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ONTOLOGY REPORT - ANNOTATIONS


Term:serotonin binding
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Accession:GO:0051378 term browser browse the term
Definition:Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Synonyms:exact_synonym: 5-hydroxytryptamine binding



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serotonin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd4 dopamine receptor D4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A enables IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:8271204 GO_REF:0000033, RGD:2303617 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B enables ISO (MGI:4821070|PMID:17325130) RGD PMID:17325130 MGI:4821070 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D enables ISO (PMID:1557407) RGD PMID:1557407 NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F enables ISO
IEA
(PMID:8380639)
GO_REF:0000107
RGD
Ensembl
PMID:8380639 GO_REF:0000107 NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A enables ISO (PMID:15862800)
(PMID:15831837), (PMID:15862800), (PMID:18703043), (PMID:19057895), (PMID:7582481)
RGD PMID:7582481 PMID:15831837 PMID:15862800 PMID:18703043 PMID:19057895 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B enables IDA
IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:4821070|PMID:17325130)
(PMID:12970106), (PMID:15625277), (PMID:15831837), (PMID:15862800), (PMID:17609583), (PMID:18703043), (PMID:19057895), (PMID:19307114), (PMID:7582481), (PMID:7926008)
(PMID:15862800)
Ensembl
UniProt
RGD
PMID:7582481 PMID:7926008 PMID:12970106 PMID:15625277 PMID:15831837 More... GO_REF:0000024 GO_REF:0000107 MGI:4821070, RGD:61633 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C enables ISO (PMID:12970106), (PMID:15831837), (PMID:18703043), (PMID:19057895), (PMID:7582481) RGD PMID:7582481 PMID:12970106 PMID:15831837 PMID:18703043 PMID:19057895 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A enables ISO
IEA
(PMID:7565620)
GO_REF:0000107
RGD
Ensembl
PMID:7565620 GO_REF:0000107 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651
JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835
JBrowse link
G Maoa monoamine oxidase A IDA
IMP
Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741 PMID:11754741 PMID:11263670 RGD:1600709, RGD:1600709, RGD:1600713 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Slc6a4 solute carrier family 6 member 4 enables ISO
ISS
IBA
(PMID:34851672)
GO_REF:0000024
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:34851672 GO_REF:0000024 GO_REF:0000033 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    binding 17950
      amine binding 23
        serotonin binding 13
Path 2
Term Annotations click to browse term
  molecular_function 20890
    binding 17950
      small molecule binding 6151
        ion binding 5860
          cation binding 4037
            serotonin binding 13
paths to the root