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ONTOLOGY REPORT - ANNOTATIONS

Term:corticotropin-releasing hormone receptor binding
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Accession:GO:0051429 term browser browse the term
Definition:Binding to a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.
Synonyms:exact_synonym: CRF receptor binding;   CRH receptor binding;   CRHR binding;   corticotropin releasing factor receptor binding
 narrow_synonym: corticotropin releasing factor receptor ligand
 alt_id: GO:0031742


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corticotropin-releasing hormone receptor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ucn2 urocortin 2 enables ISO
IBA
ISS		 UniProtKB:Q13324 (PMID:11329063)
GO_REF:0000033		 RGD
GO_Central		 PMID:11329063 PMID:11329063 GO_REF:0000033, RGD:8553246 NCBI chr 8:109,637,624...109,639,173
Ensembl chr 8:109,638,285...109,639,172 		JBrowse link
G Ucn3 urocortin 3 enables ISO
IBA		 UniProtKB:Q13324 (PMID:11329063)
GO_REF:0000033		 RGD
GO_Central		 PMID:11329063 GO_REF:0000033 NCBI chr17:66,309,748...66,315,996
Ensembl chr17:66,309,371...66,315,990 		JBrowse link
corticotropin-releasing hormone receptor 1 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA
IPI		 RGD PMID:12942143 PMID:7477349 RGD:1358326, RGD:70047 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Gnao1 G protein subunit alpha o1 enables IPI
IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central
RGD		 PMID:20548297 GO_REF:0000033 GO_REF:0000118, RGD:5491170 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnas GNAS complex locus enables IPI
IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central
RGD		 PMID:20548297 GO_REF:0000033 GO_REF:0000118, RGD:5491170 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Ucn urocortin IPI RGD PMID:15049707 RGD:5490990 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
corticotropin-releasing hormone receptor 2 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA
IPI		 RGD PMID:12942143 PMID:11572971 PMID:15223302 RGD:1358326, RGD:5508795, RGD:5508815 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Ucn urocortin IPI RGD PMID:7477349 RGD:70047 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
G Ucn2 urocortin 2 enables IPI
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:19334530 GO_REF:0000002, RGD:5130955 NCBI chr 8:109,637,624...109,639,173
Ensembl chr 8:109,638,285...109,639,172 		JBrowse link
G Ucn3 urocortin 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:66,309,748...66,315,996
Ensembl chr17:66,309,371...66,315,990 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    binding 18037
      protein binding 14764
        signaling receptor binding 1640
          G protein-coupled receptor binding 322
            neuropeptide receptor binding 37
              corticotropin-releasing hormone receptor binding 6
                corticotropin-releasing hormone receptor 1 binding 4
                corticotropin-releasing hormone receptor 2 binding 4
paths to the root