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ONTOLOGY REPORT - ANNOTATIONS


Term:elastin metabolic process
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Accession:GO:0051541 term browser browse the term
Definition:The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
Synonyms:exact_synonym: elastin metabolism


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elastin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA
ISO
GO_REF:0000107
(MGI:3772289|PMID:18037992)
Ensembl
RGD
PMID:18037992 GO_REF:0000107 MGI:3772289 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:1856424 (MGI:5616293|PMID:23413430) RGD PMID:23413430 MGI:5616293 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856101 (MGI:83737|PMID:8096378) RGD PMID:8096378 MGI:83737 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin like elastase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5641427|PMID:24793170)
Ensembl
RGD
PMID:24793170 GO_REF:0000107 MGI:5641427 NCBI chr 7:142,305,337...142,318,621
Ensembl chr 7:142,305,338...142,318,620
JBrowse link
G Ctsl cathepsin L involved_in ISS
ISO
GO_REF:0000024
(MGI:6259330|PMID:12417635)
UniProt
RGD
PMID:12417635 GO_REF:0000024 MGI:6259330 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO
IEA
(PMID:29101312)
GO_REF:0000107
RGD
Ensembl
PMID:29101312 GO_REF:0000107 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
negative regulation of elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hbegf heparin-binding EGF-like growth factor involved_in IDA PMID:12882762 UniProt PMID:12882762 RGD:8554842 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      cellular metabolic process 10755
        cellular macromolecule metabolic process 8243
          glycoprotein metabolic process 358
            elastin metabolic process 8
              elastin biosynthetic process + 2
              elastin catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      organic substance metabolic process 11337
        macromolecule metabolic process 9793
          protein metabolic process 5893
            glycoprotein metabolic process 358
              elastin metabolic process 8
                elastin biosynthetic process + 2
                elastin catabolic process + 4
paths to the root