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ONTOLOGY REPORT - ANNOTATIONS

Term:serotonin uptake
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Accession:GO:0051610 term browser browse the term
Definition:The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
Synonyms:exact_synonym: 5-HT uptake;   5-hydroxytryptamine uptake;   5HT uptake;   serotonin import


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serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC18A1 solute carrier family 18 member A1 involved_in ISO
IEA		 RGD
GOC
Ensembl		 PMID:19008227 GO_REF:0000107 GO_REF:0000108 RGD:5131091 NCBI chr14:4,243,553...4,279,341
Ensembl chr14:4,243,557...4,275,243 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 involved_in ISO
IEA		 RGD
GOC
Ensembl		 PMID:20007701 GO_REF:0000107 GO_REF:0000108 RGD:5130957 NCBI chr14:127,357,605...127,394,242
Ensembl chr14:127,357,555...127,396,533 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:90,113,534...90,115,813
Ensembl chr14:90,113,844...90,115,430 		JBrowse link
G SLC18B1 solute carrier family 18 member B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,923,716...30,956,898
Ensembl chr 1:30,923,765...30,954,260 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,340,442...7,365,543
Ensembl chr 1:7,340,126...7,365,520 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,289,278...7,323,418
Ensembl chr 1:7,289,831...7,323,146 		JBrowse link
G SLC22A3 solute carrier family 22 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,105,486...7,207,395
Ensembl chr 1:7,110,074...7,207,401 		JBrowse link
G SLC29A4 solute carrier family 29 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:3,854,466...3,879,117
Ensembl chr 3:3,853,307...3,878,236 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
Ensembl
GOC		 PMID:12944413 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 GO_REF:0000118 RGD:1580638 NCBI chr12:46,285,995...46,328,377
Ensembl chr12:46,285,997...46,314,378 		JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPM6B glycoprotein M6B involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:10,429,496...10,582,768
Ensembl chr  X:10,430,301...10,582,354 		JBrowse link
G LOC110257945 neuronal membrane glycoprotein M6-b-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  Y:10,460,600...10,471,454 JBrowse link
G NOS1 nitric oxide synthase 1 involved_in ISO (MGI:3710710|PMID:17452640) UniProt PMID:17452640 MGI:3710710 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,944 		JBrowse link
G SLC18A1 solute carrier family 18 member A1 ISO G-protein mediated uptake inhibition RGD PMID:16926160 RGD:5130998 NCBI chr14:4,243,553...4,279,341
Ensembl chr14:4,243,557...4,275,243 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:129,247,724...129,388,307
Ensembl chr 8:129,248,819...129,271,128 		JBrowse link
regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB3 integrin subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,514...16,752,292 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    cellular process 16838
      cellular localization 3552
        establishment of localization in cell 2090
          neurotransmitter reuptake 31
            serotonin uptake 14
              negative regulation of serotonin uptake + 5
              positive regulation of serotonin uptake 0
              regulation of serotonin uptake + 6
Path 2
Term Annotations click to browse term
  biological_process 17799
    localization 5399
      establishment of localization 4701
        transport 4392
          organic substance transport 2351
            monoamine transport 113
              serotonin transport 30
                serotonin uptake 14
                  negative regulation of serotonin uptake + 5
                  positive regulation of serotonin uptake 0
                  regulation of serotonin uptake + 6
paths to the root