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ONTOLOGY REPORT - ANNOTATIONS


Term:serotonin binding
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Accession:GO:0051378 term browser browse the term
Definition:Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Synonyms:exact_synonym: 5-hydroxytryptamine binding


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serotonin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A enables IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:8271204, PMID:21873635 RGD:2303617, RGD:13792537 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B enables IBA
ISO
PMID:21873635
(MGI:4821070|PMID:17325130)
RGD PMID:17325130, PMID:21873635 MGI:4821070, RGD:13792537 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D enables IBA
ISO
PMID:21873635
(MGI:48584|PMID:1557407)
RGD PMID:1557407, PMID:21873635 MGI:48584, RGD:13792537 NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F enables IBA
ISO
PMID:21873635
(PMID:8380639)
RGD PMID:8380639, PMID:21873635 RGD:13792537 NCBI chr11:1,982,113...1,983,513
Ensembl chr11:1,982,113...1,983,513
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A enables ISO (PMID:15862800)
(PMID:15831837), (PMID:15862800), (PMID:18703043), (PMID:19057895), (PMID:7582481)
RGD PMID:7582481 PMID:15831837 PMID:15862800 PMID:18703043 PMID:19057895 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B enables IDA
ISO
ISS
IEA
(PMID:12970106), (PMID:15625277), (PMID:15831837), (PMID:15862800), (PMID:17609583), (PMID:18703043), (PMID:19057895), (PMID:19307114), (PMID:7582481), (PMID:7926008)
(MGI:4821070|PMID:17325130)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:7582481 PMID:7926008 PMID:12970106 PMID:15625277 PMID:15831837 PMID:15862800 PMID:17325130 PMID:17609583 PMID:18703043 PMID:19057895 PMID:19307114, PMID:1505525 GO_REF:0000024 GO_REF:0000107 MGI:4821070, RGD:61633 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C enables ISO (PMID:12970106), (PMID:15831837), (PMID:18703043), (PMID:19057895), (PMID:7582481) RGD PMID:7582481 PMID:12970106 PMID:15831837 PMID:18703043 PMID:19057895 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A enables ISO (PMID:7565620) RGD PMID:7565620 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:57,637,013...57,820,317
Ensembl chr18:57,654,290...57,819,698
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:199,916...209,599
Ensembl chr 4:199,916...209,599
JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:37,479,758...37,492,680
Ensembl chr13:37,479,758...37,492,680
JBrowse link
G Maoa monoamine oxidase A IDA
IMP
Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741, PMID:11754741, PMID:11263670 RGD:1600709, RGD:1600709, RGD:1600713 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Slc6a4 solute carrier family 6 member 4 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20083
    binding 17058
      amine binding 15
        serotonin binding 13
Path 2
Term Annotations click to browse term
  molecular_function 20083
    binding 17058
      ion binding 5274
        cation binding 3534
          serotonin binding 13
paths to the root