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ONTOLOGY REPORT - ANNOTATIONS
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Term:
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
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Accession:
GO:0051718
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Definition:
Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).
Synonyms:
narrow_synonym:
HpaII methylase; M.BsuRIa; M.BsuRIb
xref:
reactome:R-HSA-5334151 "DNMT1 methylates cytosine in hemimethylated DNA"
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Mouse (2)
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Genes (3)
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Dnmt3b
DNA methyltransferase 3 beta
enables
IBA
ISO
GO_REF:0000033
(PMID:27856912)
GO_Central
RGD
PMID:27856912
GO_REF:0000033
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
G
Dnmt3c
DNA methyltransferase 3C
enables
IEA
GO_REF:0000107
Ensembl
GO_REF:0000107
Ensembl chr 3:142,178,533...142,210,954
G
Dnmt3l
DNA methyltransferase 3 like
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516
Term paths to the root
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Path 1
Term
Annotations
molecular_function
20634
catalytic activity
6032
catalytic activity, acting on a nucleic acid
650
catalytic activity, acting on DNA
283
DNA-methyltransferase activity
7
DNA (cytosine-5-)-methyltransferase activity
5
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
3
Path 2
Term
Annotations
molecular_function
20634
catalytic activity
6032
transferase activity
2397
transferase activity, transferring one-carbon groups
213
methyltransferase activity
203
S-adenosylmethionine-dependent methyltransferase activity
169
DNA (cytosine-5-)-methyltransferase activity
5
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
3