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ONTOLOGY REPORT - ANNOTATIONS


Term:elastin metabolic process
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Accession:GO:0051541 term browser browse the term
Definition:The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
Synonyms:exact_synonym: elastin metabolism



show annotations for term's descendants           Sort by:
elastin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G LEP leptin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5616293|PMID:23413430) MGI
Ensembl
PMID:23413430 GO_REF:0000107 MGI:5616293 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395
JBrowse link
elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (MGI:83737|PMID:8096378) MGI PMID:8096378 MGI:83737 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CELA1 chymotrypsin like elastase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5641427|PMID:24793170) MGI
Ensembl
PMID:24793170 GO_REF:0000107 MGI:5641427 NCBI chr27:3,542,327...3,560,777
Ensembl chr27:3,542,309...3,560,777
JBrowse link
G CTSL3 cathepsin L family member 3 involved_in ISO (MGI:6259330|PMID:12417635) UniProt PMID:12417635 MGI:6259330 NCBI chr 1:72,215,774...72,219,093 JBrowse link
G CTSV cathepsin V involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:69,937,550...69,943,316 JBrowse link
G LOC119866362 chymotrypsin-like elastase family member 1 involved_in IEA Ensembl GO_REF:0000107
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,918,626...28,933,404
Ensembl chr 5:28,918,594...28,933,309
JBrowse link
negative regulation of elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HBEGF heparin binding EGF like growth factor involved_in ISO PMID:12882762 UniProt PMID:12882762 RGD:8554842 NCBI chr 2:35,551,248...35,563,310
Ensembl chr 2:35,551,250...35,563,043
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC607874 cystatin-C-like involved_in ISO (PMID:10545518) BHF-UCL PMID:10545518 NCBI chr23:49,562...53,618 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17874
    metabolic process 10929
      primary metabolic process 9495
        protein metabolic process 4323
          glycoprotein metabolic process 386
            elastin metabolic process 10
              elastin biosynthetic process + 2
              elastin catabolic process + 6
Path 2
Term Annotations click to browse term
  biological_process 17874
    metabolic process 10929
      organic substance metabolic process 10474
        macromolecule metabolic process 8840
          protein metabolic process 4323
            glycoprotein metabolic process 386
              elastin metabolic process 10
                elastin biosynthetic process + 2
                elastin catabolic process + 6
paths to the root