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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of oxidoreductase activity
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Accession:GO:0051341 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Synonyms:exact_synonym: oxidoreductase regulator


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regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ECSIT ECSIT signaling integrator JBrowse link 20 49,848,848 49,867,075 RGD:13508589
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 JBrowse link 10 1,825,224 1,830,845 RGD:13508589
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 6 56,473,032 56,484,422 RGD:13508589
G NFKB1 nuclear factor kappa B subunit 1 JBrowse link 32 23,948,598 24,040,704 RGD:9068941
negative regulation of electron transfer activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase JBrowse link 27 17,103,168 17,110,405 RGD:13508589
negative regulation of monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 32 12,915,871 13,079,338 RGD:9068941
negative regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DRD5 dopamine receptor D5 JBrowse link 3 69,621,187 69,623,522 RGD:9068941
G IL13 interleukin 13 JBrowse link 11 20,957,870 20,961,391 RGD:9068941
G INS insulin JBrowse link 18 46,324,047 46,324,933 RGD:9068941
negative regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG2 arginase 2 JBrowse link 8 41,588,051 41,619,406 RGD:9068941
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 38 321,246 420,262 RGD:13508589
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:13508589
G CAV3 caveolin 3 JBrowse link 20 9,384,901 9,398,055 RGD:13508589
G CNR1 cannabinoid receptor 1 JBrowse link 12 47,537,240 47,560,723 RGD:9068941
G CNR2 cannabinoid receptor 2 JBrowse link 2 75,640,636 75,662,000 RGD:9068941
G ENG endoglin JBrowse link 9 55,558,246 55,590,081 RGD:9068941
G GLA galactosidase alpha JBrowse link X 75,311,536 75,320,391 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 33 23,458,369 23,659,878 RGD:9068941
G NOSIP nitric oxide synthase interacting protein JBrowse link 1 106,938,223 106,958,815 RGD:9068941
negative regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GZMA granzyme A JBrowse link 2 42,490,712 42,498,655 RGD:13508589
G LOC479668 haptoglobin-like JBrowse link 5 77,795,183 77,800,034 RGD:9068941
G MT3 metallothionein 3 RGD:13508589
G OXA1L OXA1L mitochondrial inner membrane protein JBrowse link 8 3,108,669 3,132,337 RGD:9068941
G PRDX5 peroxiredoxin 5 JBrowse link 18 52,750,977 52,754,432 RGD:9068941
G SLC4A1 solute carrier family 4 member 1 JBrowse link 9 19,142,884 19,159,449 RGD:13508589
G TMLHE trimethyllysine hydroxylase, epsilon JBrowse link X 123,322,773 123,438,999 RGD:9068941
negative regulation of peroxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
negative regulation of primary amine oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AOC3 amine oxidase copper containing 3 JBrowse link 9 20,158,581 20,179,773 RGD:13508589
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 49,886,887 51,201,930 RGD:9068941
negative regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCKDK branched chain keto acid dehydrogenase kinase JBrowse link 6 17,128,615 17,132,925 RGD:13508589
G PDK1 pyruvate dehydrogenase kinase 1 JBrowse link 36 16,918,329 16,944,532 RGD:13508589
G PDK2 pyruvate dehydrogenase kinase 2 JBrowse link 9 26,099,457 26,116,094 RGD:13508589
G PDK3 pyruvate dehydrogenase kinase 3 JBrowse link X 19,994,383 20,058,979 RGD:13508589
G PDK4 pyruvate dehydrogenase kinase 4 JBrowse link 14 20,825,861 20,839,290 RGD:13508589
negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LRRK2 leucine rich repeat kinase 2 JBrowse link 27 13,282,824 13,420,917 RGD:13508589
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNG interferon gamma JBrowse link 10 10,406,866 10,411,698 RGD:13508589
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:13508589
positive regulation of catalase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT3 sirtuin 3 JBrowse link 18 25,369,183 25,388,126 RGD:13508589
positive regulation of cytochrome-c oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 28 2,170,920 2,218,765 RGD:9068941
G ATP7A ATPase copper transporting alpha JBrowse link X 60,203,336 60,356,525 RGD:9068941
G COA8 cytochrome c oxidase assembly factor 8 JBrowse link 8 71,324,271 71,357,468 RGD:13508589
G COX17 cytochrome c oxidase copper chaperone COX17 JBrowse link 33 23,305,119 23,313,022 RGD:13508589
positive regulation of glutathione peroxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 32 12,915,871 13,079,338 RGD:9068941
positive regulation of monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GDNF glial cell derived neurotrophic factor JBrowse link 4 70,966,694 70,991,860 RGD:13508589
G POR cytochrome p450 oxidoreductase JBrowse link 6 7,247,780 7,316,282 RGD:9068941
positive regulation of monophenol monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDH3 cadherin 3 JBrowse link 5 80,864,859 80,912,136 RGD:13508589
positive regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYBA cytochrome b-245 alpha chain JBrowse link 5 64,692,865 64,701,056 RGD:9068941
G GNAI2 G protein subunit alpha i2 JBrowse link 20 39,075,085 39,094,697 RGD:9068941
G GNAI3 G protein subunit alpha i3 JBrowse link 6 42,275,060 42,315,545 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
G RFK riboflavin kinase JBrowse link 1 82,062,290 82,071,033 RGD:9068941
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGTR2 angiotensin II receptor type 2 JBrowse link X 88,703,551 88,708,451 RGD:13508589
G AKT1 AKT serine/threonine kinase 1 JBrowse link 8 72,317,399 72,335,686 RGD:13508589
G APOE apolipoprotein E JBrowse link 1 110,525,717 110,528,534 RGD:13508589
G CALM1 calmodulin 1 JBrowse link 8 61,398,231 61,408,874 RGD:9068941
G CALM2 calmodulin 2 JBrowse link 10 49,299,698 49,314,533 RGD:9068941
G CALM3 calmodulin 3 JBrowse link 1 109,284,729 109,294,491 RGD:9068941
G ESR1 estrogen receptor 1 JBrowse link 1 42,081,952 42,368,544 RGD:9068941
G FCER2 Fc fragment of IgE receptor II JBrowse link 20 52,451,637 52,460,045 RGD:9068941
G GCH1 GTP cyclohydrolase 1 JBrowse link 8 30,733,422 30,784,067 RGD:13508589
G HTR2B 5-hydroxytryptamine receptor 2B JBrowse link 25 43,042,306 43,056,361 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 27 22,261,753 22,296,704 RGD:9068941
G NOD1 nucleotide binding oligomerization domain containing 1 JBrowse link 14 43,162,671 43,226,948 RGD:9068941
G NPR3 natriuretic peptide receptor 3 JBrowse link 4 74,794,553 74,863,344 RGD:9068941
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit JBrowse link 1 57,866,760 57,895,505 RGD:13508589
G PTK2B protein tyrosine kinase 2 beta JBrowse link 25 30,137,546 30,264,221 RGD:13508589
G S100A1 S100 calcium binding protein A1 JBrowse link 7 43,428,819 43,432,637 RGD:9068941
G SCARB1 scavenger receptor class B member 1 JBrowse link 26 5,035,797 5,122,383 RGD:9068941
G TERF2 telomeric repeat binding factor 2 JBrowse link 5 80,278,224 80,305,315 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 34 11,288,622 11,307,790 RGD:9068941
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:9068941
positive regulation of oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 53,118,462 53,262,092 RGD:13508589
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 7 20,696,659 20,735,362 RGD:9068941
G ATP7A ATPase copper transporting alpha JBrowse link X 60,203,336 60,356,525 RGD:13508589
G CCS copper chaperone for superoxide dismutase JBrowse link 18 50,748,039 50,759,270 RGD:13508589
G FDX1 ferredoxin 1 JBrowse link 5 22,452,011 22,485,581 RGD:9068941
G LGALS9 galectin 9 JBrowse link 9 42,154,613 42,170,423 RGD:9068941
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 2 64,636,850 64,667,232 RGD:9068941
G RIPK3 receptor interacting serine/threonine kinase 3 JBrowse link 8 4,304,167 4,309,514 RGD:9068941
positive regulation of prostaglandin-endoperoxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EDN1 endothelin 1 JBrowse link 35 11,808,892 11,815,383 RGD:13508589
G EDN2 endothelin 2 JBrowse link 15 1,647,966 1,654,272 RGD:9068941
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 2 64,636,850 64,667,232 RGD:9068941
positive regulation of pyrroline-5-carboxylate reductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
positive regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 JBrowse link 29 38,783,945 38,792,141 RGD:13508589
G PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 JBrowse link 5 82,421,531 82,428,600 RGD:13508589
positive regulation of succinate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FXN frataxin JBrowse link 1 88,288,566 88,311,228 RGD:13508589
G LOC481426 ferritin heavy chain-like JBrowse link 11 8,955,374 8,956,762 RGD:9068941
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 60,203,336 60,356,525 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
G RGN regucalcin JBrowse link X 40,697,292 40,715,491 RGD:9068941
G SIRT3 sirtuin 3 JBrowse link 18 25,369,183 25,388,126 RGD:13508589
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:13508589
positive regulation of tyrosine 3-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
positive regulation of vitamin D 24-hydroxylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 JBrowse link 10 1,825,224 1,830,845 RGD:13508589
G FGF23 fibroblast growth factor 23 JBrowse link 27 40,501,655 40,511,785 RGD:13508589
G VDR vitamin D receptor JBrowse link 27 6,852,915 6,909,466 RGD:13508589
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VDR vitamin D receptor JBrowse link 27 6,852,915 6,909,466 RGD:13508589
regulation of cytochrome-c oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 60,203,336 60,356,525 RGD:9068941
G PHB2 prohibitin 2 JBrowse link 27 38,075,769 38,080,440 RGD:9068941
G SPHK2 sphingosine kinase 2 JBrowse link 1 107,681,425 107,689,790 RGD:13508589
G TACO1 translational activator of cytochrome c oxidase I JBrowse link 9 11,598,207 11,603,357 RGD:13508589
regulation of NAD(P)H oxidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLAMF8 SLAM family member 8 JBrowse link 38 22,299,455 22,307,090 RGD:9068941
regulation of nitric-oxide synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACVR2A activin A receptor type 2A JBrowse link 19 49,642,429 49,726,720 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 18 5,983,669 6,044,092 RGD:13508589
G IL1A interleukin 1 alpha JBrowse link 17 36,969,581 36,979,445 RGD:13508589
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:13508589
G LEP leptin JBrowse link 14 8,115,396 8,130,946 RGD:13508589
regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT4 sirtuin 4 JBrowse link 26 16,228,831 16,244,104 RGD:9068941
regulation of succinate dehydrogenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIRT5 sirtuin 5 JBrowse link 35 13,017,397 13,055,655 RGD:9068941
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 15 16,729,068 16,780,549 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16043
    metabolic process 10497
      regulation of metabolic process 6327
        regulation of oxidoreductase activity 97
          negative regulation of oxidoreductase activity + 34
          positive regulation of oxidoreductase activity + 53
          regulation of D-amino-acid oxidase activity + 0
          regulation of NAD(P)H oxidase activity + 9
          regulation of cytokinin dehydrogenase activity + 0
          regulation of electron transfer activity + 8
          regulation of heme oxygenase activity + 0
          regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity + 0
          regulation of malate dehydrogenase (decarboxylating) (NADP+) activity + 0
          regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity + 0
          regulation of monooxygenase activity + 46
          regulation of peroxidase activity + 4
          regulation of prostaglandin-endoperoxide synthase activity + 3
          regulation of pyrroline-5-carboxylate reductase activity + 1
          regulation of pyruvate dehydrogenase activity + 8
          regulation of ribonucleoside-diphosphate reductase activity + 0
          regulation of succinate dehydrogenase activity + 3
          regulation of superoxide dismutase activity + 6
Path 2
Term Annotations click to browse term
  biological_process 16043
    biological regulation 11410
      regulation of biological process 10828
        regulation of metabolic process 6327
          regulation of oxidoreductase activity 97
            negative regulation of oxidoreductase activity + 34
            positive regulation of oxidoreductase activity + 53
            regulation of D-amino-acid oxidase activity + 0
            regulation of NAD(P)H oxidase activity + 9
            regulation of cytokinin dehydrogenase activity + 0
            regulation of electron transfer activity + 8
            regulation of heme oxygenase activity + 0
            regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity + 0
            regulation of malate dehydrogenase (decarboxylating) (NADP+) activity + 0
            regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity + 0
            regulation of monooxygenase activity + 46
            regulation of peroxidase activity + 4
            regulation of prostaglandin-endoperoxide synthase activity + 3
            regulation of pyrroline-5-carboxylate reductase activity + 1
            regulation of pyruvate dehydrogenase activity + 8
            regulation of ribonucleoside-diphosphate reductase activity + 0
            regulation of succinate dehydrogenase activity + 3
            regulation of superoxide dismutase activity + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.