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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial depolarization
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Accession:GO:0051882 term browser browse the term
Definition:The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.
Synonyms:exact_synonym: mitochondria depolarization;   mitochondrial depolarisation;   mitochondrial membrane depolarization;   mitochondrion depolarization
 only_in_taxon: NCBITaxon:2759 ! Eukaryota



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mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677
JBrowse link
G Casp1 caspase 1 acts_upstream_of_or_within ISO (PMID:23028046) RGD PMID:23028046 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:25217637) RGD PMID:25217637 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
JBrowse link
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO
IEA
MGI:2145814|MGI:2153356 (PMID:19293339), (PMID:19519726), (PMID:24852368)
GO_REF:0000107
RGD
Ensembl
PMID:19293339 PMID:19519726 PMID:24852368 GO_REF:0000107 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO (PMID:20885443) RGD PMID:20885443 NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:188,572,926...188,631,302
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within ISO
IEA
(PMID:20885443)
GO_REF:0000107
RGD
Ensembl
PMID:20885443 GO_REF:0000107 NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:99,619,544...99,914,610
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of ISO MGI:2386080 (PMID:16198349) RGD PMID:16198349 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
JBrowse link
G Ppif peptidylprolyl isomerase F acts_upstream_of_or_within ISO MGI:88459 (PMID:19293339) RGD PMID:19293339 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954
JBrowse link
negative regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16153637)
Ensembl
UniProt
RGD
PMID:16153637 GO_REF:0000024 GO_REF:0000107 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO
IEA
(PMID:27098698)
GO_REF:0000107
RGD
Ensembl
PMID:27098698 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:29215467 RGD:13504824 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
JBrowse link
G Hsh2d hematopoietic SH2 domain containing acts_upstream_of_or_within ISO
IEA
(PMID:15569688)
GO_REF:0000107
RGD
Ensembl
PMID:15569688 GO_REF:0000107 NCBI chr16:17,664,548...17,686,976
Ensembl chr16:17,669,345...17,682,013
JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:19457114 RGD:5508731 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305
JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 IMP RGD PMID:34731606 RGD:329845875 NCBI chr 7:110,691,230...110,934,901
Ensembl chr 7:110,691,230...110,934,987
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
JBrowse link
positive regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:80,284,295...80,366,926
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15564577 RGD:2313870 NCBI chr10:55,456,923...55,469,239
Ensembl chr10:55,456,928...55,469,199
JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO UniProtKB:P35968 (PMID:23798385) RGD PMID:23798385 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within ISO
IEA
UniProtKB:P07585 (PMID:23798385)
GO_REF:0000107
RGD
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISO
IEA
IBA
ISS
(PMID:18852119)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024
RGD
Ensembl
GO_Central
UniProt
PMID:18852119 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:185,484,791...185,493,961
Ensembl chr 2:185,484,793...185,493,961
JBrowse link
G Myoc myocilin involved_in ISO
IEA
ISS
(PMID:17516541)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17516541 GO_REF:0000024 GO_REF:0000107 NCBI chr13:77,509,963...77,520,361
Ensembl chr13:77,509,963...77,520,361
JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:19139380 RGD:2305938 NCBI chr 1:254,547,311...254,589,596
Ensembl chr 1:254,547,311...254,582,855
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (PMID:16198349) RGD PMID:16198349 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP protein:increased activity:brain: RGD PMID:21616968 RGD:10413888 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948
JBrowse link
G Tspo translocator protein IDA RGD PMID:15183124 RGD:2317155 NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:116,600,210...116,610,460
JBrowse link
regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISO (PMID:25583114) RGD PMID:25583114 NCBI chr  X:156,579,669...156,601,448
Ensembl chr  X:156,579,785...156,601,446
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO
IEA
MGI:104995 (PMID:15288121)
GO_REF:0000107
RGD
Ensembl
PMID:15288121 GO_REF:0000107 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO
IEA
MGI:104990 (PMID:15288121)
GO_REF:0000107
RGD
Ensembl
PMID:15288121 GO_REF:0000107 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO
IEA
(PMID:22736029)
GO_REF:0000107
RGD
Ensembl
PMID:22736029 GO_REF:0000107 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:124,706,080...124,867,239
JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma acts_upstream_of_or_within ISO
IEA
MGI:3759678 (PMID:16129705)
GO_REF:0000107
RGD
Ensembl
PMID:16129705 GO_REF:0000107 NCBI chr 6:78,382,849...78,406,037
Ensembl chr 6:78,382,855...78,406,201
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    biological regulation 13899
      regulation of biological quality 3507
        regulation of membrane potential 555
          membrane depolarization 117
            mitochondrial depolarization 31
              negative regulation of mitochondrial depolarization 7
              positive regulation of mitochondrial depolarization 11
              regulation of mitochondrial depolarization + 23
paths to the root