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ONTOLOGY REPORT - ANNOTATIONS

Term:cytosine C-5 DNA demethylase activity
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Accession:GO:0051747 term browser browse the term
Definition:Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.
Synonyms:exact_synonym: DNA methyltransferase activity acting on cytosine C-5
 broad_synonym: DNA demethylase activity;   hydrolytic DNA demethylase activity


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cytosine C-5 DNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase enables IDA
ISO
ISS
IBA		 (PMID:16174769) MGI
GO_Central
UniProt		 PMID:16174769 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:114,261,987...114,268,782
Ensembl chr 5:114,261,987...114,266,279 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables IDA (PMID:16174769) MGI PMID:16174769 NCBI chr 2:93,810,979...93,841,099
Ensembl chr 2:93,810,895...93,841,152 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28796
    catalytic activity 5724
      hydrolase activity 2474
        cytosine C-5 DNA demethylase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 28796
    catalytic activity 5724
      catalytic activity, acting on a nucleic acid 646
        catalytic activity, acting on DNA 326
          DNA demethylase activity 5
            cytosine C-5 DNA demethylase activity 2
paths to the root