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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cyclic-nucleotide phosphodiesterase activity
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Accession:GO:0051342 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
Synonyms:exact_synonym: 3',5' cyclic nucleotide phosphodiesterase regulator;   regulation of 3',5' cyclic nucleotide phosphodiesterase activity
 narrow_synonym: 3',5'-cyclic-AMP phosphodiesterase regulator;   cAMP phosphodiesterase regulator;   regulation of 3',5'-cyclic-AMP phosphodiesterase activity;   regulation of cAMP phosphodiesterase activity;   regulation of cGMP phosphodiesterase activity
 related_synonym: phosphodiesterase regulator



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negative regulation of cyclic-nucleotide phosphodiesterase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aip aryl-hydrocarbon receptor-interacting protein IDA RGD PMID:12810716 RGD:632260 NCBI chr 1:201,407,287...201,419,220
Ensembl chr 1:201,407,288...201,419,122
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 involved_in IDA
IMP
PMID:22975349 RGD
BHF-UCL
PMID:22975349 PMID:22975349 RGD:8554232, RGD:8554232 NCBI chr19:52,867,914...52,907,169
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Rgn regucalcin IDA RGD PMID:1656206 RGD:9590243 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (MGI:4950776|PMID:21445361) RGD PMID:21445361 MGI:4950776 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
JBrowse link
positive regulation of cyclic-nucleotide phosphodiesterase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in ISO (PMID:8631777) RGD PMID:8631777 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:8631777) RGD PMID:8631777 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:8631777) RGD PMID:8631777 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 IDA RGD PMID:7878085 RGD:1599022 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:20819076) RGD PMID:20819076 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link

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Term Annotations click to browse term
  biological_process 20050
    biological regulation 13942
      regulation of molecular function 3225
        regulation of catalytic activity 2420
          regulation of hydrolase activity 1093
            regulation of cyclic-nucleotide phosphodiesterase activity 9
              negative regulation of cyclic-nucleotide phosphodiesterase activity 4
              positive regulation of cyclic-nucleotide phosphodiesterase activity 5
paths to the root