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ONTOLOGY REPORT - ANNOTATIONS


Term:actin filament capping
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Accession:GO:0051693 term browser browse the term
Definition:The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
Synonyms:related_synonym: F-actin capping activity;   actin capping activity



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actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO (PMID:19666531)
(MGI:5619440|PMID:23325791)
RGD PMID:19666531 PMID:23325791 MGI:5619440 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Myh9 myosin, heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) RGD PMID:23325791 MGI:5619440 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Scin scinderin involved_in ISO (PMID:19666531) RGD PMID:19666531 NCBI chr 6:57,110,128...57,188,059
Ensembl chr 6:57,109,403...57,188,242
JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:86,203,504...86,279,371
Ensembl chr13:86,203,504...86,279,371
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Sptb spectrin, beta, erythrocytic involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:95,310,342...95,437,221
Ensembl chr 6:95,310,326...95,437,118
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in IEA GO_REF:0000043
GO_REF:0000104
UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228
JBrowse link
G Tpm1 tropomyosin 1 IDA RGD PMID:15779917 RGD:1600523 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Tpm1_v7 tropomyosin 1, variant 7 IDA RGD PMID:15779917 RGD:1600523
G Vil1 villin 1 involved_in ISO (PMID:16921170), (PMID:17182858), (PMID:19808673) RGD PMID:16921170 PMID:17182858 PMID:19808673 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858
JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933400A11Rik similar to RIKEN cDNA 4933400A11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:24,389,645...24,393,849 JBrowse link
G Add1 adducin 1 involved_in ISO
IBA
(PMID:8626479)
PMID:21873635
RGD PMID:8626479 PMID:21873635 RGD:13792537 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Add2 adducin 2 involved_in ISO
IEA
IBA
(PMID:8626479)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:8626479 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505
JBrowse link
G Add3 adducin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
JBrowse link
G Avil advillin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
G Capg capping actin protein, gelsolin like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3758397|PMID:17656356)
RGD PMID:17656356 PMID:21873635 MGI:3758397, RGD:13792537 NCBI chr 2:192,319,696...192,364,755
Ensembl chr 2:192,319,702...192,364,480
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
JBrowse link
G Capza3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 4:172,929,273...172,930,486
Ensembl chr 4:172,928,887...172,932,535
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000104
(MGI:3758397|PMID:17656356)
PMID:21873635
UniProt
RGD
PMID:17656356 PMID:21873635 GO_REF:0000104 MGI:3758397, RGD:13792537 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Dbnl drebrin-like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) RGD PMID:10637315 MGI:1353214 NCBI chr14:80,666,115...80,681,155
Ensembl chr14:80,666,124...80,681,155
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:4460022|PMID:20532239), (MGI:5476881|PMID:23314863), (MGI:5486559|PMID:15558031)
UniProt
RGD
PMID:15558031 PMID:20532239 PMID:23314863 GO_REF:0000024 MGI:4460022 MGI:5476881 MGI:5486559 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
JBrowse link
G Flii FLII, actin remodeling protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970
JBrowse link
G Gsn gelsolin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Rdx radixin IDA RGD PMID:2500445 RGD:8693627 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
JBrowse link
G Scin scinderin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:57,110,128...57,188,059
Ensembl chr 6:57,109,403...57,188,242
JBrowse link
G Svil supervillin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA
ISO
PMID:21873635
(MGI:3840765|PMID:18837697)
RGD PMID:18837697 PMID:21873635 MGI:3840765, RGD:13792537 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894
JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA
ISO
PMID:21873635
(MGI:3840765|PMID:18837697)
RGD PMID:18837697 PMID:21873635 MGI:3840765, RGD:13792537 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298
JBrowse link
G Vil1 villin 1 involved_in ISO
IBA
(PMID:15272027)
PMID:21873635
RGD PMID:15272027 PMID:21873635 RGD:13792537 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858
JBrowse link
G Vill villin-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:118,776,718...118,794,983
Ensembl chr 8:118,776,742...118,794,983
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO
IBA
(PMID:30361697)
PMID:21873635
RGD PMID:30361697 PMID:21873635 RGD:13792537 NCBI chr14:31,284,066...31,520,103
Ensembl chr14:31,284,184...31,522,431
JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851
JBrowse link
pointed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmod1 leiomodin 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
JBrowse link
G Lmod2 leiomodin 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120
JBrowse link
G Lmod3 leiomodin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:129,843,964...129,858,684
Ensembl chr 4:129,843,970...129,858,244
JBrowse link
G Tmod1 tropomodulin 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:60,316,445...60,393,957
Ensembl chr 5:60,338,512...60,393,956
JBrowse link
G Tmod2 tropomodulin 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720
JBrowse link
G Tmod3 tropomodulin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:76,248,978...76,310,855
Ensembl chr 8:76,248,979...76,310,977
JBrowse link
G Tmod4 tropomodulin 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:182,695,709...182,700,540
Ensembl chr 2:182,695,709...182,700,540
JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:23704350 RGD:11570555 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO
ISS
IBA
(PMID:16895918)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:16895918 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18872
    cellular process 17581
      negative regulation of cellular process 5067
        negative regulation of cellular component organization 768
          negative regulation of supramolecular fiber organization 185
            negative regulation of actin filament depolymerization 50
              actin filament capping 44
                barbed-end actin filament capping + 28
                pointed-end actin filament capping 7
Path 2
Term Annotations click to browse term
  biological_process 18872
    cellular process 17581
      cellular component organization or biogenesis 6570
        cellular component organization 6338
          organelle organization 3922
            cytoskeleton organization 1503
              actin cytoskeleton organization 755
                actin filament organization 471
                  actin polymerization or depolymerization 210
                    regulation of actin polymerization or depolymerization 174
                      regulation of actin filament depolymerization 60
                        negative regulation of actin filament depolymerization 50
                          actin filament capping 44
                            barbed-end actin filament capping + 28
                            pointed-end actin filament capping 7
paths to the root