Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:NAD binding
go back to main search page
Accession:GO:0051287 term browser browse the term
Definition:Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
Synonyms:exact_synonym: nicotinamide adenine dinucleotide binding
 related_synonym: NAD or NADH binding
 alt_id: GO:0051288


show annotations for term's descendants           Sort by:
 
NAD binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07024795.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr16:16,949,232...16,950,239 JBrowse link
G AABR07025010.1 IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr16:25,773,602...25,774,845 JBrowse link
G AABR07030729.1 IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr10:102,288,836...102,289,837 JBrowse link
G AABR07032392.1 IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr18:63,824,407...63,825,408 JBrowse link
G AABR07034445.1 IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr11:72,108,963...72,109,964 JBrowse link
G AABR07053879.1 IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr 3:132,052,612...132,053,613 JBrowse link
G AABR07070043.1 IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr 8:45,561,390...45,562,574 JBrowse link
G AABR07071101.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 8:100,260,049...100,261,080 JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) IDA RGD PMID:10094961, PMID:1558299 RGD:1642948, RGD:1642949 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide IDA
ISO
(PMID:10407146) RGD PMID:10407146, PMID:2774584 RGD:1358222 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide IDA RGD PMID:10829036 RGD:631904 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532
JBrowse link
G Ahcy adenosylhomocysteinase IDA RGD PMID:2910349 RGD:1598902 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 ISS PMID:12693930 CAFA PMID:12693930 RGD:12793038 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 ISS PMID:12693930 CAFA PMID:12693930 RGD:12793038 NCBI chr 1:240,584,233...240,601,843
Ensembl chr 1:240,562,423...240,601,744
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 IDA RGD PMID:12871571, PMID:12527414, PMID:7262085 RGD:1304407, RGD:1600514, RGD:1600512 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 IDA RGD PMID:10467734 RGD:2313412 NCBI chr13:85,580,828...85,597,497
Ensembl chr13:85,580,828...85,597,493
JBrowse link
G Aox1 aldehyde oxidase 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
JBrowse link
G Aox2 aldehyde oxidase 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:65,175,455...65,265,149
Ensembl chr 9:65,177,511...65,265,149
JBrowse link
G Aox3 aldehyde oxidase 3 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:65,013,831...65,099,433
Ensembl chr 9:65,013,862...65,099,433
JBrowse link
G Aox4 aldehyde oxidase 4 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:65,110,330...65,167,188
Ensembl chr 9:65,110,325...65,167,192
JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 ISO
IEA
(PMID:16380372)
GO_REF:0000107
RGD
Ensembl
PMID:16380372 GO_REF:0000107 NCBI chr 2:240,461,505...240,482,149
Ensembl chr 2:240,461,505...240,482,145
JBrowse link
G Ctbp1 C-terminal binding protein 1 IDA
IEA
PMID:19351597
GO_REF:0000002
InterPro PMID:19351597 GO_REF:0000002, RGD:8553313 NCBI chr14:82,762,109...82,789,350
Ensembl chr14:82,762,190...82,789,319
JBrowse link
G Ctbp2 C-terminal binding protein 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:205,001,354...205,030,565
Ensembl chr 1:205,001,396...205,040,755
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 IDA RGD PMID:14609324 RGD:1599772 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Dld dihydrolipoamide dehydrogenase IDA RGD PMID:3753688 RGD:2289893 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gapdh-ps2 glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr16:25,773,573...25,774,863 JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr 1:89,180,063...89,195,347
Ensembl chr 1:89,180,063...89,194,602
JBrowse link
G Glyr1 glyoxylate reductase 1 homolog IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:10,725,830...10,759,471
Ensembl chr10:10,725,819...10,761,279
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 IDA RGD PMID:9550546 RGD:1641824 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191
JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase IDA RGD PMID:2689175 RGD:1599320 NCBI chr 5:60,528,981...60,538,410
Ensembl chr 5:60,528,997...60,538,375
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha IDA RGD PMID:1730633 RGD:1600572 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:82,604,369...82,702,429
Ensembl chr 4:82,604,373...82,702,429
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase ISS
ISO
GO_REF:0000024
(PMID:10198228), (PMID:15581601)
UniProt
RGD
PMID:10198228, PMID:15581601 GO_REF:0000024 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IDA RGD PMID:15761036 RGD:1625105 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 IDA RGD PMID:11023795 RGD:2302237 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IDA RGD PMID:1955079 RGD:1625116
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:122,808,564...122,813,638
Ensembl chr 3:122,808,564...122,813,583
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr  X:156,999,803...157,008,735
Ensembl chr  X:156,999,826...157,008,733
JBrowse link
G Ldha lactate dehydrogenase A IDA RGD PMID:17447164 RGD:1624966 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Ldhb lactate dehydrogenase B IDA RGD PMID:17447164 RGD:1624966 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G LOC108351137 glyceraldehyde-3-phosphate dehydrogenase IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr 5:115,649,077...115,650,141
Ensembl chr 5:115,649,046...115,650,340
Ensembl chr 4:115,649,046...115,650,340
JBrowse link
G LOC108351683 glyceraldehyde-3-phosphate dehydrogenase pseudogene IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:45,561,393...45,562,483 JBrowse link
G LOC108352348 glyceraldehyde-3-phosphate dehydrogenase pseudogene IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr11:72,108,963...72,110,027 JBrowse link
G LOC303448 similar to glyceraldehyde-3-phosphate dehydrogenase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:78,687,653...78,696,097
Ensembl chr10:78,687,661...78,690,857
JBrowse link
G Mdh1 malate dehydrogenase 1 IDA
ISO
(PMID:10075524) RGD PMID:10075524, PMID:17447164 RGD:1624966 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G Me1 malic enzyme 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Me2 malic enzyme 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:69,737,515...69,784,099
Ensembl chr18:69,738,686...69,784,099
JBrowse link
G Me3 malic enzyme 3 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:153,861,535...154,058,608
Ensembl chr 1:153,861,569...154,056,654
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:89,606,848...89,623,506
Ensembl chr13:89,606,840...89,619,398
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:219,254,293...219,259,328
Ensembl chr 1:219,254,279...219,259,448
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:52,189,523...52,283,095
Ensembl chr 2:52,189,529...52,282,548
JBrowse link
G Nudt6 nudix hydrolase 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:124,134,301...124,149,824
Ensembl chr 2:124,134,307...124,149,636
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IDA RGD PMID:16302026, PMID:15857403 RGD:1601079, RGD:1601082 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Phgdh phosphoglycerate dehydrogenase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Sord sorbitol dehydrogenase ISO (PMID:12962626) RGD PMID:12962626 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
NAD+ binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 IEA
ISO
GO_REF:0000107
(MGI:3692370|PMID:16241904)
Ensembl
RGD
PMID:16241904 GO_REF:0000107, MGI:3692370 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Cryl1 crystallin, lambda 1 ISO
ISS
(PMID:15809331)
GO_REF:0000024
RGD
UniProt
PMID:15809331 GO_REF:0000024 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584
JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO (PMID:12193607) RGD PMID:12193607 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase ISO
ISS
(PMID:10840044)
GO_REF:0000024
RGD
UniProt
PMID:10840044 GO_REF:0000024 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase ISS
ISO
GO_REF:0000024
(PMID:16828555), (PMID:21072165)
UniProt
RGD
PMID:16828555, PMID:21072165 GO_REF:0000024 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 ISO (PMID:16061477) RGD PMID:16061477 NCBI chr11:68,105,442...68,137,509
Ensembl chr11:68,105,369...68,137,535
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 NOT ISO (PMID:16061477) RGD PMID:16061477 NCBI chr11:67,724,071...67,758,027
Ensembl chr11:67,724,076...67,756,799
JBrowse link
G Sirt1 sirtuin 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sirt2 sirtuin 2 ISO
IBA
IEA
(PMID:11427894)
PMID:21873635
GO_REF:0000104
RGD
UniProt
PMID:11427894, PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Sirt3 sirtuin 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Sirt4 sirtuin 4 IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr12:46,862,358...46,876,593
Ensembl chr12:46,868,416...46,876,592
JBrowse link
G Sirt5 sirtuin 5 ISS
ISO
GO_REF:0000024
(PMID:21908771), (PMID:22076378)
UniProt
RGD
PMID:21908771, PMID:22076378 GO_REF:0000024 NCBI chr17:23,986,710...24,013,854
Ensembl chr17:23,986,758...24,013,881
JBrowse link
G Sirt6 sirtuin 6 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:10,937,622...10,943,048
Ensembl chr 7:10,937,599...10,943,063
JBrowse link
G Sirt7 sirtuin 7 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:109,796,046...109,802,821
Ensembl chr10:109,796,020...109,802,739
JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 ISO
IBA
(PMID:23072385)
PMID:21873635
RGD PMID:23072385, PMID:21873635 RGD:13792537 NCBI chr 9:11,165,006...11,240,329
Ensembl chr 9:11,164,715...11,339,790
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 NOT ISO (PMID:25635049) RGD PMID:25635049 NCBI chr 4:66,012,111...66,062,160
Ensembl chr 4:66,011,915...66,062,089
JBrowse link
NADH binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IDA RGD PMID:21276780 RGD:7241587 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Cryz crystallin zeta NOT ISO
ISS
(PMID:17497241)
GO_REF:0000024
RGD
UniProt
PMID:17497241 GO_REF:0000024 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 ISO
ISS
(PMID:25203508)
GO_REF:0000024
RGD
UniProt
PMID:25203508 GO_REF:0000024 NCBI chr20:3,817,212...3,819,316
Ensembl chr20:3,817,179...3,819,235
JBrowse link
G Qdpr quinoid dihydropteridine reductase IPI
IBA
PMID:21873635 RGD
GO_Central
PMID:8631945, PMID:21873635 RGD:5128583, RGD:13792537 NCBI chr14:70,164,682...70,178,284
Ensembl chr14:70,164,650...70,178,284
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO (PMID:25531177) RGD PMID:25531177 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    binding 17224
      small molecule binding 2536
        nucleotide binding 2162
          NAD binding 81
            NAD+ binding 16
            NADH binding 5
Path 2
Term Annotations click to browse term
  molecular_function 20457
    binding 17224
      organic cyclic compound binding 5830
        nucleoside phosphate binding 2162
          nucleotide binding 2162
            NAD binding 81
              NAD+ binding 16
              NADH binding 5
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.