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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
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Accession:GO:0051718 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).
Synonyms:narrow_synonym: HpaII methylase;   M.BsuRIa;   M.BsuRIb
 xref: reactome:R-HSA-5334151 "DNMT1 methylates cytosine in hemimethylated DNA"



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DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3b DNA methyltransferase 3 beta enables IBA
ISO
GO_REF:0000033
(PMID:27856912)
GO_Central
RGD
PMID:27856912 GO_REF:0000033 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dnmt3c DNA methyltransferase 3C enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 3:142,178,533...142,210,954 JBrowse link
G Dnmt3l DNA methyltransferase 3 like enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      catalytic activity, acting on a nucleic acid 650
        catalytic activity, acting on DNA 283
          DNA-methyltransferase activity 7
            DNA (cytosine-5-)-methyltransferase activity 5
              DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates 3
Path 2
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      transferase activity 2397
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              DNA (cytosine-5-)-methyltransferase activity 5
                DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates 3
paths to the root