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ONTOLOGY REPORT - ANNOTATIONS

Term:norepinephrine uptake
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Accession:GO:0051620 term browser browse the term
Definition:The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
Synonyms:exact_synonym: levarterenol reuptake;   levarterenol uptake;   noradrenaline reuptake;   noradrenaline uptake;   norepinephrine import;   norepinephrine reuptake


show annotations for term's descendants           Sort by:
norepinephrine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC18A1 solute carrier family 18 member A1 involved_in ISO (PMID:23337945) UniProt PMID:23337945 NCBI chr 8:19,369,843...19,408,412
Ensembl chr 8:16,318,744...16,353,708 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,058,226...158,150,917
Ensembl chr 6:163,065,317...163,158,931 		JBrowse link
G SLC22A3 solute carrier family 22 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,240,390...158,344,338
Ensembl chr 6:163,247,643...163,349,735 		JBrowse link
G SLC29A4 solute carrier family 29 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,538,436...5,559,506
Ensembl chr 7:5,560,565...5,575,637 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr16:35,885,756...35,935,638
Ensembl chr16:54,990,773...55,040,504 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 involved_in IEA GOC GO_REF:0000108 Ensembl chr 5:1,437,567...1,488,829 JBrowse link
negative regulation of norepinephrine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha involved_in ISO (PMID:17156375) UniProt PMID:17156375 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
regulation of norepinephrine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA1 actin alpha 1, skeletal muscle involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:204,975,646...204,978,523
Ensembl chr 1:210,007,622...210,010,469 		JBrowse link
G ACTB actin beta involved_in IEA Ensembl GO_REF:0000107
G ACTG1 actin gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:75,965,911...75,968,822
Ensembl chr17:81,668,221...81,671,087 		JBrowse link
G ACTG2 actin gamma 2, smooth muscle involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:73,966,939...73,993,862
Ensembl chr2A:75,476,877...75,503,658 		JBrowse link
G LOC100987752 actin alpha cardiac muscle 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:13,707,475...13,712,905
Ensembl chr15:31,966,278...31,971,782 		JBrowse link
G LOC100990579 actin, cytoplasmic 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:162,333,291...162,335,130 JBrowse link
G SNCA synuclein alpha involved_in ISO (PMID:18331289) ARUK-UCL PMID:18331289 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    localization 5279
      establishment of localization 4578
        transport 4266
          organic substance transport 2250
            organic cation transport 139
              norepinephrine transport 38
                norepinephrine uptake 13
                  negative regulation of norepinephrine uptake + 1
                  positive regulation of norepinephrine uptake 0
                  regulation of norepinephrine uptake + 7
Path 2
Term Annotations click to browse term
  biological_process 16440
    localization 5279
      establishment of localization 4578
        transport 4266
          organic substance transport 2250
            organic hydroxy compound transport 312
              catecholamine transport 101
                norepinephrine transport 38
                  norepinephrine uptake 13
                    negative regulation of norepinephrine uptake + 1
                    positive regulation of norepinephrine uptake 0
                    regulation of norepinephrine uptake + 7
paths to the root