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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of transferase activity
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Accession:GO:0051348 term browser browse the term
Definition:Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
Comment:This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
Synonyms:exact_synonym: down regulation of transferase activity;   downregulation of transferase activity;   transferase inhibitor
 narrow_synonym: inhibition of transferase activity


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negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 ISO RGD PMID:10721722 RGD:632478 NCBI chr 9:120,388,875...120,580,167
Ensembl chr 9:120,388,875...120,580,170 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 ISO RGD PMID:10721722 RGD:632478 NCBI chr17:47,967,904...47,981,781
Ensembl chr17:47,967,810...47,981,781 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:22584582 RGD:10045364 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
negative regulation of hexokinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCKR glucokinase regulator ISO RGD PMID:14627435 RGD:1598592 NCBI chr 2:27,496,839...27,523,684
Ensembl chr 2:27,496,839...27,523,684 		JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 ISO RGD PMID:12064607 RGD:1299562 NCBI chr11:45,885,651...45,906,465
Ensembl chr11:45,885,651...45,906,465 		JBrowse link
negative regulation of kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSK C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:19762078 RGD:150429972 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G PRPSAP1 phosphoribosyl pyrophosphate synthetase associated protein 1 ISO RGD PMID:9366267 RGD:5134981 NCBI chr17:76,309,478...76,354,198
Ensembl chr17:76,309,478...76,384,521 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 ISO due to an autoinhibitory domain RGD PMID:15081430 RGD:2298791 NCBI chr12:752,579...911,452
Ensembl chr12:752,579...911,452 		JBrowse link
negative regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:17182785 RGD:2301767 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 ISO RGD PMID:12933696 RGD:1626126 NCBI chr11:72,223,563...72,239,147
Ensembl chr11:72,223,701...72,239,147 		JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:9857190 RGD:10044039 NCBI chr11:18,727,928...18,792,721
Ensembl chr11:18,727,928...18,792,721 		JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:14612383 RGD:1580517 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491 		JBrowse link
negative regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO in PC12 cells, PKCzeta deactivated after long-term activation of Adora2a RGD PMID:12590138 RGD:1625697 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:17289031 RGD:9587773 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12688394 RGD:1581394 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:12688394 RGD:1581394 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO RGD PMID:21668448 RGD:10401931 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G IL6 interleukin 6 ISO Phospholamban phosphorylation RGD PMID:15845578 RGD:2306941 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ILK integrin linked kinase ISO GSK-3 activity as a Tau protein kinase RGD PMID:12629168 RGD:2302091 NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874 		JBrowse link
G PCP4 Purkinje cell protein 4 ISO RGD PMID:10751438 RGD:1579763 NCBI chr21:39,867,438...39,929,392
Ensembl chr21:39,867,438...39,929,397 		JBrowse link
G RGN regucalcin ISO RGD PMID:11455566 RGD:9590207 NCBI chr  X:47,078,443...47,093,313
Ensembl chr  X:47,078,355...47,093,314 		JBrowse link
negative regulation of telomerase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARG peroxisome proliferator activated receptor gamma ISO RGD PMID:16556873 RGD:1580657 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    biological regulation 13397
      regulation of molecular function 307
        negative regulation of molecular function 121
          negative regulation of catalytic activity 71
            negative regulation of transferase activity 23
              negative regulation of ATP citrate synthase activity 0
              negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity 0
              negative regulation of CoA-transferase activity 0
              negative regulation of DNA primase activity 0
              negative regulation of DNA-directed DNA polymerase activity 0
              negative regulation of NAD+ ADP-ribosyltransferase activity 0
              negative regulation of RNA polymerase III activity 0
              negative regulation of RNA-dependent RNA polymerase activity 0
              negative regulation of SUMO transferase activity 0
              negative regulation of alpha-(1->3)-fucosyltransferase activity 0
              negative regulation of choline O-acetyltransferase activity 0
              negative regulation of glucuronosyltransferase activity 0
              negative regulation of glycogen (starch) synthase activity 0
              negative regulation of glycogen synthase activity, transferring glucose-1-phosphate 0
              negative regulation of kinase activity + 22
              negative regulation of polynucleotide adenylyltransferase activity 0
              negative regulation of protein ADP-ribosylation 0
              negative regulation of protein-glutamine gamma-glutamyltransferase activity 0
              negative regulation of pyruvate kinase activity 0
              negative regulation of serine C-palmitoyltransferase activity 0
              negative regulation of telomerase activity + 1
              negative regulation of ubiquitin-protein transferase activity + 0
paths to the root