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ONTOLOGY REPORT - ANNOTATIONS


Term:corticotropin secretion
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Accession:GO:0051458 term browser browse the term
Definition:The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.
Synonyms:exact_synonym: ACTH secretion;   adrenocorticotropic hormone secretion;   adrenotropic hormone secretion;   adrenotropin secretion;   corticotropic hormone secretion
 related_synonym: adrenocorticotropin secretion



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corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 acts_upstream_of_or_within ISO MGI:1857807 (MGI:3805139|PMID:18511498) RGD PMID:18511498 MGI:3805139 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:1267130|PMID:9655498)
UniProt
RGD
PMID:9655498 GO_REF:0000024 MGI:1267130 NCBI chr10:89,040,203...89,083,481
Ensembl chr10:89,040,203...89,083,481
JBrowse link
negative regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhbp corticotropin releasing hormone binding protein involved_in IEA
IDA
IBA
ISO
GO_REF:0000107
PMID:1846945
PMID:21873635
(PMID:1846945)
Ensembl
RGD
PMID:1846945 PMID:1846945 PMID:21873635 GO_REF:0000107, RGD:69816, RGD:13792537 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
JBrowse link
positive regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin IMP RGD PMID:16896162 RGD:1626228 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391
JBrowse link
G Crh corticotropin releasing hormone involved_in IDA
ISO
IMP
(PMID:11329063) RGD PMID:11329063 PMID:7477349 PMID:20663987 RGD:70047, RGD:5508201 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Ecrg4 ECRG4 augurin precursor involved_in ISO UniProtKB:D4A540:PRO_0000415564 (PMID:20233222) RGD PMID:20233222 NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:12566947) RGD PMID:12566947 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Lif LIF, interleukin 6 family cytokine IDA RGD PMID:20160138 RGD:2326054 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Pex5l peroxisomal biogenesis factor 5-like IDA RGD PMID:11278749 RGD:737646 NCBI chr 2:115,694,868...115,908,338
Ensembl chr 2:115,700,972...115,913,628
JBrowse link
G Rab8b RAB8B, member RAS oncogene family IDA RGD PMID:11278749 RGD:737646 NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384
JBrowse link
G Ucn urocortin involved_in IDA
ISO
(PMID:11329063) RGD PMID:11329063 PMID:7477349 RGD:70047 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1a arginine vasopressin receptor 1A involved_in NAS PMID:1560825 UniProt PMID:1560825 RGD:1298691 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Crhbp corticotropin releasing hormone binding protein involved_in ISO
ISS
(PMID:13150566)
GO_REF:0000024
RGD
UniProt
PMID:13150566 GO_REF:0000024 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    multicellular organismal process 8976
      system process 3391
        endocrine process 112
          endocrine hormone secretion 71
            corticotropin secretion 12
              negative regulation of corticotropin secretion 1
              positive regulation of corticotropin secretion 8
              regulation of corticotropin secretion + 10
Path 2
Term Annotations click to browse term
  biological_process 19497
    localization 6488
      establishment of localization 4887
        transport 4725
          nitrogen compound transport 2066
            amide transport 382
              peptide transport 341
                peptide secretion 319
                  peptide hormone secretion 311
                    corticotropin secretion 12
                      negative regulation of corticotropin secretion 1
                      positive regulation of corticotropin secretion 8
                      regulation of corticotropin secretion + 10
paths to the root