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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of oxidoreductase activity
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Accession:GO:0051341 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Synonyms:exact_synonym: oxidoreductase regulator


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regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ECSIT ECSIT signaling integrator JBrowse link 19 11,505,916 11,529,134 RGD:2290271
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 JBrowse link 12 57,762,334 57,767,078 RGD:2290271
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 1 92,473,043 92,486,925 RGD:2290271
G NFKB1 nuclear factor kappa B subunit 1 JBrowse link 4 102,501,266 102,617,302 RGD:2290271
negative regulation of D-amino-acid oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DAOA D-amino acid oxidase activator JBrowse link 13 105,465,867 105,491,034 RGD:2290271
negative regulation of electron transfer activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase JBrowse link 12 31,647,160 31,673,114 RGD:2290271
negative regulation of monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 4 89,724,099 89,838,324 RGD:2290271
negative regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DRD5 dopamine receptor D5 JBrowse link 4 9,781,634 9,784,009 RGD:2290271
G IL13 interleukin 13 JBrowse link 5 132,656,522 132,661,110 RGD:2290271
G INS insulin JBrowse link 11 2,159,779 2,161,209 RGD:2290271
negative regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG2 arginase 2 JBrowse link 14 67,619,920 67,651,708 RGD:9068941
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 1 203,626,787 203,744,081 RGD:2290271
G CAV1 caveolin 1 JBrowse link 7 116,525,009 116,561,185 RGD:2290271
G CAV3 caveolin 3 JBrowse link 3 8,733,802 8,746,758 RGD:2290271
G CNR1 cannabinoid receptor 1 JBrowse link 6 88,139,864 88,167,349 RGD:2290271
G CNR2 cannabinoid receptor 2 JBrowse link 1 23,870,515 23,913,362 RGD:2290271
G ENG endoglin JBrowse link 9 127,815,012 127,854,773 RGD:2290271
G GLA galactosidase alpha JBrowse link X 101,397,803 101,407,925 RGD:2290271
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:9068941
G NOSIP nitric oxide synthase interacting protein JBrowse link 19 49,555,468 49,580,572 RGD:2290271
negative regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GZMA granzyme A JBrowse link 5 55,102,646 55,110,252 RGD:2290271
G HDAC6 histone deacetylase 6 JBrowse link X 48,801,398 48,824,982 RGD:2290271
G HP haptoglobin JBrowse link 16 72,054,505 72,061,056 RGD:2290271
G MT3 metallothionein 3 JBrowse link 16 56,589,528 56,591,085 RGD:2290271
G OXA1L OXA1L mitochondrial inner membrane protein JBrowse link 14 22,766,688 22,773,042 RGD:2290271
G PRDX5 peroxiredoxin 5 JBrowse link 11 64,318,121 64,321,811 RGD:2290271
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) JBrowse link 17 44,248,390 44,268,161 RGD:2290271
G TMLHE trimethyllysine hydroxylase, epsilon JBrowse link X 155,489,011 155,612,952 RGD:2290271
negative regulation of peroxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 67,583,812 67,586,653 RGD:9068941
negative regulation of primary amine oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AOC3 amine oxidase copper containing 3 JBrowse link 17 42,851,182 42,858,130 RGD:2290271
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 161,347,417 162,727,802 RGD:2290271
negative regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCKDK branched chain keto acid dehydrogenase kinase JBrowse link 16 31,108,381 31,117,651 RGD:2290271
G PDK1 pyruvate dehydrogenase kinase 1 JBrowse link 2 172,555,373 172,672,698 RGD:2290271
G PDK2 pyruvate dehydrogenase kinase 2 JBrowse link 17 50,094,737 50,112,152 RGD:2290271
G PDK3 pyruvate dehydrogenase kinase 3 JBrowse link X 24,465,286 24,550,466 RGD:2290271
G PDK4 pyruvate dehydrogenase kinase 4 JBrowse link 7 95,583,499 95,596,516 RGD:2290271
negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LRRK2 leucine rich repeat kinase 2 JBrowse link 12 40,224,890 40,369,285 RGD:2290271
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:2290271
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:2290271
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:2290271
positive regulation of catalase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT3 sirtuin 3 JBrowse link 11 215,030 236,931 RGD:2290271
positive regulation of cytochrome-c oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 10 45,374,166 45,446,121 RGD:9068941
G ATP7A ATPase copper transporting alpha JBrowse link X 77,910,656 78,050,395 RGD:9068941
G COA8 cytochrome c oxidase assembly factor 8 JBrowse link 14 103,562,960 103,590,899 RGD:2290271
G COX17 cytochrome c oxidase copper chaperone COX17 JBrowse link 3 119,663,975 119,677,406 RGD:2290271
positive regulation of glutathione peroxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 4 89,724,099 89,838,324 RGD:2290271
positive regulation of monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GDNF glial cell derived neurotrophic factor JBrowse link 5 37,812,677 37,840,044 RGD:2290271
G POR cytochrome p450 oxidoreductase JBrowse link 7 75,915,155 75,986,855 RGD:2290271
positive regulation of monophenol monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDH3 cadherin 3 JBrowse link 16 68,644,914 68,727,573 RGD:2290271
positive regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGT angiotensinogen JBrowse link 1 230,702,523 230,745,583 RGD:2290271
G AGTR1 angiotensin II receptor type 1 JBrowse link 3 148,697,871 148,743,003 RGD:2290271
G CYBA cytochrome b-245 alpha chain JBrowse link 16 88,643,289 88,651,079 RGD:2290271
G GNAI2 G protein subunit alpha i2 JBrowse link 3 50,227,068 50,259,362 RGD:2290271
G GNAI3 G protein subunit alpha i3 JBrowse link 1 109,548,615 109,600,195 RGD:2290271
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,961,654 7,985,505 RGD:2290271
G RFK riboflavin kinase JBrowse link 9 76,385,526 76,394,426 RGD:2290271
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGTR2 angiotensin II receptor type 2 JBrowse link X 116,170,744 116,174,974 RGD:2290271
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:2290271
G APOE apolipoprotein E JBrowse link 19 44,905,796 44,909,395 RGD:2290271
G CALM1 calmodulin 1 JBrowse link 14 90,396,502 90,408,275 RGD:2290271
G CALM2 calmodulin 2 JBrowse link 2 47,160,082 47,176,936 RGD:2290271
G CALM3 calmodulin 3 JBrowse link 19 46,601,074 46,610,782 RGD:2290271
G DHFR dihydrofolate reductase JBrowse link 5 80,626,226 80,654,983 RGD:2290271
G DHFRP1 dihydrofolate reductase pseudogene 1 JBrowse link 18 26,167,862 26,171,357 RGD:2290271
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:2290271
G FCER2 Fc fragment of IgE receptor II JBrowse link 19 7,688,757 7,702,755 RGD:2290271
G GCH1 GTP cyclohydrolase 1 JBrowse link 14 54,842,005 54,902,826 RGD:2290271
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:2290271
G HTR2B 5-hydroxytryptamine receptor 2B JBrowse link 2 231,108,230 231,126,172 RGD:2290271
G INS insulin JBrowse link 11 2,159,779 2,161,209 RGD:2290271
G KRAS KRAS proto-oncogene, GTPase JBrowse link 12 25,205,246 25,250,929 RGD:2290271
G NOD1 nucleotide binding oligomerization domain containing 1 JBrowse link 7 30,424,527 30,478,866 RGD:2290271
G NOS1AP nitric oxide synthase 1 adaptor protein JBrowse link 1 162,069,691 162,370,475 RGD:2290271
G NPR3 natriuretic peptide receptor 3 JBrowse link 5 32,689,076 32,791,724 RGD:2290271
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit JBrowse link 6 117,675,469 117,710,727 RGD:2290271
G PTK2B protein tyrosine kinase 2 beta JBrowse link 8 27,311,478 27,459,391 RGD:2290271
G S100A1 S100 calcium binding protein A1 JBrowse link 1 153,628,434 153,632,039 RGD:2290271
G SCARB1 scavenger receptor class B member 1 JBrowse link 12 124,776,856 124,863,864 RGD:2290271
G TERF2 telomeric repeat binding factor 2 JBrowse link 16 69,355,567 69,386,007 RGD:2290271
G TERT telomerase reverse transcriptase JBrowse link 5 1,253,148 1,295,068 RGD:2290271
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:2290271
positive regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,713,881 130,887,675 RGD:2290271
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 1 179,099,330 179,229,693 RGD:2290271
G ATP7A ATPase copper transporting alpha JBrowse link X 77,910,656 78,050,395 RGD:2290271
G CCS copper chaperone for superoxide dismutase JBrowse link 11 66,593,162 66,606,019 RGD:2290271
G FDX1 ferredoxin 1 JBrowse link 11 110,429,948 110,464,884 RGD:9068941
G LGALS9 galectin 9 JBrowse link 17 27,631,172 27,649,560 RGD:9068941
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 16 50,693,587 50,733,077 RGD:2290271
G RIPK3 receptor interacting serine/threonine kinase 3 JBrowse link 14 24,336,025 24,339,991 RGD:2290271
positive regulation of prostaglandin-endoperoxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EDN1 endothelin 1 JBrowse link 6 12,256,463 12,297,194 RGD:2290271
G EDN2 endothelin 2 JBrowse link 1 41,478,775 41,484,699 RGD:2290271
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 16 50,693,587 50,733,077 RGD:2290271
positive regulation of pyrroline-5-carboxylate reductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,961,654 7,985,505 RGD:2290271
positive regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 JBrowse link 8 93,916,923 93,926,068 RGD:2290271
G PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 JBrowse link 16 66,880,515 66,891,101 RGD:2290271
positive regulation of succinate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FTMT ferritin mitochondrial JBrowse link 5 121,851,882 121,852,833 RGD:2290271
G FXN frataxin JBrowse link 9 69,035,752 69,079,076 RGD:2290271
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 77,910,656 78,050,395 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,961,654 7,985,505 RGD:2290271
G RGN regucalcin JBrowse link X 47,078,355 47,093,314 RGD:2290271
G SIRT3 sirtuin 3 JBrowse link 11 215,030 236,931 RGD:2290271
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:2290271
positive regulation of tyrosine 3-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 1 7,961,654 7,985,505 RGD:2290271
positive regulation of vitamin D 24-hydroxylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 JBrowse link 12 57,762,334 57,767,078 RGD:2290271
G FGF23 fibroblast growth factor 23 JBrowse link 12 4,368,227 4,379,712 RGD:2290271
G VDR vitamin D receptor JBrowse link 12 47,841,537 47,905,022 RGD:2290271
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VDR vitamin D receptor JBrowse link 12 47,841,537 47,905,022 RGD:2290271
regulation of cytochrome-c oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 77,910,656 78,050,395 RGD:2290271
G PHB2 prohibitin 2 JBrowse link 12 6,965,327 6,970,753 RGD:2290271
G SPHK2 sphingosine kinase 2 JBrowse link 19 48,619,291 48,630,407 RGD:2290271
G TACO1 translational activator of cytochrome c oxidase I JBrowse link 17 63,600,895 63,608,365 RGD:2290271
regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLAMF8 SLAM family member 8 JBrowse link 1 159,826,689 159,837,497 RGD:2290271
regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACVR2A activin A receptor type 2A JBrowse link 2 147,844,517 147,930,827 RGD:2290271
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:2290271
G CALM1 calmodulin 1 JBrowse link 14 90,396,502 90,408,275 RGD:2290271
G CALM2 calmodulin 2 JBrowse link 2 47,160,082 47,176,936 RGD:2290271
G CALM3 calmodulin 3 JBrowse link 19 46,601,074 46,610,782 RGD:2290271
G CAV1 caveolin 1 JBrowse link 7 116,525,009 116,561,185 RGD:2290271
G CYGB cytoglobin JBrowse link 17 76,527,356 76,557,692 RGD:2290271
G DDAH1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 1 85,318,485 85,578,274 RGD:2290271
G DDAH2 dimethylarginine dimethylaminohydrolase 2 JBrowse link 6 31,727,040 31,730,263 RGD:2290271
G DNM2 dynamin 2 JBrowse link 19 10,718,053 10,831,910 RGD:2290271
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:2290271
G HSP90AA1 heat shock protein 90 alpha family class A member 1 JBrowse link 14 102,080,742 102,139,749 RGD:2290271
G IL1A interleukin 1 alpha JBrowse link 2 112,773,925 112,784,493 RGD:2290271
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:2290271
G LEP leptin JBrowse link 7 128,241,201 128,257,629 RGD:2290271
G LYPLA1 lysophospholipase 1 JBrowse link 8 54,046,367 54,102,017 RGD:2290271
G NOS1AP nitric oxide synthase 1 adaptor protein JBrowse link 1 162,069,691 162,370,475 RGD:2290271
G NOS3 nitric oxide synthase 3 JBrowse link 7 150,991,017 151,014,588 RGD:2290271
G NOSIP nitric oxide synthase interacting protein JBrowse link 19 49,555,468 49,580,572 RGD:2290271
G NOSTRIN nitric oxide synthase trafficking JBrowse link 2 168,786,539 168,865,514 RGD:2290271
G SPR sepiapterin reductase JBrowse link 2 72,887,408 72,892,158 RGD:2290271
G WASL WASP like actin nucleation promoting factor JBrowse link 7 123,681,943 123,749,003 RGD:2290271
G ZDHHC21 zinc finger DHHC-type palmitoyltransferase 21 JBrowse link 9 14,588,797 14,693,432 RGD:2290271
regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT4 sirtuin 4 JBrowse link 12 120,290,639 120,313,242 RGD:2290271
regulation of succinate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT5 sirtuin 5 JBrowse link 6 13,574,217 13,615,158 RGD:2290271
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 1 43,389,884 43,454,247 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18536
    metabolic process 12194
      regulation of metabolic process 7482
        regulation of oxidoreductase activity 116
          negative regulation of oxidoreductase activity + 36
          positive regulation of oxidoreductase activity + 60
          regulation of D-amino-acid oxidase activity + 1
          regulation of NAD(P)H oxidase activity + 11
          regulation of cytokinin dehydrogenase activity + 0
          regulation of electron transfer activity + 8
          regulation of heme oxygenase activity + 0
          regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity + 0
          regulation of malate dehydrogenase (decarboxylating) (NADP+) activity + 0
          regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity + 0
          regulation of monooxygenase activity + 62
          regulation of peroxidase activity + 4
          regulation of prostaglandin-endoperoxide synthase activity + 3
          regulation of pyrroline-5-carboxylate reductase activity + 1
          regulation of pyruvate dehydrogenase activity + 8
          regulation of ribonucleoside-diphosphate reductase activity + 0
          regulation of succinate dehydrogenase activity + 3
          regulation of superoxide dismutase activity + 6
Path 2
Term Annotations click to browse term
  biological_process 18536
    biological regulation 13170
      regulation of biological process 12526
        regulation of metabolic process 7482
          regulation of oxidoreductase activity 116
            negative regulation of oxidoreductase activity + 36
            positive regulation of oxidoreductase activity + 60
            regulation of D-amino-acid oxidase activity + 1
            regulation of NAD(P)H oxidase activity + 11
            regulation of cytokinin dehydrogenase activity + 0
            regulation of electron transfer activity + 8
            regulation of heme oxygenase activity + 0
            regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity + 0
            regulation of malate dehydrogenase (decarboxylating) (NADP+) activity + 0
            regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity + 0
            regulation of monooxygenase activity + 62
            regulation of peroxidase activity + 4
            regulation of prostaglandin-endoperoxide synthase activity + 3
            regulation of pyrroline-5-carboxylate reductase activity + 1
            regulation of pyruvate dehydrogenase activity + 8
            regulation of ribonucleoside-diphosphate reductase activity + 0
            regulation of succinate dehydrogenase activity + 3
            regulation of superoxide dismutase activity + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.