regulation of cytoskeleton organization - Ontology Report

GO_REF:0000002

NCBI chr 8:3,070,031...3,198,319
Ensembl chr 8:3,069,954...3,202,536

ARHGEF5

Rho guanine nucleotide exchange factor 5

involved_in

GO_REF:0000107

NCBI chr 9:113,364,849...113,394,446
Ensembl chr 9:113,364,879...113,394,389

CAPN2

calpain 2

involved_in

GO_REF:0000002

NCBI chr10:19,758,824...19,820,241
Ensembl chr10:19,758,762...19,851,989

CAPN6

calpain 6

involved_in

GO_REF:0000107

NCBI chr X:91,258,696...91,288,128
Ensembl chr X:91,258,712...91,288,020

CLN3

CLN3 lysosomal/endosomal transmembrane protein, battenin

involved_in

GO_REF:0000107

NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,559...18,450,293

CNTRL

centriolin

involved_in

GO_REF:0000002

NCBI chr 1:261,133,576...261,227,110

DIAPH1

diaphanous related formin 1

involved_in

GO_REF:0000107

NCBI chr 2:143,158,691...143,271,110
Ensembl chr 2:143,158,584...143,271,147

DYNLT1

dynein light chain Tctex-type 1

involved_in

PMID:15992542

NCBI chr 1:8,556,083...8,562,865
Ensembl chr 1:8,556,059...8,563,679

F11 receptor

involved_in

GO_REF:0000107

NCBI chr 4:89,425,101...89,447,889
Ensembl chr 4:89,425,039...89,449,932

LOC102166678

centriolin-like

involved_in

GO_REF:0000002

MAPK1

mitogen-activated protein kinase 1

involved_in

GO_REF:0000117

NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523

MAPK3

mitogen-activated protein kinase 3

involved_in

GO_REF:0000117

NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567

MARK2

microtubule affinity regulating kinase 2

involved_in

PMID:14517247

NCBI chr 2:8,153,870...8,216,141
Ensembl chr 2:8,155,321...8,215,706

MYCBP2

MYC binding protein 2

involved_in
acts_upstream_of_or_within

(MGI:3776727|PMID:18031680)

PMID:18031680

GO_REF:0000107 MGI:3776727

NCBI chr11:49,163,969...49,432,865
Ensembl chr11:49,164,141...49,432,858

NEXN

nexilin F-actin binding protein

involved_in

GO_REF:0000107

NCBI chr 6:135,315,000...135,382,911
Ensembl chr 6:135,318,754...135,382,699

PAK2

p21 (RAC1) activated kinase 2

involved_in

GO_REF:0000107

NCBI chr13:133,276,122...133,383,506
Ensembl chr13:133,283,300...133,496,071

PLXNB1

plexin B1

involved_in

GO_REF:0000107

NCBI chr13:31,113,910...31,140,133
Ensembl chr13:31,113,914...31,140,218

SPATA4

spermatogenesis associated 4

involved_in

(PMID:21873635)

NCBI chr15:38,698,822...38,705,784
Ensembl chr15:38,698,125...38,706,146

SPEF1

sperm flagellar 1

involved_in

(PMID:21873635)

NCBI chr17:31,934,856...31,938,463
Ensembl chr17:31,934,832...31,941,621

STMN3

stathmin 3

involved_in

(MGI:3706230|PMID:17135267)

HGNC-UCL

PMID:17135267

MGI:3706230

NCBI chr17:62,600,450...62,609,851
Ensembl chr17:62,551,171...62,608,843

SYDE1

synapse defective Rho GTPase homolog 1

involved_in

GO_REF:0000107

NCBI chr 2:62,447,030...62,453,944
Ensembl chr 2:62,447,036...62,453,949

TAOK1

TAO kinase 1

involved_in

PMID:14517247

NCBI chr12:45,597,067...45,750,117
Ensembl chr12:45,597,057...45,744,356

TJP1

tight junction protein 1

involved_in

(PMID:25753039)

PMID:25753039

NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,368...145,195,836

actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AVIL

advillin

involved_in

GO_REF:0000043

NCBI chr 5:23,087,946...23,110,602
Ensembl chr 5:23,087,956...23,132,465

CAPG

capping actin protein, gelsolin like

involved_in

GO_REF:0000043

NCBI chr 3:59,335,483...59,366,855
Ensembl chr 3:59,335,465...59,366,846

CAPZA1

capping actin protein of muscle Z-line subunit alpha 1

involved_in

GO_REF:0000043

NCBI chr 4:107,769,570...107,821,806
Ensembl chr 4:107,768,080...107,821,819

CAPZA2

capping actin protein of muscle Z-line subunit alpha 2

involved_in

GO_REF:0000043

NCBI chr18:29,316,384...29,365,062
Ensembl chr18:29,310,756...29,365,144

CAPZA3

capping actin protein of muscle Z-line subunit alpha 3

involved_in

GO_REF:0000043

NCBI chr 5:54,406,245...54,408,330

CAPZB

capping actin protein of muscle Z-line subunit beta

involved_in

GO_REF:0000043

NCBI chr 6:77,780,682...77,912,653
Ensembl chr 6:77,780,681...77,912,617

gelsolin

involved_in

Ensembl
UniProt

GO_REF:0000043 GO_REF:0000107

NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287

gelsolin

involved_in

GO_REF:0000043

LOC100037956

F-actin capping protein subunit beta 2

involved_in

GO_REF:0000043

MYH9

myosin heavy chain 9

NOT|involved_in

(MGI:5619440|PMID:23325791)

PMID:23325791

MGI:5619440

NCBI chr 5:11,365,603...11,456,475

RDX

radixin

involved_in

GO_REF:0000043

NCBI chr 9:38,243,608...38,299,561
Ensembl chr 9:38,220,441...38,376,439

SCIN

scinderin

involved_in

Ensembl
Ensembl
UniProt

GO_REF:0000043 GO_REF:0000107

NCBI chr 9:82,103,271...82,185,254
Ensembl chr 9:82,103,087...82,363,745

SPTA1

spectrin alpha, erythrocytic 1

involved_in

GO_REF:0000043

NCBI chr 4:91,573,470...91,640,057
Ensembl chr 4:91,485,067...91,640,063

SPTAN1

spectrin alpha, non-erythrocytic 1

involved_in

GO_REF:0000043

NCBI chr 1:268,936,120...269,002,261
Ensembl chr 1:268,936,025...269,002,261

SPTB

spectrin beta, erythrocytic

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr 7:88,812,717...88,954,471
Ensembl chr 7:88,812,715...88,954,306

SPTBN1

spectrin beta, non-erythrocytic 1

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr 3:86,585,225...86,784,316
Ensembl chr 3:86,585,050...86,784,107

SPTBN2

spectrin beta, non-erythrocytic 2

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr 2:5,683,414...5,739,418
Ensembl chr 2:5,695,858...5,739,417

SPTBN4

spectrin beta, non-erythrocytic 4

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr 6:48,729,839...48,812,799
Ensembl chr 6:48,729,750...48,812,796

tropomyosin 1

NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,981...109,019,440

villin 1

involved_in

UniProt
UniProt
Ensembl
InterPro

GO_REF:0000002 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580

VILL

villin like

involved_in

GO_REF:0000043

NCBI chr13:22,831,867...22,851,282
Ensembl chr13:22,831,915...22,851,275

actin filament uncapping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTN2

actinin alpha 2

involved_in

GO_REF:0000107

NCBI chr14:54,670,727...54,742,717
Ensembl chr14:54,666,623...54,742,779

barbed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADD1

adducin 1

involved_in

(PMID:21873635)

NCBI chr 8:1,627,146...1,710,653
Ensembl chr 8:1,627,177...1,710,661

ADD2

adducin 2

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 3:71,729,882...71,845,761
Ensembl chr 3:71,730,002...71,840,862

ADD3

adducin 3

involved_in

(PMID:21873635)

NCBI chr14:120,451,421...120,583,725
Ensembl chr14:120,451,573...120,583,723

AVIL

advillin

involved_in

(PMID:21873635)

NCBI chr 5:23,087,946...23,110,602
Ensembl chr 5:23,087,956...23,132,465

CAPG

capping actin protein, gelsolin like

involved_in

UniProt
GO_Central
UniProt
InterPro
GO_Central

(PMID:21873635)

PMID:17656356 PMID:21873635

GO_REF:0000002 GO_REF:0000104

NCBI chr 3:59,335,483...59,366,855
Ensembl chr 3:59,335,465...59,366,846

CAPZA1

capping actin protein of muscle Z-line subunit alpha 1

involved_in
acts_upstream_of_or_within

IEA
IBA
ISO

(PMID:21873635)
(MGI:3758397|PMID:17656356)

UniProt
InterPro
GO_Central
UniProt
MGI

GO_REF:0000002 GO_REF:0000104 MGI:3758397

NCBI chr 4:107,769,570...107,821,806
Ensembl chr 4:107,768,080...107,821,819

CAPZA2

capping actin protein of muscle Z-line subunit alpha 2

involved_in

GO_Central
InterPro
GO_Central
UniProt
UniProt

(PMID:21873635)

GO_REF:0000002 GO_REF:0000104

NCBI chr18:29,316,384...29,365,062
Ensembl chr18:29,310,756...29,365,144

CAPZA3

capping actin protein of muscle Z-line subunit alpha 3

involved_in

InterPro
UniProt

GO_REF:0000002 GO_REF:0000104

NCBI chr 5:54,406,245...54,408,330

CAPZB

capping actin protein of muscle Z-line subunit beta

involved_in
acts_upstream_of_or_within

GO_Central
UniProt
InterPro
GO_Central
MGI
UniProt

(PMID:21873635)
(MGI:3758397|PMID:17656356)

PMID:17656356 PMID:21873635

GO_REF:0000002 GO_REF:0000104 MGI:3758397

NCBI chr 6:77,780,682...77,912,653
Ensembl chr 6:77,780,681...77,912,617

DBNL

drebrin like

NOT|acts_upstream_of_or_within

(MGI:1353214|PMID:10637315)

PMID:10637315

MGI:1353214

NCBI chr18:48,713,335...48,725,692
Ensembl chr18:48,713,340...48,725,697

EPS8

epidermal growth factor receptor pathway substrate 8

involved_in

InterPro
Ensembl
InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr 5:56,817,445...57,005,117
Ensembl chr 5:56,817,606...57,005,114

FLII

FLII actin remodeling protein

involved_in

(PMID:21873635)

NCBI chr12:60,475,722...60,487,376
Ensembl chr12:60,475,733...60,487,415

gelsolin

involved_in

InterPro
GO_Central
InterPro

(PMID:21873635)

GO_REF:0000002

NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287

gelsolin

involved_in

GO_Central
InterPro
GO_Central

(PMID:21873635)

GO_REF:0000002

LOC100037956

F-actin capping protein subunit beta 2

involved_in

InterPro
UniProt

GO_REF:0000002 GO_REF:0000104

radixin

NCBI chr 9:38,243,608...38,299,561
Ensembl chr 9:38,220,441...38,376,439

SCIN

scinderin

involved_in

(PMID:21873635)

NCBI chr 9:82,103,271...82,185,254
Ensembl chr 9:82,103,087...82,363,745

SVIL

supervillin

involved_in

(PMID:21873635)

NCBI chr10:41,176,358...41,462,750
Ensembl chr10:41,177,977...41,462,766

twinfilin actin binding protein 1

involved_in

Ensembl
GO_Central
Ensembl
GO_Central

(PMID:21873635)

GO_REF:0000107

NCBI chr 5:74,868,586...74,881,220
Ensembl chr 5:74,868,585...74,893,713

TWF2

twinfilin actin binding protein 2

involved_in

(PMID:21873635)

NCBI chr13:34,361,294...34,370,997
Ensembl chr13:34,361,292...34,371,842

villin 1

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580

VILL

villin like

involved_in

(PMID:21873635)

NCBI chr13:22,831,867...22,851,282
Ensembl chr13:22,831,915...22,851,275

barbed-end actin filament uncapping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

capping protein regulator and myosin 1 linker 1

involved_in

Ensembl
Ensembl
InterPro
InterPro

GO_REF:0000002 GO_REF:0000107

NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,739...20,353,431

negative regulation of actin cytoskeleton reorganization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TJP1

tight junction protein 1

involved_in

(PMID:25753039)

PMID:25753039

NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,368...145,195,836

negative regulation of actin filament bundle assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cofilin 1

NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035

drebrin 1

NCBI chr 2:80,480,603...80,495,797
Ensembl chr 2:80,479,460...80,496,873

MAP3K1

mitogen-activated protein kinase kinase kinase 1

prevents phenylephrine-induced actin organization

RGD

PMID:9155015

RGD:2293527

NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,871,799...35,946,987

profilin 1

involved_in

(PMID:23153535)

NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,696...51,973,660

PRKN

parkin RBR E3 ubiquitin protein ligase

involved_in

GO_REF:0000107

NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,511...6,730,881

SHANK1

SH3 and multiple ankyrin repeat domains 1

acts_upstream_of_or_within

(MGI:3846509|PMID:19208628)

PMID:19208628

MGI:3846509

NCBI chr 6:55,452,095...55,496,304

SHANK3

SH3 and multiple ankyrin repeat domains 3

involved_in
acts_upstream_of_or_within

(MGI:3846509|PMID:19208628)

PMID:19208628

GO_REF:0000107 MGI:3846509

NCBI chr 5:41,376...93,033
Ensembl chr 5:41,786...93,177

negative regulation of actin filament depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cofilin 1

NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035

LIMA1

LIM domain and actin binding 1

involved_in

InterPro
Ensembl
InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr 5:16,074,436...16,177,122
Ensembl chr 5:16,074,436...16,177,104

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,277,232

PLEKHH2

pleckstrin homology, MyTH4 and FERM domain containing H2

involved_in

Ensembl
GO_Central
Ensembl
GO_Central

(PMID:21873635)

GO_REF:0000107

NCBI chr 3:96,707,397...96,833,431
Ensembl chr 3:96,707,397...96,834,189

SHROOM2

shroom family member 2

acts_upstream_of_or_within

(MGI:3723326|PMID:17666436)

PMID:17666436

MGI:3723326

NCBI chr  X:6,296,212...6,450,401
NCBI chr  Y:4,753,733...4,785,766
Ensembl chr  X:6,296,133...6,448,126

SPECC1L

sperm antigen with calponin homology and coiled-coil domains 1 like

acts_upstream_of_or_within

(MGI:5433266|PMID:21703590)

PMID:21703590

MGI:5433266

NCBI chr14:49,332,937...49,463,965

SWAP70

switching B cell complex subunit SWAP70

involved_in

GO_REF:0000107

NCBI chr 2:49,721,120...49,805,262
Ensembl chr 2:49,719,669...49,804,883

negative regulation of actin filament polymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adducin 1

NCBI chr 8:1,627,146...1,710,653
Ensembl chr 8:1,627,177...1,710,661

ARFGEF1

ADP ribosylation factor guanine nucleotide exchange factor 1

involved_in

GO_REF:0000107

NCBI chr 4:67,465,517...67,613,611
Ensembl chr 4:67,466,014...67,639,442

BBS4

Bardet-Biedl syndrome 4

acts_upstream_of_or_within
involved_in

(MGI:5510934|PMID:23716571)

PMID:23716571

GO_REF:0000107 MGI:5510934

NCBI chr 7:60,631,913...60,693,359

calpain 1

NCBI chr 2:6,997,513...7,024,410
Ensembl chr 2:6,997,516...7,081,432

CYRIB

CYFIP related Rac1 interactor B

involved_in

(PMID:30250061)

PMID:30250061

NCBI chr 4:10,476,137...10,643,395

FHOD3

formin homology 2 domain containing 3

involved_in
acts_upstream_of_or_within

(MGI:4422153|PMID:19706596)

PMID:19706596

GO_REF:0000107 MGI:4422153

NCBI chr 6:120,036,824...120,585,987
Ensembl chr 6:120,036,838...120,586,849

HIP1R

huntingtin interacting protein 1 related

involved_in

GO_REF:0000107

NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216

KANK1

KN motif and ankyrin repeat domains 1

involved_in
acts_upstream_of_or_within

GO_Central
Ensembl
GO_Central
MGI
Ensembl

(PMID:21873635)
(PMID:17996375)

PMID:17996375 PMID:21873635

GO_REF:0000107

NCBI chr 1:221,015,042...221,218,875
Ensembl chr 1:221,015,046...221,218,575

KANK3

KN motif and ankyrin repeat domains 3

involved_in

(PMID:21873635)

NCBI chr 2:70,938,732...70,953,543
Ensembl chr 2:70,938,787...70,953,543

KANK4

KN motif and ankyrin repeat domains 4

involved_in

(PMID:21873635)

NCBI chr 6:150,106,628...150,185,667
Ensembl chr 6:150,106,876...150,185,660

MKKS

MKKS centrosomal shuttling protein

involved_in
acts_upstream_of_or_within

(MGI:5510934|PMID:23716571)

PMID:23716571

GO_REF:0000107 MGI:5510934

NCBI chr17:19,341,024...19,363,007
Ensembl chr17:19,340,977...19,362,871

MYADM

myeloid associated differentiation marker

involved_in

GO_REF:0000107

NCBI chr 6:56,236,306...56,278,577
Ensembl chr 6:56,236,306...56,278,582

PECAM1

platelet and endothelial cell adhesion molecule 1

NCBI chr12:14,667,643...14,723,296
Ensembl chr12:14,582,481...14,723,336

profilin 1

involved_in

(PMID:7758455)

PMID:7758455

NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,696...51,973,660

profilin 2

involved_in
acts_upstream_of_or_within

PMID:7758455 PMID:18001770

(PMID:7758455)
(MGI:4844066|PMID:18001770)

UniProt
MGI

MGI:4844066

NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742

PRKCD

protein kinase C delta

involved_in

GO_REF:0000107

NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,264...35,323,356

SLIT2

slit guidance ligand 2

involved_in

GO_REF:0000107

NCBI chr 8:14,758,426...15,149,515
Ensembl chr 8:14,756,619...15,149,510

SSH1

slingshot protein phosphatase 1

involved_in

GO_REF:0000002

NCBI chr14:41,963,946...42,030,842
Ensembl chr14:41,968,466...42,025,726

SSH2

slingshot protein phosphatase 2

involved_in

GO_Central
InterPro
GO_Central

(PMID:21873635)

GO_REF:0000002

NCBI chr12:45,818,103...46,085,720

SSH3

slingshot protein phosphatase 3

involved_in

GO_Central
GO_Central
InterPro
InterPro

(PMID:21873635)

GO_REF:0000002

NCBI chr 2:5,185,480...5,193,875
Ensembl chr 2:5,185,489...5,192,846

TLR2

toll like receptor 2

involved_in

(MGI:5307186|PMID:22198949)

PMID:22198949

MGI:5307186

NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850

twinfilin actin binding protein 1

involved_in

InterPro
InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr 5:74,868,586...74,881,220
Ensembl chr 5:74,868,585...74,893,713

TWF2

twinfilin actin binding protein 2

involved_in

InterPro
InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr13:34,361,294...34,370,997
Ensembl chr13:34,361,292...34,371,842

negative regulation of actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARPIN

actin related protein 2/3 complex inhibitor

involved_in

GO_Central
Ensembl
InterPro
GO_Central
InterPro

(PMID:21873635)

GO_REF:0000002 GO_REF:0000107

NCBI chr 7:55,469,015...55,483,632

coronin 1A

involved_in

GO_REF:0000107

NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,899...18,342,380

negative regulation of Arp2/3 complex-mediated actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CORO1B

coronin 1B

involved_in

GO_REF:0000107

NCBI chr 2:5,081,294...5,086,698
Ensembl chr 2:5,080,660...5,086,698

CTNNA2

catenin alpha 2

involved_in

GO_REF:0000107

NCBI chr 3:63,205,073...64,417,990

DNAI3

dynein axonemal intermediate chain 3

involved_in

GO_REF:0000107

NCBI chr 4:130,765,580...130,826,828
Ensembl chr 4:130,765,354...130,826,630

GMFB

glia maturation factor beta

involved_in

GO_Central
GO_Central
InterPro
InterPro

(PMID:21873635)

PMID:21873635 PMID:23727094

GO_REF:0000002

NCBI chr 1:183,846,672...183,863,396
Ensembl chr 1:183,846,672...183,863,392

GMFG

glia maturation factor gamma

involved_in
acts_upstream_of_or_within

IEA
IBA
ISO

(PMID:21873635)
(MGI:5505367|PMID:23727094)

InterPro
GO_Central
Ensembl
InterPro
MGI
GO_Central
Ensembl

GO_REF:0000002 GO_REF:0000107 MGI:5505367

NCBI chr 6:47,990,241...47,997,332
Ensembl chr 6:47,990,237...48,000,590

HIP1R

huntingtin interacting protein 1 related

involved_in

GO_REF:0000107

NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216

PICK1

protein interacting with PRKCA 1

involved_in

PMID:18297063

NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,450...9,889,930

negative regulation of barbed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

capping protein regulator and myosin 1 linker 1

involved_in

InterPro
Ensembl
InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,739...20,353,431

CARMIL2

capping protein regulator and myosin 1 linker 2

involved_in

GO_REF:0000107

NCBI chr 6:28,265,130...28,277,649
Ensembl chr 6:28,264,320...28,279,703

CRACD

capping protein inhibiting regulator of actin dynamics

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 8:55,336,363...55,600,931
Ensembl chr 8:55,463,441...55,600,939

LOC100522401

WASH complex subunit 2A

involved_in

(PMID:20498093)

PMID:20498093

NCBI chr14:90,582,399...90,640,494

negative regulation of cardiac myofibril assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SMAD4

SMAD family member 4

involved_in

GO_REF:0000107

NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,514,791...100,628,029

negative regulation of centriole replication

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CDK5RAP2

CDK5 regulatory subunit associated protein 2

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 1:260,465,809...260,648,070
Ensembl chr 1:260,467,159...260,635,443

KAT2A

lysine acetyltransferase 2A

involved_in

GO_REF:0000107

NCBI chr12:20,638,493...20,647,464
Ensembl chr12:20,638,493...20,647,463

KAT2B

lysine acetyltransferase 2B

involved_in

GO_REF:0000107

NCBI chr13:6,985,151...7,099,771
Ensembl chr13:6,985,235...7,100,346

MDM1

Mdm1 nuclear protein

involved_in

GO_REF:0000002

NCBI chr 5:32,640,939...32,673,624
Ensembl chr 5:32,640,945...32,673,638

RBM14

RNA binding motif protein 14

involved_in

GO_REF:0000107

NCBI chr 2:5,791,445...5,800,784
Ensembl chr 2:5,759,062...5,800,832

TRIM37

tripartite motif containing 37

involved_in

Ensembl
Ensembl
GO_Central
GO_Central

(PMID:21873635)

GO_REF:0000107

NCBI chr12:35,259,292...35,393,464
Ensembl chr12:35,240,793...35,393,415

negative regulation of centrosome duplication

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCNF

cyclin F

involved_in
acts_upstream_of_or_within

(MGI:4819440|PMID:20596027)

PMID:20596027

GO_REF:0000107 MGI:4819440

NCBI chr 3:39,585,597...39,603,088
Ensembl chr 3:39,585,602...39,603,083

CENATAC

centrosomal AT-AC splicing factor

involved_in

GO_REF:0000107

NCBI chr 9:46,230,365...46,239,433
Ensembl chr 9:46,229,729...46,239,433

NPM1

nucleophosmin 1

involved_in

GO_REF:0000107

NCBI chr16:52,767,263...52,781,862
Ensembl chr16:52,765,296...52,781,740

NUBP1

NUBP iron-sulfur cluster assembly factor 1, cytosolic

involved_in
acts_upstream_of_or_within

(MGI:3625381|PMID:16638812), (MGI:5463135|PMID:23028652)

PMID:16638812 PMID:23028652

GO_REF:0000107 MGI:3625381 MGI:5463135

NCBI chr 3:32,311,774...32,340,120
Ensembl chr 3:32,311,779...32,340,034

TMEM67

transmembrane protein 67

involved_in

Ensembl
Ensembl
RGD

PMID:19515853

GO_REF:0000107 RGD:8554306

NCBI chr 4:42,878,249...42,931,106
Ensembl chr 4:42,878,254...42,931,121

negative regulation of cytoskeleton organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ESPN

espin

involved_in

(MGI:3688341|PMID:15190118)

PMID:15190118

MGI:3688341

NCBI chr 6:67,284,106...67,316,577
Ensembl chr 6:67,284,021...67,315,863

LOC100514494

schwannomin-interacting protein 1

involved_in

(PMID:25950943)

PMID:25950943

NCBI chr13:98,858,981...99,633,023

negative regulation of microtubule depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APC

APC regulator of WNT signaling pathway

involved_in
acts_upstream_of_or_within

PMID:16525027 PMID:17192415

(PMID:17192415)
(MGI:3656452|PMID:16525027)

InterPro
Ensembl
InterPro
MGI

GO_REF:0000002 GO_REF:0000107 MGI:3656452

NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,912

APC2

APC regulator of WNT signaling pathway 2

involved_in

(PMID:21873635)

NCBI chr 2:77,005,706...77,034,583
Ensembl chr 2:77,005,706...77,038,009

ARHGEF2

Rho/Rac guanine nucleotide exchange factor 2

involved_in

UniProt
UniProt
Ensembl
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:94,026,391...94,082,206
Ensembl chr 4:94,026,385...94,080,422

ATXN7

ataxin 7

involved_in

MGI
Ensembl
GO_Central
GO_Central

GO_REF:0000107

NCBI chr13:45,356,350...45,514,816
Ensembl chr13:45,401,127...45,498,067

BMERB1

bMERB domain containing 1

acts_upstream_of_or_within
involved_in

ISO
IEA
IBA

(MGI:5578117|PMID:25099998)
(PMID:21873635)

PMID:21873635 PMID:25099998

GO_REF:0000107 MGI:5578117

NCBI chr 3:7,248,806...7,387,523
Ensembl chr 3:7,248,826...7,387,813

CAMSAP1

calmodulin regulated spectrin associated protein 1

involved_in

(PMID:21873635)

calmodulin regulated spectrin associated protein family member 2

involved_in

(PMID:21873635)

NCBI chr10:23,275,302...23,360,167
Ensembl chr10:23,275,321...23,360,168

CAMSAP3

calmodulin regulated spectrin associated protein family member 3

involved_in

(PMID:21873635)

NCBI chr 2:71,531,607...71,547,413
Ensembl chr 2:71,531,607...71,547,419

CIB1

calcium and integrin binding 1

involved_in

GO_REF:0000107

NCBI chr 7:55,794,834...55,798,666
Ensembl chr 7:55,794,834...55,798,590

CKAP2

cytoskeleton associated protein 2

involved_in
acts_upstream_of_or_within

(MGI:3589528|PMID:16061649)

PMID:16061649

GO_REF:0000107 MGI:3589528

NCBI chr11:15,751,717...15,767,068
Ensembl chr11:15,751,801...15,766,497

CLASP1

cytoplasmic linker associated protein 1

involved_in
acts_upstream_of_or_within

(MGI:2176392|PMID:11290329)

PMID:11290329

GO_REF:0000107 MGI:2176392

NCBI chr15:29,782,613...30,042,727
Ensembl chr15:29,782,604...30,042,734

CLASP2

cytoplasmic linker associated protein 2

acts_upstream_of_or_within

PMID:11290329 PMID:17113391

(MGI:3693027|PMID:17113391)
(MGI:2176392|PMID:11290329)

RGD
MGI

MGI:2176392 MGI:3693027 RGD:68300

NCBI chr13:19,305,430...19,510,589
Ensembl chr13:19,305,180...19,510,585

EML4

EMAP like 4

acts_upstream_of_or_within

(MGI:3709709|PMID:17196341)

PMID:17196341

MGI:3709709

NCBI chr 3:98,005,809...98,155,876
Ensembl chr 3:98,005,811...98,155,831

FGF13

fibroblast growth factor 13

involved_in

(MGI:5431268|PMID:22726441)

PMID:22726441

MGI:5431268

NCBI chr X:113,460,191...113,955,691
Ensembl chr X:113,460,191...113,932,715

GAS2L1

growth arrest specific 2 like 1

involved_in

ISS

GO_REF:0000024

NCBI chr14:46,449,767...46,455,278
Ensembl chr14:46,449,787...46,455,276

GAS2L2

growth arrest specific 2 like 2

involved_in

(PMID:12584248)

PMID:12584248

NCBI chr12:39,772,070...39,785,159
Ensembl chr12:39,768,014...39,785,159

HDAC6

histone deacetylase 6

involved_in
acts_upstream_of_or_within

(MGI:2447264|PMID:12486003)

PMID:12486003

GO_REF:0000107 MGI:2447264

NCBI chr X:42,917,911...42,941,894
Ensembl chr X:42,917,960...42,941,890

HDGFL3

HDGF like 3

involved_in

GO_REF:0000107

NCBI chr 7:51,730,898...51,818,666
Ensembl chr 7:51,731,076...51,822,378

KATNB1

katanin regulatory subunit B1

involved_in

GO_REF:0000107

NCBI chr 6:19,630,355...19,659,039
Ensembl chr 6:19,630,350...19,667,676

MAP1A

microtubule associated protein 1A

NCBI chr 1:127,916,639...127,936,952
Ensembl chr 1:127,916,644...127,936,955

MAP1B

microtubule associated protein 1B

NCBI chr16:48,403,338...48,501,453
Ensembl chr16:48,403,526...48,498,896

MAP2

microtubule associated protein 2

involved_in

PMID:11029056

NCBI chr15:112,156,578...112,462,932
Ensembl chr15:112,156,578...112,460,171

MAP6D1

MAP6 domain containing 1

involved_in
acts_upstream_of_or_within

(MGI:3695226|PMID:16837464)

PMID:16837464

GO_REF:0000107 MGI:3695226

NCBI chr13:121,738,392...121,755,482
Ensembl chr13:121,740,454...121,755,480

MID1

midline 1

acts_upstream_of_or_within

(MGI:3046496|PMID:15070402)

PMID:15070402

MGI:3046496

NCBI chr X:7,235,386...7,906,049
Ensembl chr X:7,237,942...7,620,011

MID1IP1

MID1 interacting protein 1

involved_in
acts_upstream_of_or_within

(MGI:3046496|PMID:15070402)

PMID:15070402

GO_REF:0000107 MGI:3046496

NCBI chr X:34,763,360...34,766,160
Ensembl chr X:34,763,355...34,766,079

NAV3

neuron navigator 3

involved_in

GO_REF:0000107

NCBI chr 5:103,013,798...103,863,222
Ensembl chr 5:103,013,798...103,368,021

SPECC1L

sperm antigen with calponin homology and coiled-coil domains 1 like

acts_upstream_of_or_within

(MGI:5433266|PMID:21703590)

PMID:21703590

MGI:5433266

NCBI chr14:49,332,937...49,463,965

SPEF1

sperm flagellar 1

involved_in

GO_REF:0000107

NCBI chr17:31,934,856...31,938,463
Ensembl chr17:31,934,832...31,941,621

STMN2

stathmin 2

involved_in

GO_REF:0000107

NCBI chr 4:56,952,968...57,006,744
Ensembl chr 4:56,952,973...57,006,463

TAOK1

TAO kinase 1

involved_in

GO_REF:0000107

NCBI chr12:45,597,067...45,750,117
Ensembl chr12:45,597,057...45,744,356

TPX2

TPX2 microtubule nucleation factor

involved_in

GO_REF:0000107

NCBI chr17:35,431,271...35,484,814
Ensembl chr17:35,431,370...35,484,760

TRIM54

tripartite motif containing 54

acts_upstream_of_or_within

(MGI:1888564|PMID:10953002)

PMID:10953002

MGI:1888564

NCBI chr 3:111,836,038...111,852,468
Ensembl chr 3:111,834,151...111,852,745

TTBK2

tau tubulin kinase 2

involved_in

GO_REF:0000107

NCBI chr 1:128,489,676...128,640,094
Ensembl chr 1:128,489,687...128,635,527

negative regulation of microtubule nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARHGEF7

Rho guanine nucleotide exchange factor 7

involved_in

(PMID:27012601)

PMID:27012601

NCBI chr11:77,427,352...77,531,001
Ensembl chr11:77,427,368...77,530,995

negative regulation of microtubule polymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAPZB

capping actin protein of muscle Z-line subunit beta

acts_upstream_of_or_within

(MGI:4397629|PMID:19806181)

PMID:19806181

MGI:4397629

NCBI chr 6:77,780,682...77,912,653
Ensembl chr 6:77,780,681...77,912,617

CDH5

cadherin 5

involved_in

GO_REF:0000107

NCBI chr 6:27,108,560...27,142,145
Ensembl chr 6:27,108,609...27,142,180

CLIP3

CAP-Gly domain containing linker protein 3

involved_in

GO_REF:0000107

NCBI chr 6:45,390,656...45,418,866
Ensembl chr 6:45,390,658...45,418,873

DYRK1A

dual specificity tyrosine phosphorylation regulated kinase 1A

involved_in

GO_REF:0000107

NCBI chr13:201,008,506...201,159,946
Ensembl chr13:201,008,830...201,159,954

EML2

EMAP like 2

involved_in

InterPro
InterPro
Ensembl
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr 6:51,988,084...52,013,394
Ensembl chr 6:51,983,955...52,013,393

FKBP4

FKBP prolyl isomerase 4

NCBI chr 5:67,314,010...67,321,628
Ensembl chr 5:67,313,475...67,322,029

INPP5J

inositol polyphosphate-5-phosphatase J

NCBI chr14:47,912,921...47,922,632
Ensembl chr14:47,913,405...47,927,112

MAP2

microtubule associated protein 2

involved_in

PMID:28426968

NCBI chr15:112,156,578...112,462,932
Ensembl chr15:112,156,578...112,460,171

MAPRE1

microtubule associated protein RP/EB family member 1

involved_in

Ensembl
UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr17:36,390,698...36,426,435
Ensembl chr17:36,387,062...36,487,494

SGK1

serum/glucocorticoid regulated kinase 1

NCBI chr 1:29,625,786...29,753,619
Ensembl chr 1:29,625,781...29,753,607

SNCA

synuclein alpha

involved_in

GO_REF:0000107

NCBI chr 8:129,247,724...129,388,307
Ensembl chr 8:129,248,819...129,388,307

STMN1

stathmin 1

involved_in
acts_upstream_of_or_within

(MGI:3529385|PMID:15652749)

PMID:15652749

GO_REF:0000107 MGI:3529385

NCBI chr 6:83,356,404...83,362,546
Ensembl chr 6:83,356,411...83,362,500

STMN2

stathmin 2

involved_in

GO_REF:0000107

NCBI chr 4:56,952,968...57,006,744
Ensembl chr 4:56,952,973...57,006,463

TBCD

tubulin folding cofactor D

involved_in

GO_REF:0000107

NCBI chr12:327,009...449,375
Ensembl chr12:327,013...449,557

TUBB4A

tubulin beta 4A class IVa

involved_in

GO_REF:0000107

NCBI chr 2:72,599,244...72,605,362
Ensembl chr 2:72,599,706...72,619,450

negative regulation of microtubule polymerization or depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CLASP1

cytoplasmic linker associated protein 1

involved_in

(PMID:12837247)

PMID:12837247

NCBI chr15:29,782,613...30,042,727
Ensembl chr15:29,782,604...30,042,734

negative regulation of sarcomere organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAV3

caveolin 3

involved_in

GO_REF:0000107

NCBI chr13:65,117,868...65,130,886
Ensembl chr13:65,117,776...65,134,066

mitofusin 2

NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,026,722...72,056,439

negative regulation of stress fiber assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

involved_in

GO_REF:0000107

NCBI chr 9:7,238,043...7,301,085
Ensembl chr 9:7,233,911...7,301,086

ARHGAP28

Rho GTPase activating protein 28

involved_in
acts_upstream_of_or_within

GO_Central
GO_Central
Ensembl
MGI

(PMID:21873635)
(MGI:5644775|PMID:25211221)

PMID:21873635 PMID:25211221

GO_REF:0000107 MGI:5644775

NCBI chr 6:100,494,385...100,681,008
Ensembl chr 6:100,493,261...100,655,708

ARHGAP6

Rho GTPase activating protein 6

involved_in

GO_REF:0000107

NCBI chr X:7,910,851...8,441,579
Ensembl chr X:7,910,858...8,120,386

ARHGEF18

Rho/Rac guanine nucleotide exchange factor 18

involved_in

GO_REF:0000107

NCBI chr 2:71,651,096...71,747,513
Ensembl chr 2:71,651,100...71,747,410

CGNL1

cingulin like 1

involved_in

GO_REF:0000107

NCBI chr 1:114,424,148...114,628,331
Ensembl chr 1:114,424,157...114,598,823

CLASP1

cytoplasmic linker associated protein 1

involved_in

GO_REF:0000107

NCBI chr15:29,782,613...30,042,727
Ensembl chr15:29,782,604...30,042,734

CLASP2

cytoplasmic linker associated protein 2

involved_in

(PMID:24859005)

PMID:24859005

NCBI chr13:19,305,430...19,510,589
Ensembl chr13:19,305,180...19,510,585

CORO2B

coronin 2B

involved_in
acts_upstream_of_or_within

(MGI:6110508|PMID:29162887)

PMID:29162887

GO_REF:0000107 MGI:6110508

NCBI chr 1:166,465,870...166,608,840
Ensembl chr 1:166,465,953...166,608,367

DLC1

DLC1 Rho GTPase activating protein

involved_in

GO_REF:0000107

NCBI chr17:1,169,709...1,637,171
Ensembl chr17:1,170,195...1,637,162

F11 receptor

involved_in

GO_REF:0000107

NCBI chr 4:89,425,101...89,447,889
Ensembl chr 4:89,425,039...89,449,932

FRMD7

FERM domain containing 7

involved_in
acts_upstream_of_or_within

(MGI:5546532|PMID:23967341)

PMID:23967341

GO_REF:0000107 MGI:5546532

NCBI chr X:108,241,116...108,294,188
Ensembl chr X:108,241,135...108,294,123

INPP5K

inositol polyphosphate-5-phosphatase K

involved_in

Ensembl
UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr12:47,717,898...47,738,540
Ensembl chr12:47,717,907...47,738,477

MET

MET proto-oncogene, receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,044...29,541,512

MIR138

microRNA mir-138

involved_in

(PMID:20232393)

PMID:20232393

NCBI chr13:27,450,130...27,450,214
Ensembl chr13:27,450,130...27,450,214

MIR20A

microRNA mir-20a

involved_in

(PMID:22696064)

PMID:22696064

NCBI chr11:60,735,109...60,735,179
Ensembl chr11:60,735,099...60,735,196

MIR21

microRNA mir-21

involved_in

(PMID:21347332)

PMID:21347332

NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358

MYOC

myocilin

involved_in

GO_REF:0000107

NCBI chr 9:114,087,370...114,098,765
Ensembl chr 9:114,087,374...114,098,743

PAK2

p21 (RAC1) activated kinase 2

involved_in

GO_REF:0000107

NCBI chr13:133,276,122...133,383,506
Ensembl chr13:133,283,300...133,496,071

profilin 1

involved_in

(PMID:23153535)

NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,696...51,973,660

PHLDB2

pleckstrin homology like domain family B member 2

involved_in

GO_REF:0000107

NCBI chr13:147,778,420...148,025,943
Ensembl chr13:147,778,053...148,087,744

PHLDB2

pleckstrin homology like domain family B member 2

involved_in

GO_REF:0000107

NCBI chr13:148,033,712...148,087,766
Ensembl chr13:147,778,053...148,087,744

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

involved_in

GO_REF:0000107

NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,434,873...46,523,609

PPFIA1

PTPRF interacting protein alpha 1

involved_in
acts_upstream_of_or_within

(PMID:22266902)
(MGI:5492034|PMID:22266902)

PMID:22266902

GO_REF:0000107 MGI:5492034

NCBI chr 2:3,073,236...3,165,476
Ensembl chr 2:3,073,236...3,164,038

PPP1R9A

protein phosphatase 1 regulatory subunit 9A

NCBI chr 9:74,635,285...74,944,050
Ensembl chr 9:74,635,280...74,940,362

RHPN1

rhophilin Rho GTPase binding protein 1

acts_upstream_of_or_within
involved_in

PMID:21873635 PMID:25071083

(MGI:6316493|PMID:25071083)
(PMID:21873635)

MGI
GO_Central

MGI:6316493

NCBI chr 4:1,123,098...1,133,030
Ensembl chr 4:1,123,101...1,132,966

RHPN2

rhophilin Rho GTPase binding protein 2

acts_upstream_of_or_within
involved_in

ISO
IBA
IEA

(PMID:25071083)
(PMID:21873635)

MGI
GO_Central
Ensembl
Ensembl

PMID:21873635 PMID:25071083

GO_REF:0000107

NCBI chr 6:42,820,564...42,891,340
Ensembl chr 6:42,820,568...42,891,346

S1PR1

sphingosine-1-phosphate receptor 1

NCBI chr 4:117,064,632...117,069,724
Ensembl chr 4:117,064,724...117,069,649

STMN1

stathmin 1

involved_in

GO_REF:0000107

NCBI chr 6:83,356,404...83,362,546
Ensembl chr 6:83,356,411...83,362,500

TACSTD2

tumor associated calcium signal transducer 2

involved_in

ISS

GO_REF:0000024

NCBI chr 6:153,859,488...153,861,508
Ensembl chr 6:153,859,482...153,861,492

TJP1

tight junction protein 1

involved_in

GO_REF:0000107

NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,368...145,195,836

TMEFF2

transmembrane protein with EGF like and two follistatin like domains 2

acts_upstream_of_or_within
involved_in

(PMID:24632071)

PMID:24632071

GO_REF:0000107

NCBI chr15:96,594,901...96,856,848
Ensembl chr15:96,594,962...96,855,745

WAS

WASP actin nucleation promoting factor

involved_in

GO_REF:0000107

NCBI chr X:42,774,597...42,793,055
Ensembl chr X:42,774,588...42,793,055

WASF2

WASP family member 2

involved_in

GO_REF:0000107

NCBI chr 6:84,621,742...84,697,428
Ensembl chr 6:84,622,775...84,697,429

pointed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LMOD1

leiomodin 1

involved_in

GO_REF:0000002

NCBI chr10:24,165,293...24,194,823
Ensembl chr10:24,164,792...24,193,820

LMOD2

leiomodin 2

involved_in

GO_REF:0000002

NCBI chr18:23,803,927...23,815,772
Ensembl chr18:23,803,661...23,812,481

NCBP1

nuclear cap binding protein subunit 1

involved_in

GO_REF:0000002

NCBI chr 1:239,492,573...239,543,925
Ensembl chr 1:239,374,934...239,543,585

NCBP1

nuclear cap binding protein subunit 1

involved_in

GO_REF:0000002

NCBI chr 1:239,375,150...239,468,387
Ensembl chr 1:239,374,934...239,543,585

TMOD2

tropomodulin 2

involved_in

GO_REF:0000002

NCBI chr 1:119,956,583...120,009,372
Ensembl chr 1:119,956,588...120,009,364

TMOD3

tropomodulin 3

involved_in

GO_REF:0000002

NCBI chr 1:119,864,878...119,948,795
Ensembl chr 1:119,862,244...119,948,883

TMOD4

tropomodulin 4

involved_in

GO_REF:0000002

NCBI chr 4:98,074,380...98,079,346
Ensembl chr 4:98,074,496...98,079,343

positive regulation of actin cytoskeleton reorganization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,711

ACTR3

actin related protein 3

NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,846...20,208,186

actin related protein 2/3 complex subunit 2

NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059

BAIAP2

BAR/IMD domain containing adaptor protein 2

involved_in

(PMID:21873635)

NCBI chr12:1,609,420...1,666,965
Ensembl chr12:1,603,538...1,670,076

BAIAP2L1

BAR/IMD domain containing adaptor protein 2 like 1

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 3:5,472,305...5,567,926
Ensembl chr 3:5,472,315...5,567,876

BAIAP2L2

BAR/IMD domain containing adaptor protein 2 like 2

involved_in

(PMID:21873635)

NCBI chr 5:9,778,643...9,799,705
Ensembl chr 5:9,778,727...9,799,703

BCAS3

BCAS3 microtubule associated cell migration factor

involved_in

(MGI:5582152|PMID:22300583)

GO_Central
GO_Central
MGI

PMID:22300583

MGI:5582152

NCBI chr12:36,894,727...37,475,221
Ensembl chr12:36,895,053...37,475,187

CCL27

C-C motif chemokine ligand 27

involved_in
acts_upstream_of_or_within

IBA
ISO

(PMID:21873635)
(MGI:5515359|PMID:12133963)

PMID:12133963 PMID:21873635

MGI:5515359

NCBI chr10:32,138,232...32,138,980
Ensembl chr10:32,138,232...32,138,974

CDC42

cell division cycle 42

involved_in

GO_REF:0000107

NCBI chr 6:80,035,034...80,089,243
Ensembl chr 6:80,035,122...80,089,233

CSF3

colony stimulating factor 3

involved_in

GO_REF:0000107

NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,445...22,342,163

FES

FES proto-oncogene, tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 7:53,472,947...53,485,084
Ensembl chr 7:53,472,946...53,485,082

HAX1

HCLS1 associated protein X-1

involved_in

GO_REF:0000107

NCBI chr 4:95,467,629...95,470,972
Ensembl chr 4:95,467,629...95,470,288

HCK

HCK proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr17:35,708,549...35,751,590
Ensembl chr17:35,709,348...35,751,588

HRAS

HRas proto-oncogene, GTPase

involved_in

GO_REF:0000107

NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501

NRP1

neuropilin 1

involved_in

GO_REF:0000107

NCBI chr10:56,280,673...56,430,832
Ensembl chr10:56,280,363...56,430,777

NTF3

neurotrophin 3

involved_in

GO_REF:0000107

NCBI chr 5:65,052,608...65,122,645
Ensembl chr 5:65,052,517...65,123,788

NTRK3

neurotrophic receptor tyrosine kinase 3

involved_in

GO_REF:0000107

NCBI chr 1:191,535,262...191,941,675
Ensembl chr 1:191,535,300...191,925,353

RAPGEF3

Rap guanine nucleotide exchange factor 3

NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,289...78,134,103

STAP1

signal transducing adaptor family member 1

involved_in

GO_REF:0000107

NCBI chr 8:65,318,861...65,372,838
Ensembl chr 8:65,332,522...65,392,965

TEK

TEK receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 1:195,938,177...196,052,294
Ensembl chr 1:195,937,394...196,051,957

positive regulation of actin filament bundle assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CX3CL1

C-X3-C motif chemokine ligand 1

involved_in

(PMID:10415068)

PMID:10415068

NCBI chr 6:19,312,351...19,324,439

filamin A

NCBI chr X:124,889,934...124,915,000
Ensembl chr X:124,890,142...124,917,171

ID1

inhibitor of DNA binding 1, HLH protein

NCBI chr17:35,316,518...35,317,742
Ensembl chr17:35,315,964...35,317,744

LIMK1

LIM domain kinase 1

involved_in

GO_REF:0000107

NCBI chr 3:11,252,820...11,279,286
Ensembl chr 3:11,252,645...11,279,285

MTSS1

MTSS I-BAR domain containing 1

acts_upstream_of_or_within
involved_in

MGI
GO_Central
GO_Central

(MGI:5317250|PMID:21406566)
(PMID:21873635)

PMID:21406566 PMID:21873635

MGI:5317250

NCBI chr 4:14,933,290...15,103,256
Ensembl chr 4:14,933,324...15,105,406

profilin 2

involved_in

(PMID:21873635)

NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742

PLEK

pleckstrin

involved_in

GO_REF:0000107

NCBI chr 3:73,877,741...73,910,163
Ensembl chr 3:73,877,743...74,005,519

SWAP70

switching B cell complex subunit SWAP70

involved_in

GO_REF:0000107

NCBI chr 2:49,721,120...49,805,262
Ensembl chr 2:49,719,669...49,804,883

SYNPO

synaptopodin

involved_in

InterPro
InterPro
GO_Central
GO_Central

(PMID:21873635)

GO_REF:0000002

NCBI chr 2:151,571,264...151,634,103
Ensembl chr 2:151,585,274...151,632,099

SYNPO2

synaptopodin 2

involved_in

(PMID:21873635)

NCBI chr 8:104,677,580...104,844,169
Ensembl chr 8:104,677,580...104,873,791

SYNPO2L

synaptopodin 2 like

involved_in

(PMID:21873635)

NCBI chr14:76,456,170...76,466,661
Ensembl chr14:76,456,167...76,473,423

villin 1

involved_in

Ensembl
Ensembl
UniProt
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580

positive regulation of actin filament depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CFL1

cofilin 1

involved_in
acts_upstream_of_or_within

PMID:15548599 PMID:23921380

(MGI:5554982|PMID:23921380)
(MGI:3575233|PMID:15548599)

CACAO
MGI

MGI:3575233 MGI:5554982

NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035

CFL2

cofilin 2

involved_in

GO_REF:0000107

NCBI chr 7:65,090,170...65,094,521
Ensembl chr 7:65,090,277...65,094,519

DSTN

destrin, actin depolymerizing factor

involved_in
acts_upstream_of_or_within

ISS
IEA
ISO

(MGI:3575233|PMID:15548599)

AgBase
Ensembl
InterPro
AgBase
MGI
Ensembl
InterPro

PMID:15548599

GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:3575233

NCBI chr17:25,998,830...26,050,354
Ensembl chr17:25,998,125...26,050,354

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000107

NCBI chr 2:85,732,082...85,747,552
Ensembl chr 2:85,732,189...85,750,858

PDXP

pyridoxal phosphatase

involved_in

GO_REF:0000107

NCBI chr 5:10,162,642...10,169,726
Ensembl chr 5:10,162,642...10,169,512

PLEK

pleckstrin

involved_in

GO_REF:0000107

NCBI chr 3:73,877,741...73,910,163
Ensembl chr 3:73,877,743...74,005,519

SEMA5A

semaphorin 5A

involved_in

(MGI:5526935|PMID:19850054)

PMID:19850054

MGI:5526935

NCBI chr16:72,796,453...73,335,974
Ensembl chr16:72,492,516...73,329,010

villin 1

involved_in

GO_REF:0000107

NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580

WDR1

WD repeat domain 1

involved_in
acts_upstream_of_or_within

GO_Central
Ensembl
GO_Central
MGI

(PMID:21873635)
(MGI:5574550|PMID:24840128)

PMID:21873635 PMID:24840128

GO_REF:0000107 MGI:5574550

NCBI chr 8:6,413,338...6,452,383
Ensembl chr 8:6,413,347...6,452,346

positive regulation of actin filament polymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTR3

actin related protein 3

NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,846...20,208,186

ALOX12

arachidonate 12-lipoxygenase, 12S type

involved_in

GO_REF:0000107

NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,286,019...52,414,907

ALOX15

arachidonate 15-lipoxygenase

involved_in

Ensembl
UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr12:52,287,174...52,295,873
Ensembl chr12:52,286,019...52,414,907

ARF6

ADP ribosylation factor 6

involved_in

GO_REF:0000107

NCBI chr 1:179,697,582...179,717,299
Ensembl chr 1:179,697,615...179,717,844

actin related protein 2/3 complex subunit 2

acts_upstream_of_or_within
involved_in

(MGI:3818245|PMID:18836449)

PMID:18836449

GO_REF:0000107 MGI:3818245

NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059

BAG4

BAG cochaperone 4

involved_in

GO_REF:0000107

NCBI chr15:48,299,456...48,348,810
Ensembl chr15:48,299,662...48,348,527

BAIAP2

BAR/IMD domain containing adaptor protein 2

involved_in

(PMID:21873635)

NCBI chr12:1,609,420...1,666,965
Ensembl chr12:1,603,538...1,670,076

BAIAP2L1

BAR/IMD domain containing adaptor protein 2 like 1

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 3:5,472,305...5,567,926
Ensembl chr 3:5,472,315...5,567,876

BAIAP2L2

BAR/IMD domain containing adaptor protein 2 like 2

involved_in

(PMID:21873635)

NCBI chr 5:9,778,643...9,799,705
Ensembl chr 5:9,778,727...9,799,703

BIN1

bridging integrator 1

involved_in

GO_REF:0000107

NCBI chr15:25,328,679...25,379,675
Ensembl chr15:25,328,674...25,383,652

capping protein regulator and myosin 1 linker 1

involved_in

GO_REF:0000107

NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,739...20,353,431

CCL11

chemokine (C-C motif) ligand 11

involved_in

GO_REF:0000107

NCBI chr12:40,779,906...40,782,862
Ensembl chr12:40,779,173...40,782,893

CCL21

C-C motif chemokine ligand 21

involved_in

GO_REF:0000107

NCBI chr10:32,093,783...32,094,482
Ensembl chr10:31,933,733...32,094,583

CCL24

C-C motif chemokine ligand 24

involved_in

(PMID:19525930)

PMID:19525930

NCBI chr 3:10,347,397...10,361,500

CCL26

C-C motif chemokine ligand 26

involved_in

GO_REF:0000107

NCBI chr 3:10,381,306...10,385,677
Ensembl chr 3:10,381,296...10,385,796

CCL8

chemokine (C-C motif) ligand 8

involved_in

GO_REF:0000107

NCBI chr12:40,740,468...40,741,970
Ensembl chr12:40,740,023...40,742,022

CDC42EP1

CDC42 effector protein 1

involved_in

(PMID:21873635)

NCBI chr 5:10,244,625...10,253,430
Ensembl chr 5:10,240,697...10,252,988

CDC42EP2

CDC42 effector protein 2

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 2:6,897,497...6,904,040
Ensembl chr 2:6,895,817...6,904,040

CDC42EP3

CDC42 effector protein 3

involved_in

(PMID:21873635)

NCBI chr 3:102,537,662...102,567,669
Ensembl chr 3:102,538,586...102,567,814

CDC42EP4

CDC42 effector protein 4

involved_in

(PMID:21873635)

NCBI chr12:7,637,797...7,660,189
Ensembl chr12:7,638,085...7,660,188

CDC42EP5

CDC42 effector protein 5

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 6:58,852,426...58,857,622
Ensembl chr 6:58,857,090...58,857,551

CRACD

capping protein inhibiting regulator of actin dynamics

involved_in

GO_REF:0000107

NCBI chr 8:55,336,363...55,600,931
Ensembl chr 8:55,463,441...55,600,939

CSF3

colony stimulating factor 3

involved_in

GO_REF:0000107

NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,445...22,342,163

CTTN

cortactin

involved_in

GO_REF:0000107

NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,102...3,060,855

DLG1

discs large MAGUK scaffold protein 1

involved_in
acts_upstream_of_or_within

(MGI:3528803|PMID:15699074)

PMID:15699074

GO_REF:0000107 MGI:3528803

NCBI chr13:132,819,931...133,084,880
Ensembl chr13:132,820,870...133,086,843

EVL

Enah/Vasp-like

involved_in

(PMID:21873635)

NCBI chr 7:120,911,814...121,056,556
Ensembl chr 7:120,911,220...121,056,558

FCHSD1

FCH and double SH3 domains 1

involved_in

GO_REF:0000107

NCBI chr 2:143,289,854...143,301,921
Ensembl chr 2:143,289,859...143,304,416

FCHSD2

FCH and double SH3 domains 2

involved_in

GO_REF:0000107

NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,521...7,619,926

FER

FER tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 2:113,774,120...114,207,307
Ensembl chr 2:113,774,412...114,206,930

FMN1

formin 1

acts_upstream_of_or_within

(MGI:3027450|PMID:14647292)

PMID:14647292

MGI:3027450

NCBI chr 1:136,696,353...137,163,532
Ensembl chr 1:136,704,090...137,008,721

GCHFR

GTP cyclohydrolase I feedback regulator

involved_in

(PMID:21873635)

NCBI chr 1:130,559,223...130,563,598
Ensembl chr 1:130,554,976...130,563,562

GRB2

growth factor receptor bound protein 2

involved_in
acts_upstream_of_or_within

(MGI:3768467|PMID:17923684)

PMID:17923684

GO_REF:0000107 MGI:3768467

NCBI chr12:5,940,723...6,009,095
Ensembl chr12:5,940,647...6,010,835

ICAM1

intercellular adhesion molecule 1

NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205

KIRREL1

kirre like nephrin family adhesion molecule 1

acts_upstream_of_or_within

(MGI:3768467|PMID:17923684)

PMID:17923684

MGI:3768467

NCBI chr 4:92,173,897...92,290,887
Ensembl chr 4:92,176,745...92,290,610

LMOD1

leiomodin 1

involved_in

GO_REF:0000107

NCBI chr10:24,165,293...24,194,823
Ensembl chr10:24,164,792...24,193,820

LMOD2

leiomodin 2

involved_in

GO_REF:0000107

NCBI chr18:23,803,927...23,815,772
Ensembl chr18:23,803,661...23,812,481

LOC100522011

apoptosis-associated speck-like protein containing a CARD

involved_in

GO_REF:0000107

NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,179...17,307,512

MAP3K1

mitogen-activated protein kinase kinase kinase 1

acts_upstream_of_or_within

(MGI:2674169|PMID:12941696), (MGI:5608927|PMID:25224220)

PMID:12941696 PMID:25224220

MGI:2674169 MGI:5608927

NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,871,799...35,946,987

MLST8

MTOR associated protein, LST8 homolog

involved_in
acts_upstream_of_or_within

(MGI:3510095|PMID:15467718)

GO_REF:0000107 MGI:3510095

NCBI chr 3:39,778,746...39,786,206
Ensembl chr 3:39,778,754...39,788,309

MTOR

mechanistic target of rapamycin kinase

involved_in
acts_upstream_of_or_within

(MGI:3510095|PMID:15467718)

GO_REF:0000107 MGI:3510095

NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888

myosin IC

NCBI chr12:47,691,252...47,715,670
Ensembl chr12:47,691,252...47,738,439

NCK1

NCK adaptor protein 1

involved_in
acts_upstream_of_or_within

(MGI:3768467|PMID:17923684)

UniProt
MGI
UniProt
Ensembl

PMID:17923684

GO_REF:0000104 GO_REF:0000107 MGI:3768467

NCBI chr13:77,863,655...77,940,944
Ensembl chr13:77,863,701...77,986,156

NCK1

NCK adaptor protein 1

involved_in

Ensembl
UniProt

GO_REF:0000104 GO_REF:0000107

NCBI chr13:77,946,356...77,986,158
Ensembl chr13:77,863,701...77,986,156

NCK2

NCK adaptor protein 2

involved_in

UniProt
UniProt
Ensembl

GO_REF:0000104 GO_REF:0000107

NCBI chr 3:49,063,813...49,222,274
Ensembl chr 3:49,063,988...49,198,664

NCKAP1

NCK associated protein 1

involved_in

(MGI:5897521|PMID:27927633)

PMID:27927633

MGI:5897521

NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,141...88,528,231

NCKAP1L

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132

NPHS1

NPHS1 adhesion molecule, nephrin

involved_in

GO_REF:0000107

NCBI chr 6:45,248,325...45,271,892
Ensembl chr 6:45,248,317...45,271,550

profilin 1

involved_in

(PMID:23153535)

NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,696...51,973,660

profilin 2

acts_upstream_of_or_within
involved_in

PMID:17541406 PMID:23153535

(MGI:3714870|PMID:17541406)
(PMID:23153535)

MGI
UniProt

MGI:3714870

NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742

PRKCE

protein kinase C epsilon

involved_in

GO_REF:0000107

NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,909,020

PTK2B

protein tyrosine kinase 2 beta

involved_in

GO_REF:0000107

NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,194

Rac family small GTPase 1

acts_upstream_of_or_within

(MGI:2668778|PMID:12853475)

PMID:12853475

MGI:2668778

NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,771...4,803,687

RHOA

ras homolog family member A

involved_in

ISS
ISO

AgBase
AgBase
RGD

PMID:17369454

GO_REF:0000024 RGD:1642965

NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,836...32,003,722

RICTOR

RPTOR independent companion of MTOR complex 2

involved_in
acts_upstream_of_or_within

(MGI:3510095|PMID:15467718)

GO_REF:0000107 MGI:3510095

NCBI chr16:24,109,934...24,250,019
Ensembl chr16:24,109,934...24,311,231

SNX9

sorting nexin 9

involved_in

GO_REF:0000107

NCBI chr 1:9,130,360...9,239,023
Ensembl chr 1:9,130,334...9,239,343

TENM1

teneurin transmembrane protein 1

involved_in

(MGI:5465054|PMID:22698694)

PMID:22698694

MGI:5465054

NCBI chr X:101,853,340...102,641,299
Ensembl chr X:101,856,938...102,411,207

VASP

vasodilator stimulated phosphoprotein

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 6:51,872,810...51,886,729
Ensembl chr 6:51,872,812...51,886,830

positive regulation of actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FMN1

formin 1

acts_upstream_of_or_within

(MGI:3027450|PMID:14647292)

PMID:14647292

MGI:3027450

NCBI chr 1:136,696,353...137,163,532
Ensembl chr 1:136,704,090...137,008,721

gelsolin

involved_in

GO_REF:0000107

NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287

MAGEL2

MAGE family member L2

involved_in
acts_upstream_of_or_within

(MGI:5603599|PMID:23452853)

PMID:23452853

GO_REF:0000107 MGI:5603599

NCBI chr 1:142,450,414...142,454,633
Ensembl chr 1:142,448,689...142,454,697

SCIN

scinderin

involved_in

GO_REF:0000107

NCBI chr 9:82,103,271...82,185,254
Ensembl chr 9:82,103,087...82,363,745

TRIM27

tripartite motif containing 27

acts_upstream_of_or_within

(MGI:5603599|PMID:23452853)

WASP homolog associated with actin, golgi membranes and microtubules

involved_in

GO_REF:0000107

NCBI chr 7:52,108,867...52,140,333
Ensembl chr 7:52,108,868...52,140,302

positive regulation of Arp2/3 complex-mediated actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABI2

abl interactor 2

involved_in

(PMID:21107423)

PMID:21107423

NCBI chr15:106,776,627...106,903,889
Ensembl chr15:106,776,625...106,900,334

BRK1

BRICK1 subunit of SCAR/WAVE actin nucleating complex

involved_in

GO_REF:0000107

NCBI chr13:66,315,438...66,324,641
Ensembl chr13:66,315,433...66,324,174

CYFIP1

cytoplasmic FMR1 interacting protein 1

involved_in

(PMID:21107423)

PMID:21107423

NCBI chr15:32,064,431...32,175,095

FCHSD2

FCH and double SH3 domains 2

involved_in

GO_REF:0000107

NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,521...7,619,926

LOC110256054

wiskott-Aldrich syndrome protein family member 1-like

involved_in

(PMID:21873635)

NCBI chr12:41,049,943...41,076,524

NCKAP1

NCK associated protein 1

involved_in

GO_REF:0000107

NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,141...88,528,231

WAS

WASP actin nucleation promoting factor

involved_in

GO_REF:0000002

NCBI chr X:42,774,597...42,793,055
Ensembl chr X:42,774,588...42,793,055

WASF1

WASP family member 1

involved_in

(PMID:21873635)

NCBI chr 1:76,107,595...76,180,335

WASF2

WASP family member 2

involved_in

(PMID:21873635)

NCBI chr 6:84,621,742...84,697,428
Ensembl chr 6:84,622,775...84,697,429

WASF3

WASP family member 3

involved_in

(PMID:21873635)

NCBI chr11:4,261,121...4,366,258
Ensembl chr11:4,261,177...4,366,254

WASL

WASP like actin nucleation promoting factor

involved_in

GO_REF:0000002

NCBI chr18:23,722,188...23,789,516
Ensembl chr18:23,722,188...23,789,506

positive regulation of barbed-end actin filament capping

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

actin related protein 2/3 complex subunit 2

NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059

cofilin 1

NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035

positive regulation of centriole elongation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CENPJ

centromere protein J

involved_in

GO_REF:0000107

NCBI chr11:289,660...357,920
Ensembl chr11:289,653...357,155

CEP120

centrosomal protein 120

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 2:126,840,262...126,930,117
Ensembl chr 2:126,838,294...126,930,483

CEP295

centrosomal protein 295

involved_in

GO_REF:0000107

NCBI chr 9:26,103,267...26,155,067
Ensembl chr 9:26,103,283...26,158,759

PPP1R35

protein phosphatase 1 regulatory subunit 35

involved_in

GO_REF:0000107

NCBI chr 3:8,363,005...8,378,351
Ensembl chr 3:8,363,008...8,376,045

VPS4B

vacuolar protein sorting 4 homolog B

involved_in

GO_REF:0000107

NCBI chr 1:158,233,039...158,273,533
Ensembl chr 1:158,233,051...158,270,679

positive regulation of centriole replication

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CENPJ

centromere protein J

involved_in

GO_REF:0000107

NCBI chr11:289,660...357,920
Ensembl chr11:289,653...357,155

HSPA4L

heat shock protein family A (Hsp70) member 4 like

involved_in

GO_REF:0000107

NCBI chr 8:97,032,179...97,088,240
Ensembl chr 8:96,991,940...97,090,023

NUP62

nucleoporin 62

involved_in

GO_REF:0000107

NCBI chr 6:54,921,627...54,945,705
Ensembl chr 6:54,921,627...54,923,227

PLK4

polo like kinase 4

involved_in
acts_upstream_of_or_within

(PMID:22349705)

Ensembl
MGI
Ensembl

PMID:22349705

GO_REF:0000107

NCBI chr 8:96,989,011...97,013,324
Ensembl chr 8:96,991,940...97,090,023

SASS6

SAS-6 centriolar assembly protein

involved_in

GO_REF:0000107

NCBI chr 4:117,985,599...118,049,129
Ensembl chr 4:117,985,142...118,050,047

STIL

STIL centriolar assembly protein

involved_in

GO_REF:0000107

NCBI chr 6:164,197,511...164,266,615
Ensembl chr 6:164,197,558...164,266,919

positive regulation of cytoskeleton organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adducin 3

NCBI chr14:120,451,421...120,583,725
Ensembl chr14:120,451,573...120,583,723

KATNBL1

katanin regulatory subunit B1 like 1

involved_in

GO_REF:0000107

NCBI chr 7:80,287,989...80,383,036
Ensembl chr 7:80,288,066...80,383,040

P2RX7

purinergic receptor P2X 7

involved_in

PMID:12857854

NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,192...31,476,472

PFDN2

prefoldin subunit 2

involved_in

GO_REF:0000107

NCBI chr 4:89,326,781...89,341,608
Ensembl chr 4:89,323,635...89,341,447

PLXNA3

plexin A3

involved_in

GO_REF:0000107

NCBI chr X:124,982,307...124,997,098
Ensembl chr X:124,984,190...124,997,067

positive regulation of intermediate filament depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NES

nestin

involved_in

(PMID:21873635)

NCBI chr 4:93,412,660...93,421,899
Ensembl chr 4:93,412,557...93,421,895

positive regulation of microtubule depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HTR1A

5-hydroxytryptamine receptor 1A

NCBI chr16:42,479,812...42,484,365

KATNB1

katanin regulatory subunit B1

involved_in

UniProt
Ensembl
UniProt

GO_REF:0000104 GO_REF:0000107

NCBI chr 6:19,630,355...19,659,039
Ensembl chr 6:19,630,350...19,667,676

SPAST

spastin

involved_in

GO_REF:0000104

NCBI chr 3:107,439,810...107,508,915
Ensembl chr 3:107,439,810...107,508,927

STMN2

stathmin 2

involved_in

GO_REF:0000107

NCBI chr 4:56,952,968...57,006,744
Ensembl chr 4:56,952,973...57,006,463

TRPV4

transient receptor potential cation channel subfamily V member 4

involved_in

PMID:20657843

NCBI chr14:41,125,819...41,169,582
Ensembl chr14:41,125,869...41,169,582

positive regulation of microtubule nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CKAP5

cytoskeleton associated protein 5

involved_in

GO_REF:0000107

NCBI chr 2:15,680,723...15,790,580
Ensembl chr 2:15,680,787...15,792,633

DCTN1

dynactin subunit 1

involved_in

GO_REF:0000107

NCBI chr 3:68,642,562...68,673,605
Ensembl chr 3:68,643,247...68,673,604

GIT1

GIT ArfGAP 1

involved_in

GO_REF:0000107

NCBI chr12:45,768,172...45,783,652
Ensembl chr12:45,768,174...45,783,747

HSP70.2

heat shock protein 70.2

involved_in

ISS

GO_REF:0000024

NCBI chr 7:23,925,929...23,927,854

LOC100624559

myomegalin

involved_in

(PMID:29162697)

PMID:29162697

NCBI chr 4:100,646,939...100,863,353
Ensembl chr 4:100,646,938...100,863,250

MECP2

methyl-CpG binding protein 2

involved_in

GO_REF:0000107

NCBI chr X:124,735,523...124,789,063
Ensembl chr X:124,735,656...124,789,110

p21 (RAC1) activated kinase 1

involved_in

GO_REF:0000107

NCBI chr 9:11,830,095...11,973,074
Ensembl chr 9:11,830,093...12,113,670

positive regulation of microtubule polymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKAP9

A-kinase anchoring protein 9

involved_in

GO_REF:0000107

NCBI chr 9:71,895,615...72,054,898
Ensembl chr 9:71,895,630...72,054,897

ANKRD53

ankyrin repeat domain 53

involved_in

(PMID:21873635)

NCBI chr 3:71,549,611...71,557,062
Ensembl chr 3:71,546,681...71,554,537

APC

APC regulator of WNT signaling pathway

acts_upstream_of_or_within

(MGI:3656452|PMID:16525027)

PMID:16525027

MGI:3656452

NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,912

ARL2

ADP ribosylation factor like GTPase 2

involved_in

InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr 2:7,157,963...7,167,024
Ensembl chr 2:7,157,963...7,167,329

ARL3

ADP ribosylation factor like GTPase 3

involved_in

InterPro

GO_REF:0000002

NCBI chr14:113,668,375...113,699,583
Ensembl chr14:113,665,270...113,707,501

caveolin 1

NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465

caveolin 3

NCBI chr13:65,117,868...65,130,886
Ensembl chr13:65,117,776...65,134,066

CDK5RAP2

CDK5 regulatory subunit associated protein 2

involved_in

Ensembl
GO_Central
GO_Central

(PMID:21873635)

GO_REF:0000107

NCBI chr 1:260,465,809...260,648,070
Ensembl chr 1:260,467,159...260,635,443

CDKN1B

cyclin dependent kinase inhibitor 1B

involved_in
acts_upstream_of_or_within

(MGI:3529385|PMID:15652749)

PMID:15652749

GO_REF:0000107 MGI:3529385

NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831

CLIP1

CAP-Gly domain containing linker protein 1

involved_in

(PMID:21873635)

NCBI chr14:30,320,870...30,467,095
Ensembl chr14:30,320,958...30,467,686

DCTN1

dynactin subunit 1

involved_in

GO_REF:0000107

NCBI chr 3:68,642,562...68,673,605
Ensembl chr 3:68,643,247...68,673,604

DRG1

developmentally regulated GTP binding protein 1

involved_in

GO_REF:0000107

NCBI chr14:48,126,807...48,153,103
Ensembl chr14:48,126,863...48,157,941

FES

FES proto-oncogene, tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 7:53,472,947...53,485,084
Ensembl chr 7:53,472,946...53,485,082

GDA

guanine deaminase

involved_in

PMID:14730308

NCBI chr 1:225,425,389...225,589,835
Ensembl chr 1:225,402,117...225,589,830

MAP1B

microtubule associated protein 1B

NCBI chr16:48,403,338...48,501,453
Ensembl chr16:48,403,526...48,498,896

MAPK8

mitogen-activated protein kinase 8

NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,172,200

MAPRE1

microtubule associated protein RP/EB family member 1

involved_in

GO_REF:0000107

NCBI chr17:36,390,698...36,426,435
Ensembl chr17:36,387,062...36,487,494

MAPT

microtubule associated protein tau

involved_in

(PMID:1421571), (PMID:7706316)

PMID:1421571 PMID:7706316

NCBI chr12:17,098,259...17,211,483
Ensembl chr12:17,095,587...17,211,368

MET

MET proto-oncogene, receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,044...29,541,512

NAV3

neuron navigator 3

involved_in

GO_REF:0000107

NCBI chr 5:103,013,798...103,863,222
Ensembl chr 5:103,013,798...103,368,021

NIN

ninein

involved_in

GO_REF:0000107

NCBI chr 1:180,477,269...180,621,980
Ensembl chr 1:180,479,588...180,621,895

NUMA1

nuclear mitotic apparatus protein 1

involved_in

GO_REF:0000107

NCBI chr 9:6,591,943...6,662,966
Ensembl chr 9:6,591,943...6,662,842

OCLN

occludin

involved_in

(PMID:20152177)

PMID:20152177

NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,498...47,654,033

p21 (RAC1) activated kinase 1

involved_in

GO_REF:0000107

NCBI chr 9:11,830,095...11,973,074
Ensembl chr 9:11,830,093...12,113,670

PSRC1

proline and serine rich coiled-coil 1

involved_in

GO_REF:0000107

NCBI chr 4:110,813,306...110,819,815
Ensembl chr 4:110,813,339...110,821,216

Rac family small GTPase 1

involved_in

GO_REF:0000107

NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,771...4,803,687

RPS3

ribosomal protein S3

involved_in

GO_REF:0000107

NCBI chr 9:9,612,939...9,630,404
Ensembl chr 9:9,616,456...9,630,413

SLAIN1

SLAIN motif family member 1

involved_in

(PMID:21873635)

NCBI chr11:49,807,976...49,886,829
Ensembl chr11:49,807,994...49,886,820

SLAIN2

SLAIN motif family member 2

involved_in

Ensembl
Ensembl
GO_Central
GO_Central

(PMID:21873635)

GO_REF:0000107

NCBI chr 8:38,241,497...38,320,663
Ensembl chr 8:38,241,598...38,322,031

TOGARAM1

TOG array regulator of axonemal microtubules 1

involved_in

(MGI:5796072|PMID:26378256)

PMID:26378256

MGI:5796072

NCBI chr 1:175,198,172...175,274,309
Ensembl chr 1:175,198,385...175,275,184

positive regulation of sarcomere organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP10

bone morphogenetic protein 10

involved_in

GO_REF:0000107

NCBI chr 3:73,519,904...73,530,448
Ensembl chr 3:73,519,934...73,529,977

EDN1

endothelin 1

involved_in

GO_REF:0000107

NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348

EP300

E1A binding protein p300

NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760

MYLK3

myosin light chain kinase 3

involved_in

PMID:17885681

NCBI chr 6:37,850,117...37,920,862
Ensembl chr 6:37,850,754...37,920,768

PROX1

prospero homeobox 1

involved_in

GO_REF:0000107

NCBI chr 9:129,527,704...129,583,693
Ensembl chr 9:129,532,164...129,580,979

positive regulation of spindle assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DYNC1H1

dynein cytoplasmic 1 heavy chain 1

involved_in

GO_REF:0000107

GPSM2

G protein signaling modulator 2

involved_in

GO_REF:0000107

NCBI chr 4:111,100,912...111,165,902
Ensembl chr 4:111,102,396...111,165,886

MAPK15

mitogen-activated protein kinase 15

involved_in

GO_REF:0000107

NCBI chr 4:909,266...915,537
Ensembl chr 4:902,439...915,475

NUMA1

nuclear mitotic apparatus protein 1

involved_in

GO_REF:0000107

NCBI chr 9:6,591,943...6,662,966
Ensembl chr 9:6,591,943...6,662,842

SPAG5

sperm associated antigen 5

involved_in

GO_REF:0000107

NCBI chr12:44,827,947...44,848,527
Ensembl chr12:44,827,786...44,848,529

positive regulation of stress fiber assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,711

APOA1

apolipoprotein A1

involved_in

GO_REF:0000107

NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978

ARHGEF10

Rho guanine nucleotide exchange factor 10

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr15:33,370,093...33,465,852

ARHGEF10L

Rho guanine nucleotide exchange factor 10 like

involved_in

GO_Central
Ensembl
GO_Central
Ensembl

(PMID:21873635)

GO_REF:0000107

NCBI chr 6:76,064,212...76,229,310
Ensembl chr 6:76,064,311...76,229,306

ARHGEF15

Rho guanine nucleotide exchange factor 15

involved_in

PMID:12775584

NCBI chr12:53,495,409...53,506,373
Ensembl chr12:53,495,453...53,506,352

ARHGEF5

Rho guanine nucleotide exchange factor 5

involved_in

GO_REF:0000107

NCBI chr 9:113,364,849...113,394,446
Ensembl chr 9:113,364,879...113,394,389

BAG4

BAG cochaperone 4

involved_in

GO_REF:0000107

NCBI chr15:48,299,456...48,348,810
Ensembl chr15:48,299,662...48,348,527

BRAF

B-Raf proto-oncogene, serine/threonine kinase

involved_in
acts_upstream_of_or_within

(MGI:3047520|PMID:15199148)

PMID:15199148

GO_REF:0000107 MGI:3047520

NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,959...9,132,553

capping protein regulator and myosin 1 linker 1

involved_in

GO_REF:0000107

NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,739...20,353,431

CCDC88A

coiled-coil domain containing 88A

involved_in

GO_REF:0000107

NCBI chr 3:85,811,043...85,971,162
Ensembl chr 3:85,811,106...85,941,868

CCN2

cellular communication network factor 2

involved_in

GO_REF:0000107

NCBI chr 1:31,674,398...31,677,697
Ensembl chr 1:31,673,798...31,677,696

CD47

CD47 molecule

involved_in

PMID:12023387

NCBI chr13:151,427,933...151,488,064
Ensembl chr13:151,429,288...151,502,164

CDC42

cell division cycle 42

involved_in

GO_REF:0000107

NCBI chr 6:80,035,034...80,089,243
Ensembl chr 6:80,035,122...80,089,233

EPHA1

EPH receptor A1

involved_in

UniProt
Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr18:6,843,305...6,860,976
Ensembl chr18:6,843,299...6,860,991

EVL

Enah/Vasp-like

involved_in

GO_REF:0000107

NCBI chr 7:120,911,814...121,056,556
Ensembl chr 7:120,911,220...121,056,558

FERMT2

FERM domain containing kindlin 2

involved_in

GO_REF:0000107

NCBI chr 1:182,519,681...182,606,890
Ensembl chr 1:182,519,681...182,606,869

FHOD1

formin homology 2 domain containing 1

involved_in

GO_REF:0000107

NCBI chr 6:27,867,499...27,883,077
Ensembl chr 6:27,867,502...27,883,072

GPR65

G protein-coupled receptor 65

involved_in

GO_REF:0000107

NCBI chr 7:109,978,913...109,997,688

ITGB1BP1

integrin subunit beta 1 binding protein 1

involved_in

GO_REF:0000107

NCBI chr 3:126,905,779...126,921,961
Ensembl chr 3:126,905,809...126,923,981

KISS1 receptor

NCBI chr 2:77,472,361...77,479,204
Ensembl chr 2:77,472,362...77,479,204

LIMCH1

LIM and calponin homology domains 1

involved_in

(PMID:21873635)

NCBI chr 8:32,433,035...32,792,553
Ensembl chr 8:32,433,030...32,792,546

LIMK1

LIM domain kinase 1

involved_in
acts_upstream_of_or_within

GO_Central
GO_Central
Ensembl
MGI
Ensembl

(PMID:21873635)
(MGI:3047520|PMID:15199148)

PMID:15199148 PMID:21873635

GO_REF:0000107 MGI:3047520

NCBI chr 3:11,252,820...11,279,286
Ensembl chr 3:11,252,645...11,279,285

LPAR1

lysophosphatidic acid receptor 1

involved_in

GO_REF:0000107

NCBI chr 1:251,811,583...251,979,828
Ensembl chr 1:251,811,584...251,979,159

MTOR

mechanistic target of rapamycin kinase

involved_in
acts_upstream_of_or_within

(MGI:3510095|PMID:15467718)

GO_REF:0000107 MGI:3510095

NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888

MYOC

myocilin

involved_in

GO_REF:0000107

NCBI chr 9:114,087,370...114,098,765
Ensembl chr 9:114,087,374...114,098,743

NF2

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

involved_in

GO_REF:0000107

NCBI chr14:46,653,869...46,726,421
Ensembl chr14:46,653,902...46,731,999

NADPH oxidase 4

NCBI chr 9:22,622,105...22,776,691
Ensembl chr 9:22,624,195...22,776,554

NRP1

neuropilin 1

involved_in

GO_REF:0000107

NCBI chr10:56,280,673...56,430,832
Ensembl chr10:56,280,363...56,430,777

p21 (RAC1) activated kinase 1

involved_in

UniProt
Ensembl
UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr 9:11,830,095...11,973,074
Ensembl chr 9:11,830,093...12,113,670

PDLIM4

PDZ and LIM domain 4

involved_in

PMID:14729062
PMID:22659164

PMID:14729062 PMID:22659164

RGD:1300470 RGD:13432282

NCBI chr 2:134,555,367...134,570,356
Ensembl chr 2:134,555,666...134,570,350

profilin 1

NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,696...51,973,660

profilin 2

involved_in

(MGI:5545940|PMID:23153535)
(PMID:23153535)

MGI:5545940

NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742

PPM1E

protein phosphatase, Mg2+/Mn2+ dependent 1E

involved_in

GO_REF:0000107

NCBI chr12:35,051,936...35,262,698
Ensembl chr12:35,051,951...35,262,703

PPM1F

protein phosphatase, Mg2+/Mn2+ dependent 1F

involved_in

GO_REF:0000107

NCBI chr14:50,040,612...50,083,047
Ensembl chr14:50,040,663...50,063,326

PRKCQ

protein kinase C theta

NCBI chr10:64,442,588...64,596,528
Ensembl chr10:64,443,251...64,600,339

PXN

paxillin

involved_in

(PMID:24863063)

PMID:24863063

NCBI chr14:40,227,894...40,278,785
Ensembl chr14:40,227,894...40,278,766

Rac family small GTPase 1

involved_in

GO_REF:0000107

NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,771...4,803,687

RAPGEF3

Rap guanine nucleotide exchange factor 3

involved_in

GO_REF:0000107

NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,289...78,134,103

RGCC

regulator of cell cycle

involved_in

PMID:15467718 PMID:25071083

GO_REF:0000107

NCBI chr11:25,481,845...25,496,548
Ensembl chr11:25,478,877...25,496,519

RHOA

ras homolog family member A

involved_in
acts_upstream_of_or_within

ISS
IEA
ISO

(PMID:15467718)
(MGI:6316493|PMID:25071083)

AgBase
AgBase
Ensembl
MGI

GO_REF:0000024 GO_REF:0000107 MGI:6316493

NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,836...32,003,722

RHOC

ras homolog family member C

involved_in

GO_REF:0000107

NCBI chr 4:107,731,713...107,737,705
Ensembl chr 4:107,731,536...107,737,701

ROCK2

Rho associated coiled-coil containing protein kinase 2

involved_in

GO_REF:0000107

NCBI chr 3:125,353,063...125,493,368
Ensembl chr 3:125,353,119...125,491,963

S100A10

S100 calcium binding protein A10

involved_in

GO_REF:0000107

NCBI chr 4:97,261,752...97,272,517
Ensembl chr 4:97,261,815...97,272,513

syndecan 4

NCBI chr17:47,650,387...47,670,499

SERPINF2

serpin family F member 2

involved_in

GO_REF:0000107

NCBI chr12:47,934,551...47,942,283
Ensembl chr12:47,933,864...47,942,287

SH3PXD2B

SH3 and PX domains 2B

involved_in

(MGI:5800302|PMID:27711054)

PMID:27711054

MGI:5800302

NCBI chr16:51,733,170...51,858,774
Ensembl chr16:51,733,131...51,858,772

SMAD3

SMAD family member 3

during transdifferentiation

RGD

PMID:15987742

RGD:2300418

NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,083...165,124,454

SORBS3

sorbin and SH3 domain containing 3

involved_in

GO_REF:0000107

NCBI chr14:6,802,944...6,831,152
Ensembl chr14:6,808,166...6,828,975

SYNPO2L

synaptopodin 2 like

involved_in

(MGI:6102963|PMID:29206857)

PMID:29206857

MGI:6102963

NCBI chr14:76,456,170...76,466,661
Ensembl chr14:76,456,167...76,473,423

TAC1

tachykinin precursor 1

NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,535...77,206,526

TACR1

tachykinin receptor 1

NCBI chr 3:67,839,367...68,021,733
Ensembl chr 3:67,839,411...68,021,728

TESK1

testis associated actin remodelling kinase 1

involved_in

(PMID:21873635)

NCBI chr 1:236,341,160...236,345,964
Ensembl chr 1:236,341,179...236,345,962

TGFB3

transforming growth factor beta 3

involved_in

GO_REF:0000107

NCBI chr 7:99,133,873...99,162,239
Ensembl chr 7:99,133,511...99,162,232

TGFBR1

transforming growth factor beta receptor 1

involved_in

GO_REF:0000107

NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,859,270...240,918,528

TPM1

tropomyosin 1

involved_in

PMID:15897890

NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,981...109,019,440

TSC1

TSC complex subunit 1

NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,952

WNT11

Wnt family member 11

involved_in

GO_REF:0000107

NCBI chr 9:10,413,182...10,435,158
Ensembl chr 9:10,413,187...10,435,100

WNT4

Wnt family member 4

involved_in

(MGI:5487484|PMID:23027131)

PMID:23027131

MGI:5487484

NCBI chr 6:80,110,238...80,138,165

regulation of actin cytoskeleton organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

acts_upstream_of_or_within
involved_in

(MGI:1327082|PMID:9883720)
(MGI:4840122|PMID:20980600)

PMID:9883720 PMID:20980600

GO_REF:0000107 MGI:1327082 MGI:4840122

NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,711

ARHGAP18

Rho GTPase activating protein 18

involved_in

GO_REF:0000107

NCBI chr 1:33,527,734...33,717,980
Ensembl chr 1:33,527,734...33,717,977

ARHGAP35

Rho GTPase activating protein 35

involved_in

GO_REF:0000107

NCBI chr 6:52,711,463...52,841,295
Ensembl chr 6:52,711,901...52,841,288

ARHGAP44

Rho GTPase activating protein 44

involved_in

GO_Central
Ensembl
GO_Central
Ensembl

(PMID:21873635)

GO_REF:0000107

NCBI chr12:57,049,900...57,206,706
Ensembl chr12:57,049,895...57,206,889

ARHGEF19

Rho guanine nucleotide exchange factor 19

involved_in
acts_upstream_of_or_within

GO_Central
Ensembl
GO_Central
MGI

(PMID:21873635)
(PMID:20643356)

PMID:20643356 PMID:21873635

GO_REF:0000107

NCBI chr 6:75,317,811...75,335,292
Ensembl chr 6:75,317,823...75,335,270

ARHGEF5

Rho guanine nucleotide exchange factor 5

involved_in

GO_REF:0000107

NCBI chr 9:113,364,849...113,394,446
Ensembl chr 9:113,364,879...113,394,389

BAIAP2

BAR/IMD domain containing adaptor protein 2

involved_in

InterPro
Ensembl
InterPro

GO_REF:0000002 GO_REF:0000107

NCBI chr12:1,609,420...1,666,965
Ensembl chr12:1,603,538...1,670,076

BST1

bone marrow stromal cell antigen 1

involved_in

GO_REF:0000107

NCBI chr 8:11,011,131...11,043,622
Ensembl chr 8:11,011,241...11,042,825

BST2

bone marrow stromal cell antigen 2

involved_in

PMID:19273615

NCBI chr 2:60,305,306...60,308,295
Ensembl chr 2:60,305,252...60,309,936

CCDC88A

coiled-coil domain containing 88A

involved_in

InterPro
InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr 3:85,811,043...85,971,162
Ensembl chr 3:85,811,106...85,941,868

CDK10

cyclin dependent kinase 10

involved_in

GO_REF:0000107

NCBI chr 6:332,239...339,130
Ensembl chr 6:332,242...339,142

CDK5R1

cyclin dependent kinase 5 regulatory subunit 1

involved_in

GO_REF:0000107

NCBI chr12:42,456,063...42,494,494
Ensembl chr12:42,493,321...42,494,659

CLASP2

cytoplasmic linker associated protein 2

involved_in

(PMID:24520051)

PMID:24520051

NCBI chr13:19,305,430...19,510,589
Ensembl chr13:19,305,180...19,510,585

coronin 1A

involved_in

GO_REF:0000107

NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,899...18,342,380

CORO2B

coronin 2B

acts_upstream_of_or_within
involved_in

(PMID:29162887)

PMID:29162887

GO_REF:0000107

NCBI chr 1:166,465,870...166,608,840
Ensembl chr 1:166,465,953...166,608,367

CRK

CRK proto-oncogene, adaptor protein

involved_in
acts_upstream_of_or_within

PMID:11870224 PMID:20980600

(PMID:11870224)
(MGI:4840122|PMID:20980600)

UniProt
MGI

MGI:4840122

NCBI chr12:47,656,805...47,685,641

DIXDC1

DIX domain containing 1

involved_in

(MGI:4821185|PMID:20624590)

DFLAT

PMID:20624590

MGI:4821185

NCBI chr 9:39,666,454...39,734,909

DLC1

DLC1 Rho GTPase activating protein

involved_in

GO_REF:0000107

NCBI chr17:1,169,709...1,637,171
Ensembl chr17:1,170,195...1,637,162

DMTN

dematin actin binding protein

involved_in

GO_REF:0000107

NCBI chr14:6,315,643...6,346,722
Ensembl chr14:6,321,870...6,346,870

EFNA5

ephrin A5

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 2:112,533,124...112,821,293
Ensembl chr 2:112,534,917...112,815,628

EPHA3

EPH receptor A3

involved_in

GO_REF:0000107

NCBI chr13:166,592,492...166,942,791
Ensembl chr13:166,591,686...166,942,767

EPHA5

EPH receptor A5

involved_in

(MGI:5294297|PMID:17448994)

PMID:17448994

MGI:5294297

NCBI chr 8:63,285,006...63,604,734
Ensembl chr 8:63,285,489...63,604,734

EZR

ezrin

NOT|involved_in

(PMID:20551903)

PMID:20551903

NCBI chr 1:8,403,362...8,452,750
Ensembl chr 1:8,403,453...8,452,750

F11 receptor

involved_in

GO_REF:0000107

NCBI chr 4:89,425,101...89,447,889
Ensembl chr 4:89,425,039...89,449,932

FAM107A

family with sequence similarity 107 member A

involved_in

(PMID:21873635)

NCBI chr13:40,276,896...40,369,708

FAM3D

FAM3 metabolism regulating signaling molecule D

involved_in

(PMID:21873635)

NCBI chr13:40,375,536...40,456,057

FSCN1

fascin actin-bundling protein 1

involved_in

GO_REF:0000107

NCBI chr 3:4,134,173...4,143,275
Ensembl chr 3:4,134,170...4,145,394

FZD10

frizzled class receptor 10

involved_in

GO_REF:0000107

NCBI chr14:24,919,483...24,922,554
Ensembl chr14:24,920,679...24,922,424

GPM6B

glycoprotein M6B

involved_in

GO_REF:0000107

NCBI chr X:10,429,496...10,582,768
Ensembl chr X:10,430,281...10,643,429

GRHL3

grainyhead like transcription factor 3

acts_upstream_of_or_within
involved_in

(PMID:20643356)

PMID:20643356

GO_REF:0000107

NCBI chr 6:82,014,022...82,050,240
Ensembl chr 6:82,014,046...82,050,236

HIP1R

huntingtin interacting protein 1 related

involved_in

GO_REF:0000107

NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216

HRG

histidine rich glycoprotein

involved_in

GO_REF:0000107

NCBI chr13:124,505,305...124,516,387
Ensembl chr13:124,505,303...124,516,384

interleukin 1 alpha

NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119

ILK

integrin linked kinase

positive regulation of alpha smooth muscle actin organization in aging cells

RGD

PMID:17234816

RGD:2301768

NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,647...3,159,858

IQGAP2

IQ motif containing GTPase activating protein 2

involved_in

(PMID:21873635)

NCBI chr 2:85,294,423...85,633,645
Ensembl chr 2:85,294,434...85,636,317

IQGAP3

IQ motif containing GTPase activating protein 3

involved_in

(PMID:21873635)

NCBI chr 4:93,495,999...93,556,915
Ensembl chr 4:93,513,079...93,559,020

ITGB3

integrin subunit beta 3

involved_in

GO_REF:0000107

NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,505...16,752,292

LOC102159820

cadherin EGF LAG seven-pass G-type receptor 1

involved_in
acts_upstream_of_or_within

(MGI:4452277|PMID:20223754)

PMID:20223754

GO_REF:0000107 MGI:4452277

NCBI chr 5:3,114,410...3,203,378
Ensembl chr 5:2,980,069...3,204,803

LRP1

LDL receptor related protein 1

involved_in

(MGI:4365879|PMID:19742316)

PMID:19742316

MGI:4365879

NCBI chr 5:22,435,636...22,519,276

MLST8

MTOR associated protein, LST8 homolog

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 3:39,778,746...39,786,206
Ensembl chr 3:39,778,754...39,788,309

MTOR

mechanistic target of rapamycin kinase

involved_in

GO_REF:0000107

NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888

MYO1F

myosin IF

acts_upstream_of_or_within

(MGI:3664353|PMID:17023661)

PMID:17023661

MGI:3664353

NCBI chr 2:70,753,143...70,792,938
Ensembl chr 2:70,753,138...70,792,938

NEDD9

neural precursor cell expressed, developmentally down-regulated 9

involved_in

GO_REF:0000107

NCBI chr 7:7,807,042...8,093,553
Ensembl chr 7:7,807,044...8,093,553

ODAM

odontogenic, ameloblast associated

involved_in

GO_REF:0000107

NCBI chr 8:67,059,284...67,068,117
Ensembl chr 8:67,058,472...67,069,291

p21 (RAC1) activated kinase 1

involved_in

RGD
GO_Central
GO_Central

(PMID:21873635)

PMID:18347024 PMID:21873635

RGD:2299169

NCBI chr 9:11,830,095...11,973,074
Ensembl chr 9:11,830,093...12,113,670

PAK3

p21 (RAC1) activated kinase 3

NCBI chr X:90,941,976...91,244,331
Ensembl chr X:90,942,232...91,239,440

PAM

peptidylglycine alpha-amidating monooxygenase

NCBI chr 2:108,255,923...108,536,192
Ensembl chr 2:108,255,930...108,536,881

PDGFRB

platelet derived growth factor receptor beta

involved_in

(MGI:4365879|PMID:19742316)

PMID:19742316

MGI:4365879

NCBI chr 2:151,155,753...151,192,818
Ensembl chr 2:151,155,754...151,192,647

PEAK3

PEAK family member 3

involved_in

GO_REF:0000107

NCBI chr 2:76,285,163...76,291,295
Ensembl chr 2:76,285,882...76,291,291

PRKCD

protein kinase C delta

involved_in

GO_REF:0000107

NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,264...35,323,356

Rac family small GTPase 1

involved_in

(PMID:21873635)

NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,771...4,803,687

RAC2

Rac family small GTPase 2

involved_in

(PMID:21873635)

NCBI chr 5:10,553,986...10,571,082
Ensembl chr 5:10,553,433...10,573,017

RAC3

Rac family small GTPase 3

involved_in

(PMID:21873635)

AgBase
AgBase
Ensembl
GO_Central
GO_Central

NCBI chr12:981,072...984,222
Ensembl chr12:981,076...984,227

RHOA

ras homolog family member A

involved_in

ISS
IEA
IBA

(PMID:21873635)

GO_REF:0000024 GO_REF:0000107

NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,836...32,003,722

RHOBTB1

Rho related BTB domain containing 1

involved_in

(PMID:21873635)

NCBI chr14:64,326,461...64,465,331
Ensembl chr14:64,326,453...64,465,281

RHOBTB3

Rho related BTB domain containing 3

involved_in

(PMID:21873635)

NCBI chr 2:102,334,747...102,395,134
Ensembl chr 2:102,334,741...102,495,758

RHOC

ras homolog family member C

involved_in

(PMID:21873635)

NCBI chr 4:107,731,713...107,737,705
Ensembl chr 4:107,731,536...107,737,701

RHOD

ras homolog family member D

involved_in

(PMID:21873635)

NCBI chr 2:5,392,546...5,404,214
Ensembl chr 2:5,392,546...5,404,201

RHOF

ras homolog family member F, filopodia associated

involved_in

(PMID:21873635)

NCBI chr14:30,886,053...30,908,048
Ensembl chr14:30,889,790...30,908,419

RHOG

ras homolog family member G

involved_in

(PMID:21873635)

NCBI chr 9:6,283,558...6,295,376

RHOH

ras homolog family member H

involved_in

(PMID:21873635)

NCBI chr 8:31,321,005...31,372,366
Ensembl chr 8:31,321,113...31,372,364

RICTOR

RPTOR independent companion of MTOR complex 2

involved_in

GO_REF:0000107

NCBI chr16:24,109,934...24,250,019
Ensembl chr16:24,109,934...24,311,231

RND1

Rho family GTPase 1

involved_in

(PMID:21873635)

NCBI chr 5:14,914,652...14,922,032
Ensembl chr 5:14,914,642...14,937,020

RND2

Rho family GTPase 2

involved_in

(PMID:21873635)

NCBI chr12:19,866,597...19,870,205
Ensembl chr12:19,866,603...19,870,211

RND3

Rho family GTPase 3

involved_in

(PMID:21873635)

NCBI chr15:1,715,589...1,732,605
Ensembl chr15:1,715,207...1,734,419

ROCK1

Rho associated coiled-coil containing protein kinase 1

involved_in

GO_REF:0000107

NCBI chr 6:106,163,899...106,314,998
Ensembl chr 6:106,163,903...106,314,944

ROCK2

Rho associated coiled-coil containing protein kinase 2

involved_in

GO_REF:0000002

NCBI chr 3:125,353,063...125,493,368
Ensembl chr 3:125,353,119...125,491,963

SH3BP1

SH3 domain binding protein 1

involved_in

(PMID:21873635)

Ensembl
Ensembl
GO_Central
MGI
GO_Central

NCBI chr 5:10,172,303...10,187,883

SIGLEC15

sialic acid binding Ig like lectin 15

involved_in
acts_upstream_of_or_within

IEA
IBA
ISO

(PMID:21873635)
(MGI:5467208|PMID:22451653)

PMID:21873635 PMID:22451653

GO_REF:0000107 MGI:5467208

NCBI chr 1:95,475,108...95,492,675
Ensembl chr 1:95,475,447...95,492,709

SMIM22

small integral membrane protein 22

involved_in

GO_REF:0000107

NCBI chr 3:37,599,574...37,601,316

STAU2

staufen double-stranded RNA binding protein 2

NCBI chr 4:62,139,456...62,455,509
Ensembl chr 4:62,139,505...62,455,501

TAOK1

TAO kinase 1

involved_in

PMID:18216281

NCBI chr12:45,597,067...45,750,117
Ensembl chr12:45,597,057...45,744,356

TAOK2

TAO kinase 2

involved_in

GO_REF:0000107

NCBI chr 3:18,178,347...18,198,092
Ensembl chr 3:18,166,847...18,198,089

TESK1

testis associated actin remodelling kinase 1

involved_in

GO_REF:0000107

NCBI chr 1:236,341,160...236,345,964
Ensembl chr 1:236,341,179...236,345,962

TGFB2

transforming growth factor beta 2

involved_in

(MGI:5688835|PMID:21984612)

PMID:21984612

MGI:5688835

NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,424...8,405,771

twinfilin actin binding protein 1

involved_in

GO_REF:0000117

NCBI chr 5:74,868,586...74,881,220
Ensembl chr 5:74,868,585...74,893,713

TWF2

twinfilin actin binding protein 2

involved_in

Ensembl
UniProt

GO_REF:0000107 GO_REF:0000117

NCBI chr13:34,361,294...34,370,997
Ensembl chr13:34,361,292...34,371,842

VANGL2

VANGL planar cell polarity protein 2

acts_upstream_of_or_within

(MGI:4452277|PMID:20223754)

PMID:20223754

MGI:4452277

NCBI chr 4:90,051,994...90,080,701
Ensembl chr 4:90,053,380...90,080,656

YWHAE

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

involved_in

GO_REF:0000107

NCBI chr12:47,601,133...47,645,327
Ensembl chr12:47,600,502...47,690,398

regulation of actin cytoskeleton organization by cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

JAM3

junctional adhesion molecule 3

involved_in
acts_upstream_of_or_within

(MGI:3054279|PMID:15372036)

PMID:15372036

GO_REF:0000107 MGI:3054279

NCBI chr 9:60,629,245...60,738,979
Ensembl chr 9:60,613,400...60,738,924

regulation of actin cytoskeleton reorganization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABI3BP

ABI family member 3 binding protein

involved_in

PMID:22485184

NCBI chr13:158,013,704...158,291,093
Ensembl chr13:158,013,718...158,291,103

ARHGDIA

Rho GDP dissociation inhibitor alpha

involved_in

GO_REF:0000107

NCBI chr12:1,113,358...1,117,319
Ensembl chr12:1,113,355...1,121,311

ARHGDIB

Rho GDP dissociation inhibitor beta

involved_in

GO_REF:0000107

NCBI chr 5:57,576,754...57,598,395
Ensembl chr 5:57,576,811...57,598,386

capping protein regulator and myosin 1 linker 1

involved_in

(PMID:21873635)

NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,739...20,353,431

CARMIL2

capping protein regulator and myosin 1 linker 2

involved_in

(PMID:21873635)

NCBI chr 6:28,265,130...28,277,649
Ensembl chr 6:28,264,320...28,279,703

CARMIL3

capping protein regulator and myosin 1 linker 3

involved_in

(PMID:21873635)

NCBI chr 7:75,222,528...75,241,243
Ensembl chr 7:75,222,528...75,241,243

CD2AP

CD2 associated protein

involved_in
acts_upstream_of_or_within

(MGI:5297732|PMID:21911934)

PMID:21911934

GO_REF:0000107 MGI:5297732

NCBI chr 7:42,218,016...42,332,523
Ensembl chr 7:42,217,588...42,332,518

CSF1R

colony stimulating factor 1 receptor

involved_in

GO_REF:0000107

NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,138...151,147,634

CTSL

cathepsin L

acts_upstream_of_or_within

(MGI:5297732|PMID:21911934)

PMID:21911934

MGI:5297732

NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618

DAPK3

death associated protein kinase 3

involved_in

GO_REF:0000107

NCBI chr 2:74,758,962...74,776,355
Ensembl chr 2:74,759,022...74,779,954

ESAM

endothelial cell adhesion molecule

involved_in

GO_REF:0000107

NCBI chr 9:51,983,019...51,992,415
Ensembl chr 9:51,983,019...51,992,393

F11 receptor

involved_in

GO_REF:0000107

NCBI chr 4:89,425,101...89,447,889
Ensembl chr 4:89,425,039...89,449,932

GMFG

glia maturation factor gamma

involved_in

GO_REF:0000002

NCBI chr 6:47,990,241...47,997,332
Ensembl chr 6:47,990,237...48,000,590

IQGAP2

IQ motif containing GTPase activating protein 2

involved_in

GO_REF:0000107

NCBI chr 2:85,294,423...85,633,645
Ensembl chr 2:85,294,434...85,636,317

MDK

midkine

involved_in

GO_REF:0000107

NCBI chr 2:16,130,787...16,133,791
Ensembl chr 2:16,130,782...16,133,510

NOTCH2

notch receptor 2

involved_in

GO_REF:0000107

NCBI chr 4:100,951,522...101,152,348
Ensembl chr 4:100,951,507...101,150,198

PTK2B

protein tyrosine kinase 2 beta

involved_in

Ensembl
InterPro
Ensembl
InterPro

GO_REF:0000002 GO_REF:0000107

NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,194

RAPGEF3

Rap guanine nucleotide exchange factor 3

involved_in

GO_REF:0000107

NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,289...78,134,103

RHOD

ras homolog family member D

involved_in

(MGI:5512821|PMID:23454120)

PMID:23454120

MGI:5512821

NCBI chr 2:5,392,546...5,404,214
Ensembl chr 2:5,392,546...5,404,201

SEMA3E

semaphorin 3E

involved_in

GO_REF:0000107

NCBI chr 9:96,682,178...96,941,074
Ensembl chr 9:96,682,246...96,941,074

TGFB1

transforming growth factor beta 1

involved_in
acts_upstream_of_or_within

(MGI:5297732|PMID:21911934)

PMID:21911934

GO_REF:0000107 MGI:5297732

NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048

TRPM2

transient receptor potential cation channel subfamily M member 2

involved_in

GO_REF:0000107

NCBI chr13:207,212,339...207,263,313
Ensembl chr13:207,211,952...207,264,982

regulation of actin filament bundle assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FLNA

filamin A

involved_in

(MGI:4838360|PMID:20713593)

PMID:20713593

MGI:4838360

NCBI chr X:124,889,934...124,915,000
Ensembl chr X:124,890,142...124,917,171

RDX

radixin

involved_in

GO_REF:0000107

NCBI chr 9:38,243,608...38,299,561
Ensembl chr 9:38,220,441...38,376,439

regulation of actin filament depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SH3BP1

SH3 domain binding protein 1

involved_in

(PMID:24841563)

PMID:24841563

NCBI chr 5:10,172,303...10,187,883

WDR1

WD repeat domain 1

involved_in

GO_REF:0000107

NCBI chr 8:6,413,338...6,452,383
Ensembl chr 8:6,413,347...6,452,346

regulation of actin filament length

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EPS8

epidermal growth factor receptor pathway substrate 8

involved_in

GO_REF:0000107

NCBI chr 5:56,817,445...57,005,117
Ensembl chr 5:56,817,606...57,005,114

MYO3A

myosin IIIA

acts_upstream_of_or_within

(MGI:5766107|PMID:26754646)

PMID:26754646

MGI:5766107

NCBI chr10:49,392,119...49,623,575

MYO3B

myosin IIIB

acts_upstream_of_or_within

(MGI:5766107|PMID:26754646)

PMID:26754646

MGI:5766107

NCBI chr15:76,432,429...76,855,443
Ensembl chr15:76,401,963...76,855,432

regulation of actin filament organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C10H9orf72

chromosome 10 C9orf72 homolog

involved_in

GO_REF:0000107

NCBI chr10:38,389,366...38,415,903
Ensembl chr10:38,389,331...38,415,903

profilin 1

involved_in

GO_REF:0000117

NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,696...51,973,660

profilin 2

involved_in

GO_REF:0000117

NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,277,232

RGS4

regulator of G protein signaling 4

NCBI chr 4:87,383,336...87,390,478
Ensembl chr 4:87,381,386...87,390,467

regulation of actin filament polymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABITRAM

actin binding transcription modulator

involved_in

(PMID:21873635)

NCBI chr 1:249,898,994...249,905,397

ARHGAP18

Rho GTPase activating protein 18

involved_in

GO_Central
Ensembl
GO_Central
Ensembl

(PMID:21873635)

GO_REF:0000107

NCBI chr 1:33,527,734...33,717,980
Ensembl chr 1:33,527,734...33,717,977

ARHGAP28

Rho GTPase activating protein 28

involved_in

(PMID:21873635)

NCBI chr 6:100,494,385...100,681,008
Ensembl chr 6:100,493,261...100,655,708

ARPC1A

actin related protein 2/3 complex subunit 1A

involved_in

GO_REF:0000002

NCBI chr 3:6,296,257...6,324,526
Ensembl chr 3:6,197,760...6,324,524

ARPC1B

actin related protein 2/3 complex subunit 1B

involved_in

GO_REF:0000002

NCBI chr 3:6,329,737...6,342,641
Ensembl chr 3:6,220,939...6,342,637

actin related protein 2/3 complex subunit 2

involved_in

GO_REF:0000002

NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059

ARPC3

actin related protein 2/3 complex subunit 3

involved_in

GO_REF:0000002

NCBI chr14:31,814,382...31,823,452
Ensembl chr14:31,814,150...31,826,855

ARPC4

actin related protein 2/3 complex subunit 4

involved_in

GO_REF:0000002

NCBI chr13:66,075,926...66,093,986
Ensembl chr13:66,055,364...66,100,310

ARPC5

actin related protein 2/3 complex subunit 5

involved_in

GO_REF:0000002

NCBI chr 9:124,839,062...124,847,906
Ensembl chr 9:124,837,773...124,848,108

ARPC5L

actin related protein 2/3 complex subunit 5 like

involved_in

GO_REF:0000002

NCBI chr 1:265,645,800...265,653,513
Ensembl chr 1:265,642,375...265,654,015

BAIAP2L1

BAR/IMD domain containing adaptor protein 2 like 1

involved_in

GO_REF:0000002

NCBI chr 3:5,472,305...5,567,926
Ensembl chr 3:5,472,315...5,567,876

coronin 1A

acts_upstream_of_or_within
involved_in

(MGI:3818245|PMID:18836449)

PMID:18836449

GO_REF:0000107 MGI:3818245

NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,899...18,342,380

CTTN

cortactin

involved_in

(PMID:21873635)

NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,102...3,060,855

CYFIP2

cytoplasmic FMR1 interacting protein 2

involved_in

GO_REF:0000002

NCBI chr16:65,852,584...66,001,576
Ensembl chr16:65,852,588...66,001,559

CYRIA

CYFIP related Rac1 interactor A

involved_in

GO_REF:0000002

NCBI chr 3:120,968,016...121,069,372
Ensembl chr 3:120,968,060...121,069,242

CYRIB

CYFIP related Rac1 interactor B

involved_in

GO_REF:0000002

NCBI chr 4:10,476,137...10,643,395

DAAM2

dishevelled associated activator of morphogenesis 2

involved_in

GO_REF:0000107

NCBI chr 7:35,127,245...35,285,933
Ensembl chr 7:35,159,711...35,285,941

DBN1

drebrin 1

involved_in

RGD
GO_Central
GO_Central

(PMID:21873635)

PMID:19222710 PMID:21873635

RGD:10395284

NCBI chr 2:80,480,603...80,495,797
Ensembl chr 2:80,479,460...80,496,873

DBNL

drebrin like

involved_in

(PMID:21873635)

NCBI chr18:48,713,335...48,725,692
Ensembl chr18:48,713,340...48,725,697

ELN

elastin

involved_in
acts_upstream_of_or_within

(MGI:3027647|PMID:14614988)

PMID:14614988

GO_REF:0000107 MGI:3027647

NCBI chr 3:11,214,194...11,245,891
Ensembl chr 3:11,214,073...11,244,897

ESAM

endothelial cell adhesion molecule

involved_in

GO_REF:0000107

NCBI chr 9:51,983,019...51,992,415
Ensembl chr 9:51,983,019...51,992,393

FCHSD1

FCH and double SH3 domains 1

involved_in

(PMID:21873635)

NCBI chr 2:143,289,854...143,301,921
Ensembl chr 2:143,289,859...143,304,416

FCHSD2

FCH and double SH3 domains 2

involved_in

(PMID:21873635)

NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,521...7,619,926

GBA2

glucosylceramidase beta 2

involved_in

GO_REF:0000107

NCBI chr 1:236,456,238...236,467,887
Ensembl chr 1:236,455,240...236,468,210

HAX1

HCLS1 associated protein X-1

involved_in

(PMID:21873635)

GO_REF:0000107

NCBI chr 4:95,467,629...95,470,972
Ensembl chr 4:95,467,629...95,470,288

HCLS1

hematopoietic cell-specific Lyn substrate 1

involved_in

Ensembl
GO_Central
Ensembl
GO_Central

(PMID:21873635)

GO_REF:0000107

NCBI chr13:138,852,387...138,883,088
Ensembl chr13:138,855,142...138,906,351

LATS1

large tumor suppressor kinase 1

involved_in

GO_REF:0000107

NCBI chr 1:16,274,955...16,320,980
Ensembl chr 1:16,274,970...16,320,619

PAK3

p21 (RAC1) activated kinase 3

involved_in

GO_REF:0000107

NCBI chr X:90,941,976...91,244,331
Ensembl chr X:90,942,232...91,239,440

profilin 2

involved_in

GO_Central
GO_Central
InterPro
RGD
InterPro

(PMID:21873635)

PMID:11027290 PMID:21873635

GO_REF:0000002 RGD:727303

NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742

PIK3R2

phosphoinositide-3-kinase regulatory subunit 2

involved_in
acts_upstream_of_or_within

(MGI:5613738|PMID:25217619)

PMID:25217619

GO_REF:0000107 MGI:5613738

NCBI chr 2:59,637,363...59,652,075

PLEKHG2

pleckstrin homology and RhoGEF domain containing G2

involved_in

GO_REF:0000107

NCBI chr 6:48,069,532...48,080,001
Ensembl chr 6:48,069,564...48,079,672

PPP1R9A

protein phosphatase 1 regulatory subunit 9A

NCBI chr 9:74,635,285...74,944,050
Ensembl chr 9:74,635,280...74,940,362

PREX1

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

NCBI chr17:50,352,273...50,550,402
Ensembl chr17:50,353,145...50,550,404

RASA1

RAS p21 protein activator 1

involved_in

GO_REF:0000107

NCBI chr 2:94,879,615...94,992,725
Ensembl chr 2:94,878,911...94,993,479

WASHC1

WASH complex subunit 1

acts_upstream_of_or_within

(MGI:5806548|PMID:26965651)

PMID:26965651

MGI:5806548

NCBI chr 5:67,395,737...67,412,408
Ensembl chr 5:67,391,277...67,412,434

regulation of actin nucleation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

villin 1

involved_in

UniProt
Ensembl
UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580

WASHC5

WASH complex subunit 5

involved_in
acts_upstream_of_or_within

IBA
ISO
IEA

(PMID:21873635)
(MGI:5883184|PMID:27390154)

GO_Central
MGI
GO_Central
Ensembl

PMID:21873635 PMID:27390154

GO_REF:0000107 MGI:5883184

NCBI chr 4:14,598,133...14,667,535
Ensembl chr 4:14,598,148...14,668,327

regulation of actin phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

twinfilin actin binding protein 1

involved_in

GO_REF:0000107

NCBI chr 5:74,868,586...74,881,220
Ensembl chr 5:74,868,585...74,893,713

regulation of actin polymerization or depolymerization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARHGAP35

Rho GTPase activating protein 35

involved_in

GO_REF:0000107

NCBI chr 6:52,711,463...52,841,295
Ensembl chr 6:52,711,901...52,841,288

BRK1

BRICK1 subunit of SCAR/WAVE actin nucleating complex

involved_in

(PMID:21873635)

NCBI chr13:66,315,438...66,324,641
Ensembl chr13:66,315,433...66,324,174

CIT

citron rho-interacting serine/threonine kinase

NCBI chr14:33,009,828...33,195,985
Ensembl chr14:33,009,867...33,196,286

coronin 1A

acts_upstream_of_or_within
involved_in

(MGI:3654559|PMID:16902139)

PMID:16902139

GO_REF:0000107 MGI:3654559

NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,899...18,342,380

HYAL1

hyaluronidase 1

involved_in

GO_REF:0000107

NCBI chr13:32,798,135...32,800,705
Ensembl chr13:32,793,569...32,800,796

HYAL1

hyaluronidase 1

involved_in