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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lyase activity
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Accession:GO:0051339 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
Synonyms:exact_synonym: lyase regulator


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activation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrhr growth hormone releasing hormone receptor IDA RGD PMID:9845677 RGD:1601338 NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IDA RGD PMID:8440169 RGD:2292602 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 IDA RGD PMID:8224221 RGD:70054 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597 		JBrowse link
negative regulation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 IDA RGD PMID:20410303 RGD:7242424 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578 		JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP RGD PMID:19574217 RGD:6902943 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Akap9 A-kinase anchoring protein 9 IMP RGD PMID:18772391 RGD:2313147 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IMP RGD PMID:15147298 RGD:2315493 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:10869375 RGD:632981 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA RGD PMID:8702617 RGD:1601497 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
positive regulation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:21143600 RGD:8693686 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Akap5 A-kinase anchoring protein 5 IDA RGD PMID:20410303 RGD:7242424 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578 		JBrowse link
G Gcg glucagon ISO RGD PMID:2235678 RGD:11556254 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IMP RGD PMID:15901773 RGD:1598578 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Guca1a guanylate cyclase activator 1A IDA RGD PMID:12545196 RGD:1599357 NCBI chr 9:13,588,988...13,598,566
Ensembl chr 9:13,588,525...13,598,565 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  biological_process 19527
    biological regulation 13192
      regulation of molecular function 323
        regulation of catalytic activity 195
          regulation of lyase activity 14
            negative regulation of lyase activity + 7
            positive regulation of lyase activity + 9
            regulation of L-dopa decarboxylase activity + 0
            regulation of aconitate hydratase activity + 0
            regulation of adenylate cyclase activity + 13
            regulation of cystathionine beta-synthase activity + 0
            regulation of ferrochelatase activity 0
            regulation of guanylate cyclase activity + 2
paths to the root