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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of telomerase activity
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Accession:GO:0051973 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Synonyms:exact_synonym: up regulation of telomerase activity;   upregulation of telomerase activity
 narrow_synonym: activation of telomerase activity;   stimulation of telomerase activity
 related_synonym: telomerase activator



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positive regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IBA
(PMID:17237768)
PMID:21873635
RGD PMID:17237768 PMID:21873635 RGD:13792537 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461
JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of ISO (MGI:5428344|PMID:22723415) RGD PMID:22723415 MGI:5428344 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:25467444)
MGI:3849598 (MGI:3047190|PMID:15240872)
RGD PMID:15240872 PMID:25467444 MGI:3047190
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:16545136) RGD PMID:16545136 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Grhl2 grainyhead-like transcription factor 2 involved_in ISO (PMID:19015635), (PMID:20938050) RGD PMID:19015635 PMID:20938050 NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258
JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO (PMID:23685356) RGD PMID:23685356 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Klf4 Kruppel like factor 4 involved_in ISO (PMID:20629177) RGD PMID:20629177 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358
JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in ISO
IEA
(PMID:21531765)
GO_REF:0000107
RGD
Ensembl
PMID:21531765 GO_REF:0000107 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645
JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:5810267|PMID:9637678) RGD PMID:9637678 MGI:5810267 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein involved_in ISO (PMID:27510903) RGD PMID:27510903 NCBI chr16:22,837,586...22,868,293
Ensembl chr16:22,837,588...22,868,293
JBrowse link
G Nek2 NIMA-related kinase 2 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nek7 NIMA-related kinase 7 involved_in IEA
ISO
IBA
GO_REF:0000107
(PMID:21531765)
PMID:21873635
Ensembl
RGD
PMID:21531765 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
JBrowse link
G Nvl nuclear VCP-like involved_in ISO
IBA
(PMID:22226966)
PMID:21873635
RGD PMID:22226966 PMID:21873635 RGD:13792537 NCBI chr13:92,851,023...92,906,749
Ensembl chr13:92,853,650...92,906,049
JBrowse link
G Parm1 prostate androgen-regulated mucin-like protein 1 involved_in IMP
IBA
PMID:12772192
PMID:21873635
UniProt
GO_Central
PMID:12772192 PMID:21873635 RGD:8553456, RGD:13792537 NCBI chr14:16,468,309...16,577,339
Ensembl chr14:16,468,459...16,577,314
JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878) RGD PMID:26482878 NCBI chr10:1,410,636...1,548,573
Ensembl chr10:1,410,642...1,548,560
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920
JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:15181449), (PMID:16043710), (PMID:17237768) RGD PMID:15181449 PMID:16043710 PMID:17237768 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
JBrowse link
G Prkcq protein kinase C, theta involved_in ISO
IEA
(PMID:21531765)
GO_REF:0000107
RGD
Ensembl
PMID:21531765 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO (PMID:10197982), (PMID:19740745)
(MGI:5819359|PMID:10197982)
RGD PMID:10197982 PMID:19740745 MGI:5819359 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Tcp1 t-complex 1 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Tnks tankyrase involved_in ISO (PMID:12782650) RGD PMID:12782650 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO
GO_REF:0000024
(PMID:19179534), (PMID:23685356), (PMID:25467444), (PMID:29804836)
(MGI:6189679|PMID:29804836)
UniProt
RGD
PMID:19179534 PMID:23685356 PMID:25467444 PMID:29804836 GO_REF:0000024 MGI:6189679 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    biological regulation 13380
      regulation of molecular function 3136
        positive regulation of molecular function 1606
          positive regulation of catalytic activity 1169
            positive regulation of transferase activity 592
              positive regulation of telomerase activity 33
Path 2
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      cellular metabolic process 9831
        cellular aromatic compound metabolic process 5651
          nucleobase-containing compound metabolic process 5422
            nucleic acid metabolic process 4890
              DNA metabolic process 999
                regulation of DNA metabolic process 521
                  regulation of DNA biosynthetic process 136
                    regulation of telomerase activity 52
                      positive regulation of telomerase activity 33
paths to the root