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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of lyase activity
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Accession:GO:0051349 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
Synonyms:exact_synonym: lyase activator;   up regulation of lyase activity;   upregulation of lyase activity
 narrow_synonym: activation of lyase activity;   stimulation of lyase activity



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positive regulation of lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftmt ferritin mitochondrial involved_in ISO (PMID:18160053) RGD PMID:18160053 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
JBrowse link
G Fxn frataxin involved_in ISO (PMID:18160053), (PMID:20053667) RGD PMID:18160053 PMID:20053667 NCBI chr 1:221,874,007...221,897,841
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
activation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acr acrosin involved_in ISS
ISO
GO_REF:0000024
(PMID:3880736)
UniProt
RGD
PMID:3880736 GO_REF:0000024 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474
JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in ISO (PMID:15123695) RGD PMID:15123695 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 involved_in ISO
ISS
(PMID:15123695)
GO_REF:0000024
RGD
HGNC-UCL
PMID:15123695 GO_REF:0000024 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in
acts_upstream_of_or_within
ISO (PMID:10822112), (PMID:16014619)
(MGI:77881|PMID:8582325)
RGD PMID:8582325 PMID:10822112 PMID:16014619 MGI:77881 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calcr calcitonin receptor NOT|involved_in ISO (PMID:15563840) RGD PMID:15563840 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392
JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2450485|PMID:12488442)
(PMID:2168520)
Ensembl
RGD
PMID:2168520 PMID:12488442 GO_REF:0000107 MGI:2450485 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Fshr follicle stimulating hormone receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Ghrhr growth hormone releasing hormone receptor IDA RGD PMID:9845677 RGD:1601338 NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776
JBrowse link
G Gnal G protein subunit alpha L acts_upstream_of_or_within ISO (MGI:2450485|PMID:12488442) RGD PMID:12488442 MGI:2450485 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor involved_in IDA
IEA
ISO
IBA
GO_REF:0000107
(MGI:5318037|PMID:10493819)
PMID:21873635
Ensembl
RGD
PMID:10493819 PMID:8440169 PMID:21873635 GO_REF:0000107 MGI:5318037, RGD:2292602, RGD:13792537 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:15385642) RGD PMID:15385642 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rxfp1 relaxin family peptide receptor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:164,772,270...164,893,484
Ensembl chr 2:164,774,799...164,893,412
JBrowse link
G Rxfp2 relaxin family peptide receptor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:4,925,722...4,986,596
Ensembl chr12:4,925,722...4,986,596
JBrowse link
G Tshr thyroid stimulating hormone receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 IDA RGD PMID:8224221 RGD:70054 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597
JBrowse link
positive regulation of aconitate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftmt ferritin mitochondrial involved_in ISO UniProtKB:Q16595 (PMID:18160053) RGD PMID:18160053 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
JBrowse link
G Fxn frataxin involved_in ISO
IEA
(PMID:18160053)
GO_REF:0000107
RGD
Ensembl
PMID:18160053 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,841
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150
JBrowse link
positive regulation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:21143600 RGD:8693686 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Akap5 A-kinase anchoring protein 5 involved_in IDA
IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro
RGD
PMID:20410303 PMID:21873635 GO_REF:0000002, RGD:7242424, RGD:13792537 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISS
ISO
GO_REF:0000024
(MGI:6243790|PMID:24086669)
UniProt
RGD
PMID:24086669 GO_REF:0000024 MGI:6243790 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in ISS
ISO
GO_REF:0000024
(MGI:6243790|PMID:24086669)
UniProt
RGD
PMID:24086669 GO_REF:0000024 MGI:6243790 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Calcr calcitonin receptor involved_in ISO (PMID:7588285), (PMID:7769107)
(PMID:7769107)
RGD PMID:7588285 PMID:7769107 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392
JBrowse link
G Gcg glucagon ISO RGD RGD:11556254 RGD:150520179 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
MGI:1857444 (MGI:3628716|PMID:11788835)
HGNC-UCL
Ensembl
RGD
PMID:11788835 GO_REF:0000024 GO_REF:0000107 MGI:3628716 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 involved_in ISO
ISS
IEA
(PMID:19171672)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:19171672 GO_REF:0000024 GO_REF:0000107 NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405
JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISO
ISS
(PMID:19171672)
GO_REF:0000024
RGD
UniProt
PMID:19171672 GO_REF:0000024 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IMP RGD PMID:15901773 RGD:1598578 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3773754 (MGI:3794903|PMID:18340377)
Ensembl
RGD
PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Guca1a guanylate cyclase activator 1A acts_upstream_of_or_within IDA
ISO
(MGI:2664110|PMID:11493703) RGD PMID:11493703 PMID:12545196 MGI:2664110, RGD:1599357 NCBI chr 9:13,587,695...13,598,566
Ensembl chr 9:13,588,525...13,598,565
JBrowse link
G Guca1b guanylate cyclase activator 1B acts_upstream_of_or_within ISO (MGI:2664110|PMID:11493703) RGD PMID:11493703 MGI:2664110 NCBI chr 9:13,599,619...13,607,455
Ensembl chr 9:13,599,619...13,607,455
JBrowse link
G Nos1 nitric oxide synthase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:17502619)
Ensembl
RGD
PMID:17502619 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
positive regulation of L-dopa decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
GO_REF:0000024
(PMID:19703902)
ParkinsonsUK-UCL
RGD
PMID:19703902 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    biological regulation 13573
      regulation of molecular function 2736
        positive regulation of molecular function 1557
          positive regulation of catalytic activity 1113
            positive regulation of lyase activity 35
              positive regulation of L-dopa decarboxylase activity 1
              positive regulation of aconitate hydratase activity 3
              positive regulation of adenylate cyclase activity + 25
              positive regulation of cystathionine beta-synthase activity 0
              positive regulation of guanylate cyclase activity 6
paths to the root