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ONTOLOGY REPORT - ANNOTATIONS


Term:elastin metabolic process
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Accession:GO:0051541 term browser browse the term
Definition:The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
Synonyms:exact_synonym: elastin metabolism



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elastin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
JBrowse link
G LEP leptin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5616293|PMID:23413430) MGI
Ensembl
PMID:23413430 GO_REF:0000107 MGI:5616293 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323
JBrowse link
elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (MGI:83737|PMID:8096378) MGI PMID:8096378 MGI:83737 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048
JBrowse link
elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CELA1 chymotrypsin like elastase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5641427|PMID:24793170) MGI
Ensembl
PMID:24793170 GO_REF:0000107 MGI:5641427
G CTSL cathepsin L involved_in ISO (MGI:6259330|PMID:12417635) UniProt PMID:12417635 MGI:6259330 NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618
JBrowse link
G CTSV cathepsin V involved_in ISS UniProt GO_REF:0000024 NCBI chr10:25,202,360...25,208,058
Ensembl chr10:25,202,389...25,209,210
JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:33,473,625...33,483,630
Ensembl chr 9:33,473,093...33,483,679
JBrowse link
negative regulation of elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HBEGF heparin binding EGF like growth factor involved_in ISO PMID:12882762 UniProt PMID:12882762 RGD:8554842 NCBI chr 2:142,102,455...142,115,192
Ensembl chr 2:142,102,458...142,115,174
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CST3 cystatin C involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,471,056...30,474,486
Ensembl chr17:30,470,855...30,474,590
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17778
    metabolic process 10327
      primary metabolic process 8980
        protein metabolic process 4030
          glycoprotein metabolic process 373
            elastin metabolic process 9
              elastin biosynthetic process + 2
              elastin catabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 17778
    metabolic process 10327
      organic substance metabolic process 9887
        macromolecule metabolic process 8335
          protein metabolic process 4030
            glycoprotein metabolic process 373
              elastin metabolic process 9
                elastin biosynthetic process + 2
                elastin catabolic process + 5
paths to the root