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ONTOLOGY REPORT - ANNOTATIONS


Term:norepinephrine uptake
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Accession:GO:0051620 term browser browse the term
Definition:The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
Synonyms:exact_synonym: levarterenol reuptake;   levarterenol uptake;   noradrenaline reuptake;   noradrenaline uptake;   norepinephrine import;   norepinephrine reuptake


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norepinephrine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a1 solute carrier family 22 member 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:9687576)
Ensembl
RGD
PMID:9687576 GO_REF:0000107 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a3 solute carrier family 22 member 3 involved_in ISO (PMID:20858707) RGD PMID:20858707 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc29a4 solute carrier family 29 member 4 involved_in ISO (PMID:20858707)
(MGI:6436398|PMID:20858707)
RGD PMID:20858707 MGI:6436398 NCBI chr12:13,914,114...13,924,511
Ensembl chr12:13,914,114...13,924,531
JBrowse link
G Slc6a2 solute carrier family 6 member 2 involved_in ISO (MGI:6436398|PMID:20858707) RGD PMID:20858707 MGI:6436398 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Slc6a3 solute carrier family 6 member 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
negative regulation of norepinephrine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha involved_in ISO (PMID:17156375) RGD PMID:17156375 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
regulation of norepinephrine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in IMP
IEA
IGI
ISO
PMID:18331289
GO_REF:0000107
UniProtKB:P37840 (PMID:18331289)
Ensembl
RGD
PMID:18331289, PMID:18331289, PMID:18331289 GO_REF:0000107, RGD:13601986, RGD:13601986 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Snca synuclein alpha involved_in ISO UniProtKB:P60709 (PMID:18331289) RGD PMID:18331289 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    localization 6449
      establishment of localization 4865
        transport 4700
          import into cell 232
            catecholamine uptake 17
              norepinephrine uptake 8
                negative regulation of norepinephrine uptake + 1
                positive regulation of norepinephrine uptake 0
                regulation of norepinephrine uptake + 2
Path 2
Term Annotations click to browse term
  biological_process 19599
    localization 6449
      establishment of localization 4865
        transport 4700
          organic substance transport 2465
            monoamine transport 107
              catecholamine transport 91
                norepinephrine transport 30
                  norepinephrine uptake 8
                    negative regulation of norepinephrine uptake + 1
                    positive regulation of norepinephrine uptake 0
                    regulation of norepinephrine uptake + 2
paths to the root