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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of oxidoreductase activity
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Accession:GO:0051341 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Synonyms:exact_synonym: oxidoreductase regulator


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regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ecsit ECSIT signalling integrator JBrowse link 9 22,071,435 22,086,296 RGD:2290270
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 10 127,048,246 127,054,884 RGD:2290270
G Gfi1 growth factor independent 1 transcription repressor JBrowse link 5 107,716,655 107,725,805 RGD:2290270
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:2290270
negative regulation of electron transfer activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Etfbkmt electron transfer flavoprotein beta subunit lysine methyltransferase JBrowse link 6 149,141,476 149,151,171 RGD:2290270
negative regulation of monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snca synuclein, alpha JBrowse link 6 60,731,573 60,829,855 RGD:2290270
negative regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd5 dopamine receptor D5 JBrowse link 5 38,319,509 38,322,523 RGD:2290270
G Il13 interleukin 13 JBrowse link 11 53,631,323 53,634,702 RGD:2290270
G Ins2 insulin II JBrowse link 7 142,678,656 142,679,726 RGD:2290270
negative regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase type II JBrowse link 12 79,130,788 79,156,301 RGD:2290270
G Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 JBrowse link 1 133,702,674 133,801,059 RGD:2290270
G Cav1 caveolin 1, caveolae protein JBrowse link 6 17,306,335 17,341,328 RGD:2290270
G Cav3 caveolin 3 JBrowse link 6 112,459,505 112,472,872 RGD:2290270
G Cnr1 cannabinoid receptor 1 (brain) JBrowse link 4 33,923,171 33,948,831 RGD:2290270
G Cnr2 cannabinoid receptor 2 (macrophage) JBrowse link 4 135,895,189 135,920,219 RGD:2290270
G Eng endoglin JBrowse link 2 32,646,595 32,682,669 RGD:2290270
G Gla galactosidase, alpha JBrowse link X 134,588,169 134,601,005 RGD:2290270
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 16 38,089,001 38,246,084 RGD:2290270
G Nosip nitric oxide synthase interacting protein JBrowse link 7 45,062,417 45,078,503 RGD:2290270
negative regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gzma granzyme A JBrowse link 13 113,093,824 113,100,981 RGD:2290270
G Hp haptoglobin JBrowse link 8 109,575,128 109,579,172 RGD:2290270
G Mt3 metallothionein 3 JBrowse link 8 94,152,607 94,154,148 RGD:9068941
G Oxa1l oxidase assembly 1-like JBrowse link 14 54,360,841 54,369,669 RGD:2290270
G Prdx5 peroxiredoxin 5 JBrowse link 19 6,906,697 6,910,106 RGD:2290270
G Slc4a1 solute carrier family 4 (anion exchanger), member 1 JBrowse link 11 102,348,820 102,365,281 RGD:2290270
G Tmlhe trimethyllysine hydroxylase, epsilon RGD:2290270
negative regulation of peroxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstp1 glutathione S-transferase, pi 1 JBrowse link 19 4,035,411 4,037,912 RGD:2290270
negative regulation of primary amine oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aoc3 amine oxidase, copper containing 3 JBrowse link 11 101,330,606 101,339,430 RGD:2290270
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 17 10,840,359 12,063,370 RGD:2290270
negative regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bckdk branched chain ketoacid dehydrogenase kinase JBrowse link 7 127,904,073 127,909,664 RGD:2290270
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 JBrowse link 2 71,873,215 71,903,858 RGD:2290270
G Pdk2 pyruvate dehydrogenase kinase, isoenzyme 2 JBrowse link 11 95,026,258 95,041,371 RGD:2290270
G Pdk3 pyruvate dehydrogenase kinase, isoenzyme 3 JBrowse link X 93,764,616 93,832,150 RGD:2290270
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 JBrowse link 6 5,483,351 5,496,278 RGD:2290270
negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 15 91,672,791 91,816,124 RGD:2290270
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:2290270
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
positive regulation of catalase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt3 sirtuin 3 JBrowse link 7 140,863,663 140,882,309 RGD:2290270
positive regulation of cytochrome-c oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 6 116,410,071 116,461,178 RGD:2290270
G Atp7a ATPase, Cu++ transporting, alpha polypeptide JBrowse link X 106,027,224 106,128,161 RGD:2290270
G Coa8 cytochrome c oxidase assembly factor 8 JBrowse link 12 111,713,268 111,755,057 RGD:2290270
G Cox17 cytochrome c oxidase assembly protein 17, copper chaperone JBrowse link 16 38,346,983 38,352,763 RGD:2290270
positive regulation of glutathione peroxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snca synuclein, alpha JBrowse link 6 60,731,573 60,829,855 RGD:2290270
positive regulation of monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gdnf glial cell line derived neurotrophic factor JBrowse link 15 7,810,048 7,837,580 RGD:2290270
G Por P450 (cytochrome) oxidoreductase JBrowse link 5 135,670,040 135,735,326 RGD:2290270
positive regulation of monophenol monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdh3 cadherin 3 JBrowse link 8 106,510,852 106,556,911 RGD:2290270
positive regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyba cytochrome b-245, alpha polypeptide JBrowse link 8 122,424,771 122,432,940 RGD:2290270
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 JBrowse link 9 107,614,125 107,635,391 RGD:2290270
G Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 JBrowse link 3 108,107,275 108,146,152 RGD:2290270
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
G Rfk riboflavin kinase JBrowse link 19 17,394,043 17,401,349 RGD:2290270
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 21,484,624 21,488,833 RGD:2290270
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:2290270
G Apoe apolipoprotein E JBrowse link 7 19,696,244 19,701,310 RGD:2290270
G Calm1 calmodulin 1 JBrowse link 12 100,199,435 100,209,824 RGD:9068941
G Calm2 calmodulin 2 JBrowse link 17 87,433,401 87,446,935 RGD:9068941
G Calm3 calmodulin 3 JBrowse link 7 16,915,379 16,924,032 RGD:9068941
G Dhfr dihydrofolate reductase JBrowse link 13 92,354,783 92,389,053 RGD:2290270
G Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:2290270
G Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide JBrowse link 8 3,680,280 3,694,174 RGD:2290270
G Gch1 GTP cyclohydrolase 1 JBrowse link 14 47,153,895 47,189,413 RGD:2290270
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B JBrowse link 1 86,097,546 86,116,231 RGD:2290270
G Kras Kirsten rat sarcoma viral oncogene homolog JBrowse link 6 145,216,699 145,250,420 RGD:2290270
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 6 54,923,942 54,972,674 RGD:2290270
G Npr3 natriuretic peptide receptor 3 JBrowse link 15 11,839,896 11,907,837 RGD:2290270
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit JBrowse link 10 52,417,547 52,440,192 RGD:2290270
G Ptk2b PTK2 protein tyrosine kinase 2 beta JBrowse link 14 66,153,257 66,281,100 RGD:2290270
G S100a1 S100 calcium binding protein A1 JBrowse link 3 90,511,034 90,514,330 RGD:2290270
G Scarb1 scavenger receptor class B, member 1 JBrowse link 5 125,277,087 125,341,094 RGD:2290270
G Terf2 telomeric repeat binding factor 2 JBrowse link 8 107,069,400 107,096,548 RGD:2290270
G Tert telomerase reverse transcriptase JBrowse link 13 73,626,911 73,649,843 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
positive regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase JBrowse link 2 31,688,244 31,807,093 RGD:2290270
G Abl2 v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) JBrowse link 1 156,558,590 156,649,619 RGD:2290270
G Atp7a ATPase, Cu++ transporting, alpha polypeptide JBrowse link X 106,027,224 106,128,161 RGD:2290270
G Ccs copper chaperone for superoxide dismutase JBrowse link 19 4,825,366 4,839,356 RGD:2290270
G Fdx1 ferredoxin 1 JBrowse link 9 51,943,023 51,963,602 RGD:2290270
G Lgals9 lectin, galactose binding, soluble 9 JBrowse link 11 78,962,979 78,984,924 RGD:2290270
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 8 88,647,315 88,688,474 RGD:2290270
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 14 55,784,995 55,788,857 RGD:2290270
positive regulation of prostaglandin-endoperoxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Edn1 endothelin 1 JBrowse link 13 42,301,476 42,307,990 RGD:2290270
G Edn2 endothelin 2 JBrowse link 4 120,161,206 120,167,360 RGD:2290270
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 8 88,647,315 88,688,474 RGD:2290270
positive regulation of pyrroline-5-carboxylate reductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
positive regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 JBrowse link 4 11,958,183 11,966,450 RGD:2290270
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 JBrowse link 8 104,591,472 104,599,026 RGD:2290270
positive regulation of succinate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ftmt ferritin mitochondrial JBrowse link 18 52,331,536 52,332,996 RGD:2290270
G Fxn frataxin JBrowse link 19 24,259,545 24,280,590 RGD:2290270
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase, Cu++ transporting, alpha polypeptide JBrowse link X 106,027,224 106,128,161 RGD:2290270
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
G Rgn regucalcin JBrowse link X 20,549,766 20,562,089 RGD:2290270
G Sirt3 sirtuin 3 JBrowse link 7 140,863,663 140,882,309 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
positive regulation of tyrosine 3-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
positive regulation of vitamin D 24-hydroxylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 10 127,048,246 127,054,884 RGD:2290270
G Fgf23 fibroblast growth factor 23 JBrowse link 6 127,072,902 127,082,296 RGD:2290270
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor JBrowse link 15 97,854,427 97,908,296 RGD:2290270
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor JBrowse link 15 97,854,427 97,908,296 RGD:2290270
regulation of cytochrome-c oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase, Cu++ transporting, alpha polypeptide JBrowse link X 106,027,224 106,128,161 RGD:2290270
G Phb2 prohibitin 2 JBrowse link 6 124,712,289 124,716,945 RGD:2290270
G Sphk2 sphingosine kinase 2 JBrowse link 7 45,709,463 45,718,002 RGD:2290270
G Taco1 translational activator of mitochondrially encoded cytochrome c oxidase I JBrowse link 11 106,066,057 106,074,035 RGD:2290270
regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slamf8 SLAM family member 8 JBrowse link 1 172,581,377 172,590,873 RGD:2290270
regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr2a activin receptor IIA JBrowse link 2 48,814,109 48,903,264 RGD:2290270
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:2290270
G Il1a interleukin 1 alpha JBrowse link 2 129,299,609 129,310,186 RGD:2290270
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:2290270
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:2290270
regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt4 sirtuin 4 JBrowse link 5 115,478,006 115,490,264 RGD:2290270
regulation of succinate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt5 sirtuin 5 JBrowse link 13 43,365,389 43,395,203 RGD:2290270
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Szt2 SZT2 subunit of KICSTOR complex JBrowse link 4 118,362,740 118,409,286 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23159
    metabolic process 10977
      regulation of metabolic process 6629
        regulation of oxidoreductase activity 98
          negative regulation of oxidoreductase activity + 34
          positive regulation of oxidoreductase activity + 54
          regulation of D-amino-acid oxidase activity + 0
          regulation of NAD(P)H oxidase activity + 9
          regulation of cytokinin dehydrogenase activity + 0
          regulation of electron transfer activity + 8
          regulation of heme oxygenase activity + 0
          regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity + 0
          regulation of malate dehydrogenase (decarboxylating) (NADP+) activity + 0
          regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity + 0
          regulation of monooxygenase activity + 47
          regulation of peroxidase activity + 4
          regulation of prostaglandin-endoperoxide synthase activity + 3
          regulation of pyrroline-5-carboxylate reductase activity + 1
          regulation of pyruvate dehydrogenase activity + 8
          regulation of ribonucleoside-diphosphate reductase activity + 0
          regulation of succinate dehydrogenase activity + 3
          regulation of superoxide dismutase activity + 6
Path 2
Term Annotations click to browse term
  biological_process 23159
    biological regulation 12767
      regulation of biological process 12158
        regulation of metabolic process 6629
          regulation of oxidoreductase activity 98
            negative regulation of oxidoreductase activity + 34
            positive regulation of oxidoreductase activity + 54
            regulation of D-amino-acid oxidase activity + 0
            regulation of NAD(P)H oxidase activity + 9
            regulation of cytokinin dehydrogenase activity + 0
            regulation of electron transfer activity + 8
            regulation of heme oxygenase activity + 0
            regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity + 0
            regulation of malate dehydrogenase (decarboxylating) (NADP+) activity + 0
            regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity + 0
            regulation of monooxygenase activity + 47
            regulation of peroxidase activity + 4
            regulation of prostaglandin-endoperoxide synthase activity + 3
            regulation of pyrroline-5-carboxylate reductase activity + 1
            regulation of pyruvate dehydrogenase activity + 8
            regulation of ribonucleoside-diphosphate reductase activity + 0
            regulation of succinate dehydrogenase activity + 3
            regulation of superoxide dismutase activity + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.