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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ligase activity
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Accession:GO:0051340 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
Synonyms:exact_synonym: ligase regulator



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negative regulation of leucine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgn regucalcin IDA RGD PMID:2280766 RGD:9590217 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
positive regulation of glutamate-cysteine ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclm glutamate cysteine ligase, modifier subunit IDA RGD PMID:16137247 RGD:1582663 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
positive regulation of isoleucine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl5 ribosomal protein L5 IMP RGD PMID:1665486 RGD:11040680 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
positive regulation of methionine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl5 ribosomal protein L5 IMP RGD PMID:1665486 RGD:11040680 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
positive regulation of threonine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl5 ribosomal protein L5 IMP RGD PMID:8049265 RGD:1556518 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of molecular function 323
        regulation of catalytic activity 195
          regulation of ligase activity 3
            negative regulation of ligase activity + 1
            positive regulation of ligase activity + 2
            regulation of DNA ligase activity + 0
            regulation of aminoacyl-tRNA ligase activity + 2
            regulation of glutamate-cysteine ligase activity + 1
            regulation of proton-transporting ATP synthase activity, rotational mechanism + 0
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