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ONTOLOGY REPORT - ANNOTATIONS


Term:actin filament capping
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Accession:GO:0051693 term browser browse the term
Definition:The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
Synonyms:related_synonym: F-actin capping activity;   actin capping activity



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actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVIL advillin involved_in IEA UniProt GO_REF:0000043 NCBI chr12:57,797,380...57,818,734
Ensembl chr12:57,797,376...57,818,734
JBrowse link
G CAPG capping actin protein, gelsolin like involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:85,391,602...85,419,540
Ensembl chr 2:85,394,753...85,418,432
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:112,619,832...112,671,616
Ensembl chr 1:112,619,805...112,671,616
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:116,862,587...116,922,049
Ensembl chr 7:116,811,070...116,922,049
JBrowse link
G CAPZA3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr12:18,738,119...18,739,188
Ensembl chr12:18,738,119...18,739,188
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
JBrowse link
G DMTN dematin actin binding protein involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:22,048,931...22,082,525
Ensembl chr 8:22,048,995...22,082,527
JBrowse link
G GSN gelsolin involved_in IMP
ISS
IEA
(PMID:19666531) UniProt
Ensembl
PMID:19666531 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G MYH9 myosin heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) UniProt PMID:23325791 MGI:5619440 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010
JBrowse link
G RDX radixin involved_in IEA UniProt GO_REF:0000043 NCBI chr11:110,174,922...110,296,614
Ensembl chr11:109,864,295...110,296,712
JBrowse link
G SCIN scinderin involved_in IMP
IEA
(PMID:19666531) UniProt PMID:19666531 GO_REF:0000043 NCBI chr 7:12,570,720...12,660,182
Ensembl chr 7:12,570,577...12,660,182
JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:158,610,704...158,686,715
Ensembl chr 1:158,610,704...158,686,715
JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662
JBrowse link
G SPTB spectrin beta, erythrocytic involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr14:64,746,283...64,879,907
Ensembl chr14:64,746,283...64,879,907
JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 2:54,456,327...54,671,446
Ensembl chr 2:54,456,327...54,671,446
JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr11:66,682,497...66,744,682
Ensembl chr11:66,682,497...66,744,670
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr19:40,467,001...40,576,464
Ensembl chr19:40,466,241...40,576,464
JBrowse link
G SPTBN5 spectrin beta, non-erythrocytic 5 involved_in IEA UniProt GO_REF:0000043 NCBI chr15:41,848,146...41,894,053
Ensembl chr15:41,848,146...41,894,053
JBrowse link
G TPM1 tropomyosin 1 ISO RGD PMID:15779917 RGD:1600523 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915
JBrowse link
G VIL1 villin 1 involved_in IEA
IDA
(PMID:16921170), (PMID:17182858), (PMID:19808673) UniProt PMID:16921170 PMID:17182858 PMID:19808673 GO_REF:0000043 NCBI chr 2:218,419,123...218,453,295
Ensembl chr 2:218,419,121...218,453,295
JBrowse link
G VILL villin like involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:37,987,978...38,007,185
Ensembl chr 3:37,988,059...38,007,188
JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC097637.1 novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 3:52,221,081...52,231,190 JBrowse link
G ADD1 adducin 1 involved_in IDA
IEA
IBA
(PMID:8626479) BHF-UCL
TreeGrafter
GO_Central
PMID:8626479 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076
JBrowse link
G ADD2 adducin 2 involved_in IDA
IEA
IBA
(PMID:8626479) BHF-UCL
TreeGrafter
GO_Central
PMID:8626479 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:70,656,784...70,768,200
Ensembl chr 2:70,607,618...70,768,225
JBrowse link
G ADD3 adducin 3 involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr10:109,996,373...110,135,565
Ensembl chr10:109,996,368...110,135,565
JBrowse link
G AVIL advillin involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr12:57,797,380...57,818,734
Ensembl chr12:57,797,376...57,818,734
JBrowse link
G CAPG capping actin protein, gelsolin like involved_in TAS
IBA
IEA
(PMID:1322908) PINC
GO_Central
TreeGrafter
PMID:1322908 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:85,391,602...85,419,540
Ensembl chr 2:85,394,753...85,418,432
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
(MGI:3758397|PMID:17656356) MGI
TreeGrafter
GO_Central
UniProt
InterPro
PMID:17656356 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 MGI:3758397 NCBI chr 1:112,619,832...112,671,616
Ensembl chr 1:112,619,805...112,671,616
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA
IBA
UniProt
GO_Central
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr 7:116,862,587...116,922,049
Ensembl chr 7:116,811,070...116,922,049
JBrowse link
G CAPZA3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA
IBA
InterPro
TreeGrafter
GO_Central
UniProt
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr12:18,738,119...18,739,188
Ensembl chr12:18,738,119...18,739,188
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
(MGI:3758397|PMID:17656356) MGI
TreeGrafter
GO_Central
UniProt
InterPro
PMID:17656356 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 MGI:3758397 NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
JBrowse link
G DBNL drebrin like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) MGI PMID:10637315 MGI:1353214 NCBI chr 7:44,044,702...44,069,456
Ensembl chr 7:44,044,640...44,069,456
JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329
JBrowse link
G FLII FLII actin remodeling protein involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr17:18,244,815...18,259,022
Ensembl chr17:18,244,815...18,258,738
JBrowse link
G GSN gelsolin involved_in IEA
IBA
TAS
(PMID:1321812) UniProt
GO_Central
TreeGrafter
PINC
PMID:1321812 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G RDX radixin involved_in ISO
IEA
RGD
Ensembl
PMID:2500445 GO_REF:0000107 RGD:8693627 NCBI chr11:110,174,922...110,296,614
Ensembl chr11:109,864,295...110,296,712
JBrowse link
G SCIN scinderin involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 7:12,570,720...12,660,182
Ensembl chr 7:12,570,577...12,660,182
JBrowse link
G SVIL supervillin involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr10:29,457,338...29,736,936
Ensembl chr10:29,457,338...29,736,959
JBrowse link
G TRIOBP TRIO and F-actin binding protein involved_in NAS (PMID:11148140) UniProt PMID:11148140 NCBI chr22:37,697,048...37,776,556
Ensembl chr22:37,697,048...37,776,556
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IEA
IBA
Ensembl
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:43,793,723...43,806,317
Ensembl chr12:43,793,723...43,806,328
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in ISS
IBA
IEA
(PMID:18837697) BHF-UCL
GO_Central
TreeGrafter
PMID:18837697 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:52,228,612...52,239,158
Ensembl chr 3:52,228,612...52,246,788
JBrowse link
G VIL1 villin 1 involved_in IMP
IBA
IEA
(PMID:15272027) UniProt
GO_Central
TreeGrafter
PMID:15272027 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:218,419,123...218,453,295
Ensembl chr 2:218,419,121...218,453,295
JBrowse link
G VILL villin like involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 3:37,987,978...38,007,185
Ensembl chr 3:37,988,059...38,007,188
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in ISS
IEA
CAFA
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:25,279,374...25,620,530
Ensembl chr 6:25,279,078...25,620,530
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IDA (PMID:26466680) UniProt PMID:26466680 NCBI chr16:67,645,144...67,657,569
Ensembl chr16:67,644,988...67,657,569
JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in IDA
IBA
IEA
(PMID:30361697) UniProt
GO_Central
TreeGrafter
PMID:30361697 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:56,049,098...56,330,609
Ensembl chr 4:56,049,098...56,330,609
JBrowse link
G WASHC2C WASH complex subunit 2C involved_in IDA (PMID:20498093) UniProt PMID:20498093 NCBI chr10:45,727,043...45,792,964
Ensembl chr10:45,727,200...45,792,964
JBrowse link
pointed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LMOD1 leiomodin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:201,896,456...201,946,548
Ensembl chr 1:201,896,456...201,946,548
JBrowse link
G LMOD2 leiomodin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:123,655,866...123,664,290
Ensembl chr 7:123,655,866...123,664,290
JBrowse link
G LMOD3 leiomodin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:69,106,065...69,122,595
Ensembl chr 3:69,106,065...69,123,032
JBrowse link
G TMOD1 tropomodulin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:97,501,180...97,601,743
Ensembl chr 9:97,501,180...97,601,743
JBrowse link
G TMOD2 tropomodulin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr15:51,751,597...51,816,363
Ensembl chr15:51,751,597...51,816,363
JBrowse link
G TMOD3 tropomodulin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr15:51,829,653...51,915,725
Ensembl chr15:51,829,628...51,947,295
JBrowse link
G TMOD4 tropomodulin 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:151,169,987...151,175,981
Ensembl chr 1:151,169,986...151,176,284
JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr 2:218,217,189...218,254,348
Ensembl chr 2:218,217,141...218,254,356
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD35 ankyrin repeat domain 35 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:145,866,564...145,885,866
Ensembl chr 1:145,866,560...145,885,866
JBrowse link
G ANKRD52 ankyrin repeat domain 52 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:56,237,807...56,258,384
Ensembl chr12:56,237,807...56,258,384
JBrowse link
G ANKRD55 ankyrin repeat domain 55 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:56,099,680...56,233,330
Ensembl chr 5:56,099,680...56,233,330
JBrowse link
G ANKRD61 ankyrin repeat domain 61 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:6,031,376...6,036,552
Ensembl chr 7:6,031,376...6,036,552
JBrowse link
G ASB2 ankyrin repeat and SOCS box containing 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:93,934,166...93,976,570
Ensembl chr14:93,934,166...93,976,739
JBrowse link
G MTPN myotrophin involved_in IDA
IBA
(PMID:16895918) UniProt
GO_Central
PMID:16895918 GO_REF:0000033 NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19761
    cellular process 18444
      negative regulation of cellular process 6080
        negative regulation of cellular component organization 878
          negative regulation of supramolecular fiber organization 203
            negative regulation of actin filament depolymerization 57
              actin filament capping 51
                barbed-end actin filament capping + 34
                pointed-end actin filament capping 7
Path 2
Term Annotations click to browse term
  biological_process 19761
    cellular process 18444
      cellular component organization or biogenesis 7593
        cellular component organization 7367
          organelle organization 4025
            cytoskeleton organization 1717
              actin cytoskeleton organization 831
                actin filament organization 538
                  actin polymerization or depolymerization 231
                    regulation of actin polymerization or depolymerization 186
                      regulation of actin filament depolymerization 66
                        negative regulation of actin filament depolymerization 57
                          actin filament capping 51
                            barbed-end actin filament capping + 34
                            pointed-end actin filament capping 7
paths to the root