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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of protein kinase B signaling
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Accession:GO:0051897 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
Synonyms:exact_synonym: positive regulation of AKT signalling cascade;   positive regulation of PKB signaling cascade
 narrow_synonym: activation of protein kinase B signaling cascade;   stimulation of protein kinase B signaling cascade
 related_synonym: positive regulation of AKT signaling cascade;   positive regulation of PKB signalling cascade;   positive regulation of protein kinase B signaling cascade;   positive regulation of protein kinase B signalling cascade;   up regulation of protein kinase B signaling cascade;   upregulation of protein kinase B signaling cascade



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positive regulation of protein kinase B signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009349|PMID:20683884) RGD PMID:20683884 MGI:5009349 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 involved_in ISO (PMID:18508192) RGD PMID:18508192 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:18508192) RGD PMID:18508192 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Angpt1 angiopoietin 1 involved_in ISO
IEA
(PMID:18425120), (PMID:19615361)
GO_REF:0000107
RGD
Ensembl
PMID:18425120 PMID:19615361 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 involved_in IMP PMID:24090963 CACAO PMID:24090963 RGD:10047159 NCBI chr 5:8,982,061...9,076,326
Ensembl chr 5:8,981,540...9,076,326
JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP
ISO
(MGI:3690676|PMID:16051150) RGD PMID:16051150 PMID:19171933 MGI:3690676, RGD:5510006 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Axl Axl receptor tyrosine kinase involved_in IBA
ISO
PMID:21873635
(MGI:5315346|PMID:16723520)
RGD PMID:16723520 PMID:21873635 MGI:5315346, RGD:13792537 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bag4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) RGD PMID:21712384 MGI:5292318 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G C1qbp complement C1q binding protein involved_in ISS
ISO
GO_REF:0000024
(PMID:16177118)
UniProt
RGD
PMID:16177118 GO_REF:0000024 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C1qtnf1 C1q and TNF related 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3829513|PMID:18783346)
GO_REF:0000107
RGD
Ensembl
PMID:18783346 GO_REF:0000107 MGI:3829513 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G C1qtnf12 C1q and TNF related 12 acts_upstream_of_or_within ISO (MGI:5317500|PMID:22275362) RGD PMID:22275362 MGI:5317500 NCBI chr 5:166,551,628...166,556,003
Ensembl chr 5:166,551,628...166,556,003
JBrowse link
G C1qtnf3 C1q and TNF related 3 acts_upstream_of_or_within ISO (MGI:4868567|PMID:20952387) RGD PMID:20952387 MGI:4868567 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
JBrowse link
G Calcr calcitonin receptor involved_in ISO ComplexPortal:CPX-1134|UniProtKB:O60896|UniProtKB:P10997:PRO_0000004106 (PMID:22500019) RGD PMID:22500019 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392
JBrowse link
G Cass4 Cas scaffold protein family member 4 involved_in ISO (PMID:27677288) RGD PMID:27677288 NCBI chr 3:161,162,520...161,202,523
Ensembl chr 3:161,163,436...161,202,186
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15059845), (PMID:15778365) RGD PMID:15059845 PMID:15778365 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:15059845), (PMID:15778365) RGD PMID:15059845 PMID:15778365 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO (MGI:5520006|PMID:23589618) RGD PMID:23589618 MGI:5520006 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Chi3l1 chitinase 3 like 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:21385870)
(MGI:5306542|PMID:21546314)
UniProt
RGD
PMID:21385870 PMID:21546314 GO_REF:0000024 MGI:5306542 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Cpne1 copine 1 involved_in ISO (PMID:23263657), (PMID:25450385) RGD PMID:23263657 PMID:25450385 NCBI chr 3:144,587,548...144,629,603
Ensembl chr 3:144,588,995...144,598,636
JBrowse link
G Csf3 colony stimulating factor 3 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IMP
IEA
UniProtKB:P35411 (PMID:10415068), (PMID:10869418)
PMID:12729461
GO_REF:0000107
RGD
Ensembl
PMID:10415068 PMID:10869418 PMID:12729461 GO_REF:0000107, RGD:13673777 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 acts_upstream_of_or_within ISO MGI:1341264 (MGI:5507957|PMID:22956548) RGD PMID:22956548 MGI:5507957 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Egf epidermal growth factor involved_in ISO
IEA
(PMID:31915155)
GO_REF:0000107
RGD
Ensembl
PMID:31915155 GO_REF:0000107 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:17655843) RGD PMID:17655843 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eng endoglin involved_in ISO RNAcentral:URS00005A8080_9606 (PMID:26857067) RGD PMID:26857067 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G F10 coagulation factor X involved_in IEA
ISO
GO_REF:0000107
(PMID:18612547)
Ensembl
RGD
PMID:18612547 GO_REF:0000107 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F3 coagulation factor III, tissue factor involved_in ISO (PMID:18612547) RGD PMID:18612547 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G F7 coagulation factor VII involved_in ISO (PMID:18612547) RGD PMID:18612547 NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Fam110c family with sequence similarity 110, member C involved_in ISO
ISS
(PMID:19698782)
GO_REF:0000024
RGD
UniProt
PMID:19698782 GO_REF:0000024 NCBI chr 6:47,638,466...47,644,723
Ensembl chr 6:47,638,276...47,644,634
JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:24226523) RGD PMID:24226523 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in
acts_upstream_of_or_within
ISO (PMID:26451614), (PMID:31915155)
(MGI:3701731|PMID:16858399)
RGD PMID:16858399 PMID:26451614 PMID:31915155 MGI:3701731 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 involved_in ISO RNAcentral:URS000058BB84_9606|UniProtKB:P09038 (PMID:26451614) RGD PMID:26451614 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO
IDA
(PMID:16359517), (PMID:16723520), (PMID:18680538)
PMID:18374201
RGD PMID:16359517 PMID:16723520 PMID:18680538 PMID:18374201 RGD:8554638 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gata3 GATA binding protein 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:19674970)
UniProt
RGD
PMID:19674970 GO_REF:0000024 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 involved_in ISO (PMID:21750175)
(MGI:5545971|PMID:21750175)
RGD PMID:21750175 MGI:5545971 NCBI chr17:23,796,859...23,901,625
NCBI chr17:23,866,602...23,868,691
Ensembl chr17:23,796,859...23,901,611
JBrowse link
G Gdf15 growth differentiation factor 15 involved_in ISO
ISS
IEA
(PMID:28846097), (PMID:28846099)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:28846097 PMID:28846099 GO_REF:0000024 GO_REF:0000107 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gfral GDNF family receptor alpha like involved_in ISO (PMID:28846097) RGD PMID:28846097 NCBI chr 8:76,917,894...76,963,349
Ensembl chr 8:76,918,657...76,959,425
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:19717735 RGD:4892081 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2158814 (MGI:3613414|PMID:15663476)
Ensembl
RGD
PMID:15663476 GO_REF:0000107 MGI:3613414 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G H19 H19 imprinted maternally expressed transcript acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Hax1 HCLS1 associated protein X-1 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in ISO (PMID:17655843) RGD PMID:17655843 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014
JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:21874357 RGD:150540304 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hpse heparanase involved_in IEA
ISO
GO_REF:0000107
(PMID:15044433)
(MGI:3721153|PMID:17689495)
Ensembl
RGD
PMID:15044433 PMID:17689495 GO_REF:0000107 MGI:3721153 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (MGI:6148478|PMID:24286867) RGD PMID:24286867 MGI:6148478 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO (MGI:6148478|PMID:24286867) RGD PMID:24286867 MGI:6148478 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Iapp islet amyloid polypeptide involved_in ISO ComplexPortal:CPX-3187|UniProtKB:O60896|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr 4:175,237,013...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (MGI:3837587|PMID:19208758) RGD PMID:19208758 MGI:3837587 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2386328 (MGI:3789406|PMID:18451178)
RGD PMID:18451178 PMID:21873635 MGI:3789406, RGD:13792537 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 involved_in ISO (PMID:11500939) RGD PMID:11500939 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 acts_upstream_of_or_within ISO (MGI:3806392|PMID:18762576) RGD PMID:18762576 MGI:3806392 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il18 interleukin 18 involved_in ISO
IEA
(PMID:21321938)
GO_REF:0000107
RGD
Ensembl
PMID:21321938 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il6 interleukin 6 IDA RGD PMID:20227492 RGD:5128677 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilk integrin-linked kinase IMP RGD PMID:16941698 RGD:2302063 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:11500939), (PMID:25240198) RGD PMID:11500939 PMID:25240198 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Insr insulin receptor involved_in IBA
ISO
PMID:21873635
(PMID:11500939)
RGD PMID:11500939 PMID:21873635 RGD:13792537 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO (PMID:24044949) RGD PMID:24044949 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037
JBrowse link
G Itsn1 intersectin 1 acts_upstream_of_or_within ISO (MGI:3768571|PMID:17875942) RGD PMID:17875942 MGI:3768571 NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645
JBrowse link
G Lep leptin involved_in ISS
ISO
GO_REF:0000024
(MGI:5700303|PMID:16825198)
UniProt
RGD
PMID:16825198 GO_REF:0000024 MGI:5700303 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lin28a lin-28 homolog A involved_in ISO (MGI:5294254|PMID:21962509) RGD PMID:21962509 MGI:5294254 NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122
JBrowse link
G LOC259246 alpha-2u globulin PGCL1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 Ensembl chr 5:75,142,157...75,564,845 JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISO UniProtKB:P05067:PRO_0000000092 (PMID:27241555) RGD PMID:27241555 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408
JBrowse link
G Mc1r melanocortin 1 receptor involved_in ISO (MGI:4412441|PMID:18292087) RGD PMID:18292087 MGI:4412441 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within ISO (MGI:4848231|PMID:21059917) RGD PMID:21059917 MGI:4848231 NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:29168081) RGD PMID:29168081 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743
JBrowse link
G Mir126b microRNA 126b involved_in ISO (PMID:28578351) RGD PMID:28578351 NCBI chr 3:9,415,087...9,415,159 JBrowse link
G Mir132 microRNA 132 involved_in ISO (PMID:21868695) RGD PMID:21868695 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796
JBrowse link
G Mir205 microRNA 205 acts_upstream_of_or_within ISO (MGI:5514438|PMID:23974039) RGD PMID:23974039 MGI:5514438 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:16762633), (PMID:22879939), (PMID:24983504) RGD PMID:16762633 PMID:22879939 PMID:24983504 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:19962668) RGD PMID:19962668 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mir29a microRNA 29a involved_in ISO (PMID:21573166), (PMID:23426367) RGD PMID:21573166 PMID:23426367 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir494 microRNA 494 acts_upstream_of_or_within ISO (MGI:5302482|PMID:20837890) RGD PMID:20837890 MGI:5302482 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358
JBrowse link
G Mst1r macrophage stimulating 1 receptor involved_in ISO
IBA
(PMID:12676986)
PMID:21873635
RGD PMID:12676986 PMID:21873635 RGD:13792537 NCBI chr 8:108,596,100...108,611,389
Ensembl chr 8:108,597,299...108,612,455
JBrowse link
G Mtdh metadherin involved_in ISO (PMID:17704808) RGD PMID:17704808 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:17110594 RGD:2307383 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mydgf myeloid-derived growth factor involved_in ISO (MGI:5609664|PMID:25581518) RGD PMID:25581518 MGI:5609664 NCBI chr 9:999,659...1,008,895
Ensembl chr 9:1,000,722...1,008,822
JBrowse link
G Myoc myocilin involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:21656515)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21656515 GO_REF:0000024 GO_REF:0000107 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127
JBrowse link
G Myorg myogenesis regulating glycosidase acts_upstream_of_or_within ISO (MGI:4422154|PMID:19706595) RGD PMID:19706595 MGI:4422154 NCBI chr 5:56,654,257...56,664,467
Ensembl chr 5:56,648,643...56,664,440
JBrowse link
G Ngfr nerve growth factor receptor IDA RGD PMID:19457114 RGD:5508731 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) RGD PMID:17942966 MGI:5009390 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nrg1 neuregulin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4454957|PMID:20448149)
GO_REF:0000107
RGD
Ensembl
PMID:20448149 GO_REF:0000107 MGI:4454957 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (PMID:26078884) RGD PMID:26078884 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Nts neurotensin acts_upstream_of
involved_in
ISO
IEA
(PMID:21806946)
GO_REF:0000107
RGD
Ensembl
PMID:21806946 GO_REF:0000107 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 acts_upstream_of_or_within
involved_in
ISO (MGI:5289772|PMID:21441927)
(MGI:5644010|PMID:23812417)
RGD PMID:21441927 PMID:23812417 MGI:5289772 MGI:5644010 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
JBrowse link
G Osm oncostatin M involved_in ISO RNAcentral:URS0000574A2C_9606 (PMID:28972028) RGD PMID:28972028 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in IMP PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP PMID:18183622
PMID:17299767
ARUK-UCL PMID:18183622 PMID:17299767 RGD:13673786, RGD:13673751 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISS
ISO
GO_REF:0000024
(PMID:19019919)
UniProt
RGD
PMID:19019919 GO_REF:0000024 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Phb1 prohibitin 1 involved_in IMP PMID:32173312 UniProt PMID:32173312 RGD:30309944 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IMP PMID:20819118 UniProt PMID:20819118 RGD:8693633 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO UniProtKB:P15692 (PMID:30496354) RGD PMID:30496354 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in ISO (PMID:18558630) RGD PMID:18558630 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta involved_in ISO UniProtKB:P01133|UniProtKB:P09038|UniProtKB:P15692 (PMID:31915155)
(MGI:6405586|PMID:31915155)
RGD PMID:31915155 MGI:6405586 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma involved_in ISO (PMID:12507995) RGD PMID:12507995 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 involved_in ISO (PMID:12507995) RGD PMID:12507995 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (MGI:5490149|PMID:23495099) RGD PMID:23495099 MGI:5490149 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:15166238)
RNAcentral:URS000060A1F4_9606 (PMID:15166238), (PMID:26944318)
UniProt
RGD
PMID:15166238 PMID:26944318 GO_REF:0000024 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (PMID:18936167) RGD PMID:18936167 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260
JBrowse link
G Ramp3 receptor activity modifying protein 3 involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P10997:PRO_0000004106|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902
JBrowse link
G Rara retinoic acid receptor, alpha involved_in IMP PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rasd2 RASD family, member 2 involved_in IDA PMID:14724584 UniProt PMID:14724584 RGD:1304287 NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016
JBrowse link
G Ret ret proto-oncogene involved_in ISS
ISO
GO_REF:0000024
(PMID:28846097)
UniProt
RGD
PMID:28846097 GO_REF:0000024 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:17110594 PMID:21873635 RGD:2307383, RGD:13792537 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Rtn4 reticulon 4 involved_in ISO
IEA
(PMID:27353365)
GO_REF:0000107
RGD
Ensembl
PMID:27353365 GO_REF:0000107 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Sema5a semaphorin 5A involved_in ISS
ISO
GO_REF:0000024
(MGI:5526935|PMID:19850054)
UniProt
RGD
PMID:19850054 GO_REF:0000024 MGI:5526935 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO MGI:4124253 (MGI:6101898|PMID:26787558) RGD PMID:26787558 MGI:6101898 NCBI chr20:13,337,983...13,443,665
Ensembl chr20:13,339,692...13,443,665
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:18070883) RGD PMID:18070883 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104798|MGI:1929004 (MGI:4420852|PMID:20080598)
Ensembl
RGD
PMID:20080598 GO_REF:0000107 MGI:4420852 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233
JBrowse link
G Stox1 storkhead box 1 involved_in ISO (MGI:5635320|PMID:25677106) RGD PMID:25677106 MGI:5635320 NCBI chr20:30,598,656...30,666,371
Ensembl chr20:30,598,168...30,666,939
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:19386626) RGD PMID:19386626 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tek TEK receptor tyrosine kinase involved_in IBA
ISO
PMID:21873635
(PMID:18425120), (PMID:19615361)
RGD PMID:18425120 PMID:19615361 PMID:21873635 RGD:13792537 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:18625725)
GO_REF:0000024
RGD
UniProt
PMID:18625725 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:18625725) RGD PMID:18625725 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18653767) RGD PMID:18653767 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thpo thrombopoietin involved_in ISO
ISS
(PMID:15337790)
GO_REF:0000024
(MGI:5314162|PMID:22128142)
RGD
UniProt
PMID:15337790 PMID:22128142 GO_REF:0000024 MGI:5314162 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within
IMP
ISO
PMID:12729461
(MGI:4420852|PMID:20080598)
RGD PMID:20080598 PMID:12729461 MGI:4420852, RGD:13673777 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip8l3 TNF alpha induced protein 8 like 3 involved_in ISO (MGI:5613301|PMID:25242044) RGD PMID:25242044 MGI:5613301 NCBI chr 8:54,413,503...54,455,648
Ensembl chr 8:54,414,457...54,500,079
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1859962 (MGI:1889907|PMID:11051546)
GO_REF:0000107
RGD
Ensembl
PMID:11051546 GO_REF:0000107 MGI:1889907 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tpbg trophoblast glycoprotein acts_upstream_of_or_within ISO MGI:103556 (MGI:5507957|PMID:22956548) RGD PMID:22956548 MGI:5507957 NCBI chr 8:86,793,953...86,797,324
Ensembl chr 8:86,793,749...86,797,741
JBrowse link
G Tspyl5 TSPY-like 5 involved_in ISO (PMID:20079711) RGD PMID:20079711 NCBI chr 7:64,881,092...64,885,538
Ensembl chr 7:64,884,225...64,885,457
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:30496354), (PMID:31915155)
(MGI:5287519|PMID:21828096)
(PMID:31915155)
RGD PMID:21828096 PMID:30496354 PMID:31915155 MGI:5287519 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfb vascular endothelial growth factor B involved_in ISO (PMID:18259607) RGD PMID:18259607 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link
G Xbp1 X-box binding protein 1 NOT|involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    positive regulation of biological process 6780
      positive regulation of signaling 2000
        positive regulation of signal transduction 1677
          positive regulation of intracellular signal transduction 1087
            positive regulation of protein kinase B signaling 132
Path 2
Term Annotations click to browse term
  biological_process 20094
    biological regulation 13926
      regulation of biological process 13157
        regulation of cellular process 12435
          signal transduction 7105
            intracellular signal transduction 2740
              protein kinase B signaling 237
                regulation of protein kinase B signaling 203
                  positive regulation of protein kinase B signaling 132
paths to the root