID:11055432 PMID:12711600 PMID:24363043 GO_REF:0000033 GO_REF:0000117 MGI:1889935, RGD:2312674, RGD:10400870 NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686 		JBrowse link
G Adcy4 adenylate cyclase 4 involved_in IDA
IEA
IBA		 PMID:8900209
GO_REF:0000117
GO_REF:0000033		 UniProt
GO_Central
RGD		 PMID:11738086 PMID:12711600 PMID:8900209 GO_REF:0000033 GO_REF:0000117, RGD:2312641, RGD:2312674, RGD:8554340 NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108 		JBrowse link
G Adcy5 adenylate cyclase 5 involved_in IDA
ISO
IBA
IEA		 (PMID:8119955), (PMID:9748257)
GO_REF:0000033
GO_REF:0000117
(PMID:15385642), (PMID:24700542), (PMID:24740569)		 RGD
GO_Central
UniProt		 PMID:8119955 PMID:9748257 PMID:15385642 PMID:24700542 PMID:24740569 More... GO_REF:0000033 GO_REF:0000117, RGD:2312641, RGD:2315006, RGD:2312674 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adcy6 adenylate cyclase 6 involved_in IDA
IMP
ISO
IEA
IBA		 (PMID:17916776), (PMID:18403039)
(MGI:4457984|PMID:20466003)
GO_REF:0000117
GO_REF:0000033
(PMID:8119955)		 RGD
UniProt
GO_Central		 PMID:8119955 PMID:17916776 PMID:18403039 PMID:20466003 PMID:15961389 More... GO_REF:0000033 GO_REF:0000117 MGI:4457984, RGD:1598749, RGD:2312641, RGD:2312654, RGD:2312678, RGD:2312674, RGD:2313211, RGD:2315006 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754 		JBrowse link
G Adcy7 adenylate cyclase 7 involved_in IDA
IBA
ISO		 GO_REF:0000033
(PMID:11113152), (PMID:17760784)		 GO_Central
RGD		 PMID:11113152 PMID:17760784 PMID:12711600 GO_REF:0000033, RGD:2312674 NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311 		JBrowse link
G Adcy8 adenylate cyclase 8 involved_in IMP
IEA
IBA		 GO_REF:0000117
GO_REF:0000033		 UniProt
GO_Central
RGD		 PMID:16741924 PMID:19444869 PMID:19305019 GO_REF:0000033 GO_REF:0000117, RGD:2312769, RGD:2312785, RGD:7241269 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Adcy9 adenylate cyclase 9 acts_upstream_of_or_within
involved_in		 IMP
ISO		 (PMID:7575502), (PMID:8662814)
(PMID:10987815), (PMID:9628827)		 RGD PMID:7575502 PMID:8662814 PMID:9628827 PMID:10987815 PMID:19444869 RGD:2312785 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:11278900 RGD:10003101 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11278900 RGD:10003101 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
cAMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde10a phosphodiesterase 10A involved_in IDA
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:10583409 GO_REF:0000041, RGD:68285 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563 		JBrowse link
G Pde4a phosphodiesterase 4A involved_in IEA
ISO
IDA		 GO_REF:0000041
(MGI:1927461|PMID:11267656)
PMID:21323643
(PMID:18095939)
(PMID:9677330)
(PMID:7888306)
(PMID:11306681)
PMID:8557632		 UniProt
RGD		 PMID:7888306 PMID:9677330 PMID:11267656 PMID:11306681 PMID:18095939 More... GO_REF:0000041 MGI:1927461, RGD:151356649, RGD:633604 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde4c phosphodiesterase 4C involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:18,690,727...18,711,555
Ensembl chr16:18,691,700...18,710,640 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pde7a phosphodiesterase 7A involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:101,714,767...101,806,853
Ensembl chr 2:101,718,444...101,806,681 		JBrowse link
G Pde8a phosphodiesterase 8A involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024 		JBrowse link
G Pde8b phosphodiesterase 8B involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209 		JBrowse link
cAMP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO MGI:1856936 (PMID:7595494) RGD PMID:7595494 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:27385333) RGD PMID:27385333 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:11130725 RGD:151708734 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
cGMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:23505436)
MGI:3640802 (PMID:16614755)
GO_REF:0000033
GO_REF:0000002		 RGD
GO_Central
InterPro		 PMID:16614755 PMID:23505436 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671 		JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 involved_in ISO
IBA		 (PMID:23505436)
GO_REF:0000033		 RGD
GO_Central		 PMID:23505436 GO_REF:0000033 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 involved_in IEA GO_REF:0000002
GO_REF:0000043		 InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441 		JBrowse link
G Gucy2c guanylate cyclase 2C involved_in IEA
IBA		 GO_REF:0000043
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000043 NCBI chr 4:169,568,505...169,649,092
Ensembl chr 4:169,568,529...169,649,092 		JBrowse link
G Gucy2d guanylate cyclase 2D involved_in IDA
IBA
IEA		 PMID:11580282
GO_REF:0000033
GO_REF:0000043		 GO_Central
UniProt		 PMID:11580282 GO_REF:0000033 GO_REF:0000043, RGD:15023466 NCBI chr 1:152,739,775...152,774,474
Ensembl chr 1:152,739,775...152,774,473 		JBrowse link
G Gucy2e guanylate cyclase 2E involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(MGI:5049799|PMID:21598940)		 Ensembl
GO_Central
RGD		 PMID:21598940 GO_REF:0000033 GO_REF:0000107 MGI:5049799 NCBI chr10:53,954,918...53,975,576
Ensembl chr10:53,959,010...53,974,067 		JBrowse link
G Gucy2f guanylate cyclase 2F involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:105,710,356...105,808,183
Ensembl chr  X:105,710,356...105,808,183 		JBrowse link
G Gucy2g guanylate cyclase 2G involved_in IEA
IBA		 GO_REF:0000043
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000043 NCBI chr 1:254,237,778...254,280,277
Ensembl chr 1:254,239,174...254,280,277 		JBrowse link
G Nppa natriuretic peptide A acts_upstream_of
involved_in		 ISO
IBA
IEA
IMP		 (PMID:1672777)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:1672777 PMID:10559136 GO_REF:0000033 GO_REF:0000107, RGD:619660 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nppb natriuretic peptide B acts_upstream_of
involved_in		 ISO
IBA		 (PMID:1672777)
GO_REF:0000033		 RGD
GO_Central		 PMID:1672777 GO_REF:0000033 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nppc natriuretic peptide C acts_upstream_of
involved_in		 ISO
IBA		 (PMID:1672777)
GO_REF:0000033
(MGI:2177134|PMID:11259675)		 RGD
GO_Central		 PMID:1672777 PMID:11259675 GO_REF:0000033 MGI:2177134 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Npr1 natriuretic peptide receptor 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:1672777)
GO_REF:0000033
MGI:2386604 (MGI:2179542|PMID:11997476)
GO_REF:0000043		 RGD
GO_Central
UniProt		 PMID:1672777 PMID:11997476 GO_REF:0000033 GO_REF:0000043 MGI:2179542 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505 		JBrowse link
G Npr2 natriuretic peptide receptor 2 acts_upstream_of
involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:1672777)
GO_REF:0000033
(MGI:2682104|PMID:14514678)
GO_REF:0000107
GO_REF:0000043		 RGD
GO_Central
Ensembl
UniProt		 PMID:1672777 PMID:14514678 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 MGI:2682104 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
cGMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde10a phosphodiesterase 10A involved_in IDA
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:10583409 GO_REF:0000041, RGD:68285 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563 		JBrowse link
G Pde1a phosphodiesterase 1A IMP RGD PMID:16514069 RGD:2312521 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO
IBA
IEA		 (PMID:19828435)
GO_REF:0000033
(MGI:4420377|PMID:19632989)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:19632989 PMID:19828435 GO_REF:0000033 GO_REF:0000107 MGI:4420377 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde5a phosphodiesterase 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000041
(PMID:12554648)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:12554648 GO_REF:0000041 GO_REF:0000107 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000041
(MGI:1266874|PMID:9624145), (MGI:5634842|PMID:25799991)
(PMID:25799991)		 UniProt
GO_Central
RGD		 PMID:9624145 PMID:25799991 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 MGI:1266874 MGI:5634842 NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948 		JBrowse link
cGMP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857092 (PMID:3038581), (PMID:7518067) RGD PMID:3038581 PMID:7518067 NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in ISO MGI:1856702 (PMID:15722353) RGD PMID:15722353 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
G Pde5a phosphodiesterase 5A acts_upstream_of_or_within ISO (PMID:19474061), (PMID:20511540) RGD PMID:19474061 PMID:20511540 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISO
ISS		 (PMID:9624146)
GO_REF:0000024		 RGD
UniProt		 PMID:9624146 GO_REF:0000024 NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948 		JBrowse link
G Rora RAR-related orphan receptor A acts_upstream_of_or_within ISO MGI:1857035 (PMID:7518067) RGD PMID:7518067 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      purine-containing compound metabolic process 594
        purine nucleotide metabolic process 560
          cyclic purine nucleotide metabolic process 44
            3',5'-cyclic diguanylic acid metabolic process 0
            cAMP metabolic process + 23
            cGMP metabolic process + 21
Path 2
Term Annotations click to browse term
  biological_process 20115
    cellular process 18524
      cellular metabolic process 10293
        phosphorus metabolic process 2742
          organophosphate metabolic process 1060
            nucleoside phosphate metabolic process 627
              nucleotide metabolic process 617
                cyclic nucleotide metabolic process 45
                  cyclic purine nucleotide metabolic process 44
                    3',5'-cyclic diguanylic acid metabolic process 0
                    cAMP metabolic process + 23
                    cGMP metabolic process + 21
paths to the root