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ONTOLOGY REPORT - ANNOTATIONS


Term:methotrexate transport
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Accession:GO:0051958 term browser browse the term
Definition:The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.



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methotrexate transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a1 solute carrier family 19 member 1 involved_in IDA
ISO
PMID:10827155
(MGI:1303207|PMID:9748272)
(PMID:22554803)
RGD PMID:9748272 PMID:22554803 PMID:10827155 MGI:1303207, RGD:14929207 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
JBrowse link
G Slc46a1 solute carrier family 46 member 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    localization 5475
      establishment of localization 4825
        transport 4663
          organic substance transport 2480
            organic acid transport 353
              methotrexate transport 2
Path 2
Term Annotations click to browse term
  biological_process 18737
    localization 5475
      establishment of localization 4825
        transport 4663
          ion transport 1667
            anion transport 533
              organic anion transport 388
                carboxylic acid transport 315
                  dicarboxylic acid transport 103
                    methotrexate transport 2
paths to the root