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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of stress fiber assembly
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Accession:GO:0051497 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
Synonyms:narrow_synonym: inhibition of stress fiber formation
 related_synonym: down regulation of stress fiber formation;   downregulation of stress fiber formation;   negative regulation of stress fibre biosynthesis;   negative regulation of stress fibre formation


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negative regulation of stress fiber assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 involved_in ISO (PMID:11804590) RGD PMID:11804590 NCBI chr 1:155,748,622...155,814,186
Ensembl chr 1:155,748,652...155,814,184 		JBrowse link
G Arhgap28 Rho GTPase activating protein 28 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:25211221)		 GO_Central
RGD		 PMID:25211221 GO_REF:0000033 NCBI chr 9:107,832,584...107,998,030
Ensembl chr 9:107,833,330...107,998,000 		JBrowse link
G Arhgap6 Rho GTPase activating protein 6 involved_in ISO (PMID:10699171) RGD PMID:10699171 NCBI chr  X:24,953,464...25,490,003
Ensembl chr  X:24,953,464...25,488,663 		JBrowse link
G Arhgef18 Rho/Rac guanine nucleotide exchange factor 18 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr12:1,395,035...1,503,082
Ensembl chr12:1,395,088...1,503,081 		JBrowse link
G Cgnl1 cingulin-like 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917 		JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Coro2b coronin 2B acts_upstream_of_or_within ISO MGI:4419137 (PMID:29162887) RGD PMID:29162887 NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein involved_in ISO
IEA		 (PMID:17932950)
GO_REF:0000107		 RGD
Ensembl		 PMID:17932950 GO_REF:0000107 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G F11r F11 receptor involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Frmd7 FERM domain containing 7 acts_upstream_of_or_within ISO (PMID:23967341) RGD PMID:23967341 NCBI chr  X:130,375,925...130,423,836
Ensembl chr  X:130,377,227...130,423,771 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) RGD PMID:12556481 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA		 (PMID:25198505)
GO_REF:0000107		 RGD
Ensembl		 PMID:25198505 GO_REF:0000107 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mir138-1 microRNA 138-1 involved_in ISO (PMID:20232393) RGD PMID:20232393 NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064 		JBrowse link
G Mir138-2 microRNA 138-2 involved_in ISO (PMID:20232393) RGD PMID:20232393 NCBI chr19:10,674,193...10,674,274
Ensembl chr19:10,674,193...10,674,274 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:22696064) RGD PMID:22696064 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:21347332) RGD PMID:21347332 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Myoc myocilin involved_in ISO
IEA
ISS		 (PMID:17984096)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17984096 GO_REF:0000024 GO_REF:0000107 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Pfn1 profilin 1 involved_in ISO
IEA		 (PMID:23153535)
GO_REF:0000107		 RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6450670|PMID:11038173)		 Ensembl
RGD		 PMID:11038173 GO_REF:0000107 MGI:6450670 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 acts_upstream_of_or_within ISO (PMID:22266902) RGD PMID:22266902 NCBI chr 1:199,641,277...199,718,371
Ensembl chr 1:199,641,277...199,717,277 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:12052877 RGD:1299363 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Rhpn1 rhophilin, Rho GTPase binding protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:25071083)		 GO_Central
RGD		 PMID:25071083 GO_REF:0000033 NCBI chr 7:107,391,948...107,402,713
Ensembl chr 7:107,391,984...107,402,713 		JBrowse link
G Rhpn2 rhophilin, Rho GTPase binding protein 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:25071083)
GO_REF:0000033		 RGD
GO_Central		 PMID:25071083 GO_REF:0000033 NCBI chr 1:87,991,143...88,051,895
Ensembl chr 1:87,991,144...88,051,902 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:11094076 RGD:1581790 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5315060|PMID:22194864)		 Ensembl
UniProt
RGD		 PMID:22194864 GO_REF:0000024 GO_REF:0000107 MGI:5315060 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (MGI:6206452|PMID:25753039) RGD PMID:25753039 MGI:6206452 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 acts_upstream_of_or_within ISO (PMID:24632071) RGD PMID:24632071 NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475 		JBrowse link
G Tmsb15b2 thymosin beta 15B2 acts_upstream_of_or_within ISO (PMID:19233202) RGD PMID:19233202 NCBI chr  X:100,298,705...100,300,820
Ensembl chr  X:100,298,514...100,300,886 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO (PMID:8625410) RGD PMID:8625410 NCBI chr  X:14,405,105...14,413,850
Ensembl chr  X:14,405,124...14,413,849 		JBrowse link
G Wasf2 WASP family member 2 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 5:145,336,817...145,402,041
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      regulation of cellular process 12748
        regulation of cellular component biogenesis 1176
          regulation of actin filament bundle assembly 120
            regulation of stress fiber assembly 100
              negative regulation of stress fiber assembly 34
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular component organization or biogenesis 7290
        cellular component organization 6980
          organelle organization 3887
            cytoskeleton organization 1643
              actin cytoskeleton organization 786
                actin filament organization 517
                  actin filament bundle organization 195
                    actin filament bundle assembly 192
                      contractile actin filament bundle assembly 121
                        stress fiber assembly 121
                          regulation of stress fiber assembly 100
                            negative regulation of stress fiber assembly 34
paths to the root