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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of neurotransmitter uptake
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Accession:GO:0051580 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
Synonyms:exact_synonym: regulation of neurotransmitter import;   regulation of neurotransmitter reuptake


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regulation of neurotransmitter uptake term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092
JBrowse link
G DRD2 dopamine receptor D2 ISO (MGI:MGI:2387277|PMID:12223553) SynGO PMID:12223553 MGI:MGI:2387277 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 ISO (MGI:MGI:6189384|PMID:27393374) SynGO PMID:27393374 MGI:MGI:6189384 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G FLOT1 flotillin 1 IDA
IMP
(PMID:21399631) SynGO PMID:21399631 NCBI chr 6:30,727,709...30,742,847
Ensembl chr 6:30,727,709...30,742,732
JBrowse link
G GFAP glial fibrillary acidic protein IEA Ensembl GO_REF:0000107 NCBI chr17:44,903,159...44,915,552
Ensembl chr17:44,903,159...44,916,937
JBrowse link
negative regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha IDA (PMID:12958153) UniProtKB PMID:12958153 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPM6B glycoprotein M6B ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr  X:13,770,922...13,938,713
Ensembl chr  X:13,770,939...13,938,638
JBrowse link
G NOS1 nitric oxide synthase 1 ISS BHF-UCL GO_REF:0000024 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G SLC18A1 solute carrier family 18 member A1 ISO G-protein mediated uptake inhibition RGD PMID:16926160 RGD:5130998 NCBI chr 8:20,144,855...20,183,139
Ensembl chr 8:20,144,855...20,183,206
JBrowse link
G SNCA synuclein alpha IDA (PMID:16882008) UniProtKB PMID:16882008 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
positive regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISS BHF-UCL GO_REF:0000024 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD4 dopamine receptor D4 IC (PMID:1840645) BHF-UCL PMID:1840645 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G NAT8L N-acetyltransferase 8 like ISO (MGI:MGI:4943664|PMID:19014384) UniProtKB PMID:19014384 MGI:MGI:4943664 NCBI chr 4:2,059,327...2,069,089
Ensembl chr 4:2,059,327...2,069,089
Ensembl chr 4:2,059,327...2,069,089
JBrowse link
G RAB3B RAB3B, member RAS oncogene family IDA (PMID:20007772) UniProtKB PMID:20007772 NCBI chr 1:51,907,956...51,990,700
Ensembl chr 1:51,907,956...51,990,700
JBrowse link
positive regulation of glutamate uptake involved in transmission of nerve impulse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB1 integrin subunit beta 1 ISS ARUK-UCL GO_REF:0000024 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,900,318...33,005,792
JBrowse link
positive regulation of neurotransmitter uptake term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKN parkin RBR E3 ubiquitin protein ligase IMP (PMID:22314364) ParkinsonsUK-UCL PMID:22314364 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD1 dopamine receptor D1 IC (PMID:8301582) BHF-UCL PMID:8301582 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 IC (PMID:8301582) BHF-UCL PMID:8301582 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 IC (PMID:8301582) BHF-UCL PMID:8301582 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G GDNF glial cell derived neurotrophic factor IDA (PMID:8493557) UniProtKB PMID:8493557 NCBI chr 5:37,812,677...37,840,044
Ensembl chr 5:37,812,677...37,840,041
JBrowse link
G TOR1A torsin family 1 member A IDA (PMID:15505207) UniProtKB PMID:15505207 NCBI chr 9:129,812,942...129,824,136
Ensembl chr 9:129,812,942...129,824,244
JBrowse link
regulation of glutamate uptake involved in transmission of nerve impulse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 NAS (PMID:23954377) BHF-UCL PMID:23954377 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G PER2 period circadian regulator 2 ISS UniProtKB GO_REF:0000024 NCBI chr 2:238,244,038...238,290,102
Ensembl chr 2:238,244,044...238,290,102
JBrowse link
regulation of serotonin uptake term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB3 integrin subunit beta 3 ISS UniProt GO_REF:0000024 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    biological regulation 13309
      regulation of biological quality 4612
        regulation of neurotransmitter levels 285
          regulation of neurotransmitter uptake 20
            negative regulation of neurotransmitter uptake + 4
            positive regulation of neurotransmitter uptake + 6
            regulation of amino acid uptake involved in synaptic transmission + 3
            regulation of catecholamine uptake involved in synaptic transmission + 9
            regulation of histamine uptake + 0
            regulation of serotonin uptake + 5
Path 2
Term Annotations click to browse term
  biological_process 18670
    localization 7208
      establishment of localization 5657
        transport 5515
          neurotransmitter transport 275
            regulation of neurotransmitter transport 154
              regulation of neurotransmitter uptake 20
                negative regulation of neurotransmitter uptake + 4
                positive regulation of neurotransmitter uptake + 6
                regulation of amino acid uptake involved in synaptic transmission + 3
                regulation of catecholamine uptake involved in synaptic transmission + 9
                regulation of histamine uptake + 0
                regulation of serotonin uptake + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.