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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of neurotransmitter uptake
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Accession:GO:0051581 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
Synonyms:exact_synonym: down regulation of neurotransmitter uptake;   downregulation of neurotransmitter uptake;   negative regulation of neurotransmitter import


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negative regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha ISO (PMID:12958153) UniProtKB PMID:12958153 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpm6b glycoprotein M6B ISO (MGI:MGI:5426133|PMID:18581270) UniProtKB PMID:18581270 MGI:MGI:5426133 NCBI chrNW_004936470:3,332,856...3,496,178 JBrowse link
G Nos1 nitric oxide synthase 1 ISO (MGI:MGI:3710710|PMID:17452640) UniProtKB PMID:17452640 MGI:MGI:3710710 NCBI chrNW_004936558:5,162,471...5,302,488 JBrowse link
G Slc18a1 solute carrier family 18 member A1 ISO G-protein mediated uptake inhibition RGD PMID:16926160 RGD:5130998 NCBI chrNW_004936555:4,249,821...4,271,379 JBrowse link
G Snca synuclein alpha ISO (PMID:16882008) UniProtKB PMID:16882008 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11998
    negative regulation of biological process 4639
      negative regulation of transport 481
        negative regulation of neurotransmitter transport 17
          negative regulation of neurotransmitter uptake 4
            inhibition of neurotransmitter uptake + 0
            negative regulation of amino acid uptake involved in synaptic transmission + 0
            negative regulation of catecholamine uptake involved in synaptic transmission + 1
            negative regulation of histamine uptake + 0
            negative regulation of serotonin uptake + 4
Path 2
Term Annotations click to browse term
  biological_process 11998
    localization 4765
      establishment of localization 3410
        transport 3258
          regulation of transport 1670
            regulation of neurotransmitter transport 134
              regulation of neurotransmitter uptake 17
                negative regulation of neurotransmitter uptake 4
                  inhibition of neurotransmitter uptake + 0
                  negative regulation of amino acid uptake involved in synaptic transmission + 0
                  negative regulation of catecholamine uptake involved in synaptic transmission + 1
                  negative regulation of histamine uptake + 0
                  negative regulation of serotonin uptake + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.