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ONTOLOGY REPORT - ANNOTATIONS

Term:chromosome separation
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Accession:GO:0051304 term browser browse the term
Definition:The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
Synonyms:narrow_synonym: rDNA separation
 related_synonym: chromatid release
 alt_id: GO:0034500


show annotations for term's descendants           Sort by:
 
chromosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Recql5 RecQ like helicase 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22013166)		 UniProt
RGD		 PMID:22013166 GO_REF:0000024 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` involved_in ISO
ISS		 (PMID:21549307)
GO_REF:0000024		 RGD
UniProt		 PMID:21549307 GO_REF:0000024 NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563 		JBrowse link
G Top3a DNA topoisomerase III alpha involved_in ISO (PMID:30057030) RGD PMID:30057030 NCBI chr10:45,419,219...45,457,356
Ensembl chr10:45,419,217...45,457,559 		JBrowse link
G Ttk Ttk protein kinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) RGD PMID:19010891 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO (PMID:18022368) RGD PMID:18022368 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24374861)		 UniProt
RGD		 PMID:24374861 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872 		JBrowse link
female meiosis chromosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncaph non-SMC condensin I complex, subunit H involved_in ISO MGI:1289164 (MGI:5784807|PMID:25961503) RGD PMID:25961503 MGI:5784807 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ncaph2 non-SMC condensin II complex, subunit H2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5784807|PMID:25961503)		 Ensembl
RGD		 PMID:25961503 GO_REF:0000107 MGI:5784807 NCBI chr 7:120,422,926...120,439,942
Ensembl chr 7:120,422,956...120,439,938 		JBrowse link
male meiosis chromosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G M1ap meiosis 1 associated protein involved_in ISO
IBA		 (MGI:5473951|PMID:23269666)
PMID:21873635		 RGD PMID:23269666 PMID:21873635 MGI:5473951, RGD:13792537 NCBI chr 4:115,445,910...115,536,745
Ensembl chr 4:115,455,397...115,536,487 		JBrowse link
meiotic chromosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Espl1 extra spindle pole bodies like 1, separase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984 		JBrowse link
G Ncapd3 non-SMC condensin II complex, subunit D3 acts_upstream_of_or_within ISO (MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:5317363 NCBI chr 8:25,437,067...25,506,375
Ensembl chr 8:25,437,123...25,506,373 		JBrowse link
meiotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk Ttk protein kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:5056148 (MGI:5049806|PMID:21558374)		 RGD PMID:21558374 PMID:21873635 MGI:5049806, RGD:13792537 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
meiotic spindle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO (PMID:10935642) RGD PMID:10935642 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
metaphase/anaphase transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc1 anaphase promoting complex subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273 		JBrowse link
G Anapc7 anaphase promoting complex subunit 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:34,131,214...34,160,819
Ensembl chr12:34,133,429...34,160,005 		JBrowse link
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO MGI:1333889|MGI:1856318|MGI:3589207 (MGI:3574170|PMID:15767571), (MGI:3588595|PMID:16025118) RGD PMID:15767571 PMID:16025118 MGI:3574170 MGI:3588595 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B acts_upstream_of_or_within ISO MGI:88039 (MGI:3574170|PMID:15767571) RGD PMID:15767571 MGI:3574170 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G Cdc16 cell division cycle 16 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550 		JBrowse link
G Cdc23 cell division cycle 23 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163 		JBrowse link
G Cdc27 cell division cycle 27 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:7736578)		 RGD PMID:7736578 PMID:21873635 RGD:13792537 NCBI chr10:89,400,931...89,449,823
Ensembl chr10:89,400,940...89,449,736 		JBrowse link
G Cit citron rho-interacting serine/threonine kinase acts_upstream_of_or_within ISO MGI:2447844 (MGI:3606716|PMID:12764032) RGD PMID:12764032 MGI:3606716 NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860 		JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 involved_in ISO (PMID:23532825) RGD PMID:23532825 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219 		JBrowse link
mitotic sister chromatid separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 involved_in ISO (PMID:22306653) RGD PMID:22306653 NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616 		JBrowse link
G Ncaph2 non-SMC condensin II complex, subunit H2 involved_in IBA
ISO
IEA		 PMID:21873635
(MGI:5805571|PMID:27737961)
GO_REF:0000107		 RGD
Ensembl		 PMID:27737961 PMID:21873635 GO_REF:0000107 MGI:5805571, RGD:13792537 NCBI chr 7:120,422,926...120,439,942
Ensembl chr 7:120,422,956...120,439,938 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO MGI:5287252 (MGI:5586612|PMID:24899574) RGD PMID:24899574 MGI:5586612 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor involved_in IBA
ISO
IEA
ISS		 PMID:21873635
(MGI:5318128|PMID:22405274)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22405274 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5318128, RGD:13792537 NCBI chr10:72,231,766...72,356,938
Ensembl chr10:72,231,801...72,355,805 		JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07000261.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17227893)
GO_REF:0000107		 RGD
Ensembl		 PMID:17227893 GO_REF:0000107 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:11943150) RGD PMID:11943150 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Aurkb aurora kinase B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 involved_in ISO
ISS		 (PMID:12805209)
GO_REF:0000024		 RGD
UniProt		 PMID:12805209 GO_REF:0000024 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B involved_in ISO
IBA		 (PMID:10477750)
PMID:21873635		 RGD PMID:10477750 PMID:21873635 RGD:13792537 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036 		JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) RGD PMID:12925705 MGI:2673075 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Haspin histone H3 associated protein kinase involved_in IEA
ISO		 GO_REF:0000107
(PMID:23071153)		 Ensembl
RGD		 PMID:23071153 GO_REF:0000107 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512 		JBrowse link
G Ik IK cytokine involved_in ISS
ISO		 GO_REF:0000024
(PMID:22351768)		 UniProt
RGD		 PMID:22351768 GO_REF:0000024 NCBI chr18:28,358,004...28,372,809
Ensembl chr18:28,357,977...28,378,832 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member acts_upstream_of_or_within ISO MGI:3844604 (MGI:3844372|PMID:19376971) RGD PMID:19376971 MGI:3844372 NCBI chr 8:73,842,344...73,844,248
Ensembl chr 8:73,842,344...73,844,248 		JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23455478)		 UniProt
RGD		 PMID:23455478 GO_REF:0000024 NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770 		JBrowse link
G Kntc1 kinetochore associated 1 involved_in ISO
IBA		 (PMID:11146660)
PMID:21873635		 RGD PMID:11146660 PMID:21873635 RGD:13792537 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in IBA
ISO		 PMID:21873635
(PMID:18981471), (PMID:9546394)		 RGD PMID:9546394 PMID:18981471 PMID:21873635 RGD:13792537 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:18981471)
MGI:2178781 (MGI:1930685|PMID:11201745)
PMID:21873635		 RGD PMID:11201745 PMID:18981471 PMID:21873635 MGI:1930685, RGD:13792537 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:23455478)		 Ensembl
UniProt
RGD		 PMID:23455478 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Psmg2 proteasome assembly chaperone 2 acts_upstream_of_or_within ISO (MGI:2388532|PMID:12147697) RGD PMID:12147697 MGI:2388532 NCBI chr18:61,208,669...61,227,671
Ensembl chr18:61,208,678...61,259,816 		JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127 		JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor involved_in IEA
ISO
IBA
ISS		 GO_REF:0000107
(MGI:5318128|PMID:22405274)
PMID:21873635
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22405274 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5318128, RGD:13792537 NCBI chr10:72,231,766...72,356,938
Ensembl chr10:72,231,801...72,355,805 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS		 (PMID:20133940)
GO_REF:0000024		 RGD
UniProt		 PMID:20133940 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISO
ISS		 (PMID:28553959)
GO_REF:0000024		 RGD
UniProt		 PMID:28553959 GO_REF:0000024 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074 		JBrowse link
G Ttk Ttk protein kinase involved_in IBA
ISO		 PMID:21873635
MGI:5056148 (MGI:5608719|PMID:25197064)		 RGD PMID:25197064 PMID:21873635 MGI:5608719, RGD:13792537 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
G Zfp207 zinc finger protein 207 involved_in ISO (PMID:24462186), (PMID:24462187) RGD PMID:24462186 PMID:24462187 NCBI chr10:65,385,823...65,397,591
Ensembl chr10:65,385,740...65,397,386 		JBrowse link
G Zw10 zw10 kinetochore protein involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:11146660), (PMID:15824131)
PMID:21873635		 HGNC-UCL
RGD		 PMID:11146660 PMID:15824131 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:49,396,541...49,424,743
Ensembl chr 8:49,396,545...49,421,805 		JBrowse link
G Zwilch zwilch kinetochore protein involved_in ISO
IBA		 (PMID:15824131)
PMID:21873635		 RGD PMID:15824131 PMID:21873635 RGD:13792537 NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916 		JBrowse link
G Zwint ZW10 interacting kinetochore protein involved_in ISO (PMID:15485811) RGD PMID:15485811 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mos MOS proto-oncogene, serine/threonine kinase involved_in IBA
ISO
IEA
ISS		 PMID:21873635
(MGI:67285|PMID:8015610), (MGI:67286|PMID:8015609)
(PMID:12533425)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:8015609 PMID:8015610 PMID:12533425 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:67285 MGI:67286, RGD:13792537 NCBI chr 5:16,859,957...16,861,264
Ensembl chr 5:16,859,957...16,861,264 		JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:11988738), (PMID:16921029) RGD PMID:11988738 PMID:16921029 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Rad21 RAD21 cohesin complex component involved_in ISO (MGI:1340883|PMID:10375619) RGD PMID:10375619 MGI:1340883 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
negative regulation of mitotic sister chromatid separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pttg1 PTTG1 regulator of sister chromatid separation, securin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
positive regulation of chromosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncapd2 non-SMC condensin I complex, subunit D2 involved_in ISO (MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:5317363 NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020 		JBrowse link
G Ncapd3 non-SMC condensin II complex, subunit D3 involved_in ISO (MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:5317363 NCBI chr 8:25,437,067...25,506,375
Ensembl chr 8:25,437,123...25,506,373 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G involved_in ISO (MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:5317363 NCBI chr14:65,404,235...65,432,902
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncapg2 non-SMC condensin II complex, subunit G2 involved_in ISO (MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:5317363 NCBI chr 6:137,342,449...137,418,083
Ensembl chr 6:137,342,943...137,415,159 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H involved_in ISO (MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:5317363 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ncaph2 non-SMC condensin II complex, subunit H2 involved_in ISO
IEA		 (MGI:5317363|PMID:21795393)
GO_REF:0000107		 RGD
Ensembl		 PMID:21795393 GO_REF:0000107 MGI:5317363 NCBI chr 7:120,422,926...120,439,942
Ensembl chr 7:120,422,956...120,439,938 		JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 involved_in ISO (PMID:23921553) RGD PMID:23921553 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISO
ISS		 (PMID:27206388)
GO_REF:0000024		 RGD
UniProt		 PMID:27206388 GO_REF:0000024 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 involved_in ISO (MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:5317363 NCBI chr 5:66,806,882...66,853,478
Ensembl chr 5:66,807,011...66,853,242 		JBrowse link
G Smc4 structural maintenance of chromosomes 4 involved_in ISO (MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:5317363 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571 		JBrowse link
positive regulation of metaphase/anaphase transition of meiosis I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk15 mitogen-activated protein kinase 15 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6154463|PMID:23351492)		 Ensembl
RGD		 PMID:23351492 GO_REF:0000107 MGI:6154463 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19229290)		 UniProt
Ensembl
RGD		 PMID:19229290 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934 		JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:22898774) RGD PMID:22898774 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in ISO (MGI:4839685|PMID:20870947)
(PMID:20870947), (PMID:22898774), (PMID:8824189)		 RGD PMID:8824189 PMID:20870947 PMID:22898774 MGI:4839685 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO (PMID:25743205) RGD PMID:25743205 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)		 RGD PMID:20870947 MGI:4839685 NCBI chr16:76,423,245...76,448,712
Ensembl chr16:76,423,245...76,448,712 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:18981471), (PMID:19273613)		 UniProt
RGD		 PMID:18981471 PMID:19273613 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc11 anaphase promoting complex subunit 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:105,875,209...105,886,307 JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:33,748,714...33,781,709
Ensembl chr12:33,748,735...33,781,781 		JBrowse link
G Anapc7 anaphase promoting complex subunit 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:34,131,214...34,160,819
Ensembl chr12:34,133,429...34,160,005 		JBrowse link
G Cdc16 cell division cycle 16 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550 		JBrowse link
G Cdc23 cell division cycle 23 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163 		JBrowse link
G Cdc27 cell division cycle 27 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:89,400,931...89,449,823
Ensembl chr10:89,400,940...89,449,736 		JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) RGD PMID:12925705 MGI:2673075 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Cul3 cullin 3 involved_in ISO (PMID:17543862) RGD PMID:17543862 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
ISS		 (PMID:19502785)
GO_REF:0000024		 RGD
UniProt		 PMID:19502785 GO_REF:0000024 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA		 (PMID:20551165)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551165 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
regulation of chromosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISO
ISS		 (PMID:11704824)
GO_REF:0000024		 RGD
UniProt		 PMID:11704824 GO_REF:0000024 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO (PMID:11704824) RGD PMID:11704824 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080 		JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex subunit 15 involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:21926987)		 UniProt
RGD		 PMID:21926987 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:156,238,640...156,266,005
Ensembl chr 1:156,262,841...156,268,145 		JBrowse link
G Ccnb1 cyclin B1 involved_in ISO (PMID:18195732) RGD PMID:18195732 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19282672)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19282672 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Dusp1 dual specificity phosphatase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17724024)
GO_REF:0000107		 RGD
Ensembl		 PMID:17724024 GO_REF:0000107 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO (MGI:5448515|PMID:21853124) RGD PMID:21853124 MGI:5448515 NCBI chr 7:28,364,169...28,412,039
Ensembl chr 7:28,364,033...28,410,053 		JBrowse link
regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc4 anaphase promoting complex subunit 4 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:58,125,995...58,159,253
Ensembl chr14:58,125,995...58,157,770 		JBrowse link
G Cdc23 cell division cycle 23 involved_in ISO (PMID:9790767) RGD PMID:9790767 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163 		JBrowse link
G Cdc26 cell division cycle 26 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:75,844,852...75,859,837 JBrowse link
G Cdc6 cell division cycle 6 involved_in ISO (PMID:21041660) RGD PMID:21041660 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:2022189) RGD PMID:2022189 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 involved_in ISO (PMID:24163370) RGD PMID:24163370 NCBI chr 9:55,359,462...55,753,106
Ensembl chr 9:55,365,203...55,580,327 		JBrowse link
G Nek6 NIMA-related kinase 6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:14563848)		 UniProt
RGD		 PMID:14563848 GO_REF:0000024 NCBI chr 3:22,284,269...22,356,302
Ensembl chr 3:22,284,279...22,395,990 		JBrowse link
G Plk1 polo-like kinase 1 involved_in ISO (PMID:21041660), (PMID:23509069) RGD PMID:21041660 PMID:23509069 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Riok2 RIO kinase 2 involved_in ISO (PMID:21880710) RGD PMID:21880710 NCBI chr 1:58,103,132...58,119,397
Ensembl chr 1:58,103,084...58,120,512 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
regulation of mitotic sister chromatid separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS		 (PMID:20133940)
GO_REF:0000024		 RGD
UniProt		 PMID:20133940 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
resolution of meiotic recombination intermediates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729 		JBrowse link
G Cenps centromere protein S involved_in ISO (PMID:20347428) RGD PMID:20347428 NCBI chr 5:159,563,917...159,573,534 JBrowse link
G Cenpx centromere protein X involved_in ISO (PMID:20347428) RGD PMID:20347428 NCBI chr10:105,991,469...105,994,411 JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:79,586,736...79,595,515
Ensembl chr10:79,586,729...79,595,435 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:13,913,216...13,915,991
Ensembl chr10:13,913,221...13,915,968 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ercc4l1 excision repair cross-complementing rodent repair deficiency, complementation group 4-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:954,927...983,651
Ensembl chr10:954,977...983,174 		JBrowse link
G Fancm FA complementation group M involved_in ISO (PMID:20347428) RGD PMID:20347428 NCBI chr 6:83,126,903...83,180,455
Ensembl chr 6:83,127,093...83,180,028 		JBrowse link
G Hfm1 helicase for meiosis 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5477835|PMID:23555294)		 RGD PMID:23555294 PMID:21873635 MGI:5477835, RGD:13792537 NCBI chr14:2,857,251...2,943,766
Ensembl chr14:2,856,599...2,939,238 		JBrowse link
G Meiob meiosis specific with OB-fold involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5527015|PMID:24068956), (MGI:5538413|PMID:24240703)
PMID:21873635		 UniProt
RGD		 PMID:24068956 PMID:24240703 PMID:21873635 GO_REF:0000024 MGI:5527015 MGI:5538413, RGD:13792537 NCBI chr10:13,833,170...13,865,684
Ensembl chr10:13,833,750...13,865,046 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857946 (MGI:1340178|PMID:10385520), (MGI:2386157|PMID:12217320)
GO_REF:0000107		 RGD
Ensembl		 PMID:10385520 PMID:12217320 GO_REF:0000107 MGI:1340178 MGI:2386157 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:202,790,295...202,796,008
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
G Rmi1 RecQ mediated genome instability 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:6,256,537...6,264,523
Ensembl chr17:6,256,450...6,264,695 		JBrowse link
G Shoc1 shortage in chiasmata 1 involved_in ISO
IBA		 (MGI:6159552|PMID:29742103)
PMID:21873635		 RGD PMID:29742103 PMID:21873635 MGI:6159552, RGD:13792537 NCBI chr 5:73,864,423...73,956,487
Ensembl chr 5:73,866,334...73,956,444 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Tex11 testis expressed 11 acts_upstream_of_or_within ISO MGI:3526163 (MGI:3774244|PMID:18316482) RGD PMID:18316482 MGI:3774244 NCBI chr  X:65,932,904...66,196,525
Ensembl chr  X:65,932,988...66,196,187 		JBrowse link
G Top2a DNA topoisomerase II alpha involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      chromosome segregation 346
        chromosome separation 102
          centromere separation + 0
          meiotic chromosome separation + 26
          mitotic sister chromatid separation + 66
          negative regulation of chromosome separation + 46
          positive regulation of chromosome separation + 25
          regulation of chromosome separation + 78
Path 2
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cell cycle 1594
        cell cycle process 1220
          chromosome separation 102
            centromere separation + 0
            meiotic chromosome separation + 26
            mitotic sister chromatid separation + 66
            negative regulation of chromosome separation + 46
            positive regulation of chromosome separation + 25
            regulation of chromosome separation + 78
paths to the root