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ONTOLOGY REPORT - ANNOTATIONS


Term:centrosome separation
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Accession:GO:0051299 term browser browse the term
Definition:The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.


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centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cntrob centrobin, centriole duplication and spindle assembly protein JBrowse link 10 55,901,929 55,927,121 RGD:1624291
RGD:13792537
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek2l1 NIMA (never in mitosis gene a)-related kinase 2-like 1 JBrowse link 8 15,940,934 15,942,589 RGD:1600115
mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:1600115
RGD:1624291
G Kif11 kinesin family member 11 JBrowse link 1 256,035,866 256,088,299 RGD:1624291
RGD:1600115
G Nde1 nudE neurodevelopment protein 1 JBrowse link 10 860,513 904,624 RGD:13792537
G Ndel1 nudE neurodevelopment protein 1-like 1 JBrowse link 10 55,398,919 55,456,654 RGD:1624291
RGD:13792537
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
RGD:1600115
positive regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nsfl1c NSFL1 cofactor JBrowse link 3 146,980,923 147,005,478 RGD:1600115
RGD:1624291
G Ranbp1 RAN binding protein 1 JBrowse link 11 86,890,585 86,898,818 RGD:1624291
RGD:13792537
G Ubxn2b UBX domain protein 2B JBrowse link 5 19,285,368 19,314,199 RGD:1600115
RGD:1624291
regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep85 centrosomal protein 85 JBrowse link 5 152,359,693 152,406,530 RGD:1624291
RGD:1600115
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:1624291
RGD:1600115
G Kif11 kinesin family member 11 JBrowse link 1 256,035,866 256,088,299 RGD:1624291
RGD:1600115
G Map9 microtubule-associated protein 9 JBrowse link 2 181,331,426 181,367,245 RGD:1624291
RGD:1600115
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek2l1 NIMA (never in mitosis gene a)-related kinase 2-like 1 JBrowse link 8 15,940,934 15,942,589 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    cellular process 17125
      cell cycle process 1171
        centrosome separation 14
          mitotic centrosome separation + 13
Path 2
Term Annotations click to browse term
  biological_process 19245
    cellular component organization or biogenesis 6449
      cellular component organization 6239
        organelle organization 3773
          cytoskeleton organization 1384
            microtubule cytoskeleton organization 598
              microtubule organizing center organization 141
                centrosome cycle 130
                  centrosome separation 14
                    mitotic centrosome separation + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.