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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lyase activity
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Accession:GO:0051339 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
Synonyms:exact_synonym: lyase regulator


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activation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACR acrosin involved_in IDA (PMID:3880736) UniProt
UniProt		 PMID:3880736 NCBI chr22:50,738,204...50,745,339
Ensembl chr22:50,738,196...50,745,339 		JBrowse link
G ADCY3 adenylate cyclase 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr 2:24,819,169...24,920,237
Ensembl chr 2:24,819,169...24,920,237 		JBrowse link
G ADCY5 adenylate cyclase 5 involved_in IEA UniProt GO_REF:0000117 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090 		JBrowse link
G ADCY8 adenylate cyclase 8 involved_in IEA UniProt GO_REF:0000117 NCBI chr 8:130,780,301...131,040,909
Ensembl chr 8:130,780,301...131,040,909 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 involved_in TAS (PMID:1730060) PINC
PINC		 PMID:1730060 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G ADORA2B adenosine A2b receptor involved_in TAS (PMID:8022409) PINC
PINC		 PMID:8022409 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746 		JBrowse link
G ADORA3 adenosine A3 receptor involved_in TAS (PMID:9380026) PINC
PINC		 PMID:9380026 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633 		JBrowse link
G ADRB1 adrenoceptor beta 1 involved_in TAS (PMID:10212248) PINC
PINC		 PMID:10212248 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in IDA (PMID:15123695) HGNC-UCL
HGNC-UCL		 PMID:15123695 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ADRB3 adrenoceptor beta 3 involved_in IDA (PMID:15123695) HGNC-UCL
HGNC-UCL		 PMID:15123695 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
G AVPR2 arginine vasopressin receptor 2 involved_in TAS (PMID:9224808) PINC
PINC		 PMID:9224808 NCBI chr  X:153,902,625...153,907,166
Ensembl chr  X:153,902,531...153,907,166 		JBrowse link
G CALCA calcitonin related polypeptide alpha involved_in
acts_upstream_of_or_within		 IEA
IDA
ISO		 (PMID:10822112), (PMID:16014619)
(MGI:77881|PMID:8582325)		 Ensembl
Ensembl
UniProt
MGI
UniProt		 PMID:8582325 PMID:10822112 PMID:16014619 GO_REF:0000107 MGI:77881 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CALCR calcitonin receptor NOT|involved_in IDA (PMID:15563840) UniProt
UniProt		 PMID:15563840 NCBI chr 7:93,424,486...93,574,724
Ensembl chr 7:93,424,486...93,574,730 		JBrowse link
G CALM1 calmodulin 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268 		JBrowse link
G CALM2 calmodulin 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,084...47,176,921 		JBrowse link
G CALM3 calmodulin 3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782 		JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 involved_in TAS (PMID:7962207) PINC
PINC		 PMID:7962207 NCBI chr 1:40,040,240...40,072,648
Ensembl chr 1:40,040,233...40,072,649 		JBrowse link
G CAP2 cyclase associated actin cytoskeleton regulatory protein 2 involved_in TAS (PMID:7962207) PINC
PINC		 PMID:7962207 NCBI chr 6:17,393,595...17,557,780
Ensembl chr 6:17,393,595...17,557,780 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in TAS (PMID:10598591) PINC
PINC		 PMID:10598591 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G DRD1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 (PMID:2168520)
(MGI:2450485|PMID:12488442)		 BHF-UCL
BHF-UCL
Ensembl
MGI		 PMID:2168520 PMID:12488442 GO_REF:0000107 MGI:2450485 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD5 dopamine receptor D5 involved_in TAS (PMID:9457173) BHF-UCL
BHF-UCL		 PMID:9457173 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G EDNRA endothelin receptor type A involved_in TAS (PMID:8702836) PINC
PINC		 PMID:8702836 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G FSHR follicle stimulating hormone receptor involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527 		JBrowse link
G GHRHR growth hormone releasing hormone receptor involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:9845677 GO_REF:0000107 RGD:1601338 NCBI chr 7:30,963,953...30,979,528
Ensembl chr 7:30,938,669...30,993,254 		JBrowse link
G GIPR gastric inhibitory polypeptide receptor involved_in TAS (PMID:7589426) PINC
PINC		 PMID:7589426 NCBI chr19:45,668,221...45,683,722
Ensembl chr19:45,668,221...45,683,722 		JBrowse link
G GLP1R glucagon like peptide 1 receptor involved_in TAS (PMID:8405712) PINC
PINC		 PMID:8405712 NCBI chr 6:39,048,781...39,091,303
Ensembl chr 6:39,048,781...39,091,303 		JBrowse link
G GNAL G protein subunit alpha L acts_upstream_of_or_within ISO (MGI:2450485|PMID:12488442) MGI PMID:12488442 MGI:2450485 NCBI chr18:11,689,264...11,885,685
Ensembl chr18:11,689,264...11,885,685 		JBrowse link
G GNAS GNAS complex locus involved_in TAS (PMID:9159128) UniProt
UniProt		 PMID:9159128 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:27,365,961...27,472,790
Ensembl chr11:27,365,961...27,472,790 		JBrowse link
G LGR5 leucine rich repeat containing G protein-coupled receptor 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:71,439,129...71,586,310
Ensembl chr12:71,439,798...71,586,310 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor involved_in ISS
IEA
IBA
ISO		 (PMID:21873635) BHF-UCL
Ensembl
GO_Central
BHF-UCL
RGD
GO_Central		 PMID:8440169 PMID:21873635 GO_REF:0000024 GO_REF:0000107 RGD:2292602 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730 		JBrowse link
G LINC02210-CRHR1 LINC02210-CRHR1 readthrough involved_in TAS (PMID:10598591) PINC
PINC		 PMID:10598591 NCBI chr17:45,620,346...45,835,828
Ensembl chr17:45,620,344...45,835,826
Ensembl chr17:45,620,344...45,835,826 		JBrowse link
G P2RY11 purinergic receptor P2Y11 involved_in TAS (PMID:9405388) PINC
PINC		 PMID:9405388 NCBI chr19:10,111,693...10,115,372
Ensembl chr19:10,111,693...10,115,372 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in IDA (PMID:15385642) BHF-UCL
BHF-UCL		 PMID:15385642 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RXFP1 relaxin family peptide receptor 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 4:158,521,714...158,653,372
Ensembl chr 4:158,315,311...158,653,372 		JBrowse link
G RXFP2 relaxin family peptide receptor 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr13:31,739,526...31,803,389
Ensembl chr13:31,739,526...31,803,389 		JBrowse link
G TMIGD3 transmembrane and immunoglobulin domain containing 3 involved_in TAS (PMID:9380026) PINC
PINC		 PMID:9380026 NCBI chr 1:111,483,348...111,563,962
Ensembl chr 1:111,483,348...111,563,962 		JBrowse link
G TSHR thyroid stimulating hormone receptor involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr14:80,955,621...81,146,306
Ensembl chr14:80,954,989...81,146,306 		JBrowse link
G VIPR2 vasoactive intestinal peptide receptor 2 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:8224221 GO_REF:0000107 RGD:70054 NCBI chr 7:159,028,175...159,144,867
Ensembl chr 7:159,028,175...159,144,867 		JBrowse link
negative regulation of aconitate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR210 microRNA 210 involved_in IDA (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198 		JBrowse link
negative regulation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in ISS
IBA
IEA		 (PMID:21873635) UniProt
GO_Central
UniProt
InterPro
InterPro		 PMID:21873635 GO_REF:0000002 GO_REF:0000024 NCBI chr 5:90,558,797...91,164,437
Ensembl chr 5:90,529,344...91,164,437 		JBrowse link
G AKAP5 A-kinase anchoring protein 5 involved_in IMP
ISO		 (PMID:20410303), (PMID:21771783) UniProt
UniProt
RGD		 PMID:20410303 PMID:21771783 RGD:7242424 NCBI chr14:64,465,499...64,474,503
Ensembl chr14:64,465,499...64,474,503 		JBrowse link
G AKAP6 A-kinase anchoring protein 6 ISO RGD PMID:19574217 RGD:6902943 NCBI chr14:32,329,298...32,837,684
Ensembl chr14:32,329,298...32,837,684 		JBrowse link
G AKAP9 A-kinase anchoring protein 9 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:18772391 GO_REF:0000107 RGD:2313147 NCBI chr 7:91,940,862...92,110,673
Ensembl chr 7:91,940,840...92,110,673 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 involved_in TAS (PMID:8995400) PINC
PINC		 PMID:8995400 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G DRD2 dopamine receptor D2 involved_in IDA
IBA		 (PMID:2531656)
(PMID:21873635)		 BHF-UCL
GO_Central
BHF-UCL
GO_Central		 PMID:2531656 PMID:21873635 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DRD3 dopamine receptor D3 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407 		JBrowse link
G EDNRB endothelin receptor type B involved_in TAS (PMID:9556633) PINC
PINC		 PMID:9556633 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 involved_in ISO
IEA		 RGD
Ensembl
Ensembl		 PMID:15147298 GO_REF:0000107 RGD:2315493 NCBI chr 6:29,602,238...29,633,183
Ensembl chr 6:29,555,629...29,633,976 		JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 involved_in TAS (PMID:10328880) PINC
PINC		 PMID:10328880 NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935 		JBrowse link
G GALR1 galanin receptor 1 involved_in IEA
TAS		 (PMID:7524088) InterPro
PINC
InterPro		 PMID:7524088 GO_REF:0000002 NCBI chr18:77,249,848...77,277,900
Ensembl chr18:77,249,848...77,277,900 		JBrowse link
G GALR2 galanin receptor 2 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr17:76,071,962...76,077,537
Ensembl chr17:76,074,781...76,077,537 		JBrowse link
G GALR3 galanin receptor 3 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr22:37,823,382...37,825,485
Ensembl chr22:37,823,382...37,825,485 		JBrowse link
G GNAI2 G protein subunit alpha i2 involved_in TAS (PMID:9637720) PINC
PINC		 PMID:9637720 NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362 		JBrowse link
G GNAI3 G protein subunit alpha i3 involved_in TAS (PMID:7608168) PINC
PINC		 PMID:7608168 NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195 		JBrowse link
G GPR87 G protein-coupled receptor 87 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr 3:151,294,086...151,316,820
Ensembl chr 3:151,294,086...151,316,820 		JBrowse link
G GRM2 glutamate metabotropic receptor 2 involved_in TAS (PMID:7620613) PINC
PINC		 PMID:7620613 NCBI chr 3:51,707,068...51,718,613
Ensembl chr 3:51,707,068...51,718,613 		JBrowse link
G GRM3 glutamate metabotropic receptor 3 involved_in TAS (PMID:8840013) PINC
PINC		 PMID:8840013 NCBI chr 7:86,643,909...86,864,879
Ensembl chr 7:86,643,909...86,864,879 		JBrowse link
G HRH3 histamine receptor H3 ISO RGD PMID:10869375 RGD:632981 NCBI chr20:62,214,960...62,220,278
Ensembl chr20:62,214,960...62,220,278 		JBrowse link
G LTB4R2 leukotriene B4 receptor 2 involved_in TAS (PMID:10889186) PINC
PINC		 PMID:10889186 NCBI chr14:24,310,140...24,312,038
Ensembl chr14:24,305,734...24,312,053 		JBrowse link
G NPR3 natriuretic peptide receptor 3 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:8702617 GO_REF:0000107 RGD:1601497 NCBI chr 5:32,690,872...32,791,720
Ensembl chr 5:32,689,070...32,791,724 		JBrowse link
G P2RY13 purinergic receptor P2Y13 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr 3:151,326,312...151,329,549
Ensembl chr 3:151,326,312...151,329,549 		JBrowse link
G PALM paralemmin involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:3618440|PMID:16386234)		 GO_Central
Ensembl
GO_Central
MGI		 PMID:16386234 PMID:21873635 GO_REF:0000107 MGI:3618440 NCBI chr19:708,935...748,329
Ensembl chr19:708,935...748,329 		JBrowse link
negative regulation of cystathionine beta-synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IDA (PMID:24416422) BHF-UCL
BHF-UCL		 PMID:24416422 NCBI chr 5:7,850,859...7,901,113
Ensembl chr 5:7,851,186...7,906,025 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:15336960 GO_REF:0000107 RGD:9686438 NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441 		JBrowse link
G NHERF4 NHERF family PDZ scaffold protein 4 involved_in IEA GOC GO_REF:0000108 NCBI chr11:119,185,475...119,190,213
Ensembl chr11:119,185,457...119,190,223 		JBrowse link
G RD3 RD3 regulator of GUCY2D involved_in IMP
IEA		 (PMID:21928830), (PMID:30559291) UniProt
Ensembl
UniProt		 PMID:21928830 PMID:30559291 GO_REF:0000107 NCBI chr 1:211,476,522...211,492,162
Ensembl chr 1:211,476,522...211,492,162 		JBrowse link
negative regulation of lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHPT1 phosphohistidine phosphatase 1 involved_in IDA (PMID:20110805), (PMID:20501872) BHF-UCL
BHF-UCL		 PMID:20110805 PMID:20501872 NCBI chr 9:136,849,409...136,851,024
Ensembl chr 9:136,848,724...136,851,027 		JBrowse link
positive regulation of aconitate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FTMT ferritin mitochondrial involved_in IGI (PMID:18160053) BHF-UCL
BHF-UCL		 PMID:18160053 NCBI chr 5:121,851,882...121,852,833
Ensembl chr 5:121,851,882...121,852,833 		JBrowse link
G FXN frataxin involved_in IMP (PMID:18160053) BHF-UCL
BHF-UCL		 PMID:18160053 NCBI chr 9:69,035,752...69,079,076
Ensembl chr 9:69,035,751...69,079,076 		JBrowse link
G ISCU iron-sulfur cluster assembly enzyme involved_in IMP (PMID:20436681) ARUK-UCL
ARUK-UCL		 PMID:20436681 NCBI chr12:108,561,463...108,569,384
Ensembl chr12:108,562,582...108,569,368 		JBrowse link
positive regulation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:21143600 RGD:8693686 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G AKAP5 A-kinase anchoring protein 5 involved_in IBA
IEA
ISO		 (PMID:21873635) GO_Central
InterPro
GO_Central
RGD		 PMID:20410303 PMID:21873635 GO_REF:0000002 RGD:7242424 NCBI chr14:64,465,499...64,474,503
Ensembl chr14:64,465,499...64,474,503 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in ISS UniProt
UniProt		 GO_REF:0000024 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in ISS UniProt
UniProt		 GO_REF:0000024 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733 		JBrowse link
G CALCR calcitonin receptor involved_in IDA (PMID:7588285), (PMID:7769107) UniProt
UniProt		 PMID:7588285 PMID:7769107 NCBI chr 7:93,424,486...93,574,724
Ensembl chr 7:93,424,486...93,574,730 		JBrowse link
G DRD5 dopamine receptor D5 involved_in NAS (PMID:7727453) UniProt
UniProt		 PMID:7727453 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G GCG glucagon ISO RGD PMID:2235678 RGD:11556254 RGD:11556254 RGD:150520179 NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404 		JBrowse link
G HPCA hippocalcin involved_in IEA
ISO		 Ensembl
RGD
Ensembl		 PMID:15336960 GO_REF:0000107 RGD:9686438 NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (MGI:3628716|PMID:11788835) HGNC-UCL
MGI
Ensembl
HGNC-UCL		 PMID:11788835 GO_REF:0000024 GO_REF:0000107 MGI:3628716 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116 		JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 involved_in IDA (PMID:19171672) UniProt
UniProt		 PMID:19171672 NCBI chr12:121,626,550...121,642,040
Ensembl chr12:121,626,509...121,643,218 		JBrowse link
G STIM1 stromal interaction molecule 1 involved_in IDA (PMID:19171672) UniProt
UniProt		 PMID:19171672 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:15901773 RGD:1598578 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3794903|PMID:18340377) MGI
Ensembl
Ensembl		 PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746 		JBrowse link
G GUCA1A guanylate cyclase activator 1A involved_in ISS
IEA
ISO		 UniProt
Ensembl
UniProt
GOC
RGD		 PMID:12545196 GO_REF:0000024 GO_REF:0000107 GO_REF:0000108 RGD:1599357 NCBI chr 6:42,173,364...42,180,056
Ensembl chr 6:42,173,364...42,181,338 		JBrowse link
G GUCA1ANB GUCA1A neighbor involved_in IEA GOC GO_REF:0000108 NCBI chr 6:42,155,406...42,163,418
Ensembl chr 6:42,155,406...42,163,418 		JBrowse link
G GUCA1B guanylate cyclase activator 1B involved_in IEA GOC GO_REF:0000108 NCBI chr 6:42,183,284...42,194,956
Ensembl chr 6:42,183,284...42,194,956 		JBrowse link
G GUCA1C guanylate cyclase activator 1C involved_in IEA GOC GO_REF:0000108 NCBI chr 3:108,907,792...108,955,195
Ensembl chr 3:108,907,792...108,953,879 		JBrowse link
G GUCA2A guanylate cyclase activator 2A involved_in IEA GOC GO_REF:0000108 NCBI chr 1:42,162,690...42,164,745
Ensembl chr 1:42,162,690...42,164,745 		JBrowse link
G GUCA2B guanylate cyclase activator 2B involved_in IEA GOC GO_REF:0000108 NCBI chr 1:42,153,410...42,155,820
Ensembl chr 1:42,153,410...42,155,820 		JBrowse link
G LOC118142757 GUCA1ANB-GUCA1A readthrough involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:42,155,406...42,180,056
Ensembl chr 6:42,155,406...42,181,338 		JBrowse link
G NOS1 nitric oxide synthase 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 involved_in IBA
IMP
ISS		 (PMID:21873635)
(PMID:17502619)		 GO_Central
BHF-UCL
GO_Central
BHF-UCL		 PMID:17502619 PMID:21873635 GO_REF:0000024 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G RCVRN recoverin involved_in IEA GOC GO_REF:0000108 NCBI chr17:9,896,320...9,905,271
Ensembl chr17:9,896,320...9,905,271 		JBrowse link
positive regulation of L-dopa decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase involved_in IDA (PMID:19703902) ParkinsonsUK-UCL
ParkinsonsUK-UCL		 PMID:19703902 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
positive regulation of lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FTMT ferritin mitochondrial involved_in IDA (PMID:18160053) BHF-UCL
BHF-UCL		 PMID:18160053 NCBI chr 5:121,851,882...121,852,833
Ensembl chr 5:121,851,882...121,852,833 		JBrowse link
G FXN frataxin involved_in IDA
IMP		 (PMID:20053667)
(PMID:18160053)		 UniProt
UniProt
BHF-UCL
BHF-UCL		 PMID:18160053 PMID:20053667 NCBI chr 9:69,035,752...69,079,076
Ensembl chr 9:69,035,751...69,079,076 		JBrowse link
regulation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 1:40,040,240...40,072,648
Ensembl chr 1:40,040,233...40,072,649 		JBrowse link
G CAP2 cyclase associated actin cytoskeleton regulatory protein 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 6:17,393,595...17,557,780
Ensembl chr 6:17,393,595...17,557,780 		JBrowse link
G GNG7 G protein subunit gamma 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:2,511,219...2,702,694
Ensembl chr19:2,511,219...2,702,694 		JBrowse link
G NPFFR2 neuropeptide FF receptor 2 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr 4:72,032,000...72,148,305
Ensembl chr 4:72,031,902...72,148,305 		JBrowse link
regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRHR1 corticotropin releasing hormone receptor 1 involved_in IMP (PMID:23863939) UniProt
UniProt		 PMID:23863939 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G LINC02210-CRHR1 LINC02210-CRHR1 readthrough involved_in IMP (PMID:23863939) UniProt
UniProt		 PMID:23863939 NCBI chr17:45,620,346...45,835,828
Ensembl chr17:45,620,344...45,835,826
Ensembl chr17:45,620,344...45,835,826 		JBrowse link
regulation of ferrochelatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXN frataxin involved_in IDA (PMID:15123683) BHF-UCL
BHF-UCL		 PMID:15123683 NCBI chr 9:69,035,752...69,079,076
Ensembl chr 9:69,035,751...69,079,076 		JBrowse link
regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUCA1A guanylate cyclase activator 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3052899|PMID:15336959) Ensembl
MGI		 PMID:15336959 GO_REF:0000107 MGI:3052899 NCBI chr 6:42,173,364...42,180,056
Ensembl chr 6:42,173,364...42,181,338 		JBrowse link
G GUCA1B guanylate cyclase activator 1B acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3052899|PMID:15336959)
(PMID:21873635)		 MGI
GO_Central		 PMID:15336959 PMID:21873635 MGI:3052899 NCBI chr 6:42,183,284...42,194,956
Ensembl chr 6:42,183,284...42,194,956 		JBrowse link
G LOC118142757 GUCA1ANB-GUCA1A readthrough involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,155,406...42,180,056
Ensembl chr 6:42,155,406...42,181,338 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19771
    biological regulation 13757
      regulation of molecular function 3436
        regulation of catalytic activity 2579
          regulation of lyase activity 92
            negative regulation of lyase activity + 29
            positive regulation of lyase activity + 63
            regulation of L-dopa decarboxylase activity + 1
            regulation of aconitate hydratase activity + 4
            regulation of adenylate cyclase activity + 72
            regulation of cystathionine beta-synthase activity + 1
            regulation of ferrochelatase activity 1
            regulation of guanylate cyclase activity + 15
paths to the root