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ONTOLOGY REPORT - ANNOTATIONS

Term:2 iron, 2 sulfur cluster binding
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Accession:GO:0051537 term browser browse the term
Definition:Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
Synonyms:exact_synonym: 2 Fe 2 S cluster binding;   2 iron, 2 sulphur cluster binding;   2Fe-2S cluster binding;   diiron disulfide cluster binding;   diiron disulphide cluster binding;   iron-sulfur cluster 2Fe-2S binding;   iron-sulphur cluster 2Fe-2S binding


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2 iron, 2 sulfur cluster binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034928.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr12:439,533...439,826 JBrowse link
G Aifm3 apoptosis inducing factor, mitochondria associated 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248 		JBrowse link
G Aox1 aldehyde oxidase 1 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26322824), (PMID:26842593)
GO_REF:0000043		 UniProt
Ensembl
RGD		 PMID:26322824 PMID:26842593 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Aox2 aldehyde oxidase 2 enables ISS
IEA		 GO_REF:0000024
GO_REF:0000043		 UniProt GO_REF:0000024 GO_REF:0000043 NCBI chr 9:59,828,403...59,916,175
Ensembl chr 9:59,828,084...59,916,146 		JBrowse link
G Aox3 aldehyde oxidase 3 enables ISS
IEA		 GO_REF:0000024
GO_REF:0000043		 UniProt GO_REF:0000024 GO_REF:0000043 NCBI chr 9:59,664,784...59,749,701
Ensembl chr 9:59,664,809...59,818,169 		JBrowse link
G Aox4 aldehyde oxidase 4 enables IEA
ISS		 GO_REF:0000043
GO_REF:0000024		 UniProt GO_REF:0000024 GO_REF:0000043 NCBI chr 9:59,761,238...59,818,169
Ensembl chr 9:59,664,809...59,818,169 		JBrowse link
G Bola2 bolA family member 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:181,291,967...181,292,833
Ensembl chr 1:181,291,398...181,292,676 		JBrowse link
G Bola2-ps1 bolA family member 2, pseudogene 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:55,904,340...55,904,691
Ensembl chr 8:55,904,379...55,904,639 		JBrowse link
G Bola2-ps1 bolA family member 2, pseudogene 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 8:55,904,379...55,904,639 JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:27519415)
GO_REF:0000104		 UniProt
RGD		 PMID:27519415 GO_REF:0000024 GO_REF:0000104 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 enables ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:17766439), (PMID:17766440), (PMID:17905743), (PMID:21788481), (PMID:23758282)
GO_REF:0000104
GO_REF:0000043
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:17766439 PMID:17766440 PMID:17905743 PMID:21788481 PMID:23758282 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000104 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924 		JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 enables ISO
IBA		 (PMID:19580816)
GO_REF:0000033		 RGD
GO_Central		 PMID:19580816 GO_REF:0000033 NCBI chr 2:223,828,937...223,853,768
Ensembl chr 2:223,828,937...223,868,946 		JBrowse link
G Cisd3 CDGSH iron sulfur domain 3 enables ISO
IBA		 (PMID:29259115)
GO_REF:0000033		 RGD
GO_Central		 PMID:29259115 GO_REF:0000033 NCBI chr10:82,679,345...82,682,376
Ensembl chr10:82,679,196...82,682,550 		JBrowse link
G Cmahp cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275 		JBrowse link
G ENSRNOG00000062366 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 3:153,272,475...153,273,513 JBrowse link
G Fdx1 ferredoxin 1 enables ISO
IEA
ISS		 (PMID:21636783)
GO_REF:0000107
GO_REF:0000024
GO_REF:0000002		 RGD
Ensembl
UniProt
InterPro		 PMID:21636783 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fdx2 ferredoxin 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849 		JBrowse link
G Fxn frataxin enables ISO
IEA
IBA		 (PMID:12785837)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:12785837 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Glrx2 glutaredoxin 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831 		JBrowse link
G Glrx3 glutaredoxin 3 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955 		JBrowse link
G Isca2 iron-sulfur cluster assembly 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:104,418,509...104,420,019
Ensembl chr 6:104,418,454...104,420,045 		JBrowse link
G Iscu iron-sulfur cluster assembly enzyme enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Rfesd Rieske (Fe-S) domain containing enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:5,495,067...5,521,095
Ensembl chr 2:5,505,756...5,522,449 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:15989954)
GO_REF:0000043		 UniProt
RGD		 PMID:15989954 GO_REF:0000024 GO_REF:0000043 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Slc25a39 solute carrier family 25, member 39 enables ISO
ISS		 (PMID:37917749), (PMID:38157846)
GO_REF:0000024		 RGD
UniProt		 PMID:37917749 PMID:38157846 GO_REF:0000024 NCBI chr10:87,362,494...87,367,358
Ensembl chr10:87,362,490...87,367,260 		JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479 		JBrowse link
G Xdh xanthine dehydrogenase enables IDA
IEA
ISO
ISS		 GO_REF:0000107
PMID:15878860
(PMID:17301077)
GO_REF:0000024
GO_REF:0000043		 Ensembl
RGD
UniProt		 PMID:17301077 PMID:2549869 PMID:15878860 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107, RGD:13209004, RGD:8553512 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 21010
    binding 18037
      small molecule binding 6207
        metal cluster binding 76
          iron-sulfur cluster binding 73
            2 iron, 2 sulfur cluster binding 30
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