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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates
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Accession:GO:0051719 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.
Synonyms:xref: Reactome:R-HSA-9845308 "DNMT3A:DNMT3L in nascent RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L methylates cytosine in DNA";   reactome:R-HSA-5334097 "DNMT3B:DNMT3L methylates cytosine in DNA";   reactome:R-HSA-5334152 "DNMT3A:DNMT3L methylates cytosine in DNA"



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DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G Dnmt3a DNA methyltransferase 3 alpha enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      catalytic activity, acting on a nucleic acid 650
        catalytic activity, acting on DNA 283
          DNA-methyltransferase activity 7
            DNA (cytosine-5-)-methyltransferase activity 5
              DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates 3
Path 2
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      transferase activity 2397
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              DNA (cytosine-5-)-methyltransferase activity 5
                DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates 3
paths to the root