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ONTOLOGY REPORT - ANNOTATIONS


Term:elastin metabolic process
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Accession:GO:0051541 term browser browse the term
Definition:The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
Synonyms:exact_synonym: elastin metabolism



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elastin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA
ISO
GO_REF:0000107
(MGI:3772289|PMID:18037992)
Ensembl
RGD
PMID:18037992 GO_REF:0000107 MGI:3772289 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:1856424 (MGI:5616293|PMID:23413430) RGD PMID:23413430 MGI:5616293 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856101 (MGI:83737|PMID:8096378) RGD PMID:8096378 MGI:83737 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin like elastase 1 acts_upstream_of_or_within ISO (MGI:5641427|PMID:24793170) RGD PMID:24793170 MGI:5641427 NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285
JBrowse link
G Ctsl cathepsin L involved_in ISS
ISO
GO_REF:0000024
(MGI:6259330|PMID:12417635)
UniProt
RGD
PMID:12417635 GO_REF:0000024 MGI:6259330 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO
IEA
(PMID:29101312)
GO_REF:0000107
RGD
Ensembl
PMID:29101312 GO_REF:0000107 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
negative regulation of elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hbegf heparin-binding EGF-like growth factor involved_in IDA PMID:12882762 UniProt PMID:12882762 RGD:8554842 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    cellular process 18691
      cellular metabolic process 10465
        cellular macromolecule metabolic process 3732
          glycoprotein metabolic process 395
            elastin metabolic process 8
              elastin biosynthetic process + 2
              elastin catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 20094
    metabolic process 12347
      organic substance metabolic process 11867
        macromolecule metabolic process 10212
          protein metabolic process 6227
            glycoprotein metabolic process 395
              elastin metabolic process 8
                elastin biosynthetic process + 2
                elastin catabolic process + 4
paths to the root