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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial depolarization
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Accession:GO:0051882 term browser browse the term
Definition:The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.
Synonyms:exact_synonym: mitochondria depolarization;   mitochondrial depolarisation;   mitochondrial membrane depolarization;   mitochondrion depolarization



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mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Casp1 caspase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5466421|PMID:23028046)
Ensembl
RGD
PMID:23028046 GO_REF:0000107 MGI:5466421 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:25217637) RGD PMID:25217637 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
negative regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5796062|PMID:27098698) RGD PMID:27098698 MGI:5796062 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:29215467 RGD:13504824 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Hsh2d hematopoietic SH2 domain containing acts_upstream_of_or_within ISO (MGI:3574118|PMID:15569688) RGD PMID:15569688 MGI:3574118 NCBI chr16:17,630,519...17,649,932
Ensembl chr16:17,635,322...17,647,991
JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:19457114 RGD:5508731 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
positive regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15564577 RGD:2313870 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Cck cholecystokinin IDA apoptotic RGD PMID:11964411 RGD:625521 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO UniProtKB:P35968 (PMID:23798385) RGD PMID:23798385 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within
involved_in
ISO
IEA
UniProtKB:P07585 (PMID:23798385)
GO_REF:0000107
RGD
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:18852119)
UniProt
RGD
PMID:18852119 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Myoc myocilin involved_in ISO
IEA
ISS
(PMID:17516541)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17516541 GO_REF:0000024 GO_REF:0000107 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127
JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:19139380 RGD:2305938 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (MGI:3607437|PMID:16198349) RGD PMID:16198349 MGI:3607437 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP protein:increased activity:brain: RGD PMID:21616968 RGD:10413888 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Tspo translocator protein IDA RGD PMID:15183124 RGD:2317155 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISO (MGI:5790173|PMID:25583114) RGD PMID:25583114 MGI:5790173 NCBI chr  X:151,428,334...151,450,115
Ensembl chr  X:151,428,578...151,450,115
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO MGI:104990 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:22736029) RGD PMID:22736029 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma acts_upstream_of_or_within ISO MGI:3759678 (MGI:3589325|PMID:16129705) RGD PMID:16129705 MGI:3589325 NCBI chr 6:72,647,025...72,670,885
Ensembl chr 6:72,647,025...72,672,491
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 19834
    biological regulation 13775
      regulation of biological quality 4234
        regulation of membrane potential 494
          membrane depolarization 96
            mitochondrial depolarization 24
              negative regulation of mitochondrial depolarization 5
              positive regulation of mitochondrial depolarization 11
              regulation of mitochondrial depolarization + 21
paths to the root