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ONTOLOGY REPORT - ANNOTATIONS

Term:cytosine C-5 DNA demethylase activity
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Accession:GO:0051747 term browser browse the term
Definition:Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.
Synonyms:exact_synonym: DNA methyltransferase activity acting on cytosine C-5
 broad_synonym: DNA demethylase activity;   hydrolytic DNA demethylase activity


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cytosine C-5 DNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase enables IEA
IDA
IBA		 (PMID:18432238) Ensembl
UniProt
GO_Central		 PMID:18432238 GO_REF:0000033 GO_REF:0000107 NCBI chr12:109,088,189...109,093,472
Ensembl chr12:109,088,188...109,093,631 		JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase enables ISO (PMID:16174769) MGI PMID:16174769 NCBI chr11:43,880,831...43,920,274
Ensembl chr11:43,880,811...43,920,274 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19683
    catalytic activity 6023
      hydrolase activity 2644
        cytosine C-5 DNA demethylase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 19683
    catalytic activity 6023
      catalytic activity, acting on a nucleic acid 655
        catalytic activity, acting on DNA 266
          DNA demethylase activity 5
            cytosine C-5 DNA demethylase activity 2
paths to the root