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ONTOLOGY REPORT - ANNOTATIONS


Term:tRNA dimethylallyltransferase activity
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Accession:GO:0052381 term browser browse the term
Definition:Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.
Comment:Note that this activity was formerly know in GO and EC as 'tRNA isopentenyltransferase' (GO:0004811), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate.
Synonyms:exact_synonym: dimethylallyl-diphosphate:tRNA dimethylallyltransferase activity
 broad_synonym: tRNA prenyltransferase activity
 related_synonym: tRNA isopentenyltransferase activity
 alt_id: GO:0004811
 xref: EC:2.5.1.75;   MetaCyc:RXN0-6274;   RHEA:26482;   reactome:R-HSA-6784462 "TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs";   reactome:R-HSA-6787567 "TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser)"



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tRNA dimethylallyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trit1 tRNA isopentenyltransferase 1 enables ISO
IBA
(PMID:24901367), (PMID:34774131)
(PMID:24126054)
GO_REF:0000033
(PMID:23289710)
RGD
GO_Central
PMID:23289710 PMID:24126054 PMID:24901367 PMID:34774131 GO_REF:0000033 NCBI chr 5:140,578,459...140,623,881
Ensembl chr 5:135,295,330...135,338,764
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Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      transferase activity 2444
        transferase activity, transferring alkyl or aryl (other than methyl) groups 78
          tRNA dimethylallyltransferase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      catalytic activity, acting on a nucleic acid 632
        catalytic activity, acting on RNA 391
          catalytic activity, acting on a tRNA 136
            tRNA dimethylallyltransferase activity 1
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