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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of oxidoreductase activity
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Accession:GO:0051341 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Synonyms:exact_synonym: oxidoreductase regulator


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regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ECSIT ECSIT signaling integrator JBrowse link 2 70,154,861 70,170,762 RGD:14298760
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP27B1 25-hydroxyvitamin D3 1alpha-hydroxylase JBrowse link 5 23,053,129 23,058,865 RGD:14298760
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 4 124,619,887 124,629,638 RGD:14298760
G NFKB1 nuclear factor kappa B subunit 1 JBrowse link 8 118,391,010 118,478,927 RGD:14298760
negative regulation of electron transfer activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase JBrowse link 5 42,568,131 42,575,983 RGD:9068941
negative regulation of monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 8 129,247,724 129,388,307 RGD:14298760
negative regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DRD5 dopamine receptor D5 JBrowse link 8 6,180,221 6,182,575 RGD:14298760
G IL13 interleukin 13 JBrowse link 2 134,972,099 134,976,672 RGD:9068941
G INS insulin JBrowse link 2 1,496,842 1,498,052 RGD:14298760
negative regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG2 arginase 2 JBrowse link 7 91,343,987 91,385,911 RGD:9068941
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 9 64,336,354 64,445,669 RGD:14298760
G CAV1 caveolin 1 JBrowse link 18 29,648,120 29,682,451 RGD:14298760
G CAV3 caveolin 3 JBrowse link 13 65,117,868 65,130,886 RGD:14298760
G CNR1 cannabinoid receptor 1 JBrowse link 1 56,466,022 56,493,275 RGD:9068941
G CNR2 cannabinoid receptor 2 JBrowse link 6 81,659,162 81,692,550 RGD:9068941
G ENG endoglin JBrowse link 1 268,309,379 268,343,861 RGD:9068941
G GLA galactosidase alpha JBrowse link X 83,024,582 83,032,273 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 13 140,136,109 140,370,197 RGD:9068941
G NOSIP nitric oxide synthase interacting protein JBrowse link 6 54,618,977 54,636,031 RGD:9068941
negative regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) JBrowse link 16 34,262,495 34,272,084 RGD:14298760
G GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) JBrowse link 16 34,282,160 34,290,422 RGD:14298760
G HP haptoglobin JBrowse link 6 14,980,382 14,985,245 RGD:9068941
G MT3 metallothionein 3 JBrowse link 6 18,634,735 18,636,134 RGD:14298760
G OXA1L OXA1L mitochondrial inner membrane protein JBrowse link 7 76,234,710 76,266,700 RGD:9068941
G PRDX5 peroxiredoxin 5 JBrowse link 2 7,798,672 7,801,955 RGD:9068941
G SLC4A1 solute carrier family 4 member 1 JBrowse link 12 18,957,813 18,975,266 RGD:14298760
G TMLHE trimethyllysine hydroxylase, epsilon JBrowse link X 125,601,920 125,673,716 RGD:9068941
negative regulation of peroxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
negative regulation of primary amine oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100520329 membrane primary amine oxidase JBrowse link 12 20,013,616 20,021,507 RGD:14298760
G LOC110256000 membrane primary amine oxidase-like JBrowse link 12 19,996,324 20,007,006 RGD:14298760
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 5,698,508 6,731,132 RGD:14298760
negative regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCKDK branched chain keto acid dehydrogenase kinase JBrowse link 3 17,375,628 17,380,925 RGD:14298760
G PDK1 pyruvate dehydrogenase kinase 1 JBrowse link 15 78,608,394 78,650,958 RGD:14298760
G PDK2 pyruvate dehydrogenase kinase 2 JBrowse link 12 26,274,562 26,295,787 RGD:14298760
G PDK3 pyruvate dehydrogenase kinase 3 JBrowse link X 20,486,205 20,598,492 RGD:14298760
G PDK4 pyruvate dehydrogenase kinase 4 JBrowse link 9 75,246,956 75,260,134 RGD:14298760
negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LRRK2 leucine rich repeat kinase 2 JBrowse link 5 71,800,337 71,945,828 RGD:14298760
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNG interferon gamma JBrowse link 5 32,477,906 32,482,670 RGD:14298760
G LOC110258578 interleukin-1 beta-like RGD:9068941
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:14298760
positive regulation of catalase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT3 sirtuin 3 JBrowse link 2 38,465 55,074 RGD:9068941
positive regulation of cytochrome-c oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 14 90,859,209 90,907,084 RGD:9068941
G APOPT1 apoptogenic 1, mitochondrial RGD:9068941
G ATP7A ATPase copper transporting alpha JBrowse link X 61,972,544 62,110,058 RGD:9068941
G COX17 cytochrome c oxidase copper chaperone COX17 JBrowse link 13 140,584,286 140,594,636 RGD:14298760
positive regulation of glutathione peroxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 8 129,247,724 129,388,307 RGD:14298760
positive regulation of monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GDNF glial cell derived neurotrophic factor JBrowse link 16 22,936,602 22,965,929 RGD:14298760
G POR P450 (cytochrome) oxidoreductase JBrowse link 3 10,212,734 10,272,184 RGD:14298760
positive regulation of monophenol monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDH3 cadherin 3 JBrowse link 6 18,190,971 18,236,184 RGD:14298760
positive regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYBA cytochrome b-245 alpha chain JBrowse link 6 1,015,212 1,021,422 RGD:9068941
G GNAI2 G protein subunit alpha i2 JBrowse link 13 32,705,326 32,733,804 RGD:9068941
G GNAI3 G protein subunit alpha i3 JBrowse link 4 110,527,363 110,579,331 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
G RFK riboflavin kinase JBrowse link 1 229,330,457 229,337,077 RGD:9068941
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGTR2 angiotensin II receptor type 2 JBrowse link X 95,267,709 95,272,237 RGD:14298760
G AKT1 AKT serine/threonine kinase 1 RGD:9068941
G APOE apolipoprotein E JBrowse link 6 51,373,113 51,375,333 RGD:14298760
G CALM1 calmodulin 1 JBrowse link 7 112,160,823 112,171,754 RGD:9068941
G CALM2 calmodulin 2 JBrowse link 3 93,371,765 93,386,378 RGD:9068941
G CALM3 calmodulin 3 JBrowse link 6 52,506,979 52,516,704 RGD:9068941
G DHFR dihydrofolate reductase JBrowse link 2 89,230,660 89,255,830 RGD:14298760
G ESR1 estrogen receptor 1 JBrowse link 1 14,217,032 14,604,906 RGD:14298760
G FCER2 Fc fragment of IgE receptor II JBrowse link 2 71,454,046 71,468,149 RGD:14298760
G GCH1 GTP cyclohydrolase 1 JBrowse link 1 184,201,232 184,264,060 RGD:14298760
G HTR2B 5-hydroxytryptamine receptor 2B JBrowse link 15 131,844,578 131,860,417 RGD:14298760
G KRAS KRAS proto-oncogene, GTPase JBrowse link 5 48,508,774 48,546,260 RGD:9068941
G NOD1 nucleotide binding oligomerization domain containing 1 JBrowse link 18 42,464,667 42,509,135 RGD:9068941
G NPR3 natriuretic peptide receptor 3 JBrowse link 16 18,841,540 18,929,813 RGD:9068941
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit JBrowse link 1 44,156,771 44,186,224 RGD:14298760
G PTK2B protein tyrosine kinase 2 beta JBrowse link 14 11,063,662 11,194,196 RGD:14298760
G S100A1 S100 calcium binding protein A1 JBrowse link 4 96,007,026 96,012,305 RGD:9068941
G SCARB1 scavenger receptor class B member 1 JBrowse link 14 28,301,421 28,393,568 RGD:14298760
G TERF2 telomeric repeat binding factor 2 JBrowse link 6 17,605,748 17,631,795 RGD:14298760
G TERT telomerase reverse transcriptase JBrowse link 16 79,258,591 79,276,421 RGD:14298760
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:9068941
positive regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 1 270,761,641 270,906,708 RGD:14298760
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 9 120,888,891 120,984,724 RGD:14298760
G ATP7A ATPase copper transporting alpha JBrowse link X 61,972,544 62,110,058 RGD:14298760
G CCS copper chaperone for superoxide dismutase JBrowse link 2 5,819,471 5,833,263 RGD:14298760
G FDX1 ferredoxin 1 JBrowse link 9 38,376,147 38,399,026 RGD:9068941
G LGALS9 galectin 9 JBrowse link 12 44,155,079 44,173,634 RGD:9068941
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 6 34,132,127 34,167,446 RGD:9068941
G RIPK3 receptor interacting serine/threonine kinase 3 JBrowse link 7 74,951,145 74,955,255 RGD:14298760
positive regulation of prostaglandin-endoperoxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EDN1 endothelin 1 JBrowse link 7 8,752,018 8,758,354 RGD:14298760
G EDN2 endothelin 2 JBrowse link 6 169,751,956 169,758,011 RGD:14298760
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 6 34,132,127 34,167,446 RGD:9068941
positive regulation of pyrroline-5-carboxylate reductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
positive regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 JBrowse link 4 42,769,232 42,777,936 RGD:14298760
G PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 JBrowse link 6 27,565,423 27,572,868 RGD:14298760
positive regulation of succinate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FTMT ferritin mitochondrial JBrowse link 2 125,391,524 125,395,066 RGD:14298760
G FXN frataxin JBrowse link 1 222,412,485 222,433,224 RGD:9068941
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 61,972,544 62,110,058 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
G RGN regucalcin JBrowse link X 41,725,660 41,749,736 RGD:9068941
G SIRT3 sirtuin 3 JBrowse link 2 38,465 55,074 RGD:9068941
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:14298760
positive regulation of tyrosine 3-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
positive regulation of vitamin D 24-hydroxylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP27B1 25-hydroxyvitamin D3 1alpha-hydroxylase JBrowse link 5 23,053,129 23,058,865 RGD:14298760
G FGF23 fibroblast growth factor 23 JBrowse link 5 66,028,591 66,038,078 RGD:14298760
G VDR vitamin D receptor JBrowse link 5 78,205,807 78,266,505 RGD:14298760
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VDR vitamin D receptor JBrowse link 5 78,205,807 78,266,505 RGD:14298760
regulation of cytochrome-c oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 61,972,544 62,110,058 RGD:9068941
G PHB2 prohibitin 2 JBrowse link 5 63,751,566 63,756,480 RGD:14298760
G SPHK2 sphingosine kinase 2 JBrowse link 6 53,982,911 53,986,779 RGD:14298760
G TACO1 translational activator of cytochrome c oxidase I JBrowse link 12 15,308,309 15,312,906 RGD:14298760
regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLAMF8 SLAM family member 8 JBrowse link 4 90,661,984 90,673,044 RGD:9068941
regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACVR2A activin A receptor type 2A JBrowse link 15 4,177,333 4,259,056 RGD:14298760
G EGFR epidermal growth factor receptor JBrowse link 9 139,302,410 139,474,632 RGD:14298760
G IL1A interleukin 1 alpha JBrowse link 3 43,718,320 43,731,668 RGD:14298760
G IL1B interleukin 1 beta JBrowse link 3 43,670,126 43,677,125 RGD:14298760
G IL1B2 interleukin 1, beta 2 RGD:14298760
G LEP leptin JBrowse link 18 20,106,867 20,124,071 RGD:14298760
G LOC110255300 interleukin-1 beta-like RGD:14298760
G LOC110258125 interleukin-1 beta-like RGD:14298760
G LOC110258578 interleukin-1 beta-like RGD:14298760
G LOC110258579 interleukin-1 beta-like RGD:14298760
regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT4 sirtuin 4 JBrowse link 14 40,290,288 40,303,887 RGD:14298760
regulation of succinate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT5 sirtuin 5 JBrowse link 7 9,951,024 9,968,004 RGD:14298760
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 6 167,811,589 167,861,321 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16411
    metabolic process 10434
      regulation of metabolic process 6357
        regulation of oxidoreductase activity 105
          negative regulation of oxidoreductase activity + 36
          positive regulation of oxidoreductase activity + 54
          regulation of D-amino-acid oxidase activity + 0
          regulation of NAD(P)H oxidase activity + 9
          regulation of cytokinin dehydrogenase activity + 0
          regulation of electron transfer activity + 8
          regulation of heme oxygenase activity + 0
          regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity + 0
          regulation of malate dehydrogenase (decarboxylating) (NADP+) activity + 0
          regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity + 0
          regulation of monooxygenase activity + 52
          regulation of peroxidase activity + 4
          regulation of prostaglandin-endoperoxide synthase activity + 3
          regulation of pyrroline-5-carboxylate reductase activity + 1
          regulation of pyruvate dehydrogenase activity + 8
          regulation of ribonucleoside-diphosphate reductase activity + 0
          regulation of succinate dehydrogenase activity + 3
          regulation of superoxide dismutase activity + 6
Path 2
Term Annotations click to browse term
  biological_process 16411
    biological regulation 11881
      regulation of biological process 11312
        regulation of metabolic process 6357
          regulation of oxidoreductase activity 105
            negative regulation of oxidoreductase activity + 36
            positive regulation of oxidoreductase activity + 54
            regulation of D-amino-acid oxidase activity + 0
            regulation of NAD(P)H oxidase activity + 9
            regulation of cytokinin dehydrogenase activity + 0
            regulation of electron transfer activity + 8
            regulation of heme oxygenase activity + 0
            regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity + 0
            regulation of malate dehydrogenase (decarboxylating) (NADP+) activity + 0
            regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity + 0
            regulation of monooxygenase activity + 52
            regulation of peroxidase activity + 4
            regulation of prostaglandin-endoperoxide synthase activity + 3
            regulation of pyrroline-5-carboxylate reductase activity + 1
            regulation of pyruvate dehydrogenase activity + 8
            regulation of ribonucleoside-diphosphate reductase activity + 0
            regulation of succinate dehydrogenase activity + 3
            regulation of superoxide dismutase activity + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.