Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:nitric-oxide synthase biosynthetic process
go back to main search page
Accession:GO:0051767 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
Synonyms:exact_synonym: NO synthase biosynthesis;   NO synthase biosynthetic process;   NOS biosynthesis;   NOS biosynthetic process
 narrow_synonym: NOS1 biosynthesis;   NOS2 biosynthesis;   NOS2 synthase biosynthesis;   NOS2 synthase biosynthetic process;   NOS3 biosynthesis;   brain nitric-oxide synthase biosynthetic process;   endothelial nitric-oxide synthase biosynthetic process;   inducible nitric-oxide synthase biosynthetic process;   nitric-oxide synthase (type 2) biosynthesis;   nitric-oxide synthase (type 2) biosynthetic process;   nitric-oxide synthase (type II) biosynthesis;   nitric-oxide synthase (type II) biosynthetic process;   nitric-oxide synthase 2 biosynthetic process;   nitric-oxide synthase-1 biosynthetic process;   nitric-oxide synthase-3 biosynthetic process
 alt_id: GO:0051768
 never_in_taxon: NCBITaxon:4751 ! Fungi


show annotations for term's descendants           Sort by:
negative regulation of nitric-oxide synthase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 involved_in ISO (PMID:16820593) RGD PMID:16820593 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha IMP RGD PMID:9153192 RGD:2302974 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO
ISS		 (PMID:18962899)
GO_REF:0000024
(MGI:5009376|PMID:18962899), (MGI:5009411|PMID:16023107)		 RGD
BHF-UCL		 PMID:16023107 PMID:18962899 GO_REF:0000024 MGI:5009376 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Pggt1b protein geranylgeranyltransferase type I subunit beta IMP RGD PMID:9153192 RGD:2302974 NCBI chr18:38,952,147...38,995,656
Ensembl chr18:38,952,914...38,995,503 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11991626 RGD:10003093 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA		 (PMID:18675776)
GO_REF:0000107		 RGD
Ensembl		 PMID:18675776 GO_REF:0000107 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833 		JBrowse link
positive regulation of nitric-oxide synthase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap12 A-kinase anchoring protein 12 IMP RGD PMID:19937403 RGD:14348968 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 involved_in ISO (MGI:4943659|PMID:19164781) RGD PMID:19164781 MGI:4943659 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 IDA RGD PMID:19428685 RGD:7488896 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 IMP RGD PMID:21620800 RGD:9685153 NCBI chr 1:135,300,048...135,407,688
Ensembl chr 1:135,300,461...135,409,760 		JBrowse link
G Fcer2 Fc epsilon receptor II involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476 		JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha IMP RGD PMID:9153192 RGD:2302974 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460 		JBrowse link
G Fntb farnesyltransferase, CAAX box, beta IMP RGD PMID:9153192 RGD:2302974 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586 		JBrowse link
G Ifng interferon gamma involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:5776417|PMID:26227742), (MGI:6304699|PMID:29061364) RGD PMID:26227742 PMID:29061364 MGI:5776417 MGI:6304699 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:6414704|PMID:26936882)		 Ensembl
RGD		 PMID:26936882 GO_REF:0000107 MGI:6414704 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Jak2 Janus kinase 2 involved_in IDA
ISO		 PMID:11536325
UniProtKB:P01580 (MGI:5009182|PMID:12426001), (MGI:5009205|PMID:10600756), (MGI:5776417|PMID:26227742)		 RGD PMID:10600756 PMID:12426001 PMID:26227742 PMID:11536325 MGI:5009182 MGI:5009205 MGI:5776417, RGD:8553830 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jak3 Janus kinase 3 IMP RGD PMID:22788969 RGD:11533941 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Kdr kinase insert domain receptor involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:10600473), (PMID:9837777)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:9837777 PMID:10600473 GO_REF:0000024 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:22302802 RGD:13462052 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IMP RGD PMID:10593906 RGD:2304240 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IMP RGD PMID:10593906 RGD:2304240 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IMP RGD PMID:10593906 RGD:2304240 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:10593906 RGD:2304240 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in ISO (PMID:19727662) RGD PMID:19727662 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (MGI:4946442|PMID:21156799) RGD PMID:21156799 MGI:4946442 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IMP RGD PMID:22788969 RGD:11533941 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO (MGI:4456948|PMID:15356140) RGD PMID:15356140 MGI:4456948 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4456948|PMID:15356140)		 Ensembl
RGD		 PMID:15356140 GO_REF:0000107 MGI:4456948 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (MGI:4456948|PMID:15356140) RGD PMID:15356140 MGI:4456948 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      organic substance metabolic process 11752
        macromolecule metabolic process 10095
          macromolecule biosynthetic process 5168
            nitric-oxide synthase biosynthetic process 28
              negative regulation of nitric-oxide synthase biosynthetic process 6
              positive regulation of nitric-oxide synthase biosynthetic process 23
              regulation of nitric-oxide synthase biosynthetic process + 28
paths to the root