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ONTOLOGY REPORT - ANNOTATIONS

Term:corticotropin secretion
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Accession:GO:0051458 term browser browse the term
Definition:The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.
Synonyms:exact_synonym: ACTH secretion;   adrenocorticotropic hormone secretion;   adrenotropic hormone secretion;   adrenotropin secretion;   corticotropic hormone secretion
 related_synonym: adrenocorticotropin secretion


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corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 acts_upstream_of_or_within ISO MGI:1857807 (PMID:18511498) RGD PMID:18511498 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:1267130|PMID:9655498)		 UniProt
Ensembl
RGD		 PMID:9655498 GO_REF:0000024 GO_REF:0000107 MGI:1267130 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
negative regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhbp corticotropin releasing hormone binding protein involved_in IEA
ISO
IDA
IBA		 GO_REF:0000107
(PMID:1846945)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:1846945 PMID:1846945 GO_REF:0000033 GO_REF:0000107, RGD:69816 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
positive regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin IMP RGD PMID:16896162 RGD:1626228 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Crh corticotropin releasing hormone involved_in IDA
IMP
ISO		 (PMID:11329063) RGD PMID:11329063 PMID:7477349 PMID:20663987 RGD:70047, RGD:5508201 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Ecrg4 ECRG4 augurin precursor involved_in ISO UniProtKB:D4A540-PRO_0000415564 (PMID:20233222) RGD PMID:20233222 NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:12566947) RGD PMID:12566947 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Lif LIF, interleukin 6 family cytokine IDA RGD PMID:20160138 RGD:2326054 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Pex5l peroxisomal biogenesis factor 5-like IDA RGD PMID:11278749 RGD:737646 NCBI chr 2:115,694,868...115,908,365
Ensembl chr 2:115,700,972...115,913,628 		JBrowse link
G Rab8b RAB8B, member RAS oncogene family IDA RGD PMID:11278749 RGD:737646 NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384 		JBrowse link
G Ucn urocortin involved_in IDA
ISO		 (PMID:11329063) RGD PMID:11329063 PMID:7477349 RGD:70047 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
regulation of corticotropin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1a arginine vasopressin receptor 1A involved_in NAS PMID:1560825 UniProt PMID:1560825 RGD:1298691 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein involved_in ISO
ISS		 (PMID:13150566)
GO_REF:0000024		 RGD
UniProt		 PMID:13150566 GO_REF:0000024 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    multicellular organismal process 8865
      system process 3531
        endocrine process 121
          endocrine hormone secretion 79
            corticotropin secretion 12
              negative regulation of corticotropin secretion 1
              positive regulation of corticotropin secretion 8
              regulation of corticotropin secretion + 10
Path 2
Term Annotations click to browse term
  biological_process 20115
    localization 5683
      establishment of localization 4990
        transport 4684
          secretion 1208
            secretion by cell 1013
              signal release 649
                hormone secretion 422
                  endocrine hormone secretion 79
                    corticotropin secretion 12
                      negative regulation of corticotropin secretion 1
                      positive regulation of corticotropin secretion 8
                      regulation of corticotropin secretion + 10
paths to the root